Systems And Synthetic Metabolic Engineering
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Systems Metabolic Engineering
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Author : Christoph Wittmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-15
Systems Metabolic Engineering written by Christoph Wittmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-15 with Science categories.
Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.
Systems And Synthetic Metabolic Engineering
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Author : Yanfeng Liu
language : en
Publisher: Academic Press
Release Date : 2020-07-10
Systems And Synthetic Metabolic Engineering written by Yanfeng Liu and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-10 with Science categories.
Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area. - Discusses the current progress of metabolic engineering, focusing on systems biology and synthetic biology - Covers introductory, regulatory, strategies, production and challenges in the field - Written technically for synthetic biologists, researchers, students, industrialists, policymakers and stakeholders
Systems Biology And Synthetic Biology
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Author : Pengcheng Fu
language : en
Publisher: John Wiley & Sons
Release Date : 2009-08-13
Systems Biology And Synthetic Biology written by Pengcheng Fu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-13 with Technology & Engineering categories.
The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology technologies to study biological systems, while synthetic biology depends on knowledge obtained from systems biology approaches.
Metabolic Pathway Engineering
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Author : Jean F. Challacombe
language : en
Publisher: CRC Press
Release Date : 2021-07-14
Metabolic Pathway Engineering written by Jean F. Challacombe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-14 with Medical categories.
Metabolic systems engineering combines the tools and approaches of systems biology, synthetic biology, and evolutionary engineering. This book reviews studies on metabolism, from the earliest work of Lavoisier and Buchner to current cutting-edge research in metabolic systems engineering. This technology has been used in bioengineering applications to create high-performing microbes and plants that produce important chemicals, pharmaceuticals, crops, and other natural products. Current applications include optimizing metabolic pathways to enhance degradation of biomass for biofuel production and accelerated processing of environmental waste products and contaminants. The book includes examples to illustrate the applications of this technology in the optimization of metabolic pathways to create robust industrial strains as well as in the engineering of biological processes involving health and diseases of humans, animals, and plants. Written by a seasoned computational biologist with many years of experience in genomics, bioinformatics, and systems biology, this book will appeal to anyone interested in metabolic systems analysis and metabolic pathway engineering.
Metabolic Engineering
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Author : Sang Yup Lee
language : en
Publisher: CRC Press
Release Date : 1999-09-29
Metabolic Engineering written by Sang Yup Lee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-29 with Science categories.
This unique reference/text presents the basic theory and practical applications of metabolic engineering (ME). It offers systematic analysis of complex metabolic pathways and ways of employing recombinant DNA techniques to alter cell behavior, metabolic patterns, and product formation. Treating ME as a distinct subfield of genetic engineering, the book demonstrates new means of enabling cells to produce valuable proteins, polypeptides, and primary and secondary metabolites. Written by more than 35 leading international experts in the field, this book discusses metabolic engineering in plant and mammalian cells, bacteria, and yeasts and assesses metabolic engineering applications in agriculture, pharmaceuticals, and environmental systems. It illuminates the potential of the "cell factory" model for production of chemicals and therapeutics and examines methods for developing new antiviral and antibacterial molecules and effective gene and somatic-cell therapies. Metabolic Engineering also addresses the use of metabolic flux analysis, metabolic control analysis, and online metabolic flux analysis.
The Science And Applications Of Synthetic And Systems Biology
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2011-12-30
The Science And Applications Of Synthetic And Systems Biology written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-30 with Science categories.
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
An Introduction To Metabolic And Cellular Engineering
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Author : Sonia Cortassa
language : en
Publisher: World Scientific
Release Date : 2002
An Introduction To Metabolic And Cellular Engineering written by Sonia Cortassa and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Science categories.
Metabolic and cellular engineering is a powerful alliance of two technologies: genetics-molecular biology and fermentation technology.
Industrial Biotechnology
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Author : Christoph Wittmann
language : en
Publisher: John Wiley & Sons
Release Date : 2017-04-10
Industrial Biotechnology written by Christoph Wittmann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-10 with Science categories.
The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses.
Systems Biology
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Author : Bor-Sen Chen
language : en
Publisher: Nova Science Publishers
Release Date : 2014
Systems Biology written by Bor-Sen Chen and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Systems biology categories.
This text not only describes the current developments in systems biology, systems synthetic biology, and systems metabolic engineering for engineering and biology researchers but also discusses challenges and future prospects for systems biology and the concept of systems biology as an integrated platform for bioinformatics, systems synthetic biology, and systems metabolic engineering.
Recent Advances In Biocatalysis And Metabolic Engineering For Biomanufacturing
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Author : Eun Yeol Lee
language : en
Publisher: MDPI
Release Date : 2019-09-23
Recent Advances In Biocatalysis And Metabolic Engineering For Biomanufacturing written by Eun Yeol Lee and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-23 with Science categories.
The use of biocatalysts, including enzymes and metabolically engineered cells, has attracted a great deal of attention in the chemical and bio-industry, because biocatalytic reactions can be conducted under environmentally-benign conditions and in more sustainable ways. The catalytic efficiency and chemo-, regio-, and stereo-selectivity of enzymes can be enhanced and modulated using protein engineering. Metabolic engineering seeks to enhance cellular biosynthetic productivity of target metabolites via controlling and redesigning metabolic pathways using multi-omics analysis, genome-scale modeling, metabolic flux control, and reconstruction of novel pathways. The aim of this book is to cover the recent advances in biocatalysis and metabolic engineering for biomanufacturing of biofuels, chemicals, biomaterials, and pharmaceuticals. Reviews and original research articles on the development of new strategies to improve the catalytic efficiency of enzymes, biosynthetic capability of cell factories, and their applications in production of various bioproducts and chemicals are included.