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Applications Of Stem Cells And Derived Exosomes In Neurodegenerative Disorders


Applications Of Stem Cells And Derived Exosomes In Neurodegenerative Disorders
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Applications Of Stem Cells And Derived Exosomes In Neurodegenerative Disorders


Applications Of Stem Cells And Derived Exosomes In Neurodegenerative Disorders
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Author : Sadaf Jahan
language : en
Publisher: Springer Nature
Release Date :

Applications Of Stem Cells And Derived Exosomes In Neurodegenerative Disorders written by Sadaf Jahan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Handbook Of Stem Cell Applications


Handbook Of Stem Cell Applications
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Author : Khawaja H. Haider
language : en
Publisher: Springer Nature
Release Date :

Handbook Of Stem Cell Applications written by Khawaja H. Haider and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Mesenchymal Stem Cell Derived Exosomes


Mesenchymal Stem Cell Derived Exosomes
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Author : Yaoliang Tang
language : en
Publisher: Academic Press
Release Date : 2015-09-02

Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-02 with Science categories.


Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies



Stem Cell Based Therapy For Neurodegenerative Diseases


Stem Cell Based Therapy For Neurodegenerative Diseases
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Author : Fabin Han
language : en
Publisher: Springer Nature
Release Date : 2020-10-26

Stem Cell Based Therapy For Neurodegenerative Diseases written by Fabin Han and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-26 with Science categories.


This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.



Neural Stem Cells In Health And Diseases


Neural Stem Cells In Health And Diseases
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Author : Ashok K. Shetty
language : en
Publisher: World Scientific Publishing Company Incorporated
Release Date : 2015

Neural Stem Cells In Health And Diseases written by Ashok K. Shetty and has been published by World Scientific Publishing Company Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.


This book is a comprehensive guide on neural stem cell behavior in health and disease. It will cover the altered behavior of endogenous neural stem cells in neurodegenerative conditions and the prospects of neural stem cell therapy for alleviating brain dysfunction in a variety of neurodegenerative disorders. First set of chapters will focus on neural stem cell proliferation, neuronal differentiation and maturation of progeny of cells derived from neural stem cells in brain regions, such as the hippocampus and the subventricular zone of the forebrain. Neural stem cell behavior in young and aged brains and functional implications of altered neural stem cell behavior will be discussed as well. The second set of chapters will cover altered behavior of endogenous neural stem cells and their functional implications in disorders, such as temporal lobe epilepsy, cancer, traumatic brain injury, stroke, Alzheimer's disease, addiction and alcohol use. The third set of chapters will discuss prospects of stem cell therapy for various neurological disorders, which will comprise of their behavior after grafting and functional recovery mediated by them. Additional chapters will discuss how to generate the right neural cell types from induced pluripotent stem cells for screening and cell therapy of central nervous system disorders.



Exosomes Stem Cells And Microrna


Exosomes Stem Cells And Microrna
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Author : Karl L. Mettinger
language : en
Publisher: Springer
Release Date : 2018-05-12

Exosomes Stem Cells And Microrna written by Karl L. Mettinger and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-12 with Science categories.


This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries.



Role Of Exosomes In Biological Communication Systems


Role Of Exosomes In Biological Communication Systems
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Author : Faisal A. Alzahrani
language : en
Publisher: Springer Nature
Release Date : 2020-11-20

Role Of Exosomes In Biological Communication Systems written by Faisal A. Alzahrani and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-20 with Medical categories.


This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.



Stem Cells And Neurodegenerative Diseases


Stem Cells And Neurodegenerative Diseases
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Author : Laurent Lescaudron
language : en
Publisher: CRC Press
Release Date : 2014-03-17

Stem Cells And Neurodegenerative Diseases written by Laurent Lescaudron and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-17 with Medical categories.


This book explores the potential of stem cells for ameliorating the quality of life of patients with neurological and neurodegenerative diseases. It discusses results of pre-clinical investigations and case studies on the effects of stem cell transplantation on cell death, as well as to promote/stimulate neuroprotection after brain and spinal cord injury through trophic support, cell replacement and remyelination. The book covers the maintenance of the balance between stem cells and their progenitors within their niche, both under normal and degenerative processes and with ischemic stroke, multiple sclerosis, and brain tumor.



Developing Stem Cell Based Therapies For Neural Repair


Developing Stem Cell Based Therapies For Neural Repair
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Author : Clare Parish
language : en
Publisher: Frontiers Media SA
Release Date : 2015-01-28

Developing Stem Cell Based Therapies For Neural Repair written by Clare Parish and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-28 with Neural stem cells categories.


Current pharmacotherapies and surgical intervention provide limited benefit in the treatment of neural injuries or halting disease progression and has resulted in significant hope for the successes of stem cell research. The properties of stem cells render them appropriate for cell replacement therapy, endogenous repair, disease modeling as well as high-throughput drug screening and development. Such applications will aide in increasing our knowledge and developing treatments for neurodegenerative disorders such as Parkinson’s disease and Huntington’s diseases as well as neural traumas including ischemic brain damage and traumatic brain injury. This Frontiers Research topic encouraged contributions from the general field of stem cell biology, with a particular emphasis on utilizing these cells to develop new therapies for neural repair. Related articles deal with issues such as: breakthroughs in stem cell proliferation/differentiation methodologies, using pluripotent and neural stem cells for transplantation and endogenous repair, the use of patient derived stem cells for disease modeling, using stem cells for drug discovery as well as the ethical issues related to the use of stem cells.



Stem Cells In Neurodegeneration Disease Modeling And Therapeutics


Stem Cells In Neurodegeneration Disease Modeling And Therapeutics
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Author : Kim A. Staats
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-17

Stem Cells In Neurodegeneration Disease Modeling And Therapeutics written by Kim A. Staats and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-17 with Science categories.