Synthesis Characterization And Applications Of Thiolated Silk Fibroin

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Synthesis Characterization And Applications Of Thiolated Silk Fibroin

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Author : Jeremy Martinez Talusig
language : en
Publisher:
Release Date : 2022

Synthesis Characterization And Applications Of Thiolated Silk Fibroin written by Jeremy Martinez Talusig and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Cysteine categories.

Thiolated polymers, or thiomers, have demonstrated advanced adhesion to biological surfaces such as mucus membranes due to their ability to form disulfide bonds to the cysteine-rich domains in mucin making them an attractive drug delivery system. Silk fibroin, a protein derived from the Bombyx mori silkworm, offers a biocompatible and biodegradable platform absent in other thiomer systems. However, due to the small percentage of native cysteine residues in silk, installation of additional thiols is essential to create an advanced thiomer adhesive. In this research, covalent attachment of non-native thiols to the tyrosine residues of silk fibroin is accomplished with a high degree of functionalization. The extent of thiol modification is characterized by ultraviolet-visible spectroscopy (UV-VIS), proton nuclear magnetic resonance spectroscopy (1H NMR), and 1H15N heteronuclear multiple bond correlation (HMBC). The reactivity of the thiol handles are probed using fluorescence spectroscopy and the in situ gelling ability of the thiolated silk is investigated using infrared spectroscopy (IR) and rheological measurements.

Biopolymeric Nanomaterials

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Author : Shamsher S. Kanwar
language : en
Publisher: Elsevier
Release Date : 2021-09-24

Biopolymeric Nanomaterials written by Shamsher S. Kanwar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-24 with Technology & Engineering categories.

Biopolymeric Nanomaterials: Fundamentals and Applications outlines the fundamental design concepts and emerging applications of biopolymeric nanomaterials. The book also provides information on emerging applications of biopolymeric nanomaterials, including in biomedicine, manufacturing and water purification, as well as assessing their physical, chemical and biological properties. This is an important reference source for materials scientists, engineers and biomedical scientists who are seeking to increase their understanding of how polymeric nanomaterials are being used for a range of biomedical and industrial applications. Biopolymeric nanomaterials refer to biocompatible nanomaterials, consisting of biopolymers, such as protein (silk, collagen, gelatin, ß-casein, zein, and albumin), protein-mimicked polypeptides and polysaccharides (chitosan, alginate, pullulan, starch, and heparin). Biopolymeric nanomaterials may be used as i) delivery systems for bioactive compounds in food application, (ii) for delivery of therapeutic molecules (drugs and genes), or for (iii) tissue engineering. Provides information on the design concepts and synthesis of biopolymeric nanomaterials in biomedical and industrial applications Highlights the major properties and processing methods for biopolymeric nanomaterials Assesses the major challenges of producing biopolymeric nanomaterials on an industrial scale

Marine Biomaterials

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Author : Sougata Jana
language : en
Publisher: Springer Nature
Release Date : 2022-04-23

Marine Biomaterials written by Sougata Jana and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-23 with Medical categories.

This book provides updated information on marine-based biomedical carriers and their therapeutic potential. Marine biomaterials and bio-based carriers show wide application in pharmaceutical and biomedical fields to deliver small and large molecules. Biomaterial-based composites, scaffolds, or matrix systems are sound systems for controlled and prolonged drug release in target sites and control the premature release of drugs or bioactive compounds. This book discusses essential topics such as the therapeutic potential of marine collagen, management of bone disorders, gene delivery, natural marine compounds in immunomodulation, theranostic applications, tissue engineering, and regeneration. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. Marine biomaterial-based systems are popular for tissue engineering and biomedical imaging. This book is ideal for industry experts, students, and researchers in pharmaceutical sciences and pharmacology.

Metal Nanoparticles

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Author : Daniel L. Fedlheim
language : en
Publisher: CRC Press
Release Date : 2001-10-26

Metal Nanoparticles written by Daniel L. Fedlheim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-26 with Science categories.

A state-of-the-art reference, Metal Nanoparticles offers the latest research on the synthesis, characterization, and applications of nanoparticles. Following an introduction of structural, optical, electronic, and electrochemical properties of nanoparticles, the book elaborates on nanoclusters, hyper-Raleigh scattering, nanoarrays, and several applications including single electron devices, chemical sensors, biomolecule sensors, and DNA detection. The text emphasizes how size, shape, and surface chemistry affect particle performance throughout. Topics include synthesis and formation of nanoclusters, nanosphere lithography, modeling of nanoparticle optical properties, and biomolecule sensors.

Luminescent Metal Nanoclusters

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Author : Sabu Thomas
language : en
Publisher: Woodhead Publishing
Release Date : 2022-06-28

Luminescent Metal Nanoclusters written by Sabu Thomas and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-28 with Science categories.

Luminescent Metal Nanoclusters: Synthesis, Characterization, and Applications provides a comprehensive accounting of various protocols used for the synthesis of metal nanoclusters, their characterization techniques, toxicity evaluation and various applications and future prospects. The book provides detailed experimental routes, along with mechanisms on the formation of benign metallic clusters using biomaterials and a comprehensive review regarding the preparation, properties and prospective applications of these nano clusters in various fields, including therapeutic applications. Various methods to protect nanocluster materials to increase their stability are emphasized, including the incorporation of ligands (protein, small molecule, DNA, thiols). This book addresses a gap in the current literature by bringing together the preparation, characterization and applications of all the possible types of reported metal nanoclusters and their hybrids. It is suitable for materials scientists and engineers in academia and those working in research and development in industry. It may also be of interest to those working in the interdisciplinary nanotechnology community, such as physical chemists. Covers the most relevant material categories of luminescent nanoclusters such as metal nanoclusters, nano composites and alloy nanoclusters Provides a comprehensive overview of the various available methods used for the protection of nanoclusters Discusses the latest advances and future opportunities in addressing challenges in producing benign nanomaterials such as toxicity and stability

Green Synthesis Of Silver Nanomaterials

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Author : Kamel A. Abd-Elsalam
language : en
Publisher: Elsevier
Release Date : 2021-10-28

Green Synthesis Of Silver Nanomaterials written by Kamel A. Abd-Elsalam and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-28 with Technology & Engineering categories.

Green Synthesis of Silver Nanomaterials illustrates how to biologically scale up silver nanoparticle synthesis. This book covers green synthesis of silver nanomaterials, via plants, agricultural waste, fungi, and microorganisms. Sections cover the synthesis and characterization of chemical and green synthesis, various types of silver nanomaterialism, the ability of different fungal species, such as filamentous fungi, to produce silver nanoparticles, the microbial synthesis of silver NMs, biosynthesis mechanisms, toxicity, fate and commercialization. As examples, greener pathways and mechanisms, toxicity of silver nanoparticles in aquatic life and in natural eco-systems, and strategies for the scaling up of green-synthesized nanomaterials are discussed. With the extended work in enhancing nanomaterials synthesis performance, and discovering their biomedical, environmental, and agricultural applications, it is hoped that the execution of these methods on a large scale and their industrial applications in different fields will take place in the near future. Assesses the impact of a large variety of silver-based nanostructures in the biomedical, environmental and agri-food sectors Discusses the major synthesis methods used for effectively processing plant-based silver nanoparticles Outlines the potential and major challenges for adopting green synthesis methods on a mass scale

Innovative Bioceramics In Translational Medicine I

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Author : Andy H. Choi
language : en
Publisher: Springer Nature
Release Date : 2022-01-01

Innovative Bioceramics In Translational Medicine I written by Andy H. Choi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-01 with Science categories.

This book is part of a two-part volume book that highlights the latest advances in innovative bioceramics applied in the highly interdisciplinary area referred to as “translational medicine”. This volume covers the basic principles and techniques used in the manufacture of bioceramics and biocomposites for various biomedical applications including drug delivery, implantable bionics and the development of the cardiac pacemaker, and bone tissue engineering. Furthermore, self-healing materials have been attracting increasing interest in both engineering and medical applications during the past two decades. Self-healing hydrogels are particularly interesting because of their ability to repair structural damages and recover their original functions, specifically in tissue engineering.

Bioconjugate Techniques

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Author : Greg T. Hermanson
language : en
Publisher: Academic Press
Release Date : 2013-07-25

Bioconjugate Techniques written by Greg T. Hermanson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-25 with Science categories.

Bioconjugate Techniques, Third Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates Features full color illustrations Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented

Peptide Based Materials

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Author : Timothy Deming
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-01-13

Peptide Based Materials written by Timothy Deming and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-13 with Technology & Engineering categories.

Synthesis of Polypeptides by Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides, by Jianjun Cheng and Timothy J. Deming.- Peptide Synthesis and Self-Assembly, by S. Maude, L. R. Tai, R. P. W. Davies, B. Liu, S. A. Harris, P. J. Kocienski and A. Aggeli.- Elastomeric Polypeptides, by Mark B. van Eldijk, Christopher L. McGann, Kristi L. Kiick andJan C. M. van Hest.- Self-Assembled Polypeptide and Polypeptide Hybrid Vesicles: From Synthesis to Application, by Uh-Joo Choe, Victor Z. Sun, James-Kevin Y. Tan and Daniel T. Kamei.- Peptide-Based and Polypeptide-Based Hydrogels for Drug Delivery and Tissue Engineering, by Aysegul Altunbas and Darrin J. Pochan.-

Polymers For Biomedicine

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Author : Carmen Scholz
language : en
Publisher: John Wiley & Sons
Release Date : 2017-06-28

Polymers For Biomedicine written by Carmen Scholz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-28 with Science categories.

Highlighting dynamic developments in polymer synthesis, this book focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and macromolecules. • Aids researchers developing polymers and materials for biomedical applications • Describes biopolymers from a synthetic perspective, which other similar books do not do • Covers areas that include: cationically-charged macromolecules, pseudo-peptides, polydrugs and prodrugs, controlled radical polymerization, self-assembly, polycondensates, and polymers for surface modification