Peptide Based Materials
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Peptide Based Materials
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Author : Timothy Deming
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-01-10
Peptide Based Materials written by Timothy Deming and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-10 with Technology & Engineering categories.
Synthesis of Polypeptides by Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides, by Jianjun Cheng and Timothy J. Deming.- Peptide Synthesis and Self-Assembly, by S. Maude, L. R. Tai, R. P. W. Davies, B. Liu, S. A. Harris, P. J. Kocienski and A. Aggeli.- Elastomeric Polypeptides, by Mark B. van Eldijk, Christopher L. McGann, Kristi L. Kiick andJan C. M. van Hest.- Self-Assembled Polypeptide and Polypeptide Hybrid Vesicles: From Synthesis to Application, by Uh-Joo Choe, Victor Z. Sun, James-Kevin Y. Tan and Daniel T. Kamei.- Peptide-Based and Polypeptide-Based Hydrogels for Drug Delivery and Tissue Engineering, by Aysegul Altunbas and Darrin J. Pochan.-
Peptide Based Biomaterials
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Author : Mustafa O. Guler
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-11-18
Peptide Based Biomaterials written by Mustafa O. Guler and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-18 with Science categories.
Research and new tools in biomaterials development by using peptides are currently growing, as more functional and versatile building blocks are used to design a host of functional biomaterials via chemical modifications for health care applications. It is a field that is attracting researchers from across soft matter science, molecular engineering and biomaterials science. Covering the fundamental concepts of self-assembly, design and synthesis of peptides, this book will provide a solid introduction to the field for those interested in developing functional biomaterials by using peptide derivatives. The bioactive nature of the peptides and their physical properties are discussed in various applications in biomedicine. This book will help researchers and students working in biomaterials and biomedicine fields and help their understanding of modulating biological processes for disease diagnosis and treatments.
Peptides And Peptide Based Biomaterials And Their Biomedical Applications
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Author : Anwar Sunna
language : en
Publisher: Springer
Release Date : 2017-10-26
Peptides And Peptide Based Biomaterials And Their Biomedical Applications written by Anwar Sunna and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-26 with Science categories.
Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.
Protein Based Materials
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Author : David Kaplan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Protein Based Materials written by David Kaplan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Nature learned long ago how useful proteins are as a diverse set of building blocks to make materials with very diverse properties. Spider webs, egg whites, hair follicles, and skeletal muscles are all largely protein. This book provides a glimpse into both nature's strategies for the design and produc tion of protein-based materials, and how scientists have been able to go beyond the constraints of natural materials to produce synthetic analogs with potentially wider ranges of properties. The work presented is very much the beginning of the story. Only recently has there been much progress in obtaining a molecular understanding of some of nature's com plex materials, and the mimicry or replacement of these by synthetic or genetically engineered variants is a field still in its infancy. Yet this book will serve as a useful introduction for those wishing to get started in what is sure to be an active and productive field throughout the 21st century. The authors represent a wide range of interests and expertise, and the topics chosen are comprehensive. Charles R. Cantor Center for Advanced Biotechnology Boston University Series Preface The properties of materials depend on the nature of the macromolecules, small molecules and inorganic components and the interfaces and interac tions between them. Polymer chemistry and physics, and inorganic phase structure and density are major factors that influence the performance of materials.
Peptide Materials
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Author : Carlos Aleman
language : en
Publisher: John Wiley & Sons
Release Date : 2013-03-29
Peptide Materials written by Carlos Aleman and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-29 with Technology & Engineering categories.
Peptides are the building blocks of the natural world; with varied sequences and structures, they enrich materials producing more complex shapes, scaffolds and chemical properties with tailorable functionality. Essentially based on self-assembly and self-organization and mimicking the strategies that occur in Nature, peptide materials have been developed to accomplish certain functions such as the creation of specific secondary structures (a- or 310-helices, b-turns, b-sheets, coiled coils) or biocompatible surfaces with predetermined properties. They also play a key role in the generation of hybrid materials e.g. as peptide-inorganic biomineralized systems and peptide/polymer conjugates, producing smart materials for imaging, bioelectronics, biosensing and molecular recognition applications. Organized into four sections, the book covers the fundamentals of peptide materials, peptide nanostructures, peptide conjugates and hybrid nanomaterials, and applications with chapters including: Properties of peptide scaffolds in solution and on solid substrates Nanostructures, peptide assembly, and peptide nanostructure design Soft spherical structures obtained from amphiphilic peptides and peptide-polymer hybrids Functionalization of carbon nanotubes with peptides Adsorption of peptides on metal and oxide surfaces Peptide applications including tissue engineering, molecular switches, peptide drugs and drug delivery Peptide Materials: From Nanostructures to Applications gives a truly interdisciplinary review, and should appeal to graduate students and researchers in the fields of materials science, nanotechnology, biomedicine and engineering as well as researchers in biomaterials and bio-inspired smart materials.
Structure Dynamics And Applications Of Peptide Based Nanomaterials
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Author : Pim W. J. M. Frederix
language : en
Publisher:
Release Date : 2013
Structure Dynamics And Applications Of Peptide Based Nanomaterials written by Pim W. J. M. Frederix and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
Peptide-based nanomaterials have rapidly gained interest over the last 10 years, because of their potential uses in biomedicine, nanotechnology and catalysis. Short peptides can readily self-assemble into ordered structures on the nanometer length scale. The design rules for these constructs are not fully understood yet, which is a key issue in engineering new functional nanomaterials. This thesis discusses how infrared spectroscopy and computational chemistry can contribute to the understanding of structure and dynamics of peptide-based selfassembled systems. Quantum mechanical calculations will be discussed in the light of determining stacking interactions between aromatic peptide amphiphiles and predicting their infrared absorptions bands. Furthermore, in case studies of various peptides, both IR spectroscopy and all-atom MD are demonstrated to be sensitive to small changes in the supramolecular structure as a consequence of variations in the amino acid side chains of the peptides under study. However, currently all-atom MD is still somewhat limited by computational costs and the specific assignments of the bands in IR spectra are not always clear. With a lower level of detail in MD simulations, information relevant to the time and length scales of the process of self-assembly can be obtained. The coarse-grain simulation protocol developed here shows good agreement with experiments in terms of predicting a peptide's propensity to aggregate and can reproduce morphological features of self-assembled systems. Finally, these peptide-based materials are applied in encapsulating an enzyme active site mimic that is of relevance for the cheap, environmentally friendly production of hydrogen as a fuel. Using time-resolved infrared spectroscopy it is shown that the hydrogel environment formed by a short, amphiphilic peptide protected the enzyme 15 mimic both from degradation by oxygen and UV irradiation. This type of peptide scaffolding for hydrogenase mimics has potential in creating an artificial enzyme for the reversible oxidation of hydrogen.
Peptide Synthesis And Applications
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Author : John Howl
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Peptide Synthesis And Applications written by John Howl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Science categories.
Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.
Peptide Bionanomaterials
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Author : Mohamed A. Elsawy
language : en
Publisher: Springer Nature
Release Date : 2023-08-28
Peptide Bionanomaterials written by Mohamed A. Elsawy and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-28 with Science categories.
Molecular self-assembly has been exploited by nature for developing the higher functional macromolecular structures of both the genome and proteome. Inspired by nature, there has been a surge of research, in the last two decades, for the molecular engineering of peptide-based self-assembling nanostructures, adopting the bottom-up design approach. This book gives the reader an overview on the design rules for de novo self-assembling peptide and reviews the diverse range of bioinspired peptide nanostructures such as β-sheet and β-hairpin, α-helical and coiled coil, self-assembling short peptides and peptidomimetics, collagen-based and elastin-like peptides, silk peptides, peptide amphiphiles, peptides co-polymers and others. The book also covers the wide variety of responsive and functional biomaterials that have been innovated based on those nanostructures for various applications ranging from tissue engineering, therapeutics and drug delivery to antimicrobial nanomaterials and biosensors. Finally, the book also discusses the peptide bionanomaterials global market and the future of the emerging industry. Chapter “Characterization of Peptide-Based Nanomaterials” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Peptide Based Drug Design
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Author : Laszlo Otvos
language : en
Publisher: Humana Press
Release Date : 2008-10-09
Peptide Based Drug Design written by Laszlo Otvos and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-09 with Medical categories.
Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and the actual production of difficult sequences. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and the Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Peptide-Based Drug Design: Methods and Protocols shows its subject to be an independent science on the rise, and provides scientists with a clear, concise guide for continuing this vital research.
Self Assembled Peptide Nanostructures
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Author : Jaime Castillo
language : en
Publisher: CRC Press
Release Date : 2012-11-21
Self Assembled Peptide Nanostructures written by Jaime Castillo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-21 with Medical categories.
The self-organization of bionanostructures into well-defined functional machineries found in nature has been a priceless source of ideas for researchers. The molecules of life, proteins, DNA, RNA, etc., as well as the structures and forms that these molecules assume serve as rich sources of ideas for scientists or engineers who are interested in developing bio-inspired materials for innovations in biomedical fields. In nature, molecular self-assembly is a process by which complex three-dimensional structures with well-defined functions are constructed, starting from simple building blocks such as proteins and peptides. This book introduces readers to the theory and mechanisms of peptide self-assembly processes. The authors present the more common peptide self-assembled building blocks and discuss how researchers from different fields can apply self-assembling principles to bionanotechnology applications. The advantages and challenges are mentioned together with examples that reflect the state of the art of the use of self-assembled peptide building blocks in nanotechnology.