Stress Challenges And Immunity In Space
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Stress Challenges And Immunity In Space
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Author : Alexander Chouker
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-20
Stress Challenges And Immunity In Space written by Alexander Chouker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-20 with Medical categories.
Stress of either psychological or physical nature can activate and/or paralyse humans’ innate and adaptive immunity. However, adequate immunity is crucial to the maintenance of health on earth and in space. During space flight, human physiology and health are challenged by complex environmental stressors which might be at their most pronounced during lunar or interplanetary missions. While previous publications have addressed the physiological changes that occur during space flight, this book goes further, by adopting an interdisciplinary approach to analyze the complex interaction of living conditions in space, the immune system, and astronauts’ health. It is explained how such analysis of the consequences of stress for the immune system may help in preventing, diagnosing, and counteracting immune-related alterations in health on earth as well as in space
Stress Challenges And Immunity In Space
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Author : Alexander Choukèr
language : en
Publisher: Springer Nature
Release Date : 2019-11-27
Stress Challenges And Immunity In Space written by Alexander Choukèr and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-27 with Medical categories.
This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Into Space
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Author : Thais Russomano
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-05-30
Into Space written by Thais Russomano and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-30 with Technology & Engineering categories.
Our anatomy and physiology have been completely shaped by Earth's gravity. All body systems function in synergy with this unseen force. Yet, as we journey further and longer into space, our bodies must conform to a new reality, wherein gravity is absent or reduced, cosmic radiation threatens and our social and familial connections become distant. Into Space: A Journey of How Humans Adapt and Live in Microgravity gives an overview of some of the physiological, anatomical and cellular changes that occur in space and their effects on different body systems, such as the cardiovascular and musculoskeletal, and touches on cultural and psychosocial aspects of leaving behind family and the safety of Earth. It further addresses the complexity of manned space flights, showing how interdisciplinary this subject is and discussing the challenges that space physiologists, physicians and scientists must face as humans seek to conquer the final frontier.
Human Health And Performance Risks Of Space Exploration Missions
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Author : Jancy C. McPhee
language : en
Publisher: U. S. National Aeronautics & Space Administration
Release Date : 2009
Human Health And Performance Risks Of Space Exploration Missions written by Jancy C. McPhee and has been published by U. S. National Aeronautics & Space Administration this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Biography & Autobiography categories.
Introduction To Psychoneuroimmunology
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Author : Jorge H. Daruna
language : en
Publisher: Academic Press
Release Date : 2012-02-24
Introduction To Psychoneuroimmunology written by Jorge H. Daruna and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-24 with Medical categories.
Health is maintained by the coordinated operation of all the biological systems that make up the individual. The Introduction to Psychoneuroimmunology, Second Edition, presents an overview of what has been discovered by scientists regarding how bodily systems respond to environmental challenges and intercommunicate to sustain health. The book touches on the main findings from the current literature without being overly technical and complex. The result is a comprehensive overview of psychoneuroimmunology, which avoids oversimplification, but does not overwhelm the reader. Single authored for consistency of breadth and depth, with no redundancy of coverage between chapters Covers endocrine-immune modulation, neuro-immune modulation, and the enhancing or inhibiting processes of one or more systems on the others Expanded use of figures, tables, and text boxes
The Immune System In Space Are We Prepared
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Author : Alexander Choukèr
language : en
Publisher: Springer
Release Date : 2016-10-21
The Immune System In Space Are We Prepared written by Alexander Choukèr and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-21 with Medical categories.
This book gives insight into the mechanism of the immune system and the influence of the environment on earth. Further, the book explains the changes that occur in our immune system in the absence of gravity and their fundamental consequences. Several limiting factors for human health and performance in microgravity have been clearly identified as an unacceptable risk for long-term and interplanetary flights. Serious concerns arose whether spaceflight-associated immune system dysfunction ultimately precludes the expansion of human presence beyond Earth's orbit. The immune system has undergone many evolutionary steps to cope with a new and changing environment, but `space` has not been evolutionary experienced before. Through endocrine orchestration of cell functions, cell to cell communications and intracellular mechanisms the human body and his immune system have an enormous capacity to adapt and react to altered environmental conditions. Thus, the special sensitivity to altered gravity renders the immune system an ideal biological model system to understand if and how gravity on Earth is required for the normal function of cells and cellular networks. It is one of the most fundamental challenges to find out, if our organism and our cellular machinery are able to live and to adequately perform without the gravity field of Earth. The book is written for immunologists and researchers in human physiology under normal and stressfull conditions.
Safe Passage
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-11-20
Safe Passage written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-20 with Science categories.
Safe Passage: Astronaut Care for Exploration Missions sets forth a vision for space medicine as it applies to deep space voyage. As space missions increase in duration from months to years and extend well beyond Earth's orbit, so will the attendant risks of working in these extreme and isolated environmental conditions. Hazards to astronaut health range from greater radiation exposure and loss of bone and muscle density to intensified psychological stress from living with others in a confined space. Going beyond the body of biomedical research, the report examines existing space medicine clinical and behavioral research and health care data and the policies attendant to them. It describes why not enough is known today about the dangers of prolonged travel to enable humans to venture into deep space in a safe and sane manner. The report makes a number of recommendations concerning NASA's structure for clinical and behavioral research, on the need for a comprehensive astronaut health care system and on an approach to communicating health and safety risks to astronauts, their families, and the public.
Breakthroughs In Space Life Science Research
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Author : Günter Ruyters
language : en
Publisher: Springer Nature
Release Date : 2021-06-10
Breakthroughs In Space Life Science Research written by Günter Ruyters and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-10 with Medical categories.
This last volume of the SpringerBriefs in Space Life Sciences series is setup in 5 main parts. The 1st part shortly summarizes the history of life science research in space from the late 40s until today with focus on Europe and Germany, followed by a part on describing flight opportunities including the Space Shuttle/Spacelab system and the International Space Station ISS; in the 3rd part it focuses on extraordinary success stories of this constantly challenging research program and highlights some important key findings in space life science research. The book introduces in the 4th part innovative developments in non-invasive biomedical diagnostics and training methods for astronauts that emerge from this program and are of benefit for people on Earth especially in the aging society. Last but not least in its 5th part it closes with an outlook on the future of space life sciences in the upcoming era of space exploration. The book is intended for students and research scientists in the life sciences and biomedicine as well as for interested lay persons, who wish to get an overview of space life science research: its ́ early days, current status and future directions.
Effect Of Spaceflight And Spaceflight Analogue Culture On Human And Microbial Cells
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Author : Cheryl A. Nickerson
language : en
Publisher: Springer
Release Date : 2016-05-21
Effect Of Spaceflight And Spaceflight Analogue Culture On Human And Microbial Cells written by Cheryl A. Nickerson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-21 with Medical categories.
Many breakthroughs in biological research and translational healthcare advancements have been achieved by studying the response of biological systems to extreme environments. The spaceflight platform provides a unique environment where researchers can explore fundamental questions into cellular and molecular response mechanisms to unveil novel insight into human health and disease. Since the physical force of gravity has shaped the architecture of all biological systems on our planet, spaceflight provides the opportunity to see life in a new adaptational mode - in response to reduced gravity. This enables investigations into the effects of the microgravity environment and associated changes in mechanical forces on mammalian cells/tissues and microbial pathogens, to bring novel insight into disease mechanisms, which are not discernable using conventional experimental approaches. Research using spaceflight platforms represents a paradigm shift in how we observe life processes and is on the leading edge of research discoveries into cellular and molecular mechanisms of health and disease. By incorporating the views of leading authors, this book highlights landmark discoveries and advances in mammalian cellular and microbiology research in both true spaceflight and ground-based spaceflight analogue environments for scientists and students alike who are interested in the influence of physical forces on mammalian and microbial cells, how this impacts transition between normal homeostasis and disease, and basic mechanisms of adaptation to low gravity environments. To provide a thorough understanding of this research, this book covers a range of topics including: (i) description the physical forces interacting with cells in microgravity and microgravity analogue environments, (ii) how alterations in these cellular forces impact human physiology, specifically immune function, (iii) use of these environments to develop organotypic three-dimensional (3-D) tissue culture models as predictive human surrogates for organogenesis and disease research, and (iv) microbial pathogen responses to culture in these environments, focusing on infectious disease Collectively, this information reflects a critical step in preparation for long-duration human space exploration, advances our knowledge of basic biological processes and mechanisms important to understand normal function and disease, and may lead to new strategies for treatment and prevention.
Stress And Health
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Author : William R. Lovallo
language : en
Publisher: SAGE Publications
Release Date : 2015-01-29
Stress And Health written by William R. Lovallo and has been published by SAGE Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-29 with Psychology categories.
Stress and Health: Biological and Psychological Interactions is a brief and accessible examination of psychological stress and its psychophysiological relationships with cognition, emotions, brain functions, and the peripheral mechanisms by which the body is regulated. Updated throughout, the Third Edition covers two new and significant areas of emerging research: how our early life experiences alter key stress responsive systems at the level of gene expression; and what large, normal, and small stress responses may mean for our overall health and well-being.