Systems Biology Approaches Prevention Diagnosis And Understanding Mechanisms Of Complex Diseases
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Systems Biology Approaches Prevention Diagnosis And Understanding Mechanisms Of Complex Diseases
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Author : Sanket Joshi
language : en
Publisher: Springer Nature
Release Date : 2024-05-16
Systems Biology Approaches Prevention Diagnosis And Understanding Mechanisms Of Complex Diseases written by Sanket Joshi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-16 with Science categories.
This book examines the development and applications of system biology approaches for the prevention, diagnosis, and understanding of disease mechanisms. It explores the applications of system biology in infectious diseases, including host-pathogen interaction, and the identification of targets for new therapeutics and intervention strategies. It covers the use of system biology for understanding and treating metabolic disorders towards personalized and precision medicine. The book further discusses the systems biology approaches for understanding the mechanisms of tumor progression and designing more effective cancer therapies. The chapter also reviews the current strategies in autoimmune disease treatment and highlights the opportunity that systems biology represents for the development of better and safer treatments. Importantly, the book discusses the current state of the systems-level understanding of diseases and both the therapeutic and adverse mechanisms of drug actions usingsystem biology approaches. Cutting across the disciplines, this book is a valuable source for researchers in genetics, molecular biology, cell biology, microbiology, and biomedical sciences.
Multi Omics Technology In Human Health And Diseases
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Author : Muzafar A Macha
language : en
Publisher: Elsevier
Release Date : 2025-03-17
Multi Omics Technology In Human Health And Diseases written by Muzafar A Macha and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-17 with Science categories.
Multi-Omics Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omic provides a way forward in understanding complete disease etiology and prognosis. This unique book gives a comprehensive understanding of multi-omics technology and its applications in understanding complex human health and disease and not only introduces the technology, but also its use for biomarker identification, drug discovery, and disease prognostication. A comprehensive understanding of human health and diseases, particularly cancer, requires knowledge of molecular biomarkers at a multi-omics level, including genome, epigenome, transcriptome, proteome, and metabolome, which is meagerly available or highly lacking among the students and scientific researchers. This book covers all the aspects of multi-omics technology and how this technology can be implemented into scientific research and discovery.Multi-Omics Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omic is the first resource to present the latest information on currently utilized multi-omics technology for big data interpretation and their applications in understanding the complex human pathobiology. This is the perfect resource for researchers, academia, students, as well as the industrial audience. - Presents the most recent advancements in multiomics technology for elucidating complex human pathobiology. - Offers comprehensive insights into understanding disease etiology and prognosis. - Introduces the principles of multiomics technology and its applications in biomarker identification, drug discovery, and disease prognostication. - Explores the tools and methodologies for integrating and interpreting multiomics data sets. - Introduces multiomics databases and visualization web portals. - Provides up-to-date information on the role of multiomics technology in understanding intricate human pathobiology.
Challenges In Delivery Of Therapeutic Genomics And Proteomics
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Author : Aliasgar Shahiwala
language : en
Publisher: Academic Press
Release Date : 2025-03-06
Challenges In Delivery Of Therapeutic Genomics And Proteomics written by Aliasgar Shahiwala and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-06 with Medical categories.
Challenges in Delivery of Therapeutic Genomics and Proteomics, Second Edition is a complete reference on the biological principles involved in gene and protein delivery to cells and tissues. Highlighting the various chemical, physical, and biological approaches to protein and gene delivery, the book provides guidelines for pharmaceutical researchers in academia and corporate R&D. This new edition brings updates on the delivery of therapeutic proteomics and genomics in each chapter, and newly developed chapters on the regulatory aspects of related products, CRISPR/Cas9 gene editing, and computational tools in genomics and proteomics.After an overview of the barriers to genomics and proteomics delivery, the book dives into physical, chemical, and biological methods of gene delivery. Further chapters extensively discuss the delivery of proteins and therapeutic peptides through the respiratory, oral, parenteral, transdermal, topical, uterine, and rectal pathways. This book is the ideal reference for pharmaceutical scientists dealing with gene and protein/peptide delivery. Regulators and corporate researchers can also benefit from the wide coverage of delivery methods presented. - Includes genomics and proteomics delivery in one single volume - Highlights what's currently known and where further research is necessary - Covers topics from academic and corporate R&D perspectives - Includes new chapters on regulation, CRISPR/Cas9, and computational tools
Municipal Solid Waste Management And Recycling Technologies
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Author : Mehra, Ritika
language : en
Publisher: IGI Global
Release Date : 2024-08-28
Municipal Solid Waste Management And Recycling Technologies written by Mehra, Ritika and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-28 with Technology & Engineering categories.
The issue of overflowing landfills and environmental degradation caused by municipal solid waste is becoming increasingly pressing. Despite the importance of recycling, challenges such as contamination and the need for market demand for recycled materials persist. Addressing these challenges requires a comprehensive understanding of waste composition, innovative technologies, and effective policies. Municipal Solid Waste Management and Recycling Technologies serves as a solution, offering a deep dive into the complexities of municipal solid waste recycling and providing insights that can drive sustainable waste management practices. By delving into topics such as the role of education and awareness campaigns, technological advancements in waste sorting, and the economic aspects of recycling, this book equips readers with the knowledge needed to make a meaningful impact. It explores innovative recycling technologies, social and environmental implications, successful case studies, and strategies for reducing contamination in recycling processes. The book also highlights the importance of collaboration among researchers, policymakers, and stakeholders to implement effective waste management systems.
Computational And Systems Biology Methods For Elucidating Associations Between Cancer And Microbes
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Author : Lihong Peng
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-01
Computational And Systems Biology Methods For Elucidating Associations Between Cancer And Microbes written by Lihong Peng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-01 with Science categories.
Systems Biology And Omics Approaches To Understand Complex Diseases Biology
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Author : Amit Kumar Yadav
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-03
Systems Biology And Omics Approaches To Understand Complex Diseases Biology written by Amit Kumar Yadav and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-03 with Science categories.
Molecular Genetics And Emerging Therapies For Epithelial Ovarian Cancer Basic Research And Clinical Perspectives
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Author : Stergios Boussios
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-06
Molecular Genetics And Emerging Therapies For Epithelial Ovarian Cancer Basic Research And Clinical Perspectives written by Stergios Boussios and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-06 with Medical categories.
Epithelial ovarian cancer (EOC) is the most lethal gynecological disorder due to a lack of effective early detection strategies. Worldwide, approximately 230,000 women are diagnosed annually, whereas 150,000 die. It represents the seventh most commonly diagnosed cancer among women in the world with 5-year survival rate of 46%. More than one-fifth of EOC have been related to hereditary conditions. Considerable efforts have been made to implement screening of the general population to diagnose EOC early; nevertheless, this has been ineffective and there is no approved strategy. Nowadays, new approaches for early diagnosis and prevention based on molecular genomics are in development. Whole genome sequencing has established the potency of the somatic genome, characterised with diverse DNA repair deficiencies that can be used to stratify EOCs into distinct biological groups with predictive signatures of resistance or relapse. The incorporation of next-generation sequencing (NGS) into clinical practice remains challenging for two reasons. Firstly, the EOC risk is not clear for some of the included genes and secondly, the variant of uncertain significance rates increase as more genes are analyzed. Finally, beyond germline pathogenic variants, somatic mutations may also affect therapeutic choices, and as such upfront tumor sequencing may be equally important to NGS, particularly as we continue to challenge treatment paradigms in the first‐line management of EOC.
Volatile Organic Compound Analysis In Biomedical Diagnosis Applications
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Author : Raquel Cumeras
language : en
Publisher: CRC Press
Release Date : 2018-11-09
Volatile Organic Compound Analysis In Biomedical Diagnosis Applications written by Raquel Cumeras and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-09 with Science categories.
This volume presents a thought-provoking state-of-the-art picture of how volatile compounds are used in metabolomics, currently a hot topic in the metabolomics field. It provides a thorough description of what volatile organic compounds (VOCs) are, why they are important in biomedicine, and what the analytical platforms are used. It also looks at multivariate analysis and databases needs. Because VOCs are end-up compounds of metabolic processes, volatiles can be linked to different diseases or pathologies for both diagnosis and prognosis. The authors provide authoritative information and guidance on the analytical and statistical techniques used and how to identify, and they review the main current areas of application, which include breath metabolomics, cancer diagnosis, and microbial volatiles. Key Features: Presents a thorough overview of volatile research in biomedical applications Examines both gold standard techniques (metabolomics based) and artificial olfactory systems Reviews all aspects of volatile metabolites in biomedicine research, from origin to detection platforms Describes relevant diseases diagnosis and prognosis achievements, including cancer
Systems Biology And In Depth Applications For Unlocking Diseases
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Author : Babak Sokouti
language : en
Publisher: Elsevier
Release Date : 2024-11-05
Systems Biology And In Depth Applications For Unlocking Diseases written by Babak Sokouti and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-05 with Science categories.
Systems Biology and In-Depth Applications for Unlocking Diseases provides the essence of systems biology approaches in a practical manner illustrating the basic principles essential to develop and model in real life science applications. Methodologies covered show how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment.Systematically written in 4 parts, this book first provides an introduction and history of systems biology; second, it provides the tools and resources needed for the structure and function of biological systems; next, it provides the evidence of systems biology in action to better understand disease connections; and finally, it provides the extensions of systems biology in various scientific fields including pharmacology, immunology, vaccinology, neuroscience, virology, and medicine. Examples include big data techniques, scale networks, mathematical model development, and much more.This is the perfect reference to provide the fundamental base of knowledge needed for systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians, whether needed for immediate application or for building a comprehensive understanding of the field. - Provides detailed and comprehensive coverage of the field of systems biology - Delivers instruction on how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment - Makes effective steps towards personalized medicine in the treatment of disease - Explains effective disease treatment strategies at early diagnosis stages
Essential Concepts In Molecular Pathology
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Author : William B. Coleman
language : en
Publisher: Academic Press
Release Date : 2010-02-16
Essential Concepts In Molecular Pathology written by William B. Coleman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-16 with Science categories.
This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Each chapter ends with Key Summary Points and Suggested Readings