Synthesis Of Heterocycles In Contemporary Medicinal Chemistry


Synthesis Of Heterocycles In Contemporary Medicinal Chemistry
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Synthesis Of Heterocycles In Contemporary Medicinal Chemistry


Synthesis Of Heterocycles In Contemporary Medicinal Chemistry
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Author : Zdenko Časar
language : en
Publisher: Springer
Release Date : 2016-07-01

Synthesis Of Heterocycles In Contemporary Medicinal Chemistry written by Zdenko Časar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-01 with Science categories.


The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.



Heterocyclic Chemistry In Drug Discovery


Heterocyclic Chemistry In Drug Discovery
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Author : Jie Jack Li
language : en
Publisher: John Wiley & Sons
Release Date : 2013-04-26

Heterocyclic Chemistry In Drug Discovery written by Jie Jack Li and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-26 with Science categories.


Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in the field review more than 100 years of findings, explaining their relevance to contemporary drug discovery practice. Moreover, these authors have provided plenty of practical guidance and tips based on their own academic and industrial laboratory experience, helping readers avoid common pitfalls. Heterocyclic Chemistry in Drug Discovery is ideal for readers who want to fully realize the almost limitless potential to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features: Several case studies illustrating the role and application of 3, 4, 5, and 6+ heterocyclic ring systems in drug discovery Step-by-step descriptions of synthetic methods and practical techniques Examination of the physical properties for each heterocycle, including NMR data and quantum calculations Detailed explanations of the complexity and intricacies of reactivity and stability for each class of heterocycles Heterocyclic Chemistry in Drug Discovery is recommended as a textbook for organic and medicinal chemistry courses, particularly those emphasizing heterocyclic chemistry. The text also serves as a guide for medicinal and process chemists in the pharmaceutical industry, offering them new insights and new paths to explore for effective drug discovery.



Name Reactions In Heterocyclic Chemistry


Name Reactions In Heterocyclic Chemistry
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Author : Jie Jack Li
language : en
Publisher: John Wiley & Sons
Release Date : 2004-10-11

Name Reactions In Heterocyclic Chemistry written by Jie Jack Li and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-11 with Science categories.


Covers important name reactions relevant to heterocyclic chemistry The field of heterocyclic chemistry has long presented a special challenge for chemists. Because of the enormous amount and variety of information, it is often a difficult topic to cover for undergraduate and graduate chemistry students, even in simplified form. Yet the chemistry of heterocyclic compounds and methods for their synthesis form the bedrock of modern medicinal chemical and pharmaceutical research. Thus there is a great need for high quality, up-to-date, and authoritative books on heterocyclic synthesis helpful to both the professional research chemist as well as the advanced student. Name Reactions in Heterocyclic Chemistry provides a one-stop repository for this important field of organic chemistry. The primary topics include three- and four-membered heterocycles, five-membered heterocycles including indoles, furans, thiophenes, and oxazoles, six-membered heterocycles including quinolines, isoquinolines, and pyrimidines, and other heterocycles. Each name reaction is summarized in seven sections: Description Historical perspective Mechanism Variations and improvements Synthetic utility Experimental References Authored by a team of world-renowned contributors - some of whom have discovered the very reactions they describe - Name Reactions in Heterocyclic Chemistry represents a state-of-the-art resource for students and researchers alike.



Heterocyclic Chemistry


Heterocyclic Chemistry
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Author : Radha R. Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Heterocyclic Chemistry written by Radha R. Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.


This advanced text-cum-reference book presents a comprehensive account of the syntheses, reactions, properties and applications of all the most significant classes of heterocyclic compounds. This second volume in the series is an essential tool not only for advanced undergraduates and graduates, but also for academic and industrial researchers in organic, medicinal, pharmaceutical, dye and agricultural chemistry.



Flow Chemistry For The Synthesis Of Heterocycles


Flow Chemistry For The Synthesis Of Heterocycles
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Author : Upendra K. Sharma
language : en
Publisher: Springer
Release Date : 2018-06-20

Flow Chemistry For The Synthesis Of Heterocycles written by Upendra K. Sharma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-20 with Science categories.


This volume provides an overview of recent developments and scope in the use of flow chemistry in relevance to heterocyclic synthesis. The heterocyclic ring is the most prominent structural motif in the vast majority of natural products as well as pharmaceutical compounds since this facilitates tuneable interactions with the biological target besides conferring a degree of structural and metabolic stability. In recent times, flow chemistry has heralded a paradigm shift in organic synthesis as it offers several unique advantages over conventional methods like drastic acceleration of sluggish transformations, enhanced yields, cleaner reactions etc and is gradually gaining a lot of attention among organic chemist worldwide. Given the importance of heterocycles in natural products, medicinal chemistry and pharmaceuticals, this is a well warranted volume and complements the previous volume of Topics in Organometallic Chemistry ‘Organometallic Flow Chemistry’. This volume offers a versatile overview of the topic, besides discussing the recent progress in the flourishing area of flow chemistry in relevance to heterocyclic chemistry; it will also help researchers to better understand the chemistry behind these reactions. This in turn provides a platform for future innovations towards the designing of novel transformations under continuous flow. Thus, this volume will appeal to both the novices in this field as well as to experts in academia and industry.



Handbook Of Heterocyclic Chemistry


Handbook Of Heterocyclic Chemistry
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Author : Alan R. Katritzky
language : en
Publisher: Elsevier
Release Date : 2010-08-24

Handbook Of Heterocyclic Chemistry written by Alan R. Katritzky and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-24 with Science categories.


Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, the Handbook of Heterocyclic Chemistry is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. Contains more than 1500 clearly drawn structures and reactions. The highly systematic coverage given to the subject makes this one of the most authoritative single-volume accounts of modern heterocyclic chemistry available and should be useful reference for those teaching a heterocyclic course. Covers the structure, reactivity and synthesis of all heterocyclic compounds as distilled from the larger 15-volume reference work Saves researchers time when they require important information on heterocycles--speeding them to thousands of clearly drawn chemical structures and pertinent reviews by leading experts Features 35% new material to compliment the completely revised text



Heterocycles As Chiral Auxiliaries In Asymmetric Synthesis


Heterocycles As Chiral Auxiliaries In Asymmetric Synthesis
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Author : Manfred Braun
language : en
Publisher: Springer Nature
Release Date : 2020-12-08

Heterocycles As Chiral Auxiliaries In Asymmetric Synthesis written by Manfred Braun and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-08 with Science categories.


The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.



Modern Heterocyclic Chemistry 4 Volumes


Modern Heterocyclic Chemistry 4 Volumes
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Author : Julio Alvarez-Builla
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-15

Modern Heterocyclic Chemistry 4 Volumes written by Julio Alvarez-Builla and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-15 with Science categories.


Eine Fülle von Information zum attraktiven Preis bietet Ihnen dieses vierbändige Handbuch der Heterocyclenchemie.



Heterocyclic Chemistry


Heterocyclic Chemistry
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Author : Radha R. Gupta
language : en
Publisher: Springer
Release Date : 2011-12-22

Heterocyclic Chemistry written by Radha R. Gupta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-22 with Science categories.


Today, our world increasingly is conceived of as being molecular. An ever widening range of phenomena are described logically in terms of molecular properties and molecular interactions. The majority of known molecules are heterocyclic and heterocycles dominate the fields of biochemistry, medicinal chemistry, dyestuffs, photographic science and are of increasing importance in many others, including polymers, adhesives, and molecular engineering. Thus, the importance of heterocyclic chemistry continues to increase and this three volume work by Drs. R. R. Gupta, Mahendra Kumar and Vandana Gupta is a welcome addition to the available guides on the subject. Its scope places it in a useful niche between the single-volume texts and monographs of heterocyclic chemistry and the multivolume treatises. The authors have retained the well tried classical approach but have succeeded in placing their own individual spin on their arrangement. They have put together a well selected range from among the most important of the vast array offacts available. This factual material is ordered in a clear and logical fashion over the three volumes. The present work should be of great value to students-and practitioners of heterocyclic chemistry at all levels from the advanced undergraduate upwards. It will be of particular assistance in presenting a clear and modem view of the subject to those who use heterocycles in a variety of other fields and we wish it well.



Heterocyclic Chemistry


Heterocyclic Chemistry
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Author : Thomas Lonsdale Gilchrist
language : en
Publisher: Longman Publishing Group
Release Date : 1992

Heterocyclic Chemistry written by Thomas Lonsdale Gilchrist and has been published by Longman Publishing Group this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Science categories.


Heterocyclic compounds are important natural products and have widespread uses as pharmaceuticals, dyestuffs, agrochemicals, and pigments. This textbook provides a survey of the various types of heterocyclic ring system. The text has been organized in such a way that the general aspects of the chemistry and properties of heterocyclic compounds are described in the first half of the book and specific classes of heterocycles are then discussed in the second half. Both aromatic and nonaromatic ring systems are included. various methods available for synthesising heterocyclic compounds. This chapter has been expanded and brought up to date in the Second Edition. The second half of the book has been re-organized so that the most common aromatic heterocyclic ring systems are introduced first. Modern applications of heterocyclic chemistry in medicine and in organic synthesis are given prominence in this part of the text. The final chapter provides a guide to the current methods of naming heterocyclic compounds. text, and by a set of problems. Throughout the text numerous references are given to socialist reviews and, where appropriate, to papers from the primary literature. chemistry and for students of biochemistry, pharmacology and related subjects who have a good background knowledge of organic chemistry. It should also be useful as a reference source to more advanced workers in these subjects.