Structural And Computational Glycobiology Immunity And Infection
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Structural And Computational Glycobiology Immunity And Infection
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Author : Elizabeth Yuriev
language : en
Publisher: Frontiers Media SA
Release Date : 2015-08-04
Structural And Computational Glycobiology Immunity And Infection written by Elizabeth Yuriev and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-04 with Immunologic diseases. Allergy categories.
Interest in understanding the biological role of carbohydrates has increased significantly over the last 20 years. The use of structural techniques to understand carbohydrate-protein recognition is still a relatively young area, but one that is of emerging importance. The high flexibility of carbohydrates significantly complicates the determination of high quality structures of their complexes with proteins. Specialized techniques are often required to understand the complexity of carbohydrate recognition by proteins. In this Research Topic, we will focus on structural and computational approaches to understanding carbohydrate recognition by proteins involved in immunity and infection. Particular areas of focus include cancer immunotherapeutics, carbohydrate-lectin interactions, glycosylation and glycosyltransferases.
Translational Glycobiology In Human Health And Disease
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Author : Michelle Kilcoyne
language : en
Publisher: Academic Press
Release Date : 2023-11-29
Translational Glycobiology In Human Health And Disease written by Michelle Kilcoyne and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-29 with Science categories.
Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment.Translational Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences.Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery. Provides a deep, foundational overview of glycoscience and its translational potential, highlighting glycobiology’s growing role in human health and disease study Examines a broad range of relevant disease areas and applications of glycobiology in policy and public health Features chapter contributions from leading, international experts in the field, fully integrating perspectives from the health, computational, materials, biopharmaceutical, and diagnostic sciences
Structural Glycobiology
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Author : Elizabeth Yuriev
language : en
Publisher: CRC Press
Release Date : 2012-09-27
Structural Glycobiology written by Elizabeth Yuriev and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-27 with Medical categories.
Structural Glycobiology covers the experimental, theoretical, and alternative technologies used in the study of the structural basis for the diverse biological roles of carbohydrates. The book overviews the application of specialized technologies to the study of carbohydrates in biology, reviews relevant and current research in the field, and is illustrated throughout by specific examples of how research investigations have yielded key structural and associated biological data on carbohydrates and glycolipids. In particular, the book focuses on: X-ray crystallography and small-angle scattering, NMR, and cryo-electron microscopy techniques Theoretical (modeling-based) approaches, such as molecular mechanics, molecular dynamics, free energy calculations, and carbohydrate docking Alternative techniques for yielding structural information on carbohydrates from complex biological samples Carbohydrates in medicine, specifically in areas that have been directly impacted by our understanding of the structural role of carbohydrates in immune recognition: cancer, organ transplantation, and infection
Odyssey Of Surfactant Proteins Sp A And Sp D Innate Immune Surveillance Molecules
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Author : Uday Kishore
language : en
Publisher: Frontiers Media SA
Release Date : 2020-05-05
Odyssey Of Surfactant Proteins Sp A And Sp D Innate Immune Surveillance Molecules written by Uday Kishore and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-05 with categories.
The Viral Evasion Of Antiviral Innate Immunity
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Author : Chunfu Zheng
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-01
The Viral Evasion Of Antiviral Innate Immunity written by Chunfu Zheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-01 with Science categories.
Glycoimmunology
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Author : Azita Alavi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Glycoimmunology written by Azita Alavi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Proceedings of the Third Jenner International Glycoimmunology meeting held in Il Ciocco, Tuscany, Italy, October 11-14, 1994
Computational Immunology
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Author : Shyamasree Ghosh
language : en
Publisher: CRC Press
Release Date : 2019-10-14
Computational Immunology written by Shyamasree Ghosh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-14 with Medical categories.
The immune system is highly complex system with large number of macromolecules, signaling pathways, protein-protein interactions, and gene expressions. Studies from genomics, transcriptomics, metabolomics are generating huge high throughput data that needs to be analyzed for understanding the Immune system in Health and Disease. Computational approaches arehelping in understanding the study of complex biology of immunology and thereby enabling design of therapeutic strategies in diseases like infectious diseases, immunodeficiency, allergic, hypersensitive, autoimmune disorders and diseases like Cancer, HIV etc. Computational Immunology: Basics highlights the basics of the immune system and function in health and disease. This book offers comprehensive coverage of the most essential topics, including Overview of Immunology and computational Immunology Immune organs and cells, antigen, antibody, B, cell, T cell Antigen Processing and presentation Diseases due to abnormalities of the immune system Cancer Biology Shyamasree Ghosh (MSc, PhD, PGDHE, PGDBI), is currently working in the School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhubaneswar, DAE, Govt of India, graduated from the prestigious Presidency College Kolkata in 1998. She was awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.
The Role Of Glycans In Infectious Disease
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Author : Ivan Martinez Duncker
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-02
The Role Of Glycans In Infectious Disease written by Ivan Martinez Duncker and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-02 with Science categories.
Glycobiology And Human Diseases
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Author : Gherman Wiederschain
language : en
Publisher: CRC Press
Release Date : 2016-02-22
Glycobiology And Human Diseases written by Gherman Wiederschain and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-22 with Medical categories.
This book discusses glycobiology and various forms of human diseases. Topics covered include immunoglobulins, inflammation and glycosylation, the role and therapeutic significance of natural anti-glycan antibodies in malignancies and in normal and aberrant pregnancy, identifying urinary glycans as a possible method for the diagnosis of lysosomal st
Glycobiology Of Innate Immunology
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Author : Cheorl-Ho Kim
language : en
Publisher: Springer Nature
Release Date : 2022-03-31
Glycobiology Of Innate Immunology written by Cheorl-Ho Kim and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Science categories.
This book presents the latest knowledge and the most recent research results on glycobiology of innate immunology. Innate immunity is the crucial part of the immunological defense system that exerts their distinct functions through binding to certain functional glycoproteins. They play a role in various human diseases and also function against microbial invaders and self-associated molecular patterns. Co-regulated expression of glycan-binding is associated with many biological components such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell–cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein–carbohydrate or carbohydrate–carbohydrate interactions. This book opens by providing the key background on glycans in innate immunity and its mechanisms behind the Dendritic cell interactions during infection and inflammation are examined in depth, and the concluding chapter is devoted to signaling tumor immunotherapy. Up-to-date information is then presented on all aspects of glycan structure-recognizing signaling. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.