Systems Medicine For Human Spaceflight
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Systems Medicine For Human Spaceflight
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Author : Mark J Shelhamer
language : en
Publisher: World Scientific
Release Date : 2024-03-19
Systems Medicine For Human Spaceflight written by Mark J Shelhamer and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-19 with Medical categories.
This edited volume makes the case that a systems approach is needed for long-term spaceflight missions. Due to distance from Earth and the impossibility of resupply or rapid return, these flights will entail unprecedented autonomy on the part of the crew. This autonomy includes the need for local clinical decision support and other assistance with urgent medical concerns. The advantage of a systems approach to medical needs in human spaceflight is that it enables a systematic and repeatable methodology for identifying and developing the individual pieces of the spacecraft systems based on the human system needs that are unique to that problem and environment.The book begins by introducing a systems basis for thinking about humans in space. It describes existing models and paradigms of systems medicine, as well as the tools and analytical approaches involved. A tantalizing peek at preliminary applications of systems medicine in NASA is provided. As systems in human spaceflight continue to evolve for the foreseeable future, it is argued that a systems approach will help to ensure that the evolution of the relevant sub-systems is centered on optimal human-system function across the unique spaceflight needs of the developing customer base. The discussions on balancing the needs of the mission versus the maintenance of crew health, medical risk and liability for commercial spaceflights, and the need to anticipate what the next medical issues might be, will hopefully leave readers cautiously optimistic about this new frontier of applied science.
Principles Of Clinical Medicine For Space Flight
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Author : Michael R. Barratt
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-03-20
Principles Of Clinical Medicine For Space Flight written by Michael R. Barratt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-20 with Medical categories.
Over the years, a large body of knowledge has developed regarding the ways in which space flight affects the health of the personnel involved. Now, for the first time, this clinical knowledge on how to diagnose and treat conditions that either develop during a mission or because of a mission has been compiled by Drs. Michael Barratt and Sam L. Pool of the NASA/Johnson Space Center. Complete with detailed information on the physiological and psychological affects of space flight as well as how to diagnose and treat everything from dental concerns to decompression to dermatological problems encountered, this text is a must have for all those associated with aerospace medicine.
Fundamentals Of Space Medicine
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Author : Gilles Clément
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-07-07
Fundamentals Of Space Medicine written by Gilles Clément and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-07 with Science categories.
Investigations in space have led to fundamental discoveries of the human body to the space environment. Gilles Clément has conducted extensive research in this field. This readable text presents the findings from the life science experiments conducted during and after space missions. About 1200 human space flights have been completed to date, including more than 500 astronauts from various countries, for a combined total presence in space of about 90 years. The first edition of this title was published in 2005 (written in 2003 – 2004), and new data is now available from crewmembers participating in long-duration flights on board the International Space Station (ISS). The number of astronauts who have spent six months in orbit has doubled since 2004. On board the ISS, the astronauts use newly developed pharmaceutical countermeasure for bone loss (such as biophosphonates) and state-of-the-art exercise resistive devices against muscle atrophy and cardiovascular deterioration. The ISS life support systems now use advanced closed-loop systems for meeting the needs of a 6-person crew, including recycling urine to water. Some of these new technologies have potential spin-offs for medical (i.e., sedentary life style, obesity) and environmental issues here on Earth. And finally, there are new space research opportunities with the Orion space vehicle that will soon replace the Space Shuttle, the Moon, and Mars space exploration program that is slowly but surely taking shape, and the space tourism sector that has become a reality. The focus on this edition is the ISS, Orion and planetary exploration, and space tourism. This edition also includes more than 20% new material, along with photographs, data, and video clips for Springer Extras!
The Human Factor
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Author : John A. S. Pitts
language : en
Publisher:
Release Date : 1985
The Human Factor written by John A. S. Pitts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Space biology categories.
Humans In Spaceflight
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Author : Arnauld E. Nicogossian
language : en
Publisher: AIAA
Release Date : 1993
Humans In Spaceflight written by Arnauld E. Nicogossian and has been published by AIAA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
This third volume in the Space Biology and Medicine series addresses the major issues concerning humans in space, such as metabolism, the immune system, neurosensory and sensory motor functions, gravitational biology, radiation, pharmacokinetics and much more. It is composed of two parts: Effects of Microgravity and Effects of Other Spaceflight Factors. As in the previous two volumes, the contributing authors are experts in their respective fields.
Biomedical Research And Computer Application In Manned Space Flight
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Author : United States. National Aeronautics and Space Administration. Technology Utilization Office
language : en
Publisher:
Release Date : 1971
Biomedical Research And Computer Application In Manned Space Flight written by United States. National Aeronautics and Space Administration. Technology Utilization Office and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Medicine categories.
"Technology Utilization Program designed to transfer technological developments that may have useful commereial applications. From NASA laboratories and contractors, aeronautics and space-related technology is gathered and evaluated. Items which have potential industrial use are made generally available. This survey of computer uses in the field of medicine is one of a series of NASA publications that presents information of direct or indirect interest to the non-aerospace community. ... This report summarizes the areas of medicine in which computers can be employed and examines in detail several cases where computers have been applied in connection with the medical aspects of NASA's manned space flight program. Treated are such problems as those of automated medical data storage and retrieval systems, continuous monitoring and interpretation of electrocardiograms, and computer-aided medical diagnosis. The approach is cautious throughout, with the emphasis almost constantly on ways to permit the computer to perform various clerical functions while leaving critical decisions to a human monitor."--Foreword.
Effect Of Spaceflight And Spaceflight Analogue Culture On Human And Microbial Cells
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Author : Cheryl A. Nickerson
language : en
Publisher: Springer
Release Date : 2016-05-21
Effect Of Spaceflight And Spaceflight Analogue Culture On Human And Microbial Cells written by Cheryl A. Nickerson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-21 with Medical categories.
Many breakthroughs in biological research and translational healthcare advancements have been achieved by studying the response of biological systems to extreme environments. The spaceflight platform provides a unique environment where researchers can explore fundamental questions into cellular and molecular response mechanisms to unveil novel insight into human health and disease. Since the physical force of gravity has shaped the architecture of all biological systems on our planet, spaceflight provides the opportunity to see life in a new adaptational mode - in response to reduced gravity. This enables investigations into the effects of the microgravity environment and associated changes in mechanical forces on mammalian cells/tissues and microbial pathogens, to bring novel insight into disease mechanisms, which are not discernable using conventional experimental approaches. Research using spaceflight platforms represents a paradigm shift in how we observe life processes and is on the leading edge of research discoveries into cellular and molecular mechanisms of health and disease. By incorporating the views of leading authors, this book highlights landmark discoveries and advances in mammalian cellular and microbiology research in both true spaceflight and ground-based spaceflight analogue environments for scientists and students alike who are interested in the influence of physical forces on mammalian and microbial cells, how this impacts transition between normal homeostasis and disease, and basic mechanisms of adaptation to low gravity environments. To provide a thorough understanding of this research, this book covers a range of topics including: (i) description the physical forces interacting with cells in microgravity and microgravity analogue environments, (ii) how alterations in these cellular forces impact human physiology, specifically immune function, (iii) use of these environments to develop organotypic three-dimensional (3-D) tissue culture models as predictive human surrogates for organogenesis and disease research, and (iv) microbial pathogen responses to culture in these environments, focusing on infectious disease Collectively, this information reflects a critical step in preparation for long-duration human space exploration, advances our knowledge of basic biological processes and mechanisms important to understand normal function and disease, and may lead to new strategies for treatment and prevention.
Review Of Nasa S Biomedical Research Program
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2000-08-09
Review Of Nasa S Biomedical Research Program written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-08-09 with Science categories.
The 1998 Committee on Space Biology and Medicine (CSBM) report A Strategy for Research in Space Biology and Medicine in the New Century assessed the known and potential effects of spaceflight on biological systems in general and on human physiology, behavior, and performance in particular, and recommended directions for research sponsored over the next decade by the National Aeronautics and Space Administration (NASA). The present follow-up report reviews specifically the overall content of the biomedical research programs supported by NASA in order to assess the extent to which current programs are consistent with recommendations of the Strategy report for biomedical research activities. In general, NASA programs concerned with fundamental gravitational biology are not considered here. The committee also notes that this report does not include an evaluation of NASA's response to the Strategy report, which had only recently been released at the initiation of this study. Review of NASA's Biomedical Research Program summarizes the committee's findings from its review of (1) NASA's biomedical research and (2) programmatic issues described in the Strategy report that are relevant to NASA's ability to implement research recommendations.
Nasa Human Spaceflight Astronaut Health Research For Exploration And Manned Mars Missions Risk Report Wsn 03 Intervertebral Disc Damage Altered Immune Response Cardiac Rhythm Osteoporosis
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Author : National Aeronautics and Space Administration (NASA)
language : en
Publisher:
Release Date : 2017-12-05
Nasa Human Spaceflight Astronaut Health Research For Exploration And Manned Mars Missions Risk Report Wsn 03 Intervertebral Disc Damage Altered Immune Response Cardiac Rhythm Osteoporosis written by National Aeronautics and Space Administration (NASA) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-05 with categories.
This series of reports deals with ongoing research by NASA into a risk reduction strategy for human space exploration and planned manned missions to Mars. Each report deals with a unique aspect of the human research needed to pursue long-duration missions. Many of the reports contain exclusive details about medical events impacting astronauts and cosmonauts on earlier flights, including Mir, Space Shuttle, and ISS Space Station missions. Each risk Evidence Report contains a narrative discussion of the risk and its supporting evidence. All cited publicly-available references are listed at the end of the report. In addition, data that are significant or pivotal are summarized in text, tables, and charts in sufficient detail to allow the reader to critique the data and draw conclusions. The authors also indicate whether the data are from human, animal, or tissue, cellular, or molecular studies. The reports discuss evidence from both spaceflight (including biomedical research, Medical Requirements Integration Document [MRID] data, and operational performance or clinical observations) and ground (including space analog research and non-space analog biomedical or clinical research) research. When providing evidence from ground-based studies, authors discuss why these results are likely to be applicable in the space environment, offering any available validation information for the use of these ground-based systems. Reports included in this compilation: Evidence Book: Risk of Intervertebral Disc Damage * Evidence Report: Risk of Crew Adverse Health Event Due to Altered Immune Response * Evidence Based Review: Risk of Cardiac Rhythm Problems during Space Flight * Evidence Book: Risk of Accelerated Osteoporosis There is a large body of evidence associated with immune dysregulation and spaceflight. However, current studies onboard the International Space Station (ISS) that are defining space normal for the human immune system remain insufficient to determine clinical risk during exploration space missions. In particular, more in-flight studies are needed using human subjects. Crew health and performance is critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) investigates and mitigates the highest risks to human health and performance, providing essential countermeasures and technologies for human space exploration. Risks include physiological and performance effects from hazards such as radiation, altered gravity, and hostile environments, as well as unique challenges in medical support, human factors, and behavioral health support. The HRP utilizes an Integrated Research Plan (IRP) to identify the approach and research activities planned to address these risks, which are assigned to specific Elements within the program. The HRP utilizes various research platforms to conduct research. Ground research occurs in laboratories and analogs that mimic a portion of the spaceflight environment. In addition, the International Space Station (ISS) is used to conduct research requiring the unique environment of space.
Humans In Spaceflight
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Author : Arnauld E. Nicogossian
language : en
Publisher: AIAA (American Institute of Aeronautics & Astronautics)
Release Date : 1993
Humans In Spaceflight written by Arnauld E. Nicogossian and has been published by AIAA (American Institute of Aeronautics & Astronautics) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
This third volume in the Space Biology and Medicine series addresses the major issues concerning humans in space, such as metabolism, the immune system, neurosensory and sensory motor functions, gravitational biology, radiation, pharmacokinetics and much more. It is composed of two parts: Effects of Microgravity and Effects of Other Spaceflight Factors. As in the previous two volumes, the contributing authors are experts in their respective fields.