Self Assembling Biomaterials
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Self Assembling Biomaterials
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Author : Helena S. Azevedo
language : en
Publisher: Woodhead Publishing
Release Date : 2018-04-17
Self Assembling Biomaterials written by Helena S. Azevedo and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-17 with Technology & Engineering categories.
Self-assembling biomaterials: molecular design, characterization and application in biology and medicine provides a comprehensive coverage on an emerging area of biomaterials science, spanning from conceptual designs to advanced characterization tools and applications of self-assembling biomaterials, and compiling the recent developments in the field. Molecular self-assembly, the autonomous organization of molecules, is ubiquitous in living organisms and intrinsic to biological structures and function. Not surprisingly, the exciting field of engineering artificial self-assembling biomaterials often finds inspiration in Biology. More important, materials that self-assemble speak the language of life and can be designed to seamlessly integrate with the biological environment, offering unique engineering opportunities in bionanotechnology. The book is divided in five parts, comprising design of molecular building blocks for self-assembly; exclusive features of self-assembling biomaterials; specific methods and techniques to predict, investigate and characterize self-assembly and formed assemblies; different approaches for controlling self-assembly across multiple length scales and the nano/micro/macroscopic properties of biomaterials; diverse range of applications in biomedicine, including drug delivery, theranostics, cell culture and tissue regeneration. Written by researchers working in self-assembling biomaterials, it addresses a specific need within the Biomaterials scientific community. - Explores both theoretical and practical aspects of self-assembly in biomaterials - Includes a dedicated section on characterization techniques, specific for self-assembling biomaterials - Examines the use of dynamic self-assembling biomaterials
Engineering New Self Assembling Biomaterials Based On Beta Sheet Forming Peptides
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Author : Joel Henderson Collier
language : en
Publisher:
Release Date : 2003
Engineering New Self Assembling Biomaterials Based On Beta Sheet Forming Peptides written by Joel Henderson Collier and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
This thesis deals with the development of novel strategies for self-assembling biomaterials based on short beta-sheet fibril-forming peptides. These materials are potentially useful for a variety of biomedical applications, including tissue engineering and controlled drug release, and several aspects of these materials have been explored in this thesis in an effort to improve their clinical utility. First, a strategy for rapidly and uniformly triggering peptide self-assembly was developed. Stimulus-sensitive liposomes were utilized to sequester salts and release them in response to stimuli such as warming to body temperature or exposure to near infra-red light. Triggered salt release in turn initiated rapid self-assembly of extravesicular peptide and the transformation of the peptide/liposome suspension from a solution to a hydrogel. We show that peptide self-assembly can be rapidly, uniformly, and specifically triggered, with the storage modulus increasing three orders of magnitude upon triggering. This rapid triggering strategy is potentially useful for injectable biomaterial applications. In the second research thrust, a self-assembling peptide was developed that also possessed enzymatic activity for the cross-linking enzyme tissue transglutaminase. We then utilized tissue transglutaminase to conjugate cell-interactive peptides to the self-assembled structure and investigated cell attachment to these functionalized scaffolds. Such a strategy is potentially useful for designing biospecific self-assembling scaffolds for tissue engineering or wound healing. In the final research focus, to modulate the nanostructure of the self-assembled fibrillar structures, we developed a series of self-assembling polyethylene glycol-conjugated peptides. We found that polyethylene glycol conjugation significantly altered fibril morphology, including width, length, and degree of lateral aggregation. As previous beta-sheet fibrillar self-assembled materials have shown particular intransigence to such modification of the fibrillar structure, this strategy may be a useful route for tailoring the physical properties of these materials. As a whole, the strategies developed in this thesis address previous shortcomings of beta-sheet peptide-based self-assembling materials in an effort to bring them closer to clinical application.
Self Assembling Biomaterials
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Author : Helena S. Azevedo
language : en
Publisher: Woodhead Publishing
Release Date : 2018-04-19
Self Assembling Biomaterials written by Helena S. Azevedo and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-19 with Technology & Engineering categories.
Self-assembling biomaterials: molecular design, characterization and application in biology and medicine provides a comprehensive coverage on an emerging area of biomaterials science, spanning from conceptual designs to advanced characterization tools and applications of self-assembling biomaterials, and compiling the recent developments in the field. Molecular self-assembly, the autonomous organization of molecules, is ubiquitous in living organisms and intrinsic to biological structures and function. Not surprisingly, the exciting field of engineering artificial self-assembling biomaterials often finds inspiration in Biology. More important, materials that self-assemble speak the language of life and can be designed to seamlessly integrate with the biological environment, offering unique engineering opportunities in bionanotechnology. The book is divided in five parts, comprising design of molecular building blocks for self-assembly; exclusive features of self-assembling biomaterials; specific methods and techniques to predict, investigate and characterize self-assembly and formed assemblies; different approaches for controlling self-assembly across multiple length scales and the nano/micro/macroscopic properties of biomaterials; diverse range of applications in biomedicine, including drug delivery, theranostics, cell culture and tissue regeneration. Written by researchers working in self-assembling biomaterials, it addresses a specific need within the Biomaterials scientific community.
Biomaterials Fabrication And Processing Handbook
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Author : Paul K. Chu
language : en
Publisher: CRC Press
Release Date : 2008-03-27
Biomaterials Fabrication And Processing Handbook written by Paul K. Chu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-27 with Medical categories.
This volume focuses on a variety of production and processing aspects of the latest biomaterials. It discusses how scaffolds are used in tissue engineering and describes common implant materials, such as hard tissue, blood contacting, and soft tissue. The book also examines the important role nanotechnology plays in the preparation of drugs, protein delivery, tissue engineering, cardiovascular biomaterials, hard tissue replacements, biosensors, and bio-MEMS. With contributions from renowned international experts and extensive reference lists in each chapter, this book provides detailed, practical information to produce biomaterials and employ them in biomedicine.
Self Assembled Peptide Nanostructures
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Author : Jaime Castillo
language : en
Publisher: CRC Press
Release Date : 2012-11-21
Self Assembled Peptide Nanostructures written by Jaime Castillo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-21 with Medical categories.
The self-organization of bionanostructures into well-defined functional machineries found in nature has been a priceless source of ideas for researchers. The molecules of life, proteins, DNA, RNA, etc., as well as the structures and forms that these molecules assume serve as rich sources of ideas for scientists or engineers who are interested in developing bio-inspired materials for innovations in biomedical fields. In nature, molecular self-assembly is a process by which complex three-dimensional structures with well-defined functions are constructed, starting from simple building blocks such as proteins and peptides. This book introduces readers to the theory and mechanisms of peptide self-assembly processes. The authors present the more common peptide self-assembled building blocks and discuss how researchers from different fields can apply self-assembling principles to bionanotechnology applications. The advantages and challenges are mentioned together with examples that reflect the state of the art of the use of self-assembled peptide building blocks in nanotechnology.
Biomaterial Fabrication Techniques
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Author : Adnan Haider
language : en
Publisher: Bentham Science Publishers
Release Date : 2022-11-22
Biomaterial Fabrication Techniques written by Adnan Haider and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-22 with Science categories.
This reference is a guide to biomaterial fabrication techniques. The book comprises ten chapters introducing the reader to a range of biomaterial synthesis while highlighting biomedical applications. Each chapter presents a review of the topic followed by updated information about relevant core and applied concepts in an easy to understand format. The first two chapters present vital information about biomaterial components, such as polymer nanocomposites and scaffolds, and the strategies used for their fabrication. The proceeding chapters explain the principles of the most widely used fabrication techniques, and their application in detail. These include freeze drying, electrospinning, 3D printing, multiphoton lithography, particulate leaching, supramolecular self assembly, solvent casting and melt molding. The book is an essential primer on biomaterial synthesis for students and early career researchers in the field of biomedical engineering, applied chemistry and tissue engineering.
Peptide Based Biomaterials
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Author : Mustafa O. Guler
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-11-18
Peptide Based Biomaterials written by Mustafa O. Guler and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-18 with Science categories.
Research and new tools in biomaterials development by using peptides are currently growing, as more functional and versatile building blocks are used to design a host of functional biomaterials via chemical modifications for health care applications. It is a field that is attracting researchers from across soft matter science, molecular engineering and biomaterials science. Covering the fundamental concepts of self-assembly, design and synthesis of peptides, this book will provide a solid introduction to the field for those interested in developing functional biomaterials by using peptide derivatives. The bioactive nature of the peptides and their physical properties are discussed in various applications in biomedicine. This book will help researchers and students working in biomaterials and biomedicine fields and help their understanding of modulating biological processes for disease diagnosis and treatments.
Nanobiomaterials
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Author : Thandapani Gomathi
language : en
Publisher: CRC Press
Release Date : 2023-10-13
Nanobiomaterials written by Thandapani Gomathi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-13 with Science categories.
Nanobiomaterials: Research Trends and Applications – Biomaterials are derived from natural resources such as plants, animals and marine sources. These biomaterials have advanced applications, across a range of key industries due to their low cost, being easy to process, being biocompatible and so on. The modification of biomaterials in the nanoform enhances their applications. The book begins with an overview of nanobiomaterials, processing, classifications, fabrication and sustainability. In-depth chapters in Part I address the most recent methods and techniques for physicochemical characterisation, processing of blends and composites based on nanomaterials, and separation. Chapters in Part II focus on the biological and biomedical applications specifically in antimicrobial chemotherapy, drug delivery, tissue engineering, cancer therapeutics, robust biosolar cells, and 3D printing. The chapters in Part III mostly focus on environmental applications, including wastewater treatment, water desalination, bioremediation, and agricultural uses. The book is extremely useful for scientists, R&D specialists, designers, and engineers across sectors and disciplines who are interested in using biopolymers for parts and products.
Nanobiomaterials Handbook
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Author : Balaji Sitharaman
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Nanobiomaterials Handbook written by Balaji Sitharaman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Nanobiomaterials exhibit distinctive characteristics, including mechanical, electrical, and optical properties, which make them suitable for a variety of biological applications. Because of their versatility, they are poised to play a central role in nanobiotechnology and make significant contributions to biomedical research and healthcare. Nanobio
Smart Biomaterial Devices
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Author : A.K. Bajpai
language : en
Publisher: CRC Press
Release Date : 2016-12-19
Smart Biomaterial Devices written by A.K. Bajpai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-19 with Medical categories.
Polymers have emerged as one of the most innovative classes of materials in modern materials science, leading to new applications in medicine and pharmacy. This book offers a convincing and understandable approach to polymer biomaterial devices being used in various areas related to biomedical and pharmaceutical fields. The polymer materials finding application as biomaterials are discussed and described in detail pertaining to the areas of artificial implants, orthopedics, ocular devices, dental implants, drug delivery systems, burns and wounds.