Structural Genomics Part B
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Structural Genomics Part B
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Author : Andrzej Joachimiak
language : en
Publisher: Academic Press
Release Date : 2009-11-26
Structural Genomics Part B written by Andrzej Joachimiak and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-26 with Science categories.
Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale. - Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy - Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission
Structural Genomics Part B
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Author : Andrzej Joachimiak
language : en
Publisher: Academic Press
Release Date : 2009-12-09
Structural Genomics Part B written by Andrzej Joachimiak and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-09 with Science categories.
Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.
Structural Genomics Part A
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Author : Andrzej Joachimiak
language : en
Publisher: Academic Press
Release Date : 2011-09-02
Structural Genomics Part A written by Andrzej Joachimiak and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-02 with Science categories.
Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale. - Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy - Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission
Structural Genomics Part C
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-11-26
Structural Genomics Part C written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-26 with Science categories.
Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale. - Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy - Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission
Structural Genomics
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Author : Andrzej Joachimiak
language : en
Publisher:
Release Date : 2008
Structural Genomics written by Andrzej Joachimiak and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Genomics categories.
Nuclear Magnetic Resonance
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Author : Jacek Wojcik
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013-05-24
Nuclear Magnetic Resonance written by Jacek Wojcik and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Science categories.
With over 17,000 articles concerning NMR published per year, keeping up to date with the latest developments and applications of this technique can prove time-consuming. Now in its 42nd volume, the Specialist Periodical Report on NMR provides a digest of the current literature, compiled by experts in the field. The current volume devotes several chapters to the aspects and applications of spin-spin couplings, and biochemists will find seperate chapters dedicated to proteins, lipids and carbohydrates. Further chapters discuss the latest developments in nuclear sheilding, imaging and NMR in living systems. For a comprehensive account of the latest developments and research using NMR, look no further than Specialist Periodical Reports - Nuclear Magnetic Resonance. An essential book for NMR lab and university shelf.
Nuclear Magnetic Resonance
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Author : Jacek Wojcik
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013-03-21
Nuclear Magnetic Resonance written by Jacek Wojcik and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-21 with Medical categories.
Applications of Nuclear Magnetic Resonance (NMR) span a wide range of scientific disciplines, including physis, biology and medicine. Each volume in this series comprises a combination of reports offering a comprehensive coverage of the literature. With an unrivalled scope of coverage, this Specialist Periodical Report presents an invaluable source of current methods and applications for seasoned practitioners and newcomers alike.
Fragment Based Drug Design
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Author :
language : en
Publisher: Academic Press
Release Date : 2011-02-28
Fragment Based Drug Design written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-28 with Medical categories.
There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits. - Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens - The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD
Bioinformatics And Functional Genomics
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Author : Jonathan Pevsner
language : en
Publisher: John Wiley & Sons
Release Date : 2005-03-04
Bioinformatics And Functional Genomics written by Jonathan Pevsner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-03-04 with Science categories.
Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.
Index Medicus
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Author :
language : en
Publisher:
Release Date : 2004
Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.