The B Side Of B Cells
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The B Side Of B Cells
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Author : Maria Manuela Rosado
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-21
The B Side Of B Cells written by Maria Manuela Rosado and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-21 with Medical categories.
Molecular Biology Of B Cells
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Author : Tasuku Honjo
language : en
Publisher: Elsevier
Release Date : 2014-10-09
Molecular Biology Of B Cells written by Tasuku Honjo and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-09 with Science categories.
Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response
Contemporary Immunology B Cells And T Cells
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Author : Josiah Robinson
language : en
Publisher: Murphy & Moore Publishing
Release Date : 2021-11-16
Contemporary Immunology B Cells And T Cells written by Josiah Robinson and has been published by Murphy & Moore Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Medical categories.
B and T cells are significant parts of the adaptive immune response which is also antigen specific immune response. These are the only cells in the body that are able to recognize the epitopes of the antigen and can respond specifically to each antigenic epitope. The B cells are responsible for the production of antibodies; therefore, the humoral immunity depends on the B cells. Cell immunity depends on the T cells. B cells are also known as antigen presenting cells because they present antigens and secrete cytokines. Immune-mediated cell death is carried out by two major subtypes of T cells: CD8+ "killer T cells" and CD4+ "helper" T cells. The aim of this book is to present researches that have transformed this discipline and aided its advancement. It explores all the important aspects of B and T cells. A number of latest researches have been included in this book to keep the readers up-to-date with the global concepts in this area of study.
B Cell Protocols
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Author : Hua Gu
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
B Cell Protocols written by Hua Gu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Science categories.
B-lymphocyte development and function remains an exciting area of research for those interested in the physiology and pathology of the immune system in higher animals. While recent advances in genetics and cellular and molecular biology have provided a large spectrum of powerful new experimental tools in this field, it is both time consuming and often very difficult for a student or just any bench-side worker to identify a reliable experimental protocol in the ocean of the literature. The aim of B Cell Protocols is to provide a collection of diverse protocols ranging from the latest inventions and applications to some classic, but still frequently used methods in B-cell biology. The authors of the various chapters are all highly qualified scientists who are either the inventors or expert users of these methods. Their extensive experience in mastering a particular method provides not only the step-by-step details of a reproducible protocol, but also useful troubleshooting tips that readers will appreciate in their daily work. We hope that this book will be helpful for both beginning and experienced researchers in the field in designing or modifying an experimental approach, and exploring a biological question from multiple angles.
T And B Lymphocytes Recognition And Function
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Author : Fritz Bach
language : en
Publisher: Elsevier
Release Date : 2012-12-02
T And B Lymphocytes Recognition And Function written by Fritz Bach and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
T and B Lymphocytes: Recognition and Function is the 16th volume of the 1979 ICN-UCLA Symposia on Molecular and Cellular Biology. This book is organized into seven sections, encompassing 74 chapters that summarize molecular level progress in the field of immunobiology. It emphasizes cell membrane, techniques developed for its analysis, and varied products of the major histocompatibility complex, as well as other receptors on cells of the immune system. The book starts by describing two approaches for molecular association evaluation. First is the use of artificial membranes or lipid vesicles for the incorporation of antigens for recognition by T-lymphocytes both at the afferent and efferent levels. Second is the chemical crosslinking of cell surface components with a variety of different crosslinking reagents. This is followed by a discussion on the molecular nature of a T-cell receptor that provides insights of the target(s) recognized by T-lymphocytes. Several chapters discuss data dealing with the issue of the apparent differential recognition by T- and B-cells while both use the same VH genes. Antiidiotypic sera, together with the activity of ""regulator"" T-cells, are also discussed, with regard to their role in networks of regulation of the immune response. This book presents works demonstrating that human T-lymphocytes can also be cloned and both noncytotoxic proliferating T-lymphocytes and Tc can be so obtained. This is along with the continuing studies regarding heterogenity of B-lymphocytes as well as macrophages. Part V focuses on the interaction between lymphocyte and virus and molecular modifications of viral-infected cells. The subsequent section deals with recognition, reactivities, and function of T- and B-lymphocytes. Considerable chapters in this section discuss T-cell cytotoxicity, dichotomy of MHC control over anti H-Y cytotoxic T-cell responses, mouse alloantibodies, and mixed lymphocyte reactions. The concluding part describes immunological tools, such as synthetic membranes and cloned T-cells with biological function.
Janeway S Immunobiology
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Author : Kenneth Murphy
language : en
Publisher: Garland Science
Release Date : 2010-06-22
Janeway S Immunobiology written by Kenneth Murphy and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Differentiation Of B Lymphocytes
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Author : Christopher J. Paige
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Differentiation Of B Lymphocytes written by Christopher J. Paige and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Rapid progress continues to be made in understanding the molecular and cellular events that comprise B-Iymphocyte differentiation. This is due in part to the high level of inter est shown by many investigators from diverse disciplines, who find this subject suitable for addressing some of the fundamental issues of immunobiology. B-cell developmen tal models are being extensively used to investigate cell-cell interactions, molecular mediators of differentiation and proliferation, differential onset of gene programs, and gene rearrangement and expression, as well as the generation of the immune response itself. Not surprisingly, increased understanding of B-cell differentiation sometimes results from the application of new techniques that permit greater insight into the cells comprising the system and the genetic mechanisms by which these cells express their differentiative potential. However, experimental strategies based upon the novel application of established technologies have also led to the clarification of many issues, as well as to the discov ery of previously unrecognized problems. One problem, well recognized by those active in the field, is how to keep up with significant developments as they appear. The purpose of this book, part of a series devoted to analysing current issues in biology, is to help overcome this problem. No attempt at comprehensive cov erage of all of the issues has been made. Rather, a more thorough analysis of a few topics is presented.
Molecular Biology Of B Cells
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Author : Michael Reth
language : en
Publisher: Elsevier
Release Date : 2004-02-19
Molecular Biology Of B Cells written by Michael Reth and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-02-19 with Medical categories.
Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.
Signal Transduction And The Coordination Of B Lymphocyte Development And Function Ii
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Author : Louis B. Justement
language : en
Publisher: Springer
Release Date : 2012-08-14
Signal Transduction And The Coordination Of B Lymphocyte Development And Function Ii written by Louis B. Justement and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-14 with Medical categories.
This volume provides a review of current research in the field of B cell development and differentiation with particular emphasis on signal transduction processes. The volume is divided into two parts that focus, respectively, on the basic biochemical pathways which regulate B cell biology and the role of signal transduction processes in regulating various aspects of B cell function, development and differentiation. In this second part the molecular processes involved in translating BCR engagement to specific biological outcomes are reviewed. Topics covered in this part include signal transduction via the pre-B cell antigen receptor complex, the control of immunoglobulin gene recombination and allelic exclusion, and molecular regulation of positive and negative selection. These latter chapters present information regarding processes which are critical for the B cell response to foreign antigen that leads to differentiation into antibody secreting plasma.
B Cell Biology In Autoimmunity
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Author : David Ahmad Nemazee
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2003
B Cell Biology In Autoimmunity written by David Ahmad Nemazee and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
B cells play a central role not only in adaptive immunity, but also in autoimmunity. To understand how B cells are normally prevented from reacting to self-tissue, what goes wrong in autoimmunity, and how B cells contribute to it is the aim of this book. This volume includes more than a dozen in-depth reviews by researchers specializing in various aspects of basic B cell biology that have relevance to autoimmune diseases. These up-to-date chapters present the latest information on B cell signal transduction, apoptosis, genetics and molecular biology. Also featured are chapters with special reference to particular autoimmune diseases in which B cells have been shown to play a critical role, such as type 1 diabetes, chronic graft-versus-host disease and lupus erythematosus. Further topics covered include the role of the complement system, rheumatoid factors, and anti-DNA autoantibodies as well as important related areas such as natural autoantibodies, B cell immune tolerance, Toll receptor signaling, and the immunobiology of BAFF/BLyS. Both basic researchers and clinician scientists who wish to understand the role of B lymphocytes in immune tolerance and autoimmunity will benefit from this timely publication.