Target Organ Pathology
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Target Organ Pathology
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Author : J. Turton
language : en
Publisher: CRC Press
Release Date : 1997-10-06
Target Organ Pathology written by J. Turton and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-06 with Medical categories.
The major organs of the body are targets for chemically-induced effects in animals and humans. This book reviews the mechanisms of these toxic effects and the structure/functional changes which occur in the target organ tissues as a result.
Target Organ Pathology
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Author : J. Turton
language : en
Publisher: CRC Press
Release Date : 1997-10-06
Target Organ Pathology written by J. Turton and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-06 with Medical categories.
The major organs of the body are targets for chemically-induced effects in animals and humans. This book reviews the mechanisms of these toxic effects and the structure/functional changes which occur in the target organ tissues as a result.
Pathology For Toxicologists
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Author : Elizabeth McInnes
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-16
Pathology For Toxicologists written by Elizabeth McInnes and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-16 with Science categories.
Non-pathologists, such as toxicologists and study personnel, can find it difficult to understand the data they receive from pathologists. Toxicological pathologists write long, detailed and highly technical reports. Study personnel are under daily pressure to decide whether lesions described in pathology reports are treatment-related and thus important to the pharmaceutical company or whether the lesions are background changes and thus of little significance. Written by experienced toxicological pathologists, Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel serves to bridge the gap in the understanding of pathology data, enabling non-pathologists to more easily comprehend pathology reports, better integrate pathology data into final study reports and ask pathologists relevant questions about the test compound. This succinct, fully referenced, full colour book is suitable for toxicologists at all stages of their training or career who want to know more about the pathology encountered in laboratory animals used in safety studies. Key features include important chapters on spontaneous and target organ lesions in rats, mice, non-human primates, mini pigs, rabbits and beagle dogs as well as information on general pathology, macroscopic target organ lesions, ancillary pathology techniques, haematology, biochemistry and adversity. Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel includes: Colour diagrams explaining how lesions are caused by either external compounds or spontaneously The anatomic variations and background lesions of laboratory animals Advice on sampling tissues, necropsy, ancillary pathology techniques and recording data A chapter on the haematology and biochemistry of laboratory animals Full colour photographs of common macroscopic lesions encountered in laboratory animals A comprehensive glossary
Radiopathology Of Organs And Tissues
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Author : Eberhard Scherer
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Radiopathology Of Organs And Tissues written by Eberhard Scherer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The biologic effects of radiation on normal tissues and tumors represent a complex area for investigation. These effects are of far-reaching consequence to the diagnostic radiologist and the radiation oncologist having a significant impact not only in concepts relative to radiation protection but also in concepts relative to tumor biology and its response to radiation injury. The volume edited by SCHERER, STREFFER, and TROTT represents an extension of basic radiation biology data into the effects of radiation in producing pathology in organs and tissues. The data presented by the multiple authors involved in this text cover essentially all tissues in the body with specific definition of radiopathology changes and their impact on clinical care of the patient. This volume represents an important and significant contribution toward a better understanding of these effects and the pathology produced by radiations. L. W. BRADY H.-P. HEILMANN F. HEUCK M. W. DONNER Philadelphia Hamburg Stuttgart Baltimore Preface This book represents an attempt to describe the clinical radiobiology of complications arising in different organs after radiotherapy of cancer patients. Since by their very nature malignant tumors infiltrate the organ in which they have arisen and the neighboring tissues, curative radiotherapy requires the planned irradiation of considerable amounts of healthy but potentially or microscopically involved normal tissues and organs with the full target dose. This may lead to early or late normal tissue radiation injury.
Target Organ Toxicity
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Author : Cohen, James Rab
language : en
Publisher: CRC-Press
Release Date : 2000-12-01
Target Organ Toxicity written by Cohen, James Rab and has been published by CRC-Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-12-01 with Medical categories.
This two-volume set provides essential information on the general principles of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modification and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharmacologists, biochemists, and environmental toxicologists.
Essentials Of Pathology For Toxicologists
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Author : Paul Grasso
language : en
Publisher: CRC Press
Release Date : 2002-03-21
Essentials Of Pathology For Toxicologists written by Paul Grasso and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03-21 with Medical categories.
Currently, the only pathology books available to pathologists are large tomes written for medical and veterinary students. Essentials of Pathology for Toxicologists is an outstanding starting point for those coming to grips with the fundamentals such as cell damage and cell death. It includes discussion on inflammation, hypertrophy, neoplasia, thro
Essentials Of Pathology For Toxicologists
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Author : Paul Grasso
language : en
Publisher: CRC Press
Release Date : 2002-03-21
Essentials Of Pathology For Toxicologists written by Paul Grasso and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03-21 with Medical categories.
Currently, the only pathology books available to pathologists are large tomes written for medical and veterinary students. Essentials of Pathology for Toxicologists is an outstanding starting point for those coming to grips with the fundamentals such as cell damage and cell death. It includes discussion on inflammation, hypertrophy, neoplasia, thrombosis, restoration and repair, and immune disease. It also contains guidelines for understanding pathologists' reports and their working methods - written specifically for the toxicologist. A thorough hematology glossary also helps toxicologists familiarize themselves with key pathology terms.
Regulatory Toxicology
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Author : Franz-Xaver Reichl
language : en
Publisher: Springer
Release Date : 2014-03-27
Regulatory Toxicology written by Franz-Xaver Reichl and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-27 with Medical categories.
This book will be written by experts for professionals, scientists and all those involved in toxicological data generation and decision-making. It is the updated and expanded version of a monograph published in German in 2004. Chemical safety is regulated on various levels including production, storage, transport, handling, disposal or labelling. This book deals comprehensively with the safety-ensuring methods and concepts employed by regulatory agencies, industry and academics. Toxicologists use experimental and scientific approaches for data collection, e.g. about chemical hazards, physicochemical features or toxicokinetics. The respective experimental methods are described in the book. Toxicologists also deal with much insecurity in the exposure and effect scenarios during risk assessment. To overcome these, they have different extrapolation methods and estimation procedures at their disposal. The book describes these methods in an accessible manner. Differing concepts from one regulation area to another are also covered. Reasons and consequences become evident when reading the book. Altogether, the book Regulatory Toxicology will serve as an excellent reference.
Toxicology Of The Liver
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Author : Gabriel L. Plaa
language : en
Publisher:
Release Date : 1982
Toxicology Of The Liver written by Gabriel L. Plaa and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.
Target Organ Toxicity In Marine And Freshwater Teleosts
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Author : Daniel Schlenk
language : en
Publisher: CRC Press
Release Date : 2017-03-27
Target Organ Toxicity In Marine And Freshwater Teleosts written by Daniel Schlenk and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-27 with Medical categories.
Addressing the numerous gaps in current information, Target Organ Toxicology in Marine and Freshwater Teleosts is an essential resource for researchers and professionals in aquatic toxicology and environmental risk assessment. All the chapters are written by researchers who are internationally recognised for their work in mechanistic aspects of aquatic toxicology. Each chapter focuses on a specific target organ or physiological system and describes how various agents disrupt the normal physiological system and processes. This volume is devoted to specific organs with coverage of the gill, kidney, skin, liver and gut. The companion volume, Systems, provides coverage of toxic effects in the central nervous, immune, neurobehavioural and reproductive systems as well as describing general mechanisms of toxicity.
