The Alpha 1 Adrenergic Receptors

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The Alpha 1 Adrenergic Receptors

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Author : Jr. Ruffolo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Alpha 1 Adrenergic Receptors written by Jr. Ruffolo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

During the past decade, great strides have been made in our un derstanding of the biochemistry and pharmacology of the alpha-l adrenergic receptor. The alpha-l adrenergic receptor plays a key role in biological function. This is evidenced by the fact that the alpha-l adrenergic receptor plays a prominent functional role in most organs of the body and in the key systems responsible for survival of the organism and maintenance of optimum biological activity. This is most apparent in the cardiovascular system, in which alpha-l adrenergic receptors are the single most important receptor involved in the maintenance of blood pressure and circu latory function. It is appropriate, therefore, that recent findings related to the pharmacology and biochemistry of the alpha-l adrenergic receptor be compiled, since this subject has not been reviewed in detail in recent years. It is the purpose of this book to present a series of reviews of key experimental findings that shed new light on the alpha-l adrenergic receptor and the manner in which it functions. Classically, most receptors have been characterized based on structure-activity relationships obtained for selective agonists and antagonists interacting with the receptor. Although there are many newer and more sophisticated approaches to receptor char acterization, structure-activity relationships still provide impor tant information regarding the chemical requirements made by the receptor for its occupation by ligands and its subsequent acti vation by those ligands possessing intrinsic efficacy and, there fore, agonist activity.

Hepatotoxicity

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Author : Hyman J. Zimmerman
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1999

Hepatotoxicity written by Hyman J. Zimmerman and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Alpha2adrenergic Receptors

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Author : Lewis L. Lanier
language : en
Publisher: CRC Press
Release Date : 1997-02-06

Alpha2adrenergic Receptors written by Lewis L. Lanier and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-02-06 with Science categories.

This book undertakes to cover all angles of current research in (actual symbol not reproducible) receptors, each chapter being written by a leader in the field. Starting with an excellent overview of the subject, it provides insights into ligand binding and the effects of site-directed mutagenesis; the transfer of the signal through the G-protein to various effectors and the internal cellular response; receptor trafficking; and the therapeutic implications of the receptors, with the effects of agonists and antagonists. The scope of this volume makes it an indispensable guide for researchers working on any feature of (actual symbol not reproducible) receptors. It will also prove valuable to anyone with an interest in the structure and function of G-protein coupled receptors and the mechanisms by which they direct the response of the cell to multiple types of external stimuli.

Adrenergic Alpha Receptors Advances In Research And Application 2012 Edition

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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26

Adrenergic Alpha Receptors Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.

Adrenergic alpha Receptors—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Adrenergic alpha Receptors in a compact format. The editors have built Adrenergic alpha Receptors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Adrenergic alpha Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Adrenergic alpha Receptors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Alpha 2 Adrenergic Receptors

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Author : Lee E. Limbird
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Alpha 2 Adrenergic Receptors written by Lee E. Limbird and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Drug Induced Liver Disease

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Author : Neil Kaplowitz
language : en
Publisher: CRC Press
Release Date : 2002-10-16

Drug Induced Liver Disease written by Neil Kaplowitz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-10-16 with Medical categories.

Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.

Introduction To Basics Of Pharmacology And Toxicology

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Author : Abialbon Paul
language : en
Publisher: Springer Nature
Release Date : 2021-03-13

Introduction To Basics Of Pharmacology And Toxicology written by Abialbon Paul and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-13 with Medical categories.

This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Endothelium And Cardiovascular Diseases

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Author : Protasio Lemos Da Luz
language : en
Publisher: Academic Press
Release Date : 2018-02-03

Endothelium And Cardiovascular Diseases written by Protasio Lemos Da Luz and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-03 with Medical categories.

Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

Movement Disorders

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Author : Mark S. LeDoux
language : en
Publisher: Elsevier
Release Date : 2014-10-24

Movement Disorders written by Mark S. LeDoux and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-24 with Medical categories.

The use of animal models is a key aspect of scientific research in numerous fields of medicine. Movement Disorders, Second Edition vigorously examines the important contributions and application of animal models to the understanding of human movement disorders, and serves as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration, and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. Introduces the scientific foundations for modern movement disorders research Contributing authors are internationally known experts Completely revised with 20% new material Provides a comprehensive discussion of genetics for each type of movement disorder Covers Parkinson's disease, Huntington's disease, dystonia, tremors, and tics

Veterinary Anesthesia And Analgesia

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Author : Kurt A. Grimm
language : en
Publisher: John Wiley & Sons
Release Date : 2015-05-11

Veterinary Anesthesia And Analgesia written by Kurt A. Grimm and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-11 with Medical categories.

Veterinary Anesthesia and Analgesia: the Fifth Edition of Lumb and Jones is a reorganized and updated edition of the gold-standard reference for anesthesia and pain management in veterinary patients. Provides a thoroughly updated edition of this comprehensive reference on veterinary anesthesia and analgesia, combining state-of-the-art scientific knowledge and clinically relevant information Covers immobilization, sedation, anesthesia, and analgesia of companion, wild, zoo, and laboratory animals Takes a body systems approach for easier reference to information about anesthetizing patients with existing conditions Adds 10 completely new chapters with in-depth discussions of perioperative heat balance, coagulation disorders, pacemaker implantation, cardiac output measurement, cardiopulmonary bypass, shelter anesthesia and pain management, anesthetic risk assessment, principles of anesthetic pharmacology, and more Now printed in color, with more than 400 images