The Benzodiazepines


The Benzodiazepines
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The Benzodiazepines Current Standards For Medical Practice


The Benzodiazepines Current Standards For Medical Practice
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Author : D.E. Smith
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Benzodiazepines Current Standards For Medical Practice written by D.E. Smith and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.




The Benzodiazepines Crisis


The Benzodiazepines Crisis
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Author : John Peppin
language : en
Publisher: Oxford University Press, USA
Release Date : 2021

The Benzodiazepines Crisis written by John Peppin and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Medical categories.


Misused, abused, diverted, and counterfeited, benzodiazepines have serious potential for substance use disorder, and are among the leading causes of drug-related overdose deaths. Evidence indicates that prolonged use of benzodiazepines causes a wide range of adverse reactions, and withdrawal can be particularly challenging. Nevertheless, these negative aspects have yet to be thoroughly addressed within the medical community and remain virtually unknown to patients. This book offers an in-depth discussion of the downsides of this overused class of drugs and calls for their rational and dramatically reduced usage.



The Benzodiazepines


The Benzodiazepines
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Author : J. Marks
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Benzodiazepines written by J. Marks and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The story of the benzodiazepines is a fascinating one: the synthesis of a long series of inert compounds and the abandonment of the project: months later, the renewal of the project and the discovery that this compound R05-0690 (Librium ®) was a sedative and muscle relaxant in laboratory animals: the recognition that its postulated structure was wrong and that it was in fact a member of an entirely new chemical class: the excitement caused by the discovery of the powerful taming effect of the drug in wild animals: the even greater excitement in medical circles when its dramatic anxiety relieving effects were cstablished in humans: the subsequent enormous world wide usc of drugs of the benzodiazepine group. I have reason to know the story well for during that period I worked in various capacities in research, marketing and manage ment in the British subsidiary of F. Hoffmann-Ia Roche. It was during this period that I became interested in whether dependence on benzodiazepines could occur and if so to what extent, but felt that this could be examined best from outside the concern. Having now retired from Roche back to academic medicine I have taken the opportunity to examine and analyse the evidence.



The Benzodiazepines


The Benzodiazepines
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Author : Silvio Garattini
language : en
Publisher:
Release Date : 1973

The Benzodiazepines written by Silvio Garattini and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with Medical categories.




The Benzodiazepines In Current Clinical Practice


The Benzodiazepines In Current Clinical Practice
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Author : Hugh Lionel Freeman
language : en
Publisher: Royal Society of Medicine Press
Release Date : 1987

The Benzodiazepines In Current Clinical Practice written by Hugh Lionel Freeman and has been published by Royal Society of Medicine Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Benzodiazepines categories.




Benzodiazepines Ii


Benzodiazepines Ii
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Author : Harald Schütz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Benzodiazepines Ii written by Harald Schütz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


" ... this is an excellent compilation of data which should be on the bookshelves of all analysts interested in the benzodiazepines. It is to be hoped that, with the introduction of so many new ben zodiazepines, the author will quickly add these in a second edi tion" (A. C. Moffat in: Trends in Analytical Chemistry, 1983). This review, deputizing for many others, reflects the friendly reception enjoyed by the first volume of Benzodiazepines, which was published in 1982 and apparently closed a gap in the ben zodiazepine literature. In the meantime, Benzodiazepines has established itself as a standard book, as evidenced by numerous letters and quotations. Suggestions were also soon made for a new edition in view of the unusually rapid development in the field of the benzodiazepines. It became quickly obvious, however, that it would not be sufficient to publish a revised second edition, but that a completely new second volume would be required for which, however, the successful previous format could be largely retained. The following considerations seem worth mentioning in connection with the preparation of Volume II: - To ensure continuity with Volume I as far as possible, the list of references was consecutively numbered (references 1 to 3779 in Volume I, references 3780 to 11338 in Volume II). Whereas in Vol. I the substances appear in the sequential order of their historical development they are listed in alphabetical order in Vol. II.



The Benzodiazepines Crisis


The Benzodiazepines Crisis
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Author : John F. Peppin
language : en
Publisher:
Release Date : 2021

The Benzodiazepines Crisis written by John F. Peppin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.


"Benzodiazepines were developed to treat legitimate medical needs. However, unbridled success and prescribing beyond their intended duration of use and the available data has led to excessive prescribing, extended utilization beyond good therapeutic practice, and unintended adverse effects and substance use disorder. This book is the first to bring to light and discuss the largely unrecognized and enigmatic problem of an exceedingly prolonged withdrawal syndrome from benzodiazepines that can persist for months or years in susceptible patients, and the medical need for better evidence-based prescribing of benzodiazepines, and a call for the recognition and better treatment of the prolonged withdrawal syndrome"--



The Benzodiazepines


The Benzodiazepines
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Author : J. Marks
language : en
Publisher:
Release Date : 1978-05-31

The Benzodiazepines written by J. Marks and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978-05-31 with categories.




The Benzodiazepines Patterns Of Use


The Benzodiazepines Patterns Of Use
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Author : S. F. Price
language : en
Publisher: Library, Addiction Research Foundation
Release Date : 1975

The Benzodiazepines Patterns Of Use written by S. F. Price and has been published by Library, Addiction Research Foundation this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Benzodiazepines categories.


248 references to literature dealing with who uses the benzodiazepines; reasons for use; and legal, medical, and sociological factors influencing use. Includes journal articles, books, official records, theses, papers presented, and reports published between 1961-1975. Entries include bibliographical information, number of references, keywords, and annotations. Keyword, author indexes.



Benzodiazepines


Benzodiazepines
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Author : H. Schütz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Benzodiazepines written by H. Schütz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


To comment at length on the importance of the benzodiazepines seems superfluous within the scope of this preface. No other class of active substances has experienced an even approximately compa rable advance in the past two decades. It is therefore not surprising that the formerly dominant barbiturates and bromocarbamides have had to give way in many fields to the benzodiazepines, which now rank first (Proudfoot and Park [1828]). Closely linked with the great therapeutic importance of the benzodia zepines are analytical problems. Detection and the determination of blood levels can be necessary under therapeutic aspects, for instance in working out optimally effective levels in the treatment of epileptic conditions ("drug monitoring"), but also in connection with questions at issue in toxicology and traffic medicine. A toxicological analysis can be subdivided into the following steps: Detection (identification including screening) Determination (e. g. blood, plasma or serum levels) Interpretation of the analytical results. This book is intended as a contribution to each of these chapters: The part "Analytical Data" (pp.I-122) gives a comprehensive collec tion of data, e.g. general and chromatographic data (TLC, GLC) as well as spectra (UV, IR, MS) of 19 commercial preparations, 23 important metabolites and 18 hydrolysis derivatives. Information about biotransformation and the possible formation of aminobenzo phenone derivatives is also given. The most important analytical methods are presented in an extensive review on pp.123-204 in order to make it possible to select the optimum method on the basis of the essential data.