The Mast Cell
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The Mast Cell In Health And Disease
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Author : Kaliner
language : en
Publisher: CRC Press
Release Date : 1992-10-29
The Mast Cell In Health And Disease written by Kaliner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-10-29 with Medical categories.
Offers coverage of practical and theoretical implications of current research into mast cell biology, emphasizing the role of the mast cell in human diseases. The text covers all aspects of the mast cell from growth and differentiation to its function in such conditions as asthma and skin disease.
Mast Cells
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Author : Guha Krishnaswamy
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
Mast Cells written by Guha Krishnaswamy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Medical categories.
A cutting-edge collection of readily reproducible techniques for the isolation, culture, and study of activation and signaling in human mast cells. These methods take advantage of the latest advances in molecular biology, technology, and information science. They include methods for the identification of mast cells, the development of mast cells in vitro, the study of mast cell signaling and gene expression, and the measurement of mast cell expression of inflammatory mediators. Additional chapters cover methods for studying mast cell interactions with other cell types (endothelial cells, fibroblasts, and B cells), the roles of mast cells in host defense, and mast cell apoptosis.
The Mast Cell
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Author : Domenico Ribatti
language : en
Publisher: Springer
Release Date : 2019-07-11
The Mast Cell written by Domenico Ribatti and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-11 with Medical categories.
Mast cells (MC) are phylogenetically old cells which are distributed throughout the human organism. MC are found in almost all of the major organs and tissues of the body, particularly in association with connective tissue structures such as blood vessels, lymphatic vessels and nerves, and in proximity to surfaces that interface the external environment, such as those of the respiratory and gastrointestinal system and the skin. This selective accumulation at tissue sites where foreign material attempts to invade the host suggests that MC are among the first cells to initiate defensive mechanisms. MC have long been recognized as key cells of type I hypersensitivity reactions. Several lines of evidence, however, indicate that they not only express critical effector functions in classic IgE-associated allergic disorders, but also play important roles in host defense against parasites, bacteria and perhaps even viruses. Indeed, it is now clear that MC can contribute to host defense in the context of either acquired or innate immune responses through the release of a myriad of pro-inflammatory and immunoregulatory molecules and the expression of a wide spectrum of surface receptors for cytokines and chemokines. Moreover, there is growing evidence that MC exert distinct non-immunological functions, playing a relevant role in tissue homeostasis, remodeling and fibrosis as well as in the processes of tissue angiogenesis.
The Mast Cells
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Author : Hans Selye
language : en
Publisher: Washington : Butterworths
Release Date : 1965
The Mast Cells written by Hans Selye and has been published by Washington : Butterworths this book supported file pdf, txt, epub, kindle and other format this book has been release on 1965 with Fiction categories.
Mast Cells Mediators And Disease
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Author : Stephen T. Holgate
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mast Cells Mediators And Disease written by Stephen T. Holgate and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In 1879 Paul Ehrlich first described the mast cell as a tissue fixed cell contain ing many granules which, when stained with basic dyes, such as toluidine blue, changed the colour spectrum of the dye in a process called meta chromasia. Since this early description, pathologists, physicians and pharmacologists have been fascinated by this cell on account of its central involvement in human allergic diseases. Approximately four decades after Ehrlich's first description of the mast cell, Prausnitz and Kiistner reported their pioneer experiment, demonstrating that the immediate skin wheal response to allergen could be passively transferred with serum. They named the antigen-specific serum factor reagin. A further four and one half decades had to pass before the connection between the mast cell and reagin could be made with the identification of reagin as an immunoglobulin E by Johansson and Ishizaka and its unique property to bind with high affinity to specific receptors on mast cells and basophils. Meanwhile in the 1920s Coca published a series of papers in which he described the clinical features of acute allergic responses and first used the term atopy. This, together with the fundamental pharmacological studies of Sir Henry Dale in identifying histamine as one mediator of the acute ana phylactic reaction, provided the second approach which eventually linked the mast cell to allergic tissue reactions. Indeed, it was Best, working in Dale's group who first showed that histamine was a chemical stored in mast cells.
The Mast Cell
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Author :
language : en
Publisher:
Release Date : 1979
The Mast Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Mast cells categories.
The Mast Cell Activation Syndrome Manual
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Author : June Corder
language : en
Publisher:
Release Date : 2021-08-10
The Mast Cell Activation Syndrome Manual written by June Corder and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-10 with categories.
Mast cells are allergy cells responsible for immediate allergic reactions. They cause allergic symptoms by releasing products called "mediators" stored inside them or made by them. In allergic reactions, this release occurs when the allergy antibody, which is present on the mast cell surfaces, binds to proteins that cause allergies, called allergens. This triggering is called activation, and the release of these mediators is called degranulation. Some of these mediators are stored in granules in the mast cells and are released quickly and others are made slowly only after the cell has been triggered. Mast cells can also be activated by other substances, such as medications, infections, insect or reptile venoms. These responses, while not desirable, are made by "normal" mast cells. They are called "secondary activation" because they are due to (secondary to) external stimuli. Sometimes mast cells become defective and release mediators because of abnormal internal signals. Certain mutations in mast cells can produce populations of identical mast cells - called clones - that overproduce and spontaneously release mediators. The spontaneous production of mediators in these clonal mast cell disorders is called "primary activation". These abnormal cells can grow uncontrollably and are unusually sensitive to activation in a condition called mastocytosis. This guide will show you the symptoms of MCAS as well as drugs to take, supplements, and natural treatment to end MCAS GET YOUR COPY TODAY BY SCROLLING UP AND CLICKING BUY NOW TO GET YOUR COPY TODAY
Mast Cell Biology
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Author : Alasdair M. Gilfillan
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-28
Mast Cell Biology written by Alasdair M. Gilfillan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Medical categories.
The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.
Mast Cells United A Holistic Approach To Mast Cell Activation Syndrome
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Author : Amber Walker
language : en
Publisher: Amber Walker
Release Date : 2019-03-16
Mast Cells United A Holistic Approach To Mast Cell Activation Syndrome written by Amber Walker and has been published by Amber Walker this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-16 with Medical categories.
At 542 pages and referencing over 1200 academic articles, this book is the longest and most thorough resource on mast cell activation syndrome (MCAS) to date. Allergies and anaphylaxis are on the rise, alongside gastrointestinal problems, skin issues, fatigue, orthopedic pain, neurological symptoms, and just about everything in between. Patients are coming out of the woodwork with chronic, debilitating, often invisible illness. Recent research estimates that 14%-17% of the population may have mast cell activation disease. Much of the medical community has never heard of the condition, and existing mainstream treatment tends to focus predominantly on pharmacological management. However, once a patient has reached a stable baseline, there are a number of other individualized approaches that can guide patients to successfully address the underlying root issues. This book includes: 1) an in-depth overview of mast cell activation disease, with a focus on mast cell activation syndrome (MCAS); 2) a patient story describing life with MCAS; 3) a detailed literature review and current hypotheses for disease origins; 4) a practical guide of clinical considerations for diagnosis; 5) a chapter devoted to comorbid conditions, including Ehlers-Danlos syndrome, POTS, Lyme disease and much more; 6) several chapters devoted to mainstream and natural treatment options, dietary considerations, and strategies for holistic healing; 7) content from dozens of interviews with prominent MCAS experts, including specialists in allergy/immunology, hematology, functional medicine, naturopathy, psychology, nutrition, gastroenterology, physical therapy, clinical research, and more! Whether a patient, medical practitioner, or family member/friend, this book empowers readers and provides patients with concrete steps to move forward in the diagnosis and comprehensive treatment of mast cell activation syndrome.
Human Mast Cells
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Author : Ann M. Dvorak
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Human Mast Cells written by Ann M. Dvorak and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This book looks in detail at human mast cells. It includes a review of previous and current ultrastructural studies, whereby the latter are illustrated with numerous high-quality electron micrographs obtained from a large number of structural and functional experiments using highly purified isolated human lung mast cells. Specifically, the book provides criteria for the identification of human mast cells, discusses the unique role in mast cell function of granules and lipid bodies, describes the ultrastructural anatomy of two release reactions - i.e., anaphylactic degranulation and piecemeal degranulation - and defines the recovery, cyclical and maturational properties of human mast cells. All of these new morphological-biochemical and functional studies are correlated with the author's wide experience in the visual properties of human mast cells as seen in biopsy material obtained from a diagnostic ultrastructural pathology service.
