Target Organ Pathology
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Target Organ Pathology
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Author : J. Turton
language : en
Publisher: CRC Press
Release Date : 1997-10-06
Target Organ Pathology written by J. Turton and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-06 with Medical categories.
The major organs of the body are targets for chemically-induced effects in animals and humans. This book reviews the mechanisms of these toxic effects and the structure/functional changes which occur in the target organ tissues as a result.
Pathology For Toxicologists
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Author : Elizabeth McInnes
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-16
Pathology For Toxicologists written by Elizabeth McInnes and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-16 with Science categories.
Non-pathologists, such as toxicologists and study personnel, can find it difficult to understand the data they receive from pathologists. Toxicological pathologists write long, detailed and highly technical reports. Study personnel are under daily pressure to decide whether lesions described in pathology reports are treatment-related and thus important to the pharmaceutical company or whether the lesions are background changes and thus of little significance. Written by experienced toxicological pathologists, Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel serves to bridge the gap in the understanding of pathology data, enabling non-pathologists to more easily comprehend pathology reports, better integrate pathology data into final study reports and ask pathologists relevant questions about the test compound. This succinct, fully referenced, full colour book is suitable for toxicologists at all stages of their training or career who want to know more about the pathology encountered in laboratory animals used in safety studies. Key features include important chapters on spontaneous and target organ lesions in rats, mice, non-human primates, mini pigs, rabbits and beagle dogs as well as information on general pathology, macroscopic target organ lesions, ancillary pathology techniques, haematology, biochemistry and adversity. Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel includes: Colour diagrams explaining how lesions are caused by either external compounds or spontaneously The anatomic variations and background lesions of laboratory animals Advice on sampling tissues, necropsy, ancillary pathology techniques and recording data A chapter on the haematology and biochemistry of laboratory animals Full colour photographs of common macroscopic lesions encountered in laboratory animals A comprehensive glossary
Target Organ Pathology
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Author : J. Turton
language : en
Publisher: CRC Press
Release Date : 1997-10-06
Target Organ Pathology written by J. Turton and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-06 with Medical categories.
The major organs of the body are targets for chemically-induced effects in animals and humans. This book reviews the mechanisms of these toxic effects and the structure/functional changes which occur in the target organ tissues as a result.
Tatget Organ Pathology
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Author : J. A. Turton
language : en
Publisher:
Release Date : 1997
Tatget Organ Pathology written by J. A. Turton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with categories.
The major organs of the body are targets for chemically-induced effects in animals and humans. This book reviews the mechanisms of these toxic effects and the structure/functional changes which occur in the target organ tissues as a results of exposure to toxicants including drugs, agrochemicals, industrial chemicals, radiation and heat. The organs of the body covered include the liver, lymphatic system, cardiovascular system, respiratory tract, lungs, skeleton, skin, central nervous system, endocrine system and the reproductive system.
Target Organ Toxicology In Caenorhabditis Elegans
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Author : Dayong Wang
language : en
Publisher: Springer
Release Date : 2019-02-12
Target Organ Toxicology In Caenorhabditis Elegans written by Dayong Wang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-12 with Medical categories.
This book introduces readers to intestinal and epidermal barriers, and to toxicity induction of environmental toxicants or stresses in the intestine, epidermis, neurons, muscle, and reproductive organs in Caenorhabditis elegans. In addition, it discusses the protective responses of various organs and nematodes’ avoidance behaviour with regard to environmental toxicants or stresses. The intestinal, epidermal, neuronal, and germline signalling pathways required for the regulation of toxicity of environmental toxicants or stresses are also introduced and discussed. As a classic model animal with well-described genetic and developmental backgrounds, the nematode Caenorhabditis elegans has been successfully and widely used in both toxicity assessments and toxicological studies on various environmental toxicants and stresses. Once exposure to certain environmental toxicants has occurred, the toxicants can enter into the primary targeted organs (such as intestinal cells), and even be translocated into secondary targeted organs (such as reproductive organs and neurons). Based on related available data, this book provides a systematic understanding of target organ toxicology in C. elegans.
Toxicology Of The Liver
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Author : Gabriel L Plaa
language : en
Publisher: CRC Press
Release Date : 1998-02-27
Toxicology Of The Liver written by Gabriel L Plaa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-02-27 with Medical categories.
This second edition looks at the physiologic, biochemical, and morphologic characteristics of hepatotoxicity and includes an analysis of techniques in molecular biology and immunochemistry, among others contributing to the growth in understanding of the toxic events involved. It focuses on clinical characterization of chemical hepatotoxicity, micro
Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 1 Principles And Practice Of Toxicologic Pathology
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Author : Wanda M. Haschek-Hock
language : en
Publisher: Academic Press
Release Date : 2021-10-20
Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 1 Principles And Practice Of Toxicologic Pathology written by Wanda M. Haschek-Hock and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-20 with Medical categories.
Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations