The Annotated Hodgkin And Huxley
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The Annotated Hodgkin And Huxley
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Author : Indira M. Raman
language : en
Publisher: Princeton University Press
Release Date : 2022-01-11
The Annotated Hodgkin And Huxley written by Indira M. Raman and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-11 with Science categories.
The first annotated edition of the scientific papers that created the foundation of modern neuroscience and physiology The origin of everything known about how neurons and muscles generate electrical signals can be traced back to five revolutionary papers, published in the Journal of Physiology in 1952 by Alan Hodgkin and Andrew Huxley. The principles they revealed remain cornerstones of the discipline, summarized in every introductory neuroscience and physiology course. Since that era, however, scientific practice, technology, and presentation have changed extensively. It is difficult for the modern reader to appreciate Hodgkin and Huxley’s rigorous scientific thought, elegant experimental design, ingenious analysis, and beautiful writing. This book provides the first annotated edition of these papers, offering essential background on everything, from terminology, equations, and electronics, to the greater historical and scientific context surrounding the work. The original journal pages are displayed opposite detailed notes explaining content, process, and background, with copies of the figures replotted according to modern conventions. Indispensable for scientists, teachers, and trainees alike, The Annotated Hodgkin and Huxley makes an essential body of knowledge—and an unparalleled approach to research—accessible to a new generation of readers. Reproduces the original articles paired with extensive annotations on facing pages Replots figures with modern conventions of data display Explains the development of the voltage clamp and the discovery of ionic currents and action potential generation, foundational to the study of neuroscience and physiology Summarizes the history of electrophysiology leading to Hodgkin and Huxley’s work Includes appendices on relevant concepts from mathematics, physics, electronics, chemical kinetics, and numerical methods
The Annotated Hodgkin And Huxley
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Author : Indira M. Raman
language : en
Publisher: Princeton University Press
Release Date : 2022-01-11
The Annotated Hodgkin And Huxley written by Indira M. Raman and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-11 with Medical categories.
Historical background -- Paper 1 -- Paper 2 -- Paper 3 -- Paper 4 -- Paper 5.
Metrics At Work
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Author : Angèle Christin
language : en
Publisher: Princeton University Press
Release Date : 2020-06-30
Metrics At Work written by Angèle Christin and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-30 with Social Science categories.
The starkly different ways that American and French online news companies respond to audience analytics and what this means for the future of news When the news moved online, journalists suddenly learned what their audiences actually liked, through algorithmic technologies that scrutinize web traffic and activity. Has this advent of audience metrics changed journalists’ work practices and professional identities? In Metrics at Work, Angèle Christin documents the ways that journalists grapple with audience data in the form of clicks, and analyzes how new forms of clickbait journalism travel across national borders. Drawing on four years of fieldwork in web newsrooms in the United States and France, including more than one hundred interviews with journalists, Christin reveals many similarities among the media groups examined—their editorial goals, technological tools, and even office furniture. Yet she uncovers crucial and paradoxical differences in how American and French journalists understand audience analytics and how these affect the news produced in each country. American journalists routinely disregard traffic numbers and primarily rely on the opinion of their peers to define journalistic quality. Meanwhile, French journalists fixate on internet traffic and view these numbers as a sign of their resonance in the public sphere. Christin offers cultural and historical explanations for these disparities, arguing that distinct journalistic traditions structure how journalists make sense of digital measurements in the two countries. Contrary to the popular belief that analytics and algorithms are globally homogenizing forces, Metrics at Work shows that computational technologies can have surprisingly divergent ramifications for work and organizations worldwide.
Foundations Of Cellular Neurophysiology
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Author : Daniel Johnston
language : en
Publisher: MIT Press
Release Date : 1994-11-02
Foundations Of Cellular Neurophysiology written by Daniel Johnston and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-11-02 with Medical categories.
with simulations and illustrations by Richard Gray Problem solving is an indispensable part of learning a quantitative science such as neurophysiology. This text for graduate and advanced undergraduate students in neuroscience, physiology, biophysics, and computational neuroscience provides comprehensive, mathematically sophisticated descriptions of modern principles of cellular neurophysiology. It is the only neurophysiology text that gives detailed derivations of equations, worked examples, and homework problem sets (with complete answers). Developed from notes for the course that the authors have taught since 1983, Foundations of Cellular Neurophysiology covers cellular neurophysiology (also some material at the molecular and systems levels) from its physical and mathematical foundations in a way that is far more rigorous than other commonly used texts in this area.
Galileo Unbound
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Author : David D. Nolte
language : en
Publisher: Oxford University Press
Release Date : 2018-07-12
Galileo Unbound written by David D. Nolte and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-12 with Science categories.
Galileo Unbound traces the journey that brought us from Galileo's law of free fall to today's geneticists measuring evolutionary drift, entangled quantum particles moving among many worlds, and our lives as trajectories traversing a health space with thousands of dimensions. Remarkably, common themes persist that predict the evolution of species as readily as the orbits of planets or the collapse of stars into black holes. This book tells the history of spaces of expanding dimension and increasing abstraction and how they continue today to give new insight into the physics of complex systems. Galileo published the first modern law of motion, the Law of Fall, that was ideal and simple, laying the foundation upon which Newton built the first theory of dynamics. Early in the twentieth century, geometry became the cause of motion rather than the result when Einstein envisioned the fabric of space-time warped by mass and energy, forcing light rays to bend past the Sun. Possibly more radical was Feynman's dilemma of quantum particles taking all paths at once -- setting the stage for the modern fields of quantum field theory and quantum computing. Yet as concepts of motion have evolved, one thing has remained constant, the need to track ever more complex changes and to capture their essence, to find patterns in the chaos as we try to predict and control our world.
Encyclopedia Of Computational Neuroscience
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Author : Dieter Jaeger
language : en
Publisher:
Release Date :
Encyclopedia Of Computational Neuroscience written by Dieter Jaeger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Computational neuroscience categories.
Fundamentals Of Computational Neuroscience
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Author : Thomas Trappenberg
language : en
Publisher: Oxford University Press (UK)
Release Date : 2010
Fundamentals Of Computational Neuroscience written by Thomas Trappenberg and has been published by Oxford University Press (UK) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Mathematics categories.
The new edition of Fundamentals of Computational Neuroscience build on the success and strengths of the first edition. It introduces the theoretical foundations of neuroscience with a focus on the nature of information processing in the brain. The book covers the introduction and motivation of simplified models of neurons that are suitable for exploring information processing in large brain-like networks. Additionally, it introduces several fundamental networkarchitectures and discusses their relevance for information processing in the brain, giving some examples of models of higher-order cognitive functions to demonstrate the advanced insight that can begained with such studies.
The Neuron Book
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Author : Nicholas T. Carnevale
language : en
Publisher: Cambridge University Press
Release Date : 2006-01-12
The Neuron Book written by Nicholas T. Carnevale and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-12 with Medical categories.
The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.
A History Of The Brain
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Author : Andrew P. Wickens
language : en
Publisher: Psychology Press
Release Date : 2014-12-08
A History Of The Brain written by Andrew P. Wickens and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-08 with Psychology categories.
A History of the Brain tells the full story of neuroscience, from antiquity to the present day. It describes how we have come to understand the biological nature of the brain, beginning in prehistoric times, and progressing to the twentieth century with the development of Modern Neuroscience. This is the first time a history of the brain has been written in a narrative way, emphasizing how our understanding of the brain and nervous system has developed over time, with the development of the disciplines of anatomy, pharmacology, physiology, psychology and neurosurgery. The book covers: beliefs about the brain in ancient Egypt, Greece and Rome the Medieval period, Renaissance and Enlightenment the nineteenth century the most important advances in the twentieth century and future directions in neuroscience. The discoveries leading to the development of modern neuroscience gave rise to one of the most exciting and fascinating stories in the whole of science. Written for readers with no prior knowledge of the brain or history, the book will delight students, and will also be of great interest to researchers and lecturers with an interest in understanding how we have arrived at our present knowledge of the brain.
Advanced Chemical Biology
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Author : Howard C. Hang
language : en
Publisher: John Wiley & Sons
Release Date : 2023-02-21
Advanced Chemical Biology written by Howard C. Hang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-21 with Science categories.
Advanced Chemical Biology The modern approach to teaching chemical biology Advanced Chemical Biology is organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections. Every chapter is homogeneous in style and layout, consisting of a short historical introduction followed by a description of the underlying concepts and a selection of recent examples of how the concept has been turned into practice. The subdivision of the contents into core and supplemental chapters enables a flexible use in teaching, both for a one-semester and a two-semester course. Written by authors and editors coming from the leading scientific institutions that have developed the concepts and technologies for this discipline, Advanced Chemical Biology includes specific information on topics like: DNA function, synthesis and engineering, chemical approaches to genome integrity, and RNA function, synthesis, and probing Chemical approaches to transcription and RNA regulation in vivo, chemical biology of genome engineering, and peptide/protein synthesis and engineering Directed evolution for chemical biology, chemical biology of cellular metabolism, chemical biology of lipids, and protein post-translational modifications Chemical glycobiology, chemical and enzymatic modification of proteins, genetic code expansion, bio-orthogonal chemistry, and cellular imaging With its broad scope and focus on turning concepts into applications, Advanced Chemical Biology is an excellent starting point for anyone entering the field and looking for a guide to the wide range of available methods and strategies that chemical biology has to offer. With a Foreword by Nobel Laureate Carolyn Bertozzi.