Structure Function And Genetics Of Ribosomes
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Structure Function And Genetics Of Ribosomes
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Author : Boyd Hardesty
language : en
Publisher: Springer
Release Date : 1986-10-14
Structure Function And Genetics Of Ribosomes written by Boyd Hardesty and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-10-14 with Science categories.
During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramati cally different. We have an almost bewildering variety of information de tailing many different aspects of life at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for replicating, distributing, and modifying biological information. We have learned a great deal about the chemical and physical nature of the macromolecular nucleic acids and proteins, and the manner in which carbohydrates, lipids, and smaller mole cules work together to provide the molecular setting of living systems. It might be said that these few decades have replaced a near vacuum of information with a very large surplus. It is in the context of this flood of information that this series of mono graphs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field.
Ribosomes Structure Function And Genetics
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Author : Glenn Chambliss
language : en
Publisher:
Release Date : 1980
Ribosomes Structure Function And Genetics written by Glenn Chambliss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Science categories.
Ribosomes Structure Function And Dynamics
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Author : Marina V. Rodnina
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-10
Ribosomes Structure Function And Dynamics written by Marina V. Rodnina and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-10 with Medical categories.
The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering all facets of the structure and function of the ribosome. New high-resolution crystal structures of functional ribosome complexes and cryo-EM structures of translating ribosomes are presented, while partial reactions of translation are examined in structural and mechanistic detail, featuring translocation as a most dynamic process. Mechanisms of initiation, both in bacterial and eukaryotic systems, translation termination, and novel details of the functions of the respective factors are described. Structure and interactions of the nascent peptide within, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a source of essential information for years to come.
The Ribosome
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Author : Walter Ensign Hill
language : en
Publisher: ASM Press
Release Date : 1990
The Ribosome written by Walter Ensign Hill and has been published by ASM Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Science categories.
This book is recommended as a 'hitchhiker's guide to the ribosome' for everyone with an interest in translation, RNA-protein structures, and macromolecular structure-function relationships Science >.
Ribosomes Structure Function And Genetics
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Author : Glenn Chambliss
language : en
Publisher:
Release Date : 1980
Ribosomes Structure Function And Genetics written by Glenn Chambliss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with categories.
Protein Synthesis And Ribosome Structure
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Author : Knud H. Nierhaus
language : en
Publisher: John Wiley & Sons
Release Date : 2009-07-10
Protein Synthesis And Ribosome Structure written by Knud H. Nierhaus and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-10 with Science categories.
Knud Nierhaus, who has studied the ribosome for more than 30 years, has assembled here the combined efforts of several scientific disciplines into a uniform picture of the largest enzyme complex found in living cells, finally resolving many decades-old questions in molecular biology. In so doing he considers virtually all aspects of ribosome structure and function -- from the molecular mechanism of different ribosomal ribozyme activities to their selective inhibition by antibiotics, from assembly of the core particle to the regulation of ribosome component synthesis. The result is a premier resource for anyone with an interest in ribosomal protein synthesis, whether in the context of molecular biology, biotechnology, pharmacology or molecular medicine.
Ribosomes
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Author : Alexander Spirin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Ribosomes written by Alexander Spirin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
This book is based on an advanced course of lectures on ribosome structure and protein biosynthesis that I offer at the Moscow State University. These lectures have been part of a general course on molecular biology for almost three decades, and they have undergone considerable evolution as knowledge has been pro gressing in this field. The progress continues, and readers should be prepared that some facts, statements, and ideas included in the book may be incomplete or out of-date. In any case, this is primarily a textbook, but not a comprehensive review. It provides a background of knowledge and current ideas in the field and gives ex amples of observations and their interpretations. I understand that some interpre tations and generalizations may be tentative or disputable, but I hope that this will stimulate thinking and discussing better than if I left white spots. The book has a prototype: it is my monograph "Ribosome Structure and Pro tein Biosynthesis" published by the Benjamin/Cummings Publishing Company, Menlo Park, California, in 1986. Here I have basically kept the former order of pre sentation ofthe topics and the subdivision into chapters. The contents ofthe chap ters, however, have been significantly revised and supplemented. The newly writ ten chapters on translational control in prokaryotes (Chapter 16) and eukaryotes (Chapter 17) are added.
The Nucleolus
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Author : Mark O. J. Olson
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-08-03
The Nucleolus written by Mark O. J. Olson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-08-03 with Science categories.
As the first comprehensive overview of the nucleolus since 1985, The Nucleolus covers our current understanding of the cell nucleolus, including its role in ribosome assembly and its additional newly-discovered activities. The eighteen chapters have been written by experts who are actively engaged in research on the nucleolus and have an in depth review of the following topics: - nucleolar ultrastructure and dynamics, - behavior during mitosis, - ribosomal DNA gene and chromatin structure, - pre-ribosomal RNA transcription, - processing and modification, - ribosome assembly, - small nucleolar RNAs, - proteomics and non-traditional functions of the nucleolus. Separate chapters are also provided for yeast and higher eukaryotes on many topics. The Nucleolus will appeal not only to scientists directly engaged in nucleolar research, but also those working in related areas such as gene expression, protein biosynthesis, ribosome structure, transcription, chromatin structure, molecular genetics and the structure and functions of the cell nucleus in general.
Emerging Concepts In Ribosome Structure Biogenesis And Function
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Author : Vijay Kumar
language : en
Publisher: Academic Press
Release Date : 2021-09-25
Emerging Concepts In Ribosome Structure Biogenesis And Function written by Vijay Kumar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-25 with Science categories.
Ribosome biogenesis is the process of making ribosomes which are responsible for mRNA translation into proteins. It is a tightly regulated process closely linked to nearly all biochemical and cellular processes, including cell division, growth, and development. Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides a synthesized overview of all the parts engaged in this process. The book begins by providing an introduction to the ribosome factory, its origin, and its evolution of translation. It then goes on to describe ribosome structure including subunits, RNA, and protein components. Ribosome biogenesis and its emergence as a frontier research area for translational potential in cancer and other diseases are also discussed. In addition, the book explores current developments in ribosome research like the emergence of ribosomopathies, how deregulation of ribosome biogenesis can impact disease mechanisms and aging, and the discovery of specialized ribosomes that have specific functions that may translate differentially with consequences on normal and pathological processes. Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides fundamental coverage and emerging research on ribosomes, biogenesis, and their structure and function and is a resourceful introduction for new researchers and those engaged in interdisciplinary ribosomal research. Provides an overview of ribosome biogenesis and examines its involvement in cell transformation and cancerous growth Covers disorders related to the ribosome (ribosomopathies) and explains the significance of ribosome dysfunction in human diseases Includes commonly used methods to study ribosomes, such as polysome preparation, RNA profiling and proteomics, CryoEM, and Cell-free assays along with proper illustrations
Ribosomes
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Author : Zhou Lin
language : en
Publisher: Nova Science Publishers
Release Date : 2013
Ribosomes written by Zhou Lin and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Ribosomes categories.
Ribosomes are essential protein-RNA complexes that synthesize proteins according to the gene library of the cell in all living organisms. In this book, the authors present current research in the study of the molecular structure, biological functions and implications for genetic disease of ribosomes. Topics include ribosomal alterations and immune-related illness; the role of ribosomes in mediating hypoxia response and tolerance in eukaryotes; the potential biomedical use of ribosome-inactivating proteins; coarse-graining the nano-machine ribosome to elucidate its functional dynamics; and structural aspects of ribosomal ligands interactions providing the work of the human translational machinery.