Targeting Key Cellular Signaling Network For Cancer Chemotherapy And Immunotherapy
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Targeting Key Cellular Signaling Network For Cancer Chemotherapy And Immunotherapy
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Author : Bo Zhai
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-04
Targeting Key Cellular Signaling Network For Cancer Chemotherapy And Immunotherapy written by Bo Zhai and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-04 with Medical categories.
The cellular signaling network refers to the complex system formed by the interactions between various signaling molecules and receptors within and between cells. It consists of multiple signaling pathways that mediate intricate cellular interactions both internally and externally. The development of cancer is closely associated with the intricate signaling transduction network within cells, where multiple signaling pathways are interconnected and collectively regulate the biological phenotypes of tumor cells.
Life Over Cancer
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Author : Keith Block
language : en
Publisher: Bantam
Release Date : 2009-04-21
Life Over Cancer written by Keith Block and has been published by Bantam this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-21 with Health & Fitness categories.
Dr. Keith Block is at the global vanguard of innovative cancer care. As medical director of the Block Center for Integrative Cancer Treatment in Evanston, Illinois, he has treated thousands of patients who have lived long, full lives beyond their original prognoses. Now he has distilled almost thirty years of experience into the first book that gives patients a systematic, research-based plan for developing the physical and emotional vitality they need to meet the demands of treatment and recovery. Based on a profound understanding of how body and mind can work together to defeat disease, this groundbreaking book offers: • Innovative approaches to conventional treatments, such as “chronotherapy”–chemotherapy timed to patients’ unique circadian rhythms for enhanced effectiveness and reduced toxicity • Dietary choices that make the biochemical environment hostile to cancer growth and recurrence, and strengthen the immune system’s ability to attack remaining cancer cells • Precise supplement protocols to tame treatment side effects, relieve disease-related symptoms, and modify processes like inflammation and glycemia that can fuel cancer if left untreated • A new paradigm for exercise and stress reduction that restores your strength, reduces anxiety and depression, and supports the body’s own ability to heal • A complete program for remission maintenance–a proactive plan to make sure the cancer never returns Also included are “quick-start” maps to help you find the information you need right now and many case histories that will support and inspire you. Encouraging, compassionate, and authoritative, Life over Cancer is the guide patients everywhere have been waiting for.
Cancer Immunotherapy Immuno Monitoring Mechanism Treatment Diagnosis And Emerging Tools
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Author : Chao Ma
language : en
Publisher: Frontiers E-books
Release Date : 2014-12-16
Cancer Immunotherapy Immuno Monitoring Mechanism Treatment Diagnosis And Emerging Tools written by Chao Ma and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-16 with Cancer categories.
In the past decade, significant progresses have taken place in the field of cancer immunotherapy. Tumor-targeting immunotherapies are being developed for most human cancers, including melanoma, prostate cancer, glioblastoma, sarcoma, lung carcinoma and hepatocellular carcinoma. The FDA has approved multiple molecular immunotherapeutics, such as Ipilimumab; cellular immunotherapies (e.g. adoptive cell transfer) are being tested in phase II/III clinical trials. Immunotherapetics has evolved into a sophisticated field: Multimodal therapeutic regimens are administrated to induce focused responses, curtail side- effects and improve therapeutic efficacy. The lack of effective clinical assessment tools remains a major challenge. Because of the intricacy of antitumor response, it is essential to scrutinize individual tumor-targeting immune cells and their functions at the finest details – molecules. In this regard, flow cytometry analysis modernized hematology and allows characterization of surface molecular signature on individual cells. More recently, microchip technologies and new variations of cytometry have enormously expanded the spectrum, throughout and multiplexity of single cell analysis. Nowadays, tens of millions of readouts can be generated through the course of a cancer immunotherapy to monitor the abundance, phenotype and a myriad of effector functions of single immune cells. At the same time, big data analytics and data mining methodologies have been adapted to achieve sensible diagnostic interpretations. Such a marriage of technology and analytics opens the door for informative point-of-care assessment of therapeutic efficacy and ensures timely therapeutic decisions. The new generation of personalized clinical diagnostics will revolutionize healthcare in the years to come.
Cancer Immunotherapy
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Author : George C. Prendergast
language : en
Publisher: Elsevier
Release Date : 2011-04-28
Cancer Immunotherapy written by George C. Prendergast and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-28 with Medical categories.
There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease.* Offers a synthesis of concepts that are useful to cancer immunologists and pharmacologists, who tend to work in disparate fields with little cross-communication* Drs Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research* Summarizes the latest insights into how immune escape defines an essential trait of cancer* Includes numerous illustrations including: how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy; and how reversing immune suppression by the tumor can cause tumor regression
Nanotechnology Applications For Cancer Chemotherapy
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Author : Sanyog Jain
language : en
Publisher: Elsevier
Release Date : 2020-09-30
Nanotechnology Applications For Cancer Chemotherapy written by Sanyog Jain and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-30 with Technology & Engineering categories.
Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise summary of nanotechnological interventions for cancer management. It highlights the basics of oncology, the cancer microenvironment, targets for active drug delivery, the underlying mechanisms and molecular pathways to enhance the drug delivery to the cancer site. The book discusses the principles of basic and innovative nanocarrier-based therapeutic approaches to modulate the progression of the disease. In addition, this book also explores the evolving targeting approaches specific to the cancer site and type. The scope of the book is not limited to targeted drug delivery for various cancers, but also explores the advancements in cancer imaging and diagnostics employing the nanotechnological tools. Emphasis has been given on the important evaluation techniques like in-vitro cell culture and in-vivo animal models to assess the performance of cancer nanomedicines. The book includes clinical study reports of various drug moieties explored using variety of nanoconstructs in myriad cancer conditions with the input of global market and pharmacoeconomics. - Discusses how organic and inorganic nanoplatforms are being used in cancer treatment - Shows how nanotechnology is being used to create new and more accurate diagnostic tools - Surveys the current generation of cancer nanomedicines, assessing their advantages and challenges
Handbook Of Brain Tumor Chemotherapy Molecular Therapeutics And Immunotherapy
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Author : Herbert B. Newton
language : en
Publisher: Academic Press
Release Date : 2018-03-28
Handbook Of Brain Tumor Chemotherapy Molecular Therapeutics And Immunotherapy written by Herbert B. Newton and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-28 with Medical categories.
Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed. - Provides the most up-to-date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics for the treatment of brain tumors - Broadly appeals to anyone interested in neuro-oncology and the treatment of brain tumors - Features updated chapters on molecular biology, molecular therapeutics, maturation of immunotherapy approaches, and a focus on multidisciplinary molecular methods - Includes a new section on the basic science of immunology, as well as thorough updates on the use of vaccine technology and immunotherapy for the treatment of brain tumors
Natural Products Modulate The Sensitivity Of Cancer To Anti Pd 1 Based Immunotherapy
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Author : Qian Ba
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-10
Natural Products Modulate The Sensitivity Of Cancer To Anti Pd 1 Based Immunotherapy written by Qian Ba and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-10 with Science categories.
Combining Chemo Radio Therapy And Immunotherapy For Cancers Perfect Mix Of Old And New
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Author : Jian Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-10
Combining Chemo Radio Therapy And Immunotherapy For Cancers Perfect Mix Of Old And New written by Jian Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-10 with Medical categories.
Sphingolipids In Cancer
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Author :
language : en
Publisher: Academic Press
Release Date : 2018-07-27
Sphingolipids In Cancer written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-27 with Medical categories.
Sphingolipids in Cancer, Volume 140, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Topics discussed in this updated volume include Mechanisms of ceramide-dependent cancer cell death, Sphingolipids as regulators of autophagy and endocytic trafficking, The role and function of sphingomyelin biosynthesis in the development of cancer, Neutral sphingomyelinases in cancer: Friend or foe?, Sphingolipid rendezvous at the crossroad of NAFLD and senescence, Ceramide signaling and p53 pathways, Sphingolipid regulation of RNA Biology in cancer phenotypes, The role of ceramide-1-phosphate in tumor cell survival and dissemination, and more. - Provides information on cancer research, with this release focusing on sphingolipids - Offers outstanding and original reviews on a range of cancer research topics - Serves as an indispensable reference for researchers and students alike
Introduction For Liver 3d Bioprinting Book 1
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date : 2024-05-19
Introduction For Liver 3d Bioprinting Book 1 written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-19 with Medical categories.
The field of 3D bioprinting is rapidly evolving, offering unprecedented opportunities for medical and scientific advancements. "Introduction for Liver 3D Bioprinting – Book 1: Introduction to Cell Biology" is the first volume in a comprehensive series dedicated to exploring the intricate relationship between cellular biology and 3D bioprinting technology, specifically focusing on the liver. This book serves as a foundational text, aiming to bridge the gap between basic cell biology and its application in bioprinting. Understanding the principles of cell biology is crucial for anyone involved in tissue engineering, regenerative medicine, and 3D bioprinting, as it provides the essential knowledge needed to manipulate and cultivate cells effectively. In this volume, we delve into various aspects of cell biology, including the mechanisms of cellular processes, the roles of different cellular structures, and the intricacies of cellular signaling pathways. These topics are meticulously chosen to provide a broad yet detailed overview that sets the stage for more specialized discussions in subsequent volumes. Our goal is to equip researchers, students, and professionals with the knowledge required to innovate and excel in the field of 3D bioprinting. Each chapter is designed to build a strong conceptual framework, facilitating a deeper understanding of how cellular functions can be harnessed and manipulated for bioprinting applications. As you embark on this journey through the cellular world, we hope this book will inspire new ideas, foster scientific curiosity, and contribute to the growing body of knowledge in the field of bioprinting. Whether you are a seasoned researcher or new to the subject, this text aims to provide valuable insights and a solid foundation in cell biology, essential for advancing the science and application of 3D bioprinting. Thank you for joining us in exploring the fascinating intersection of cell biology and 3D bioprinting. We look forward to seeing the innovative solutions and breakthroughs that will emerge from your understanding and application of the concepts presented in this book.