Systems Immunology
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Systems Immunology
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Author : Jayajit Das
language : en
Publisher: CRC Press
Release Date : 2018-09-03
Systems Immunology written by Jayajit Das and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Science categories.
"Taken together, the body of information contained in this book provides readers with a bird’s-eye view of different aspects of exciting work at the convergence of disciplines that will ultimately lead to a future where we understand how immunity is regulated, and how we can harness this knowledge toward practical ends that reduce human suffering. I commend the editors for putting this volume together." –Arup K. Chakraborty, Robert T. Haslam Professor of Chemical Engineering, and Professor of Physics, Chemistry, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, USA New experimental techniques in immunology have produced large and complex data sets that require quantitative modeling for analysis. This book provides a complete overview of computational immunology, from basic concepts to mathematical modeling at the single molecule, cellular, organism, and population levels. It showcases modern mechanistic models and their use in making predictions, designing experiments, and elucidating underlying biochemical processes. It begins with an introduction to data analysis, approximations, and assumptions used in model building. Core chapters address models and methods for studying immune responses, with fundamental concepts clearly defined. Readers from immunology, quantitative biology, and applied physics will benefit from the following: Fundamental principles of computational immunology and modern quantitative methods for studying immune response at the single molecule, cellular, organism, and population levels. An overview of basic concepts in modeling and data analysis. Coverage of topics where mechanistic modeling has contributed substantially to current understanding. Discussion of genetic diversity of the immune system, cell signaling in the immune system, immune response at the cell population scale, and ecology of host-pathogen interactions.
Systems Immunology And Infection Microbiology
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Author : Bor-Sen Chen
language : en
Publisher: Academic Press
Release Date : 2021-03-15
Systems Immunology And Infection Microbiology written by Bor-Sen Chen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-15 with Science categories.
Systems Immunology and Infection Microbiology provides a large amount of biological system models, diagrams and flowcharts to illustrate the development procedure to understand the results of the systems immunology and infection microbiology. The results are not only remarkable, but also revolutionary in immunology and infection microbiology and can be also applied to systems drug design in infectious diseases.The book is divided into six parts. The first one discusses systems immunology; the second, systems infection microbiology; the third, systematic inflammation and immune responses in restoration and regeneration process; the forth introduces systems innate and adaptive immunity in infection process; systematic genetic and epigenetic pathogenic/defensive mechanism during bacterial infection on human cells is introduced in the fifth part; and the sixth and final part discusses systematic genetic and epigenetic pathogenic/defensive mechanism during the viral infection on human cells.This book provides a new big data-driven and systems-driven systems immunology and infection microbiology to researchers applying systems biology and bioinformatics in their works, and to several members of biomedical field who are interested to learn more about those approaches. Encompasses one applicable example in every chapter to illustrate the solution procedure from big data mining, network modelling, host/pathogen cross-talk detection, drug target identification and systems drug design Presents flowcharts to represent the development procedure of systematic immunology and infection in a very clear format Contains 100 colour diagrams to help readers understand the related biological networks, their corresponding mechanisms and significant network biomarkers for therapeutic drug design
Immuno Systems Biology
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Author : Kumar Selvarajoo
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-01
Immuno Systems Biology written by Kumar Selvarajoo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-01 with Medical categories.
Immuno Systems Biology aims to study the immune system in the more integrated manner on how cells and molecules participate at different system levels to the immune function. Through this book Kumar Selvarajoo introduces to physicists, chemists, computer scientists, biologists and immunologists the idea of an integrated approach to the understanding of mammalian immune system. Geared towards a researcher with limited immunological and computational analytical experience, the book provides a broad overview to the subject and some instruction in basic computational, theoretical and experimental approaches. The book links complex immunological processes with computational analysis and emphasizes the importance of immunology to the mammalian system.
Single Cell Sequencing And Systems Immunology
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Author : Xiangdong Wang
language : en
Publisher: Springer
Release Date : 2015-03-27
Single Cell Sequencing And Systems Immunology written by Xiangdong Wang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-27 with Medical categories.
The volume focuses on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding the molecular mechanisms of systems immunology. Based on the author’s personal experience, it provides revealing insights into the potential applications, significance, workflow, comparison, future perspectives and challenges of single-cell sequencing for identifying and developing disease-specific biomarkers in order to understand the biological function, activation and dysfunction of single cells and lymphocytes and to explore their functional roles and responses to therapies. It also provides detailed information on individual subgroups of lymphocytes, including cell characters, function, surface markers, receptor function, intracellular signals and pathways, production of inflammatory mediators, nuclear receptors and factors, omics, sequencing, disease-specific biomarkers, bioinformatics, networks and dynamic networks, their role in disease and future prospects. Dr. Xiangdong Wang is a Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Director of the Biomedical Research Center of Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China.
Systems Biology In Cancer Immunotherapy
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Author : Mahbuba Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2016-06-07
Systems Biology In Cancer Immunotherapy written by Mahbuba Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-07 with Medical categories.
Over the past decades, systems biology approaches have been applied in different areas of life science research including oncology. Researchers now understand the hallmarks of cancer cells such as abnormal cell growth, inflammation, dysregulated metabolic pathways and drug resistance properties at a molecular level. Systems biology approaches have enabled researchers to investigate cancer immunology by identifying cancer related biomarkers on immune cells, and to study the effect of different therapies in tissue cultures and mouse models. Systems Biology in Cancer Immunotherapy explains the scope of systems biology in understanding the immune response to neoplasms. The book introduces readers to the concepts crucial to cancer immunology before delving into the applied systems biology topics such as the metabolic pathways in cancer cells, the biomolecular roles of signal transduction molecules and their respective biochemical pathways ad cancer immunotherapy. A brief conclusion at the end also provides some information from a clinical and commercial perspective on cancer immunotherapy. This volume is intended as an introductory reference for life science and medical students, researchers and academics interested in the application of systems biology to the immune system in oncology research and chemotherapy practice.
Integrative Computational Systems Biology Approaches In Immunology And Medicine
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Author : Lars Kaderali
language : en
Publisher: Frontiers Media SA
Release Date : 2019-04-09
Integrative Computational Systems Biology Approaches In Immunology And Medicine written by Lars Kaderali and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-09 with categories.
Advances In Systems Immunology And Cancer
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Author : Masaru Tomita
language : en
Publisher: Frontiers E-books
Release Date : 2014-12-17
Advances In Systems Immunology And Cancer written by Masaru Tomita and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-17 with Biology (General) categories.
Immunology A Systems Biology Perspective
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Author : Katie Murphy
language : en
Publisher: States Academic Press
Release Date : 2023-09-26
Immunology A Systems Biology Perspective written by Katie Murphy and has been published by States Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-26 with Medical categories.
The branch of biology and medicine that focuses on the study of immune systems in all organisms is termed as immunology. The basic purpose of studying the immune systems is to chart, measure and describing the functioning of the immune system in the state of health and disease. The study of immunology has a wide range of applications in different fields of medicine such as bacteriology, parasitology, psychiatry, oncology and organ transplantation. Immunological disorders can lead to immunodeficiency and autoimmune diseases. Immunodeficiency is a condition in which the organism's ability to fight infectious diseases and cancer is absent or is highly compromised. Autoimmune diseases are a result of abnormal immune response to a functioning part of the body. This book contains some path-breaking studies in the field of immunology. From theories to research to practical applications, case studies related to all contemporary topics of relevance to this field have been included herein. The book aims to serve as a resource guide for students and experts alike and contribute to the growth of the discipline.
Frontiers In Cancer Immunology Systems Biology In Cancer Immunotherapy
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Author : Mahbuba Rahman
language : en
Publisher: Frontiers in Cancer Immunology
Release Date : 2016-06-07
Frontiers In Cancer Immunology Systems Biology In Cancer Immunotherapy written by Mahbuba Rahman and has been published by Frontiers in Cancer Immunology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-07 with Medical categories.
Over the past decades, systems biology approaches have been applied in different areas of life science research including oncology. Researchers now understand the hallmarks of cancer cells such as abnormal cell growth, inflammation, dysregulated metabolic pathways and drug resistance properties at a molecular level. Systems biology approaches have enabled researchers to investigate cancer immunology by identifying cancer related biomarkers on immune cells, and to study the effect of different therapies in tissue cultures and mouse models. Systems Biology in Cancer Immunotherapy explains the scope of systems biology in understanding the immune response to neoplasms. The book introduces readers to the concepts crucial to cancer immunology before delving into the applied systems biology topics such as the metabolic pathways in cancer cells, the biomolecular roles of signal transduction molecules and immunotherapy. A brief conclusion at the end also provides some information from a clinical and commercial perspective on cancer immunotherapy. This volume is intended as an introductory reference for life science and medical students, researchers and academics interested in the application of systems biology to the immune system in cancer patients.
Systems Immunology Landscaping Immune Regulatory Networks
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Author : Aridaman Pandit
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-31
Systems Immunology Landscaping Immune Regulatory Networks written by Aridaman Pandit and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Medical categories.