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The Art And Science Of Dermal Formulation Development


The Art And Science Of Dermal Formulation Development
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The Art And Science Of Dermal Formulation Development


The Art And Science Of Dermal Formulation Development
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Author : Marc B. Brown
language : en
Publisher: CRC Press
Release Date : 2019-03-01

The Art And Science Of Dermal Formulation Development written by Marc B. Brown and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-01 with Medical categories.


The Art and Science of Dermal Formulation Development is a comprehensive guide to the theory and practice of transdermal and topical formulation development, covering preclinical studies, evaluation, and regulatory approval. It enables the reader to understand the opportunities and challenges in developing products and how risks can be mitigated. Over the last 25 years, expertise in this area has declined whilst drug delivery systems for other administration routes have developed significantly. The advantages offered by transdermal and topical drug delivery remain compelling for sectors including the pharmaceutical industry, personal care, and cosmetics. This text addresses the dearth of expertise and discusses how skin can be a route of delivery and the processes in formulation development, but how such an application is very different to that used for oral, IV, and other administration routes. Key Features: Presents a practical guide for both industry and academia Focuses on and draws together the fundamental principles behind transdermal and topical drug delivery Illustrates the practicalities of formulation design using key case studies Gives an understanding of the skin as a route of delivery and how formulation development for such application differs from that for other administration routes



The Art And Science Of Dermal Formulation Development


The Art And Science Of Dermal Formulation Development
DOWNLOAD
Author : Marc B. Brown
language : en
Publisher: CRC Press
Release Date : 2019

The Art And Science Of Dermal Formulation Development written by Marc B. Brown and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Medical categories.


The Art and Science of Dermal Formulation Development is a comprehensive guide to the theory and practice of transdermal and topical formulation development, covering preclinical studies, evaluation, and regulatory approval. It enables the reader to understand the opportunities and challenges in developing products and how risks can be mitigated. Over the last 25 years, expertise in this area has declined whilst drug delivery systems for other administration routes have developed significantly. The advantages offered by transdermal and topical drug delivery remain compelling for sectors including the pharmaceutical industry, personal care, and cosmetics. This text addresses the dearth of expertise and discusses how skin can be a route of delivery and the processes in formulation development, but how such an application is very different to that used for oral, IV, and other administration routes. Key Features: Presents a practical guide for both industry and academia Focuses on and draws together the fundamental principles behind transdermal and topical drug delivery Illustrates the practicalities of formulation design using key case studies Gives an understanding of the skin as a route of delivery and how formulation development for such application differs from that for other administration routes



The Art And Science Of Dermal Formulation Development


The Art And Science Of Dermal Formulation Development
DOWNLOAD
Author : Marc B. Brown
language : en
Publisher: CRC Press
Release Date : 2019-03-01

The Art And Science Of Dermal Formulation Development written by Marc B. Brown and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-01 with Medical categories.


The Art and Science of Dermal Formulation Development is a comprehensive guide to the theory and practice of transdermal and topical formulation development, covering preclinical studies, evaluation, and regulatory approval. It enables the reader to understand the opportunities and challenges in developing products and how risks can be mitigated. Over the last 25 years, expertise in this area has declined whilst drug delivery systems for other administration routes have developed significantly. The advantages offered by transdermal and topical drug delivery remain compelling for sectors including the pharmaceutical industry, personal care, and cosmetics. This text addresses the dearth of expertise and discusses how skin can be a route of delivery and the processes in formulation development, but how such an application is very different to that used for oral, IV, and other administration routes. Key Features: Presents a practical guide for both industry and academia Focuses on and draws together the fundamental principles behind transdermal and topical drug delivery Illustrates the practicalities of formulation design using key case studies Gives an understanding of the skin as a route of delivery and how formulation development for such application differs from that for other administration routes



Art And Science Of Formulating Cosmetic Products


Art And Science Of Formulating Cosmetic Products
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Author : Germain Puccetti
language : en
Publisher:
Release Date : 2016-01-03

Art And Science Of Formulating Cosmetic Products written by Germain Puccetti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-03 with Medical categories.


The new 9th edition of Harry's Cosmeticology is available as a 3 volume set containing over 2600 pages of new information on the recent changes in the cosmetic and personal care industry. Chemical Publishing is now offering key parts of the title for those interested in a particular subject area covered in the book. Harry's Cosmeticology 9th Edition has developed a new line of "Focus Books" for this purpose. Focus books are a series of selected chapters that can be used as a reference guide for a particular subject area. This focus book covers: - Part 6 Formulating - Formulating Cosmetics and Personal Care Products - Editor: - Charles Warren - Contributors: Eva Patel, Skin Rx- Gurpreet (Gogi) Sangha, CEO of G.S. Cosmeceutical - Mark Lees, Ph.D., M.S., CIDESCO Diplomate - Germain Puccetti, Ashland Chemical - Nevine Issa, and Hani Fares Ph.D. - Carrie Shipley, Grain Processing Corporation - Padmaja Prem, VP of Combe's Global Research - Skin Care - 6.1 Formulating Wisdom Category by Category (Author: Charles Warren)- 6.2 Skin Lightening, Whitening, and Brightening: An Overview of Approaches, Key Ingredients, and Formulations for Enhancing Skin Appearance and Correcting/Minimizing Common Skin Pigmentation Disorders (Authors: Eva Patel and Gogi Sangha) - 6.3 Sunscreens - 6.4 Antiperspirants / Deodorants - 6.5 Acne, Oily, ad Aging Skin Product Formulation (Author Mark Lees) - a. The Acne-Prone and Clog-Prone Skin: A Client Profile - 6.5.2. Review of factors in acne development - 6.5.3 Management of acne-prone skin - 6.5.4 A Program Approach - 6.6 Face and Body - Masks / Scrubs (Author Charles Warren) - 6.6.1 Cleansers/Scrubs - 6.6.2 Wipes - 6.6.3 Moisturizers - 6.6.4 Treatments - 6.6.5 Perfumes/Fragrances - 6.7 Shaving Preparations: Pre and Post (Author Charles Warren) - 6.7.1 Men's Products - Pigmented Cosmetics - 6.8 Color Cosmetics: An Introduction to Formulation and Approaches for Mascaras, Foundations and Lipsticks (Authors: Germain Puccetti, Nevine Issa, Hani Fares) - 6.8.1 Color cosmetics and the consumer perspective - 6.8.2 Foundations - a. Formulas - b. Pigments - 6.8.3 Lipsticks and lip-glosses - 6.8.4 Mascaras - 6.8.5 Skincare actives in foundations and lipsticks - Hair Care - 6.10 Shampoos - Ingredients, Formulation and Efficacy Evaluation (Author Carrie Shipley, Applications Scientist, Grain Processing Corporation) - Section I: Typical Shampoo Ingredients - Section II: Hair-Cleansing Mechanism - Section III: Shampoo Evaluation - Section IV: Future Trends in Shampoos - 6.11 Hair Styling (Author Charles Warren) - 6.12 Specialty Styling Products - 6.13 Permanent Waving - 6.14 Conditioners/Treatments - 6.15 Hair Colorants and Protection - Author: Padmaja Prem, Combe Incorporated - 6.16 Reactive Hair Care Products (Author Charles Warren) - 6.17 Formula/Product Development from the Formulator's Viewpoint (Expectations, Initial Prototypes, Final Prototypes) (Author Charles Warren) - Part 6.18 - Oral Care: Formulating Products and Practices for Health and Beauty - Editor: - Caren M. Barnes Professor Coordinator of Clinical Research University of Nebraska Medical Center College of Dentistry - Contributors: - Chi Shing Wong Member, Product Development Group Colgate-Palmolive Global Toothbrush Division - James G Masters, Ph.D. Director in the Research and Development Division Colgate-Palmolive Company - Shira Pilch, Ph.D. Associate Director: Research and Development Division Colgate-Palmolive Company - Michael Prencipe, Ph.D. Director in the Research and Development Division Colgate-Palmolive Company - Table of Contents: - A. Important Issues in Oral Health - B. Importance of Aesthetics in Dentistry - C. Halitosis (oral malodor) - D. Oral Issues Related to Aging - 6.18.1 Personal Oral Care - 6.18.2 Oral Hygiene Aids -



Cosmetic Formulation


Cosmetic Formulation
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Author : Heather A.E. Benson
language : en
Publisher: CRC Press
Release Date : 2019-04-05

Cosmetic Formulation written by Heather A.E. Benson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-05 with Medical categories.


Cosmetics are the most widely applied products to the skin and include creams, lotions, gels and sprays. Their formulation, design and manufacturing ranges from large cosmetic houses to small private companies. This book covers the current science in the formulations of cosmetics applied to the skin. It includes basic formulation, skin science, advanced formulation, and cosmetic product development, including both descriptive and mechanistic content with an emphasis on practical aspects. Key Features: Covers cosmetic products/formulation from theory to practice Includes case studies to illustrate real-life formulation development and problem solving Offers a practical, user-friendly approach, relying on the work of recognized experts in the field Provides insights into the future directions in cosmetic product development Presents basic formulation, skin science, advanced formulation and cosmetic product development



Dermatological Drug Development


Dermatological Drug Development
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Author : Tomoko Maeda-Chubachi
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2020-09-18

Dermatological Drug Development written by Tomoko Maeda-Chubachi and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-18 with Medical categories.


This book uniquely summarizes approaches to developing dermatological drugs in a regulated environment from the perspective of the pharmaceutical industry. It brings together the insights of skilled and experienced industry experts to reveal the complexities of dermatological drug development, covering topical, oral, and biologic drugs. This book fills an important gap, as there is currently no other textbook addressing dermatological drug development, explaining and illustrating why unique nonclinical and clinical studies are necessary and how they are typically designed and conducted. The drug development process is also an evolving strategy that is characterized by communicating, negotiating, and agreeing with regulatory agencies, such as FDA (US), EMA (EU), and PMDA (Japan).



Dermal Drug Delivery


Dermal Drug Delivery
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Author : Tapash K. Ghosh
language : en
Publisher: CRC Press
Release Date : 2020-01-21

Dermal Drug Delivery written by Tapash K. Ghosh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-21 with Medical categories.


With the continued advancement of better-quality control and patient outcome reporting systems, changes in the development, control, and regulation of all pharmaceutical delivery systems including transdermal and topical products have been happening on a continuous basis. In light of various quality issues that have been reported by patients and practitioners resulting in the recall or removal of products from the market, both the pharmaceutical industries and regulatory agencies have been adopting new measures to address these issues. With chapters written by experts in this field, this book takes a 21st century multidisciplinary and cross-functional look at these dosage forms to improve the development, design, manufacturing, quality, clinical performance, safety, and regulation of these products. This book offers a wealth of up-to-date information organized in a logical sequence corresponding to various stages of research, development, and commercialization of dermal drug delivery products. The authors have been carefully selected from different sectors of pharmaceutical science for their expertise in their selected areas to present objectively a balanced view of the current state of these products development and commercialization via regulatory approval. Their insights will provide useful information to others to ensure the successful development of the next generation dermal drug products. Key Features: Presents current advancements including new technologies of transdermal and topical dosage forms. Presents challenges in the development of the new generation of transdermal and topical dosage forms. Introduces new technologies and QbD (quality by design) aspects of manufacturing and control strategies. Includes new perspectives on pre-clinical and clinical development, regulatory considerations, safety and quality. Discusses regulatory challenges, gaps, and future considerations for dermal drug delivery systems.



Handbook Of Formulating Dermal Applications


Handbook Of Formulating Dermal Applications
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Author : Nava Dayan
language : en
Publisher: John Wiley & Sons
Release Date : 2016-12-07

Handbook Of Formulating Dermal Applications written by Nava Dayan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-07 with Science categories.


The conceptualization and formulation of skin care products intended for topical use is a multifaceted and evolving area of science. Formulators must account for myriad skin types, emerging opportunities for product development as well as a very temperamental retail market. Originally published as "Apply Topically" in 2013 (now out of print), this reissued detailed and comprehensive handbook offers a practical approach to the formulation chemist's day-to-day endeavors by: Addressing the innumerable challenges facing the chemist both in design and at the bench, such as formulating with/for specific properties; formulation, processing and production techniques; sensory and elegancy; stability and preservation; color cosmetics; sunscreens; Offering valuable guidance to troubleshooting issues regarding ingredient selection and interaction, regulatory concerns that must be addressed early in development, and the extrapolation of preservative systems, fragrances, stability and texture aids; Exploring the advantages and limitations of raw materials; Addressing scale-up and pilot production process and concerns; Testing and Measurements Methods. The 22 chapters written by industry experts such as Roger L. McMullen, Paul Thau, Hemi Nae, Ada Polla, Howard Epstein, Joseph Albanese, Mark Chandler, Steve Herman, Gary Kelm, Patricia Aikens, and Sam Shefer, along with many others, give the reader and user the ultimate handbook on topical product development.



Frontiers In Drug Design Discovery Volume 10


Frontiers In Drug Design Discovery Volume 10
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Author : Atta-ur-Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-02-03

Frontiers In Drug Design Discovery Volume 10 written by Atta-ur-Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-03 with Medical categories.


Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists have contributed chapters focused on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. This book series should prove to be of interest to all pharmaceutical scientists who are involved in research in drug design and discovery and who wish to keep abreast of rapid and important developments in the field. The tenth volume of this series brings together reviews covering topics related to the treatment of neoplasms, systems biology, respiratory diseases among others. Topics included in this volume are: - Recombinant Protein Production: from Bench to Biopharming - Plant Virus Nanoparticles and Virus like Particles (VLPs): Applications in Medicine - MAO Inhibitory Activity Of 4, 5-Dihydro-1 HPyrazole Derivatives: A Platform To Design Novel Antidepressants - Flavonoids Antagonize Effects of Alcohol in Cultured Hippocampal Neurons: A Drug Discovery Study - Hybrid Smart Materials for Topical Drug Delivery: Application of Scaffolds.



Biotechnology


Biotechnology
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Author : Ronald P. Evens
language : en
Publisher: CRC Press
Release Date : 2020-06-04

Biotechnology written by Ronald P. Evens and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-04 with Medical categories.


The over-riding premise for biotechnology in this book is bringing novel products to market to substantially advance patient care and disease mitigation. Biotechnology, over its relatively brief existence of 40 years, has experienced a mercurial growth. The vast educational need for biotechnology information in this rapidly burgeoning field is a basic rationale here. However a more prominent underpinning is that, bringing biotech products to market for patient care involves success in the following four areas of engagement simultaneously - scientific advances for healthcare technologies, novel and varied products for untreated diseases, regulatory authorities, and biotech companies. Features Comprehensive coverage of biotechnology science topics used in development and manufacturing Addresses all the scientific technologies within biotechnology responsible for products on the market and the pipeline Presents business issues such as marketing and sales of the products, as well as companies engaged, and how biotech business has evolved