The Bioinformatics Times

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Practical Oncologic Molecular Pathology

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Author : Yi Ding
language : en
Publisher: Springer Nature
Release Date : 2021-07-10

Practical Oncologic Molecular Pathology written by Yi Ding and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-10 with Medical categories.

This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology. Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals.

Bioinformatics

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Author : Thomas Dandekar
language : en
Publisher: Springer Nature
Release Date : 2023-03-02

Bioinformatics written by Thomas Dandekar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-02 with Science categories.

This book offers a gripping introduction to the fastest growing field of biology with easy-to-follow examples and a well-prepared appendix for the reader to cook up and experience everything right away. The book gets the reader started with the basics, such as how to easily find sequence information and then analyze it. In further chapters, the authors go into the various analysis options from RNA, DNA and proteins to entire metabolic pathways. Exciting examples from biology are chosen in each chapter to illustrate the analysis. Each chapter concludes with an exercise section that immediately puts what has been learned to use. The subject of this book is a must for any biology student, whether undergraduate or graduate, as bioinformatics is now unearthing amazing insights into the molecular basis of all living things. Computer science students and other students from related sciences will get a good introduction to bioinformatics, as biology and current topics (e.g. AI) are systematically introduced step by step alongside the software. Discover the key to life together with the authors and learn to understand the language of life. This book is a translation of the original German 2nd edition Bioinformatik by Thomas Dandekar and Meik Kunz, published by Springer-Verlag GmbH Germany, part of Springer Nature in 2021. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.

Genes And Behaviour

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Author : David J. Hosken
language : en
Publisher: John Wiley & Sons
Release Date : 2019-02-06

Genes And Behaviour written by David J. Hosken and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-06 with Science categories.

Provides a broad snapshot of recent findings showing how the environment and genes influence behavior The great debate of nature versus nurture rages on — but our understanding of the genetic basis of many behaviors has expanded over the last decade, and there is now very good evidence showing that seemingly complex behaviours can have relatively simple genetic underpinnings, but also that most behaviours have very complicated genetic and environmental architecture. Studies have also clearly shown that behaviors, and other traits, are influenced not just by genes and the environment, but also by the statistical interaction between the two. This book aims to end the nature versus nurture argument by showing that behaviors are nature and nurture and the interaction between the two, and by illustrating how single genes can explain some of the variation in behaviors even when they are seemingly complex. Genes and Behaviour: Beyond Nature-Nurture puts to rest the nature versus nurture dichotomy, providing an up-to-date synopsis of where we are, how far we've come and where we are headed. It considers the effects of a dual-inheritance of genes and culture, and genes and social environment, and highlights how indirect genetic effects can affect the evolution of behavior. It also examines the effect of non-self genes on the behavior of hosts, shines a light on the nature and nurturing of animal minds and invites us to embrace all the complexity nature and nurture generates, and more. Explores exciting new findings about behavior and where we go from here Features contributions by top scholars of the subject Seeks to end the nature versus nurture debate forever Genes and Behaviour: Beyond Nature-Nurture is a unique, and eye-opening read that will appeal to Ph.D. Students, post-doctoral fellows, and researchers in evolution and behavior. Additionally, the book will also be of interest to geneticists, sociologists and philosophers.

Forward Time Population Genetics Simulations

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Author : Bo Peng
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-14

Forward Time Population Genetics Simulations written by Bo Peng and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-14 with Science categories.

The only book available in the area of forward-time population genetics simulations—applicable to both biomedical and evolutionary studies The rapid increase of the power of personal computers has led to the use of serious forward-time simulation programs in genetic studies. Forward-Time Population Genetics Simulations presents both new and commonly used methods, and introduces simuPOP, a powerful and flexible new program that can be used to simulate arbitrary evolutionary processes with unique features like customized chromosome types, arbitrary nonrandom mating schemes, virtual subpopulations, information fields, and Python operators. The book begins with an overview of important concepts and models, then goes on to show how simuPOP can simulate a number of standard population genetics models—with the goal of demonstrating the impact of genetic factors such as mutation, selection, and recombination on standard Wright-Fisher models. The rest of the book is devoted to applications of forward-time simulations in various research topics. Forward-Time Population Genetics Simulations includes: An overview of currently available forward-time simulation methods, their advantages, and shortcomings An overview and evaluation of currently available software A simuPOP tutorial Applications in population genetics Applications in genetic epidemiology, statistical genetics, and mapping complex human diseases The only book of its kind in the field today, Forward-Time Population Genetics Simulations will appeal to researchers and students of population and statistical genetics.

Machine Learning And Deep Learning In Real Time Applications

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Author : Mahrishi, Mehul
language : en
Publisher: IGI Global
Release Date : 2020-04-24

Machine Learning And Deep Learning In Real Time Applications written by Mahrishi, Mehul and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-24 with Computers categories.

Artificial intelligence and its various components are rapidly engulfing almost every professional industry. Specific features of AI that have proven to be vital solutions to numerous real-world issues are machine learning and deep learning. These intelligent agents unlock higher levels of performance and efficiency, creating a wide span of industrial applications. However, there is a lack of research on the specific uses of machine/deep learning in the professional realm. Machine Learning and Deep Learning in Real-Time Applications provides emerging research exploring the theoretical and practical aspects of machine learning and deep learning and their implementations as well as their ability to solve real-world problems within several professional disciplines including healthcare, business, and computer science. Featuring coverage on a broad range of topics such as image processing, medical improvements, and smart grids, this book is ideally designed for researchers, academicians, scientists, industry experts, scholars, IT professionals, engineers, and students seeking current research on the multifaceted uses and implementations of machine learning and deep learning across the globe.

Bioinformatics

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Author : Horacio Pérez-Sánchez
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-11-28

Bioinformatics written by Horacio Pérez-Sánchez and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-28 with Computers categories.

This book is divided into different research areas relevant in Bioinformatics such as biological networks, next generation sequencing, high performance computing, molecular modeling, structural bioinformatics, molecular modeling and intelligent data analysis. Each book section introduces the basic concepts and then explains its application to problems of great relevance, so both novice and expert readers can benefit from the information and research works presented here.

Human Computer Interaction Interaction In Context

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Author : Masaaki Kurosu
language : en
Publisher: Springer
Release Date : 2018-07-10

Human Computer Interaction Interaction In Context written by Masaaki Kurosu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-10 with Computers categories.

The 3 volume-set LNCS 10901, 10902 + 10903 constitutes the refereed proceedings of the 20th International Conference on Human-Computer Interaction, HCI 2018, which took place in Las Vegas, Nevada, in July 2018. The total of 1171 papers and 160 posters included in the 30 HCII 2018 proceedings volumes was carefully reviewed and selected from 4346 submissions. HCI 2018 includes a total of 145 papers; they were organized in topical sections named: Part I: HCI theories, methods and tools; perception and psychological issues in HCI; emotion and attention recognition; security, privacy and ethics in HCI. Part II: HCI in medicine; HCI for health and wellbeing; HCI in cultural heritage; HCI in complex environments; mobile and wearable HCI. Part III: input techniques and devices; speech-based interfaces and chatbots; gesture, motion and eye-tracking based interaction; games and gamification.

Web Age Information Management

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Author : Feifei Li
language : en
Publisher: Springer
Release Date : 2014-06-14

Web Age Information Management written by Feifei Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-14 with Computers categories.

This book constitutes the refereed proceedings of the 15th International Conference on Web-Age Information Management, WAIM 2014, held in Macau, China, in June 2014. The 48 revised full papers presented together with 35 short papers were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on information retrieval; recommender systems; query processing and optimization; data mining; data and information quality; information extraction; mobile and pervasive computing; stream, time-series; security and privacy; semantic web; cloud computing; new hardware; crowdsourcing; social computing.

Novel Approaches In Microbiome Analyses And Data Visualization

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Author : Jessica Galloway-Peña
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-06

Novel Approaches In Microbiome Analyses And Data Visualization written by Jessica Galloway-Peña and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-06 with categories.

High-throughput sequencing technologies are widely used to study microbial ecology across species and habitats in order to understand the impacts of microbial communities on host health, metabolism, and the environment. Due to the dynamic nature of microbial communities, longitudinal microbiome analyses play an essential role in these types of investigations. Key questions in microbiome studies aim at identifying specific microbial taxa, enterotypes, genes, or metabolites associated with specific outcomes, as well as potential factors that influence microbial communities. However, the characteristics of microbiome data, such as sparsity and skewedness, combined with the nature of data collection, reflected often as uneven sampling or missing data, make commonly employed statistical approaches to handle repeated measures in longitudinal studies inadequate. Therefore, many researchers have begun to investigate methods that could improve incorporating these features when studying clinical, host, metabolic, or environmental associations with longitudinal microbiome data. In addition to the inferential aspect, it is also becoming apparent that visualization of high dimensional data in a way which is both intelligible and comprehensive is another difficult challenge that microbiome researchers face. Visualization is crucial in both the analysis and understanding of metagenomic data. Researchers must create clear graphic representations that give biological insight without being overly complicated. Thus, this Research Topic seeks to both review and provide novels approaches that are being developed to integrate microbiome data and complex metadata into meaningful mathematical, statistical and computational models. We believe this topic is fundamental to understanding the importance of microbial communities and provides a useful reference for other investigators approaching the field.

Genomics And Systems Biology Of Mammalian Cell Culture

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Author : Wei-Shou Hu
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-03-16

Genomics And Systems Biology Of Mammalian Cell Culture written by Wei-Shou Hu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-16 with Science categories.

Transcriptome Analysis, by Frank Stahl, Bernd Hitzmann, Kai Mutz, Daniel Landgrebe, Miriam Lübbecke, Cornelia Kasper, Johanna Walter und Thomas Scheper Transcriptome Data Analysis for Cell Culture Processes, by Marlene Castro-Melchor, Huong Le und Wei-Shou Hu Modeling Metabolic Networks for Mammalian Cell Systems: General Considerations, Modeling Strategies, and Available Tools, by Ziomara P. Gerdtzen Metabolic Flux Analysis in Systems Biology of Mammalian Cells, by Jens Niklas und Elmar Heinzle Advancing Biopharmaceutical Process Development by System-Level Data Analysis and Integration of Omics Data, by Jochen Schaub, Christoph Clemens, Hitto Kaufmann und Torsten W. Schulz Protein Glycosylation and Its Impact on Biotechnology, by Markus Berger, Matthias Kaup und Véronique Blanchard Protein Glycosylation Control in Mammalian Cell Culture: Past Precedents and Contemporary Prospects, by Patrick Hossler Modeling of Intracellular Transport and Compartmentation, by Uwe Jandt und An-Ping Zeng Genetic Aspects of Cell Line Development from a Synthetic Biology Perspective, by L. Botezatu, S. Sievers, L. Gama-Norton, R. Schucht, H. Hauser und D. Wirth.