Synthetic Mulitvalent Ligands With Diverse Architectures In The Exploration Of Receptor Function
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Synthetic Mulitvalent Ligands With Diverse Architectures In The Exploration Of Receptor Function
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Author : Jason E. Gestwicki
language : en
Publisher:
Release Date : 2002
Synthetic Mulitvalent Ligands With Diverse Architectures In The Exploration Of Receptor Function written by Jason E. Gestwicki and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
Development Of Specifically Functionalized Antagonists For The Exploration Of Multivalent Receptor Ligand Interactions
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Author : Robert M. Owen
language : en
Publisher:
Release Date : 2003
Development Of Specifically Functionalized Antagonists For The Exploration Of Multivalent Receptor Ligand Interactions written by Robert M. Owen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Polymer Scaffolds For Protein Oligomerization
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Author : Byron R. Griffith
language : en
Publisher:
Release Date : 2003
Polymer Scaffolds For Protein Oligomerization written by Byron R. Griffith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Dissertation Abstracts International
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Author :
language : en
Publisher:
Release Date : 2004
Dissertation Abstracts International written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Dissertations, Academic categories.
American Doctoral Dissertations
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Author :
language : en
Publisher:
Release Date : 2002
American Doctoral Dissertations written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Dissertation abstracts categories.
Multivalency
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Author : Jurriaan Huskens
language : en
Publisher: John Wiley & Sons
Release Date : 2018-02-05
Multivalency written by Jurriaan Huskens and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-05 with Science categories.
Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology.
Fragment Based Approaches In Drug Discovery
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Author : Wolfgang Jahnke
language : en
Publisher: John Wiley & Sons
Release Date : 2006-12-13
Fragment Based Approaches In Drug Discovery written by Wolfgang Jahnke and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Science categories.
This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to keep up-to-date on the latest technologies and strategies in pharmaceutical ligand design. The book is clearly divided into three sections on ligand design, spectroscopic techniques, and screening and drug discovery, backed by numerous case studies.
Diversity Oriented Synthesis
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Author : Andrea Trabocchi
language : en
Publisher: John Wiley & Sons
Release Date : 2013-06-17
Diversity Oriented Synthesis written by Andrea Trabocchi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-17 with Science categories.
Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.
Glycopolymers
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Author : Ravin Narain
language : en
Publisher: Smithers Rapra
Release Date : 2014-11-24
Glycopolymers written by Ravin Narain and has been published by Smithers Rapra this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-24 with Medical categories.
Glycopolymers have received considerable interest in recent years due to their increasing potential applications in material science and biomedicine. With better understanding of the role of carbohydrates in biological systems and with recent advances in organic and carbohydrate chemistry, the design and synthesis of glycopolymers have become simpler where significant research efforts have been carried out towards the fabrication of advanced glyco-polymeric architectures for improved performance. This book provides an update on the recent advances on the synthesis of glycopolymers, their characterisations, their biological properties and their applications. The first objective of this book is to provide the readers a detailed overview about the synthesis of glycopolymers via several modern polymerisation techniques. The characterisation of these materials and their solution properties are also discussed. In addition to this, the conjugation of glycopolymers to different types of biomacromolecules are discussed. The second objective of this book is to provide a detailed overview of the applications of glycopolymers. In addition, the biological properties of the glycopolymers as a function of the types of carbohydrates attached, the polymer architectures and compositions are elaborated. This book will provide a quick reference to students and researchers working in both academia and industry.
Foldamers
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Author : Stefan Hecht
language : en
Publisher: John Wiley & Sons
Release Date : 2007-09-24
Foldamers written by Stefan Hecht and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-24 with Science categories.
This truly comprehensive treatise of foldamers, from synthesis to applications in bio-, material-, and nanoscience is at once an introduction to the topic, while providing in-depth accounts on various aspects clearly aimed at the specialist. The book is clearly structured, with the first part concentrating on structure and foldamer design concepts, while the second part covers functional aspects from properties to applications. The international team of expert authors provides overviews of synthetic approaches as well as analytical techniques.