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Stem Cell Based Therapy For Neurodegenerative Diseases


Stem Cell Based Therapy For Neurodegenerative Diseases
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Stem Cell Based Therapy For Neurodegenerative Diseases


Stem Cell Based Therapy For Neurodegenerative Diseases
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Author : Fabin Han
language : en
Publisher: Springer Nature
Release Date : 2020-10-26

Stem Cell Based Therapy For Neurodegenerative Diseases written by Fabin Han and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-26 with Science categories.


This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.



Handbook Of Stem Cell Applications


Handbook Of Stem Cell Applications
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Author : Khawaja H. Haider
language : en
Publisher: Springer Nature
Release Date :

Handbook Of Stem Cell Applications written by Khawaja H. Haider and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Developing Stem Cell Based Therapies For Neural Repair


Developing Stem Cell Based Therapies For Neural Repair
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Author : Clare Parish
language : en
Publisher: Frontiers Media SA
Release Date : 2015-01-28

Developing Stem Cell Based Therapies For Neural Repair written by Clare Parish and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-28 with Neural stem cells categories.


Current pharmacotherapies and surgical intervention provide limited benefit in the treatment of neural injuries or halting disease progression and has resulted in significant hope for the successes of stem cell research. The properties of stem cells render them appropriate for cell replacement therapy, endogenous repair, disease modeling as well as high-throughput drug screening and development. Such applications will aide in increasing our knowledge and developing treatments for neurodegenerative disorders such as Parkinson’s disease and Huntington’s diseases as well as neural traumas including ischemic brain damage and traumatic brain injury. This Frontiers Research topic encouraged contributions from the general field of stem cell biology, with a particular emphasis on utilizing these cells to develop new therapies for neural repair. Related articles deal with issues such as: breakthroughs in stem cell proliferation/differentiation methodologies, using pluripotent and neural stem cells for transplantation and endogenous repair, the use of patient derived stem cells for disease modeling, using stem cells for drug discovery as well as the ethical issues related to the use of stem cells.



Stem Cells And Neurodegenerative Diseases


Stem Cells And Neurodegenerative Diseases
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Author : Laurent Lescaudron
language : en
Publisher: CRC Press
Release Date : 2014-03-17

Stem Cells And Neurodegenerative Diseases written by Laurent Lescaudron and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-17 with Medical categories.


This book explores the potential of stem cells for ameliorating the quality of life of patients with neurological and neurodegenerative diseases. It discusses results of pre-clinical investigations and case studies on the effects of stem cell transplantation on cell death, as well as to promote/stimulate neuroprotection after brain and spinal cord



Current Challenges In Cell Therapy For Neurodegenerative Diseases


Current Challenges In Cell Therapy For Neurodegenerative Diseases
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Author :
language : en
Publisher: Academic Press
Release Date : 2022-11-22

Current Challenges In Cell Therapy For Neurodegenerative Diseases written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-22 with Medical categories.


Cell Transplantation and Gene Therapy in Neurodegenerative Disease, Volume 166 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors who cover Challenges in translating a cell therapy to GMP, The challenges in developing a cell therapy for Huntington’s disease, Challenges of cell therapies for retinal diseases, Challenges of gene therapy in Huntington’s Disease, Technological advances and barriers to gene therapy, Considerations in the development of cell therapy modulation for spinal cord injury treatment, Challenges of developing glial cell therapy for ALS, and more. Other chapters in this comprehensive release include Exploring cell and gene therapy in current animal models of Parkinson’s and Huntington’s disease, Considerations for the use of biomaterials to support cell therapy in degenerative disease, Neurosurgical challenges/innovations in cell and gene therapy delivery, Neuroimaging: the challenge of harnessing imaging tools to facilitate cell and gene therapy in neurodegenerative diseases/The contribution and challenges for imaging in advanced therapies of movement disorders, Considerations for clinical trial design for novel advanced therapeutics in neurodegenerative disease, and More than a trial participant: The role of the patient in ATMP development and trials for neurodegenerative disease. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in International Review on Neurobiology serials Updated release includes the latest information on Cell Transplantation and Gene Therapy in Neurodegenerative Disease



Applications Of Stem Cells And Derived Exosomes In Neurodegenerative Disorders


Applications Of Stem Cells And Derived Exosomes In Neurodegenerative Disorders
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Author : Sadaf Jahan
language : en
Publisher: Springer Nature
Release Date :

Applications Of Stem Cells And Derived Exosomes In Neurodegenerative Disorders written by Sadaf Jahan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Cell Therapy


Cell Therapy
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Author : Dwaine F. Emerich
language : en
Publisher: Springer
Release Date : 2017-08-25

Cell Therapy written by Dwaine F. Emerich and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-25 with Medical categories.


This volume provides a comprehensive, state-of-the art review of the field of cell therapy. The volume begins with an overview of the breadth of the field and then turns to overviews of imaging technologies that can aid in both safety and efficacy evaluations. The book then turns to numerous contributions detailing the rapidly growing field of stem cell therapies. These sections cover our understanding of the natural roles of stem cells in biology and human disease and then touches on several of the more prominent areas where stem cells are moving rapidly into clinical evaluation including neurodegenerative diseases, muscular dystrophy, cardiac repair, and diabetes. The volume concludes with contributions from experts in oncology, ophthalmology, stem cells, 3-D printing, and biomaterials where the convergence of expertise is leading to unprecedented insights into how to minutely control the in vivo fate and function of transplanted and/or endogeneously mobilized cells. Finally, the book provides insights into the pivotal relationship between academic and industrial partnerships. This volume is designed to touch on the major areas where the field will make its greatest and most immediate clinical impacts. This text will provide a useful resource for physicians and researchers interested in the rapidly changing filed of cell therapy.



Neural Stem Cells In Health And Disease


Neural Stem Cells In Health And Disease
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Author : Ashok K Shetty
language : en
Publisher: World Scientific Publishing Company
Release Date : 2015-08-28

Neural Stem Cells In Health And Disease written by Ashok K Shetty and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-28 with Science categories.


This book is a comprehensive guide on neural stem cell behavior in health and disease. The book confers the altered behavior of endogenous neural stem cells in neurodegenerative disease conditions and the prospects of neural stem cell therapy for alleviating brain dysfunction in a variety of neurodegenerative disorders. Neural stem cell activity and neurogenesis in the adult brain is now confirmed in virtually all mammalian species including humans. Hence, a series of chapters in the first half of the book discusses the current knowledge on mechanisms of neural stem cell activity, the extent and functional significance of neurogenesis in the adult brain under normal, aged and disease environments, the susceptibility of neural stem cells and the plasticity of neurogenesis to alcohol, drugs of abuse and anesthetic agents, and advanced techniques that trigger neurogenesis in non-neurogenic regions. A second series of chapters in this book are focused on discussing the promise and efficacy of grafting of neural stem cells and/or other stem cells for treating neurological disorders such as Parkinson's disease, stroke, temporal lobe epilepsy, Alzheimer's disease and spinal cord injury. The final chapter confers on advances that are made in manufacturing a variety of neural cell types from human pluripotent stem cells that can be used as donor cells for cell transplantation.



Frontiers In Stem Cell And Regenerative Medicine Research


Frontiers In Stem Cell And Regenerative Medicine Research
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Author : Atta-ur-Rahman Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2017-07-06

Frontiers In Stem Cell And Regenerative Medicine Research written by Atta-ur-Rahman Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-06 with Science categories.


Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. The sixth volume of this series features reviews on roles of mesenchymal stem cells in cartilage regeneration and bone regeneration, liver regeneration, cardiogenesis, cardiomyocyte differentiation, and regenerative therapy for neurodegenerative disorders.



Regenerative Medicine


Regenerative Medicine
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Author : Krothapalli Raja Surya Sambasiva Rao
language : en
Publisher:
Release Date : 2009-11-01

Regenerative Medicine written by Krothapalli Raja Surya Sambasiva Rao and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-01 with Regenerative medicine categories.


Stem cells (unspecialized cells) have the ability to self-replicate and transform into an array of specialized cells. These cells have two unique properties: self-renewal capacity and the ability to undergo differentiation pathways or enter terminal divisions to yield an organized tissues or functional blood cells. Both embryonic and adult stem cells, therefore, can be used to generate healthy tissues and replace the damaged ones. For instance, they can be used to produce insulin-secreting cells for the treatment of type I diabetes, to generate liver cells for patients with liver failure, to treat neurodegenerative disorders like Alzheimer's and Parkinson's disease, to cure myocardial infarction etc. Thus, we envisage a possibility to restore normal functions with the application of stem cells. Stem cell research focuses on the potential applications of stem cells. This advancing field of science is making the possibility of cell-based therapies to treat myriad diseases. In the present book, we focus on stem cells and their applications. This book will be useful for students who are interested in the area of regenerative medicine, health sciences and biotechnology.