Superbug Evolution
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Superbug Evolution
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Author : Ursula Brightonstar
language : en
Publisher: Publifye AS
Release Date : 2025-02-27
Superbug Evolution written by Ursula Brightonstar and has been published by Publifye AS this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-27 with Medical categories.
Superbug Evolution explores the escalating crisis of antimicrobial resistance, focusing on multidrug-resistant organisms and their impact on global healthcare. It examines the evolutionary mechanisms driving antibiotic resistance, revealing how widespread antibiotic use in medicine and agriculture inadvertently fosters the development of superbugs. The book highlights that superbug emergence is not just a medical issue but a complex ecological and evolutionary challenge shaped by human actions. The book begins with a historical overview of antibiotic use and the subsequent rise of resistance. It then progresses to detail the genetic mechanisms bacteria use to evade antimicrobials and analyzes the ecological factors influencing superbug spread in various environments. Later chapters address clinical implications, offering strategies for infection control and advocating for a One Health approach, recognizing the interconnectedness of human, animal, and environmental health. This book uniquely integrates evolutionary principles into the analysis of antimicrobial resistance, moving beyond a purely medical perspective. Drawing from scientific literature and epidemiological data, it presents a thorough exploration of this pressing global health issue, making complex concepts accessible to a broad audience. It emphasizes the need for interdisciplinary collaboration to combat this threat.
Superbug
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Author : Maryn McKenna
language : en
Publisher: Simon and Schuster
Release Date : 2010-03-23
Superbug written by Maryn McKenna and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-23 with Medical categories.
LURKING in our homes, hospitals, schools, and farms is a terrifying pathogen that is evolving faster than the medical community can track it or drug developers can create antibiotics to quell it. That pathogen is MRSA—methicillin-resistant Staphyloccocus aureus—and Superbug is the first book to tell the story of its shocking spread and the alarming danger it poses to us all. Doctors long thought that MRSA was confined to hospitals and clinics, infecting almost exclusively those who were either already ill or old. But through remarkable reporting, including hundreds of interviews with the leading researchers and doctors tracking the deadly bacterium, acclaimed science journalist Maryn McKenna reveals the hidden history of MRSA’s relentless advance—how it has overwhelmed hospitals, assaulted families, and infiltrated agriculture and livestock, moving inexorably into the food chain. Taking readers into the medical centers where frustrated physicians must discard drug after drug as they struggle to keep patients alive, she discloses an explosion of cases that demonstrate how MRSA is growing more virulent, while evolving resistance to antibiotics with astonishing speed. It may infect us at any time, no matter how healthy we are; it is carried by a stunning number of our household pets; and it has been detected in food animals from cows to chickens to pigs. With the sensitivity of a novelist, McKenna portrays the emotional and financial devastation endured by MRSA’s victims, vividly describing the many stealthy ways in which the pathogen overtakes the body and the shock and grief of parents whose healthy children were felled by infection in just hours. Through dogged detective work, she discloses the unheard warnings that predicted the current crisis and lays bare the flaws that have allowed MRSA to rage out of control: misplaced government spending, inadequate public health surveillance, misguided agricultural practices, and vast overuse of the few precious drugs we have left. Empowering readers with the knowledge they need for self-defense, Superbug sounds an alarm: MRSA has evolved into a global emergency that touches almost every aspect of modern life. It is, as one deeply concerned researcher tells McKenna, "the biggest thing since AIDS."
Pseudomonas Aeruginosa The Superbug
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Author : Silpi Basak
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2022-07-12
Pseudomonas Aeruginosa The Superbug written by Silpi Basak and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-12 with Medical categories.
Pseudomonas aeruginosa is one of the most commonly isolated bacterial species in clinical microbiology laboratories and it causes infections in hospitalized patients with strains resistant to many antimicrobials. In addition, it can form a biofilm especially in cystic fibrosis patients and patients with medical devices. Extracellular polymeric substances (EPS) or extracellular matrixes in biofilm prevent access of antimicrobial agents, disinfectants, and host-produced immune responses. Antimicrobial resistance in Pseudomonas aeruginosa is multifactorial and can be due to mutation, transfer of genes by plasmids, or transposons, among other causes. Production of β-lactamases causes resistance to β-lactam drugs including Carbapenems. Against this background of emergence of antibiotic resistance, this book studies different types of β-lactamases routinely produced by Pseudomonas aeruginosa strains in clinical microbiology laboratories. It shows that, although molecular methods like Polymerase Chain Reaction (PCR) are the gold standard for detection of different types of β-lactamases, they are very costly and require expertise.
Streptococcus Pneumoniae
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Author : Jeremy Brown
language : en
Publisher: Academic Press
Release Date : 2015-05-08
Streptococcus Pneumoniae written by Jeremy Brown and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-08 with Science categories.
Streptococcus Pneumoniae: Molecular Mechanisms of Host-Pathogen Interactions provides a comprehensive overview of our existing knowledge on Streptococcus pneumoniae antibiotic resistance, dissemination, and pathogenesis, including immunology. It presents a state-of-the-art overview of the implications of existing data, along with the areas of research that are important for future insights into the molecular mechanisms of pneumococcal infections and how to combat these infections. Users will find a timely update on the topic, as the dramatic increase in antibiotic resistance pneumoniae cases and limitations of the currently available pneumoniae vaccines are creating new concerns on these gram-positive bacteria that are endowed with a high virulence potential, and are the most common etiologic agent of respiratory and life-threatening invasive diseases. - Provides an updated overview of our existing knowledge on Streptococcus pneumoniae antibiotic resistance, dissemination, and pathogenesis, including immunology - Helps strengthen interdisciplinary networking and the focus of scientific resources by targeting epidemiology, vaccines, genetics, antibiotic resistance, clonal dissemination, Streptococcus pneumoniae biology, functional genomics, inflammasome, biomarkers, and more - Multi-authored by leaders in the field who present a state-of-the-art overview of what the implications are of existing data, and the areas of research that are important for future insights into the molecular mechanisms of pneumococcal infections - Supports combinatory networking in order to find new solutions in clinical therapies - Reflects the most topical pneumococcal research trends
Drug Resistance In Bacteria Fungi Malaria And Cancer
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Author : Gunjan Arora
language : en
Publisher: Springer
Release Date : 2017-03-21
Drug Resistance In Bacteria Fungi Malaria And Cancer written by Gunjan Arora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-21 with Medical categories.
This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.
Evolutionary Medicine
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Author : Edward P Bass Professor of Ecology and Evolutionary Biology Stephen C Stearns
language : en
Publisher: Oxford University Press
Release Date : 2024-07
Evolutionary Medicine written by Edward P Bass Professor of Ecology and Evolutionary Biology Stephen C Stearns and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07 with Medical categories.
With recent updates, the second edition of Evolutionary Medicine presents general principles of evolutionary biology and organismal design, then applies them to medical issues where these principles bring useful insights.
Evolution
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Author :
language : en
Publisher: PediaPress
Release Date :
Evolution written by and has been published by PediaPress this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Governance In The Age Of Gen Ai
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Author : Ashwin Rangan
language : en
Publisher: Archway Publishing
Release Date : 2025-05-28
Governance In The Age Of Gen Ai written by Ashwin Rangan and has been published by Archway Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-28 with Technology & Engineering categories.
Board members and management need to understand how generative AI impacts their business and the industry, and what strategic choices will enable them to exploit the opportunities and manage the challenges. In Governance in The Age of Gen AI, authors Ashwin Rangan and Dean A. Yoost present twelve vantage points on generative AI. Beginning with a discussion of the new foundation of artificial intelligence, market, and competitive analysis, and the technology and AI infrastructure requirements, the chapters move to the criticality of data governance, and hallucinations, prompt engineering, and retrieval-augmented generation. Rangan and Yoost then transition to the critical roles and skills development, managing the risks, and testing, evaluation, and measuring the success, as well as software development and system integration, creating the strategy, and the board’s governance in the age of AI. It closes with perspectives on what is likely to be next. The handbook serves as a guide for directors and management, offering a practical lens to the most important questions and emerging challenges with generative AI. In an easy-to-read and understandable format, it offers information about the fundamentals of AI, and it tells how to stimulate creative and critical thinking in the boardroom. The power of generative AI is just beginning to be recognized and valued. Board members and executives need to be fully informed to get their organizations on top of the wave.
Trends And Challenges Of Medical Education In The Changing Academic And Public Health Environment Of The 21st Century
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Author : Mainul Haque
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-20
Trends And Challenges Of Medical Education In The Changing Academic And Public Health Environment Of The 21st Century written by Mainul Haque and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-20 with Social Science categories.
Encyclopedia Of Evolution
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Author : Stanley A. Rice
language : en
Publisher: Infobase Publishing
Release Date : 2009
Encyclopedia Of Evolution written by Stanley A. Rice and has been published by Infobase Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Science categories.
Evolutionary science is not only one of the greatest breakthroughs of modern science, but also one of the most controversial. Perhaps more than any other scientific area, evolutionary science has caused us all to question what we are, where we came from, and how we relate to the rest of the universe. Encyclopedia of Evolution contains more than 200 entries that span modern evolutionary science and the history of its development. This comprehensive volume clarifies many common misconceptions about evolution. For example, many people have grown up being told that the fossil record does not demonstrate an evolutionary pattern, and that there are many missing links. In fact, most of these missing links have been found, and their modern representatives are often still alive today. The biographical entries represent evolutionary scientists within the United States who have had and continue to have a major impact on the broad outline of evolutionary science. The biographies chosen reflect the viewpoints of scientists working within the United States. Five essays that explore interesting questions resulting from studies in evolutionary science are included as well. The appendix consists of a summary of Charles Darwin's Origin of Species, which is widely considered to be the foundational work of evolutionary science and one of the most important books in human history. The five essays include: How much do genes control human behavior?What are the ghosts of evolution?Can an evolutionary scientist be religious?Why do humans die?Are humans alone in the universe