Test No 422 Combined Repeated Dose Toxicity Study With The Reproduction Developmental Toxicity Screening Test


Test No 422 Combined Repeated Dose Toxicity Study With The Reproduction Developmental Toxicity Screening Test
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Test No 422 Combined Repeated Dose Toxicity Study With The Reproduction Developmental Toxicity Screening Test


Test No 422 Combined Repeated Dose Toxicity Study With The Reproduction Developmental Toxicity Screening Test
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 1996-03-22

Test No 422 Combined Repeated Dose Toxicity Study With The Reproduction Developmental Toxicity Screening Test written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-03-22 with categories.


The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks; females should be dosed throughout the study (approximately 54 days). Normally, matings “one male to one ...



Evaluation Of Oecd Screening Tests 421 Reproduction Developmental Toxicity Screening Test And 422 Combined Repeated Dose Toxicity Study With The Reproduction Developmental Toxicity Screening Test


Evaluation Of Oecd Screening Tests 421 Reproduction Developmental Toxicity Screening Test And 422 Combined Repeated Dose Toxicity Study With The Reproduction Developmental Toxicity Screening Test
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Author :
language : en
Publisher:
Release Date : 2002

Evaluation Of Oecd Screening Tests 421 Reproduction Developmental Toxicity Screening Test And 422 Combined Repeated Dose Toxicity Study With The Reproduction Developmental Toxicity Screening Test written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Toxicity testing categories.




Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 415 One Generation Reproduction Toxicity Study


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 415 One Generation Reproduction Toxicity Study
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2019-03-01

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 415 One Generation Reproduction Toxicity Study written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-01 with categories.


This Test Guideline for reproduction testing is designed to provide general information concerning the effects of a test substance (Solid, liquid, gas or vapour) on male and female reproductive performance. The test substance is administered orally ...



Short Term Methods For Estimating The Chronic Toxicity Of Effluents And Receiving Waters To Freshwater Organisms


Short Term Methods For Estimating The Chronic Toxicity Of Effluents And Receiving Waters To Freshwater Organisms
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Author :
language : en
Publisher:
Release Date : 1994

Short Term Methods For Estimating The Chronic Toxicity Of Effluents And Receiving Waters To Freshwater Organisms written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Effluent quality categories.




Toxicity Testing For Assessment Of Environmental Agents


Toxicity Testing For Assessment Of Environmental Agents
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-04-07

Toxicity Testing For Assessment Of Environmental Agents written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-07 with Nature categories.


Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants.



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 407 Repeated Dose 28 Day Oral Toxicity Study In Rodents


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 407 Repeated Dose 28 Day Oral Toxicity Study In Rodents
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2008-10-16

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 407 Repeated Dose 28 Day Oral Toxicity Study In Rodents written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-16 with categories.


This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 408 Repeated Dose 90 Day Oral Toxicity Study In Rodents


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 408 Repeated Dose 90 Day Oral Toxicity Study In Rodents
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2018-06-27

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 408 Repeated Dose 90 Day Oral Toxicity Study In Rodents written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-27 with categories.


This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose ...



Hayes Principles And Methods Of Toxicology


Hayes Principles And Methods Of Toxicology
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Author : A. Wallace Hayes
language : en
Publisher: CRC Press
Release Date : 2023-07-03

Hayes Principles And Methods Of Toxicology written by A. Wallace Hayes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-03 with Medical categories.


Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. "Principles of Toxicology"), major classes of established chemical hazards (Section II. "Agents"), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. "Methods"), as well as toxicology of specific target systems and organs (Section IV. "Organ- and System-Specific Toxicology"). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.



Methods For Measuring The Acute Toxicity Of Effluents And Receiving Waters To Freshwater And Marine Organisms


Methods For Measuring The Acute Toxicity Of Effluents And Receiving Waters To Freshwater And Marine Organisms
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Author :
language : en
Publisher: DIANE Publishing
Release Date : 2002

Methods For Measuring The Acute Toxicity Of Effluents And Receiving Waters To Freshwater And Marine Organisms written by and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Water quality biological assessment categories.




Toxicology For The Health And Pharmaceutical Sciences


Toxicology For The Health And Pharmaceutical Sciences
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Author : Antonio Peña-Fernández
language : en
Publisher: CRC Press
Release Date : 2021-12-21

Toxicology For The Health And Pharmaceutical Sciences written by Antonio Peña-Fernández and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-21 with Medical categories.


There is an increasing need for knowledge of toxicology to safeguard the use of chemicals in industry and in the public and private sectors. The study of toxicology is becoming increasingly relevant in human health sciences, as future health and clinical professionals will be pivotal in addressing and managing emerging chemical threats and hazards related to modern anthropogenic activities and technological development. Comprising a series of chapters from leading toxicology, pharmacy and public health academics and experts across Europe, the United States and beyond, Toxicology for the Health and Pharmaceutical Sciences provides a concise yet comprehensive volume that can be used as a relevant textbook on toxicology for the clinical, healthcare, educational and professional sectors. Key Features: Includes cutting edge information regarding the very lastest environmental threats to public health Provides a detailed case study based on a real-world scenario that allows the reader to practice human health risk assessment Describes innovative guidance and tools to respond to chemical incidents and attacks, which enables the reader to tailor an effective protection and remediation response This book covers the fundamentals and recent developments in toxicology, to respond to local and global chemical, pharmaceutical and environmental threats. Thus, this volume has chapters specifically designed to support the understanding of the most current toxicology-related subjects for any undergraduate/postgraduate health programs as well as aid the delivery of continuing professional development training on up-to-date topics in toxicology for current practicing health professionals wishing to improve their background knowledge in toxicology. The book is also vital reading and reference for policy makers and others that influence and set regulations that have an impact on the environment and human health.