Systemic Autoinflammatory Diseases Clinical Rheumatic Challenges
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Systemic Autoinflammatory Diseases Clinical Rheumatic Challenges
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Author : Eugen Feist
language : en
Publisher:
Release Date : 2021
Systemic Autoinflammatory Diseases Clinical Rheumatic Challenges written by Eugen Feist and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Autoinflammation, as a relatively new field in clinical rheumatology, has gained an increasing importance in recent years. The number of identified entities and affected patients has gradually increased, and some of the involved pathways have already been identified. This progress allows a deeper understanding of closely linked diseases, namely, inflammasomopathies, interferonopathies, Relo-pathies, and proteasome associated syndromes. These insights have not only improved their classification but also helped to identify new treatment targets of pro-inflammatory cytokines, including IL-1ß, IL-6, interferon-, and TNF-alpha. Nevertheless, there is still a high medical need, especially in reliable outcome measures, for confirmation of data from controlled clinical trials and, finally, also for long-term experience from registers. This issue welcomes all types of papers on the broad spectrum of clinical characteristics, prognosis, pathophysiology, and treatment of autoinflammatory diseases. The goal of this Special Issue is to further raise awareness of autoinflammatory processes and to better separate them from well-established autoimmune diseases. It is clear that we have entered a new age in this complex field, linking rheumatology even closer to immunology.
Systemic Autoinflammatory Diseases Clinical Rheumatic Challenges
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Author :
language : en
Publisher:
Release Date : 2021-12-13
Systemic Autoinflammatory Diseases Clinical Rheumatic Challenges written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-13 with Medical categories.
Infections In Systemic Autoimmune Diseases Risk Factors And Management
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Author :
language : en
Publisher: Elsevier
Release Date : 2020-03-24
Infections In Systemic Autoimmune Diseases Risk Factors And Management written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-24 with Medical categories.
Infections in Systemic Autoimmune Diseases: Risk Factors and Management, Volume Sixteen describes the state-of-the-art of the risk factors and management treating the most common systemic autoimmune diseases (SADS). This updated volume consists of an introductory chapter that provides a brief overview of what different types of infectious diseases exist, followed by eight chapters detailing risk factors, guidelines and recommendations per different disease and bacterial infections. International in scope, the list of more than 20 contributors from Europa and America reads like a who's who of clinical researchers in the field. Written by leading international clinical/surgical and scientific experts on Infection problems in systemic autoimmune diseases Provides a practical guide to the safer treatment of infections in patients with autoimmune diseases Includes a number of problems and recommendation that cannot be found in other books Designed as a 'guide to clinical practice' for management and risk interventions required by patients with SAD's
Sjogren S Syndrome
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Author : Alessia Alunno
language : en
Publisher: Academic Press
Release Date : 2016-06-07
Sjogren S Syndrome written by Alessia Alunno and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-07 with Medical categories.
Sjogren's Syndrome: Novel Insights in Pathogenic, Clinical and Therapeutic Aspects provides the reader with an overview of current knowledge about Sjogren's Syndrome. The book summarizes the huge amount of literature concerning related advances in genetic background, pathogenesis, clinical picture, and therapeutic approaches. It integrates basic immunology concepts, clinical aspects, and pharmacological issues. Scientific progress has allowed us to unmask novel pathogenic mechanisms, to perform genome wide studies, and to identify clinical and serological features associated with different disease subsets and, eventually, different disease prognoses. In addition, the increasing knowledge about SS pathogenesis provides the rationale to employ targeted therapies in SS as has already occurred in rheumatoid arthritis and systemic lupus erythematosus. Discusses heterogeneity of topics and audience, from basic immunology to clinical aspects and therapeutics Provides novel lines of investigation and supports the management of patients requiring novel therapeutic approaches Presents a deeper knowledge on SS clinical management as well as on immunological aspects possibly leading to new lines of investigation Offers a bridge between the clinician and the scientist, and vice versa Provides the reader with most recent and relevant updates due to the novelty of topics
Challenges In Rheumatology
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Author : Miroslav Harjacek
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-12-22
Challenges In Rheumatology written by Miroslav Harjacek and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-22 with Medical categories.
Rheumatology is a subspecialty of medicine that focuses on the biology, cause, diagnosis and the treatment of a variety of musculoskeletal and other systemic diseases. The field of rheumatology is expanding rapidly and several very exciting developments have occurred during the recent years. Firstly, there has been a new dramatic understanding of the nature of inflammation and the possibility of specifically regulating the aberrant immune inflammatory response. Secondly, an understanding of pathogenesis has lead to the development of new, more targeted therapies. Challenges in Rheumatology has assembled an impressive group of international experts who have studied specific aspects of certain rheumatic diseases and have extensive experience either in pathophysiology, or with the in-depth diagnosis and/or management of rheumatic patients. They communicate their knowledge and experience to the reader in chapters that are conveniently organized as pathophysiology, clinical manifestations and diagnosis of selected rheumatic diseases, medical and perioperative orthopedic management, and the economic impact of rheumatic diseases. We hope that this book will help trainees become better physicians and scientists, and that it will help practicing rheumatologists to provide better care, and ultimately, improve the quality of life of our patients.
Textbook Of Autoinflammation
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Author : Philip J. Hashkes
language : en
Publisher: Springer
Release Date : 2019-02-13
Textbook Of Autoinflammation written by Philip J. Hashkes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-13 with Medical categories.
This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development. The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.
Pediatric Rheumatology
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Author : Sujata Sawhney
language : en
Publisher: Springer
Release Date : 2016-11-26
Pediatric Rheumatology written by Sujata Sawhney and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-26 with Medical categories.
This book on rheumatology in children is intended to be a handy tool for all professionals interested in this field. It is divided into five sections: General considerations, arthritic problems, connective tissue diseases, systemic vasculitides and finally a section that covers miscellaneous issues such as Immunodeficiencies, bone heath and uveitis. The book has an easy format with each chapter having one or more clinicalvignettes at the start of the chapter. In addition each chapter outlines the learning objectives and key take home messages. At the end of each section a collection of cases to highlight important issues in the clinic are included. The colorful charts, pictures and tables make reading this book an easy task. The authors are leading experts in their fields working at best practices centers globally to provide the reader with state-of-the-art information.
Pulmonary Manifestations Of Rheumatic Disease
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Author : Paul F. Dellaripa
language : en
Publisher: Springer
Release Date : 2014-05-23
Pulmonary Manifestations Of Rheumatic Disease written by Paul F. Dellaripa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-23 with Medical categories.
The spectrum of systemic rheumatologic disease (often termed connective tissue disease) is characterized by autoimmune-mediated organ dysfunction, and the lungs are a frequent target. There are numerous pulmonary manifestations associated with connective tissue diseases, and all patients with rheumatologic disease are at risk of developing associated lung disease. Pulmonary Manifestations of Rheumatic Disease covers the comprehensive management of rheumatologic lung disease, which requires a multi-disciplinary approach and is optimized by active engagement by rheumatologists working closely with pulmonologists and other specialists. The book offers a practical reference using a case-based approach for practicing clinicians in the ongoing assessment and understanding of rheumatologic lung disease, and presents the science and pathophysiology underlying rheumatologic lung diseases. The first text of its kind specifically dedicated to describe diverse, commonplace, and challenging aspects of rheumatologic lung diseases, Pulmonary Manifestations of Rheumatic Disease serves as an invaluable tool for the practicing clinician.
Best Practices And Challenges To The Practice Of Rheumatology An Issue Of Rheumatic Disease Clinics Of North America
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Author : Daniel J. Wallace
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-11-21
Best Practices And Challenges To The Practice Of Rheumatology An Issue Of Rheumatic Disease Clinics Of North America written by Daniel J. Wallace and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-21 with Medical categories.
Guest edited by Drs. Daniel J. Wallace and R. Swamy Venuturupalli, this issue of Rheumatic Disease Clinics will cover several key areas of interest related to Best Practices and Challenges to the Practice of Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman of Cedars-Sinai. Articles in this issue include, but are not limited to: The Economics of Rheumatology Practice in the United States, Manpower trends in rheumatology, Challenges to practicing rheumatology in an academic center, Challenges in practicing rheumatology in a government setting, Challenges to practicing rheumatology in a small private practice setting, Challenges to working in a large multispecialty organization, Challenges to practicing pediatric rheumatology, Clinical trials in rheumatology, Challenges in having an infusion center, Implementing treatment to target in the clinic, Future directions: implementing new technologies in clinical practice, Possible Challenges in Optimizing Medical Education for Rheumatologists, and the challenges of approaching and managing gout.
Rheumatic Diseases And Syndromes Induced By Cancer Immunotherapy
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Author : Maria E. Suarez-Almazor
language : en
Publisher: Springer Nature
Release Date : 2021-02-16
Rheumatic Diseases And Syndromes Induced By Cancer Immunotherapy written by Maria E. Suarez-Almazor and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-16 with Medical categories.
With the increasing use of immune checkpoint inhibitors (ICI) across various cancers, the trends for indication at earlier stages, and the use of combination immunotherapy, the frequency of ICI-induced immune-related adverse events (irAE) is expected to grow substantially. Management of these irAE is challenging as it requires not only consideration of the toxicity but also risk-benefit ratios with respect to the primary cancer. Several rheumatic irAE have been reported with ICI therapy including arthritis, myositis, polymyalgia-like syndromes, sicca/Sjogren-like manifestations, and several other less common systemic autoimmune features commonly associated with connective tissue disease. This handbook provides clinicians with a comprehensive overview of the management of rheumatic irAE that develop from cancer immunotherapy. It focuses on the irAE seen with ICI, the most frequently used agents in treating cancer. It provides an overview of cancer immunology, immunotoxicity, and immunotherapies such as ICI, cytokine-based therapy, and CART. It examines the epidemiology, clinical manifestations, diagnosis, differential diagnosis, and treatment of a variety of rheumatic immune-related adverse events arising from these therapies. Chapters also cover cancer immunotherapy in patients with preexisting rheumatic diseases such as inflammatory arthritis and other connective tissue disorders. The book helps clinicians to distinguish the current types of cancer immunotherapy and general toxicity patterns, recognize and diagnose rheumatic clinical syndromes, understand the pathogenesis of irAE, and consider risk–benefit ratios when managing patients with rheumatic irAE. Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy is an essential resource for physicians and related professionals, residents, fellows, graduate students and nurses alike in rheumatology, clinical immunology, oncology, and internal medicine.