Study Design And Statistical Analysis
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Study Design And Statistical Analysis
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Author : Mitchell Katz
language : en
Publisher: Cambridge University Press
Release Date : 2006-06-22
Study Design And Statistical Analysis written by Mitchell Katz and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-22 with Medical categories.
This book takes the reader through the entire research process: choosing a question, designing a study, collecting the data, using univariate, bivariate and multivariable analysis, and publishing the results. It does so by using plain language rather than complex derivations and mathematical formulae. It focuses on the nuts and bolts of performing research by asking and answering the most basic questions about doing research studies. Making good use of numerous tables, graphs and tips, this book helps to demystify the process. A generous number of up-to-date examples from the clinical literature give an illustrated and practical account of how to use multivariable analysis.
Research Design Statistical Analysis
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Author : Arnold D. Well
language : en
Publisher: Psychology Press
Release Date : 2003-01-30
Research Design Statistical Analysis written by Arnold D. Well and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-30 with Mathematics categories.
"Free CD contains several real and artificial data sets used in the book in SPSS, SYSTAT, and ASCII formats"--Cover
Research Design Statistical Analysis
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Author : Arnold D. Well
language : en
Publisher: Psychology Press
Release Date : 2003-01-30
Research Design Statistical Analysis written by Arnold D. Well and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-30 with Psychology categories.
This book emphasizes the statistical concepts and assumptions necessary to describe and make inferences about real data. Throughout the book the authors encourage the reader to plot and examine their data, find confidence intervals, use power analyses to determine sample size, and calculate effect sizes. The goal is to ensure the reader understands the underlying logic and assumptions of the analysis and what it tells them, the limitations of the analysis, and the possible consequences of violating assumptions. The simpler, less abstract discussion of analysis of variance is presented prior to developing the more general model. A concern for alternatives to standard analyses allows for the integration of non-parametric techniques into relevant design chapters, rather than in a single, isolated chapter. This organization allows for the comparison of the pros and cons of alternative procedures within the research context to which they apply. Basic concepts, such as sampling distributions, expected mean squares, design efficiency, and statistical models are emphasized throughout. This approach provides a stronger conceptual foundation in order to help the reader generalize the concepts to new situations they will encounter in their research and to better understand the advice of statistical consultants and the content of articles using statistical methodology. The second edition features a greater emphasis on graphics, confidence intervals, measures of effect size, power analysis, tests of contrasts, elementary probability, correlation, and regression. A Free CD that contains several real and artificial data sets used in the book in SPSS, SYSTAT, and ASCII formats, is included in the back of the book. An Instructor's Solutions Manual, containing the intermediate steps to all of the text exercises, is available free to adopters.
Understanding Statistics And Experimental Design
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Author : Michael H. Herzog
language : en
Publisher: Springer
Release Date : 2019-08-13
Understanding Statistics And Experimental Design written by Michael H. Herzog and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-13 with Science categories.
This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. Part I makes key concepts in statistics readily clear. Parts I and II give an overview of the most common tests (t-test, ANOVA, correlations) and work out their statistical principles. Part III provides insight into meta-statistics (statistics of statistics) and demonstrates why experiments often do not replicate. Finally, the textbook shows how complex statistics can be avoided by using clever experimental design. Both non-scientists and students in Biology, Biomedicine and Engineering will benefit from the book by learning the statistical basis of scientific claims and by discovering ways to evaluate the quality of scientific reports in academic journals and news outlets.
Small Clinical Trials
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-02-01
Small Clinical Trials written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-02-01 with Medical categories.
Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.
Design And Analysis In Educational Research
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Author : Kamden K. Strunk
language : en
Publisher: Routledge
Release Date : 2020-04-02
Design And Analysis In Educational Research written by Kamden K. Strunk and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-02 with Education categories.
NEW: updated eResources, 'Case Studies for Teaching on Race, Racism and Black Lives Matter.' Please see Support Material tab to download the new resources. This book presents an integrated approach to learning about research design alongside statistical analysis concepts. Strunk and Mwavita maintain a focus on applied educational research throughout the text, with practical tips and advice on how to do high-quality quantitative research. Design and Analysis in Educational Research teaches research design (including epistemology, research ethics, forming research questions, quantitative design, sampling methodologies, and design assumptions) and introductory statistical concepts (including descriptive statistics, probability theory, sampling distributions), basic statistical tests (like z and t), and ANOVA designs, including more advanced designs like the factorial ANOVA and mixed ANOVA, using SPSS for analysis. Designed specifically for an introductory graduate course in research design and statistical analysis, the book takes students through principles by presenting case studies, describing the research design principles at play in each study, and then asking students to walk through the process of analyzing data that reproduce the published results. An online eResource is also available with data sets. This textbook is tailor-made for first-level doctoral courses in research design and analysis, and will also be of interest to graduate students in education and educational research.
Study Design And Statistical Analysis
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Author : Mitchell Katz
language : en
Publisher: Cambridge University Press
Release Date : 2006-06-22
Study Design And Statistical Analysis written by Mitchell Katz and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-22 with Medical categories.
A nuts-and-bolts guide to research by asking and answering the most basic questions about doing research studies.
Sequential Experimentation In Clinical Trials
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Author : Jay Bartroff
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-12
Sequential Experimentation In Clinical Trials written by Jay Bartroff and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-12 with Medical categories.
Sequential Experimentation in Clinical Trials: Design and Analysis is developed from decades of work in research groups, statistical pedagogy, and workshop participation. Different parts of the book can be used for short courses on clinical trials, translational medical research, and sequential experimentation. The authors have successfully used the book to teach innovative clinical trial designs and statistical methods for Statistics Ph.D. students at Stanford University. There are additional online supplements for the book that include chapter-specific exercises and information. Sequential Experimentation in Clinical Trials: Design and Analysis covers the much broader subject of sequential experimentation that includes group sequential and adaptive designs of Phase II and III clinical trials, which have attracted much attention in the past three decades. In particular, the broad scope of design and analysis problems in sequential experimentation clearly requires a wide range of statistical methods and models from nonlinear regression analysis, experimental design, dynamic programming, survival analysis, resampling, and likelihood and Bayesian inference. The background material in these building blocks is summarized in Chapter 2 and Chapter 3 and certain sections in Chapter 6 and Chapter 7. Besides group sequential tests and adaptive designs, the book also introduces sequential change-point detection methods in Chapter 5 in connection with pharmacovigilance and public health surveillance. Together with dynamic programming and approximate dynamic programming in Chapter 3, the book therefore covers all basic topics for a graduate course in sequential analysis designs.
Design Of Experiments And Advanced Statistical Techniques In Clinical Research
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Author : Basavarajaiah D. M.
language : en
Publisher: Springer Nature
Release Date : 2020-11-05
Design Of Experiments And Advanced Statistical Techniques In Clinical Research written by Basavarajaiah D. M. and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-05 with Medical categories.
Recent Statistical techniques are one of the basal evidence for clinical research, a pivotal in handling new clinical research and in evaluating and applying prior research. This book explores various choices of statistical tools and mechanisms, analyses of the associations among different clinical attributes. It uses advanced statistical methods to describe real clinical data sets, when the clinical processes being examined are still in the process. This book also discusses distinct methods for building predictive and probability distribution models in clinical situations and ways to assess the stability of these models and other quantitative conclusions drawn by realistic experimental data sets. Design of experiments and recent posthoc tests have been used in comparing treatment effects and precision of the experimentation. This book also facilitates clinicians towards understanding statistics and enabling them to follow and evaluate the real empirical studies (formulation of randomized control trial) that pledge insight evidence base for clinical practices. This book will be a useful resource for clinicians, postgraduates scholars in medicines, clinical research beginners and academicians to nurture high-level statistical tools with extensive scope.
Epidemiology
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Author : Mark Woodward
language : en
Publisher: CRC Press
Release Date : 2013-12-19
Epidemiology written by Mark Woodward and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-19 with Mathematics categories.
Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet