Systems Biology And Bioinformatics


Systems Biology And Bioinformatics
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Systems Biology And Bioinformatics


Systems Biology And Bioinformatics
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Author : Kayvan Najarian
language : en
Publisher: CRC Press
Release Date : 2009-04-13

Systems Biology And Bioinformatics written by Kayvan Najarian and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-13 with Medical categories.


The availability of molecular imaging and measurement systems enables today's biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods



Bioinformatics And Systems Biology


Bioinformatics And Systems Biology
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Author : Frederick Marcus
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-07-22

Bioinformatics And Systems Biology written by Frederick Marcus and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-22 with Science categories.


Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.



Bioinformatics For Systems Biology


Bioinformatics For Systems Biology
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Author : Stephen Krawetz
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-11

Bioinformatics For Systems Biology written by Stephen Krawetz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-11 with Science categories.


Bioinformatics for Systems Biology bridges and unifies many disciplines. It presents the life scientist, computational biologist, and mathematician with a common framework. Only by linking the groups together may the true life sciences revolution move forward.



Emerging Trends In Applications And Infrastructures For Computational Biology Bioinformatics And Systems Biology


Emerging Trends In Applications And Infrastructures For Computational Biology Bioinformatics And Systems Biology
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Author : Hamid R Arabnia
language : en
Publisher: Morgan Kaufmann
Release Date : 2016-03-25

Emerging Trends In Applications And Infrastructures For Computational Biology Bioinformatics And Systems Biology written by Hamid R Arabnia and has been published by Morgan Kaufmann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-25 with Computers categories.


Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology: Systems and Applications covers the latest trends in the field with special emphasis on their applications. The first part covers the major areas of computational biology, development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques for the study of biological and behavioral systems. The second part covers bioinformatics, an interdisciplinary field concerned with methods for storing, retrieving, organizing, and analyzing biological data. The book also explores the software tools used to generate useful biological knowledge. The third part, on systems biology, explores how to obtain, integrate, and analyze complex datasets from multiple experimental sources using interdisciplinary tools and techniques, with the final section focusing on big data and the collection of datasets so large and complex that it becomes difficult to process using conventional database management systems or traditional data processing applications. Explores all the latest advances in this fast-developing field from an applied perspective Provides the only coherent and comprehensive treatment of the subject available Covers the algorithm development, software design, and database applications that have been developed to foster research



Emerging Trends In Computational Biology Bioinformatics And Systems Biology


Emerging Trends In Computational Biology Bioinformatics And Systems Biology
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Author : Hamid R Arabnia
language : en
Publisher: Morgan Kaufmann
Release Date : 2015-08-11

Emerging Trends In Computational Biology Bioinformatics And Systems Biology written by Hamid R Arabnia and has been published by Morgan Kaufmann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-11 with Computers categories.


Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques. • Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid computing for the storage and access of big data sets. • Presents a systematic approach for storing, retrieving, organizing, and analyzing biological data using software tools with applications to general principles of DNA/RNA structure, bioinformatics and applications, genomes, protein structure, and modeling and classification, as well as microarray analysis. • Provides a systems biology perspective, including general guidelines and techniques for obtaining, integrating, and analyzing complex data sets from multiple experimental sources using computational tools and software. Topics covered include phenomics, genomics, epigenomics/epigenetics, metabolomics, cell cycle and checkpoint control, and systems biology and vaccination research. • Explains how to effectively harness the power of Big Data tools when data sets are so large and complex that it is difficult to process them using conventional database management systems or traditional data processing applications. Discusses the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological and behavioral systems. Presents a systematic approach for storing, retrieving, organizing and analyzing biological data using software tools with applications. Provides a systems biology perspective including general guidelines and techniques for obtaining, integrating and analyzing complex data sets from multiple experimental sources using computational tools and software.



Systems Biology And Bioinformatics


Systems Biology And Bioinformatics
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Author : Kayvan Najarian
language : en
Publisher: CRC Press
Release Date : 2017-05-31

Systems Biology And Bioinformatics written by Kayvan Najarian and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-31 with categories.


The availability of molecular imaging and measurement systems enables today's biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods used in what is being coined the digital eraof biology. Written by field experts with proven track records, this authoritative textbook first provides an introduction to systems biology and its impact on biology and medicine. The book then reviews the basic principles of molecular and cell biology using a system-oriented approach, with a brief description of the high-throughput biological experiments that produce databases. The text includes techniques to discover genes, perform nucleotide and amino acid sequence matching, and estimate static gene dynamic pathways. The book also explains how to use system-oriented models to predict the behavior of biological systems for important applications such as rational drug design. The numerous examples and problem sets allow students to confidently explore practical systems biology applications using real examples with real biological data, making Systems Biology and Bioinformatics: A Computational Approachan ideal text for senior undergraduate and first-year graduate students.



Systems Biology


Systems Biology
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Author : Jens Nielsen
language : en
Publisher: John Wiley & Sons
Release Date : 2017-05-30

Systems Biology written by Jens Nielsen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-30 with Computers categories.


Comprehensive coverage of the many different aspects of systems biology, resulting in an excellent overview of the experimental and computational approaches currently in use to study biological systems. Each chapter represents a valuable introduction to one specific branch of systems biology, while also including the current state of the art and pointers to future directions. Following different methods for the integrative analysis of omics data, the book goes on to describe techniques that allow for the direct quantification of carbon fluxes in large metabolic networks, including the use of 13C labelled substrates and genome-scale metabolic models. The latter is explained on the basis of the model organism Escherichia coli as well as the human metabolism. Subsequently, the authors deal with the application of such techniques to human health and cell factory engineering, with a focus on recent progress in building genome-scale models and regulatory networks. They highlight the importance of such information for specific biological processes, including the ageing of cells, the immune system and organogenesis. The book concludes with a summary of recent advances in genome editing, which have allowed for precise genetic modifications, even with the dynamic control of gene expression. This is part of the Advances Biotechnology series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question.



Systemic Approaches In Bioinformatics And Computational Systems Biology Recent Advances


Systemic Approaches In Bioinformatics And Computational Systems Biology Recent Advances
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Author : Lecca, Paola
language : en
Publisher: IGI Global
Release Date : 2011-12-31

Systemic Approaches In Bioinformatics And Computational Systems Biology Recent Advances written by Lecca, Paola and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-31 with Medical categories.


The convergence of biology and computer science was initially motivated by the need to organize and process a growing number of biological observations resulting from rapid advances in experimental techniques. Today, however, close collaboration between biologists, biochemists, medical researchers, and computer scientists has also generated remarkable benefits for the field of computer science. Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances presents new techniques that have resulted from the application of computer science methods to the organization and interpretation of biological data. The book covers three subject areas: bioinformatics, computational biology, and computational systems biology. It focuses on recent, systemic approaches in computer science and mathematics that have been used to model, simulate, and more generally, experiment with biological phenomena at any scale.



A First Course In Systems Biology


A First Course In Systems Biology
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Author : Eberhard Voit
language : en
Publisher: Garland Science
Release Date : 2017-09-05

A First Course In Systems Biology written by Eberhard Voit and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-05 with Computers categories.


A First Course in Systems Biology is an introduction for advanced undergraduate and graduate students to the growing field of systems biology. Its main focus is the development of computational models and their applications to diverse biological systems. The book begins with the fundamentals of modeling, then reviews features of the molecular inventories that bring biological systems to life and discusses case studies that represent some of the frontiers in systems biology and synthetic biology. In this way, it provides the reader with a comprehensive background and access to methods for executing standard systems biology tasks, understanding the modern literature, and launching into specialized courses or projects that address biological questions using theoretical and computational means. New topics in this edition include: default modules for model design, limit cycles and chaos, parameter estimation in Excel, model representations of gene regulation through transcription factors, derivation of the Michaelis-Menten rate law from the original conceptual model, different types of inhibition, hysteresis, a model of differentiation, system adaptation to persistent signals, nonlinear nullclines, PBPK models, and elementary modes. The format is a combination of instructional text and references to primary literature, complemented by sets of small-scale exercises that enable hands-on experience, and large-scale, often open-ended questions for further reflection.



An Introduction To Computational Systems Biology


An Introduction To Computational Systems Biology
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Author : Karthik Raman
language : en
Publisher: CRC Press
Release Date : 2021-05-30

An Introduction To Computational Systems Biology written by Karthik Raman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-30 with Computers categories.


Emphasises a hands-on approach to modelling Strong emphasis on coding and software tools for systems biology Covers the entire spectrum of modelling, from static networks, to dynamic models Thoughtful exercises to test and enable student understanding of concepts Current chapters on exciting new developments like whole-cell modelling and community modelling