Surrogate Tissue Analysis
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Surrogate Tissue Analysis
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Author : Michael E. Burczynski
language : en
Publisher: CRC Press
Release Date : 2005-11-10
Surrogate Tissue Analysis written by Michael E. Burczynski and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-10 with Medical categories.
Both an introduction and a fundamental reference, this book explores how to apply genomic, proteomic, and metabolomic technologies to surrogate tissue analysis. It reviews fundamental analytical issues and actual initial results generated using these technologies. The book covers transcriptional profiling (genomics), protein profiling (proteomics), methylation profiling (epigenomics), metabolite profiling (metabolomics) and additional biomarker identification methods that can be applied to surrogate tissues. This book is useful to researchers and scientists interested in applying novel methodologies for identifying biomarkers in the fields of pharmacology, toxicology, and medicine.
Clinical Labor
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Author : Melinda Cooper
language : en
Publisher: Duke University Press
Release Date : 2014-01-22
Clinical Labor written by Melinda Cooper and has been published by Duke University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-22 with Social Science categories.
Forms of embodied labor, such as surrogacy and participation in clinical trials, are central to biomedical innovation, but they are rarely considered as labor. Melinda Cooper and Catherine Waldby take on that project, analyzing what they call "clinical labor," and asking what such an analysis might indicate about the organization of the bioeconomy and the broader organization of labor and value today. At the same time, they reflect on the challenges that clinical labor might pose to some of the founding assumptions of classical, Marxist, and post-Fordist theories of labor. Cooper and Waldby examine the rapidly expanding transnational labor markets surrounding assisted reproduction and experimental drug trials. As they discuss, the pharmaceutical industry demands ever greater numbers of trial subjects to meet its innovation imperatives. The assisted reproductive market grows as more and more households look to third-party providers for fertility services and sectors of the biomedical industry seek reproductive tissues rich in stem cells. Cooper and Waldby trace the historical conditions, political economy, and contemporary trajectory of clinical labor. Ultimately, they reveal clinical labor to be emblematic of labor in twenty-first-century neoliberal economies.
Evaluation Of Biomarkers And Surrogate Endpoints In Chronic Disease
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2010-06-25
Evaluation Of Biomarkers And Surrogate Endpoints In Chronic Disease written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-25 with Medical categories.
Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.
The Evaluation Of Surrogate Endpoints
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Author : Tomasz Burzykowski
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-11-24
The Evaluation Of Surrogate Endpoints written by Tomasz Burzykowski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-24 with Medical categories.
Covers the latest research on a sensitive and controversial topic in a professional and well researched manner. Provides practical outlook as well as model guidelines and software tools that should be of interest to people who use the software tools described and those who do not. Related title by Co-author Geert Molenbergh has sold more than 3500 copies world wide. Provides dual viewpoints: from scientists in the industry as well as regulatory authorities.
Qa Qc Guidance For Sampling And Analysis Of Sediments Water And Tissues For Dredged Material Evaluations Chemical Evaluations
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Author :
language : en
Publisher: DIANE Publishing
Release Date : 1995
Qa Qc Guidance For Sampling And Analysis Of Sediments Water And Tissues For Dredged Material Evaluations Chemical Evaluations written by and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Water quality biological assessment categories.
Biomarkers In Toxicology
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Author : Ramesh C. Gupta
language : en
Publisher: Academic Press
Release Date : 2014-01-25
Biomarkers In Toxicology written by Ramesh C. Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-25 with Medical categories.
Biomarkers in Toxicology is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This book includes both vertebrate and non-vertebrate species models for toxicological testing and development of biomarkers. Divided into several key sections, this reference volume contains chapters devoted to topics in molecular-cellular toxicology, as well as a look at the latest cutting-edge technologies used to detect biomarkers of exposure and effects. Each chapter also contains several references to the current literature and important resources for further reading. Given this comprehensive treatment, Biomarkers in Toxicology is an essential reference for all those interested in biomarkers across several scientific and biomedical fields. Written by international experts who have evaluated the expansive literature to provide you with one resource covering all aspects of toxicology biomarkers Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure and effect of chemicals of different classes Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation and much more
Biomarkers For Traumatic Brain Injury
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Author : Svetlana Dambinova
language : en
Publisher: Royal Society of Chemistry
Release Date : 2012
Biomarkers For Traumatic Brain Injury written by Svetlana Dambinova and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Due to injuries sustained in sports and in combat, interest in traumatic brain injury (TBI) has never been greater. This book will fulfill a gap in understanding of what is occurring in the brain following injury that can subsequently be detected in biological fluids and imaging.
Novel Designs Of Early Phase Trials For Cancer Therapeutics
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Author : Shivaani Kummar
language : en
Publisher: Academic Press
Release Date : 2018-05-22
Novel Designs Of Early Phase Trials For Cancer Therapeutics written by Shivaani Kummar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-22 with Medical categories.
Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials. This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials. Brings a comprehensive review and recommendations for new clinical trial designs for modern cancer therapeutics Provides the reader with a better understanding on how to design and implement early phase oncology trials Presents a better and updated understanding of the process of developing new treatments for cancer, the exciting scientific advances and how they are informing drug development
Qa Qc Guidance For Sampling And Analysis Of Sediments Water And Tissues For Dredged Material Evaluations
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Author :
language : en
Publisher:
Release Date : 1995
Qa Qc Guidance For Sampling And Analysis Of Sediments Water And Tissues For Dredged Material Evaluations written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Dredging categories.
Managing Image Collections
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Author : Margot Note
language : en
Publisher: Elsevier
Release Date : 2011-02-03
Managing Image Collections written by Margot Note and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-03 with Computers categories.
This book explores issues surrounding all aspects of visual collection management, taken from real-world experience in creating management systems and digitizing core content. Readers will gain the knowledge to manage the digitization process from beginning to end, assess and define the needs of their particular project, and evaluate digitization options. Additionally, they will select strategies which best meet current and future needs, acquire the knowledge to select the best images for digitization, and understand the legal issues surrounding digitization of visual collections. Offers practical information for the busy information professional Concentrates solely on image management Focuses on unique needs of born digital and digitized images