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The Application Of Bioactive Materials In Bone Repair


The Application Of Bioactive Materials In Bone Repair
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The Application Of Bioactive Materials In Bone Repair


The Application Of Bioactive Materials In Bone Repair
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Author : Hu Yan
language : en
Publisher: Frontiers Media SA
Release Date : 2025-03-04

The Application Of Bioactive Materials In Bone Repair written by Hu Yan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-04 with Science categories.


Biological activity, in the field of materials, mainly refers to the properties that can induce special biological and chemical reactions at the interface between materials and biological tissues, forming chemical bonds between materials and biological tissues. A bioactive material is a biomaterial that is able to participate in a regenerative process at the molecular level and dictate molecular and cellular events in a preferred and predictable way. In the process of biomineralization, the ability of biological material to chemically bond with living bone is an important index of the biomaterial, and the biological activity of the material in vivo is reflected by the simulated body fluid-SBF ability of apatite formed on the surface of the material. In the field of bone repair, bioactive materials such as hydrogels, agglomerates, and magnetic nanoparticles are playing an increasingly important role. Compared with traditional bone repair materials, bioactive materials have many advantages, such as high biocompatibility, simulation of the extracellular environment, and easy engineering modification. In addition, as a delivery system, bioactive materials are modified and engineered to be minimally invasive, targeted, and sustainably released. The above characteristics have important application value in the field of bone repair. This Research Topic aims to promote the use of bioactive materials in bone repair and recruit bioactive materials at the forefront of bone repair research. Here we discuss the properties and characterization of different kinds of bioactive materials. These materials mainly include 1) bioactive materials for the molecular mechanism of bone repair; 2) bioactive materials for targeted drug delivery systems; 3) bioactive materials for injection or microneedles. The establishment of this Research Topic hopes to further promote the interdisciplinary interaction between medicine and industry, as well as to promote the clinical transformation and application of new biological materials. In this Research Topic, we welcome researchers to submit perspectives, original articles, reviews, comments, case reports, and letters on the topic, including but not limited to the following topics: • new ways of preparing materials related to bone repair • advanced research on characterization, detection, and engineering modification of bioactive materials for bone repair • research on bioactive materials for bone repair through molecular mechanisms • research on bioactive materials for different interventions in bone repair • to summarize the current status of the application of bioactive materials in bone repair



Bone Repair Biomaterials


Bone Repair Biomaterials
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Author : Kendell Pawelec
language : en
Publisher: Woodhead Publishing
Release Date : 2018-11-29

Bone Repair Biomaterials written by Kendell Pawelec and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-29 with Technology & Engineering categories.


Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. - Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area - Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing - Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges - Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites



Bioactive Materials For Bone Regeneration


Bioactive Materials For Bone Regeneration
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Author : Jiang Chang
language : en
Publisher: Academic Press
Release Date : 2020-02-28

Bioactive Materials For Bone Regeneration written by Jiang Chang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-28 with Technology & Engineering categories.


Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration. - Provides readers with the latest research developments in the fabrication techniques of bioactive materials for tissue regeneration and tissue engineering applications - Presents the latest research advancements on how bioactive materials interact with the host and induce micro-environments for stem cell differentiation, immunomodulation and tissue regeneration - Covers the methods, strategies, principle and mechanisms on constructing beneficial biomaterial microenvironments



Learning From Nature How To Design New Implantable Biomaterials From Biomineralization Fundamentals To Biomimetic Materials And Processing Routes


Learning From Nature How To Design New Implantable Biomaterials From Biomineralization Fundamentals To Biomimetic Materials And Processing Routes
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Author : Rui L. Reis
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-12-29

Learning From Nature How To Design New Implantable Biomaterials From Biomineralization Fundamentals To Biomimetic Materials And Processing Routes written by Rui L. Reis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-29 with Technology & Engineering categories.


The development of materials for any replacement or regeneration application should be based on the thorough understanding of the structure to be substituted. This is true in many fields, but particularly exigent in substitution and regeneration medicine. The demands upon the material properties largely depend on the site of application and the function it has to restore. Ideally, a replacement material should mimic the living tissue from a mechanical, chemical, biological and functional point of view. Of course this is much easier to write down than to implement in clinical practice. Mineralized tissues such as bones, tooth and shells have attracted, in the last few years, considerable interest as natural anisotropic composite structures with adequate mechanical properties. In fact, Nature is and will continue to be the best materials scientist ever. Who better than nature can design complex structures and control the intricate phenomena (processing routes) that lead to the final shape and structure (from the macro to the nano level) of living creatures? Who can combine biological and physico-chemical mechanisms in such a way that can build ideal structure-properties relationships? Who, else than Nature, can really design smart structural components that respond in-situ to exterior stimulus, being able of adapting constantly their microstructure and correspondent properties? In the described philosophy line, mineralized tissues and biomineralization processes are ideal examples to learn-from for the materials scientist of the future.



Laser Surface Modification Of Biomaterials


Laser Surface Modification Of Biomaterials
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Author : Rui Vilar
language : en
Publisher: Woodhead Publishing
Release Date : 2016-04-15

Laser Surface Modification Of Biomaterials written by Rui Vilar and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-15 with Technology & Engineering categories.


Laser Surface Modification of Biomaterials: Techniques and Applications covers this expanding field, which has many potential applications, including biomaterials. Laser surface modification of biomaterials enables the production of hybrid materials with different functionality in the bulk as well as the thin, sub-micrometer surface layer. This book will provide readers with a comprehensive review of the technology and its applications. Chapters in Part 1 look at the techniques and considerations of laser surface modification, while Part 2 reviews laser surface modification techniques of the most important classes of biomaterials, with a final set of chapters discussing application specific laser surface modification. - Offers a comprehensive review of laser surface modification techniques - Presents recent developments, fundamentals, and progress in laser surface modification - Reviews laser surface modification applications across a range of materials - Emphasizes applications in biomaterials



Wound Healing Biomaterials Volume 1


Wound Healing Biomaterials Volume 1
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Author : Magnus Ågren
language : en
Publisher: Woodhead Publishing
Release Date : 2016-06-03

Wound Healing Biomaterials Volume 1 written by Magnus Ågren and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-03 with Medical categories.


Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials. - Provides more systematic and comprehensive coverage of specific therapies and biomaterials for wound healing - Highlights research that is concerned with new therapies, regeneration methods, and the use of biomaterials to assist in wound healing and healing response - Presents an organized layout of the material that is carefully arranged with clear titles and comprehensive section headings - Looks at tissue regeneration strategies, making this an all encompassing book on the topic of wound care



Wound Healing Biomaterials Volume 2


Wound Healing Biomaterials Volume 2
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Author : Magnus Ågren
language : en
Publisher: Woodhead Publishing
Release Date : 2016-05-30

Wound Healing Biomaterials Volume 2 written by Magnus Ågren and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-30 with Technology & Engineering categories.


Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care. - Includes more systematic and comprehensive coverage on the topic of wound care - Provides thorough coverage of all specific therapies and biomaterials for wound healing - Contains clear layout and organization that is carefully arranged with clear titles and comprehensive section headings - Details specific sections on the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and more



Biomineralization And Biomaterials


Biomineralization And Biomaterials
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Author : Conrado Aparicio
language : en
Publisher: Woodhead Publishing
Release Date : 2015-09-28

Biomineralization And Biomaterials written by Conrado Aparicio and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-28 with Science categories.


Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years. Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance. - Provides a thorough overview of the biomineralization process - Presents the most recent information on the natural process by which crystals in tissues form into inorganic structures such as bone, teeth, and other natural mineralized tissues - Investigates methods for improving mineralization - Explores new techniques that will help improve the biomimetic process



Bioactive Materials In Medicine


Bioactive Materials In Medicine
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Author : X. Zhao
language : en
Publisher: Elsevier
Release Date : 2011-05-25

Bioactive Materials In Medicine written by X. Zhao and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-25 with Technology & Engineering categories.


Bioactive materials play an increasingly important role in the biomaterials industry, and are used for a range of applications, including artificial organs, drug delivery systems, nanomedicine, and biosensors. Bioactive materials in medicine reviews the current status and ongoing development of bioactive materials for medical applications.Following an introduction to bioactive materials in medicine, part one covers the process of designing bioactive materials, including chapters on molecular design, nanotechnology, and tissue engineering. Part two focuses on the different applications of bioactive materials in medicine, with chapters discussing applications in orthopaedics, in the circulatory system,and as antibacterials. The final chapters focus on the uses of these materials in gene therapy, plastic surgery and body reconstruction, and in drug delivery systems.With its distinguished editors and international team of contributors, Bioactive materials in medicine is an essential reference for researchers and designers in industry, as well as those with an academic interest in the subject. - Discusses the current status and ongoing development of bioactive materials for medical applications - Explores the process of designing bioactive materials, including molecular design, nanotechnology, and tissue engineering - Assesses different applications of bioactive materials in medicine featuring applications in orthopaedics, in the circulatory system,and as antibacterials



Encyclopedia Of Bone Biology


Encyclopedia Of Bone Biology
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-06-26

Encyclopedia Of Bone Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-26 with Science categories.


Encyclopedia of Bone Biology, Three Volume Set covers hot topics from within the rapidly expanding field of bone biology and skeletal research, enabling a complete understanding of both bone physiology and its relation to other organs and pathophysiology. This encyclopedia will serve as a vital resource for those involved in bone research, research in other fields that cross link with bone, such as metabolism and immunology, and physicians who treat bone diseases. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from advanced undergraduate students to research professionals. Chapters also explore the latest advances and hot topics that have emerged in recent years, including the Hematopoietic Niche and Nuclear Receptors. In the electronic edition, each chapter will include hyperlinked references and further readings as well as cross-references to related articles. Incorporates perspectives from experts working within the domains of biomedicine, including physiology, pathobiology, pharmacology, immunology, endocrinology, orthopedics and metabolism Provides an authoritative introduction for non-specialists and readers from undergraduate level upwards, as well as up-to-date foundational content for those familiar with the field Includes multimedia features, cross-references and color images/videos