The Biology And Molecular Genetics Of Lung Cancer


The Biology And Molecular Genetics Of Lung Cancer
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The Biology And Molecular Genetics Of Lung Cancer


The Biology And Molecular Genetics Of Lung Cancer
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Author : Adi F. Gazdar
language : en
Publisher: R G Landes Company
Release Date : 1994-01-01

The Biology And Molecular Genetics Of Lung Cancer written by Adi F. Gazdar and has been published by R G Landes Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-01-01 with Technology & Engineering categories.


Intended for oncologists, this book presents knowledge that provides insights into the molecular basis and pathogenesis of lung cancer. It discusses the application of knowledge from the laboratory to practice, allowing the development of rational approaches to lung cancer diagnosis and clinical management. It also focuses on topics that have actual or potential clinical applications. Topics discussed include: the impact of lung cancer; the respiratory epithelium and its tumours; and bad genes and bad habits.



Molecular Genetics Of Lung Cancer


Molecular Genetics Of Lung Cancer
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Author : John D. Minna
language : en
Publisher:
Release Date : 1988

Molecular Genetics Of Lung Cancer written by John D. Minna and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Lungs categories.




The Molecular Genetics Of Lung Cancer


The Molecular Genetics Of Lung Cancer
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Author : David N Cooper
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-11-20

The Molecular Genetics Of Lung Cancer written by David N Cooper and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-20 with Medical categories.


Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk. The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.



The Molecular Genetics Of Lung Cancer


The Molecular Genetics Of Lung Cancer
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Author : David Cooper
language : en
Publisher: Springer
Release Date : 2009-09-02

The Molecular Genetics Of Lung Cancer written by David Cooper and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-02 with Medical categories.


Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk. The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.



Molecular Biology Of Cancer


Molecular Biology Of Cancer
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Author : Fiona Macdonald
language : en
Publisher: Taylor & Francis
Release Date : 2004-06-02

Molecular Biology Of Cancer written by Fiona Macdonald and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-06-02 with Juvenile Nonfiction categories.


Molecular Biology of Cancer has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It continues to provide a detailed overview of the process which lead to the development and proliferation of cancer cells, including the techniques available for their study. It also describes the means by which tumor suppressor genes and oncogenes may be used in the diagnosis and in determining the prognosis of a wide variety of cancers, including breast, genitourinary, lung and gastrointestinal cancer.



The Genetics Of Cancer


The Genetics Of Cancer
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Author : B.A. Ponder
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Genetics Of Cancer written by B.A. Ponder and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.



Cancer Of The Lung


Cancer Of The Lung
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Author : Alan Weitberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-10-04

Cancer Of The Lung written by Alan Weitberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-04 with Medical categories.


Alan B. Weitberg, MD, and a panel of internationally recognized basic scientists and clinicians present a comprehensive discussion of lung cancer, including a practice-oriented review of its diagnosis, evaluation, and treatment. The contributors offer not only an understandable description of its molecular origins-an essential key to developing future therapies and preventive measures-but also rigorously discuss well-tested approaches, as well as those that are currently being evaluated for future use in both the laboratory and clinic. The book also elucidates the creation and effective deployment of treatment guidelines introduced by third party payers to improve clinical outcomes, even while lowering healthcare costs.



Recent Advances In The Molecular Genetics And Precision Medicine Of Lung Carcinoma


Recent Advances In The Molecular Genetics And Precision Medicine Of Lung Carcinoma
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Author : Mehdi Pirooznia
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-25

Recent Advances In The Molecular Genetics And Precision Medicine Of Lung Carcinoma written by Mehdi Pirooznia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-25 with Science categories.


Lung Carcinoma is the 2nd most common cancer worldwide, with more than 2.2 million cases recorded globally in the year 2020, as well as 1.8 million deaths. It is the most common cancer in men and the 2nd most common cancer in women, with an estimated lifetime risk of developing the disease of 1 in 15 for men and 1 in 17 for women. Whilst being the most prevalent cancer, it is important to note that smoking is the single biggest risk factor for developing Lung Cancer, with over 70% of cases being estimated to have been caused by tobacco smoke, and excessive smoking potentially leading to as much as a 25x increase in the likelihood of the disease developing. Mortality rates have been steadily dropping globally due to declining smoking rates, especially in younger generations who are now more aware of the potential dangers, but also because of the increasing advancements being made in our understanding of the disease. Improved screening methods mean many more cases are now caught earlier than they would otherwise have been, and our ever-advancing ranges of treatments can begin earlier than they could have previously. Recent advances in sequencing technology, computational approaches, and our biological understanding of lung cancer have revolutionized how we diagnose, prognosticate, and treat lung carcinoma. Genetic studies into this disease have revealed a plethora of information which can be used to combat the Cancer, such as novel biomarkers and gene signatures, as well as opening the door to more of a ‘personalized medicine’ approach.



Cancer Cytogenetics


Cancer Cytogenetics
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Author : Sverre Heim
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-20

Cancer Cytogenetics written by Sverre Heim and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-20 with Medical categories.


Cancer Cytogenetics, 3rd Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area and incorporates a vast amount of new data from the latest basic and clinical investigations. Edited by two leading experts, and now involving a new panel of international experts, the book offers an authoritative description of neoplastic processes at the chromosomal level of genomic organization. Researchers in cytogenetics, medical and molecular genetics, cellular and molecular biology, cancer research, clinical oncology, and hematology will find this reference both thorough and authoritative.



Clinical And Biological Basis Of Lung Cancer Prevention


Clinical And Biological Basis Of Lung Cancer Prevention
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Author : Yves Martinet
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06

Clinical And Biological Basis Of Lung Cancer Prevention written by Yves Martinet and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Lung cancer is a disease with pandemic public health implications as it is now the leading cause of cancer mortality throughout the world. This book results from two recent International Association for the Study of Lung Cancer (IASLC) Workshops on lung cancer prevention. It strikes a balance between considering public health approaches to tobacco control and population-based screening, advances in clinical evaluation of chemoprevention approaches, and the biology of lung carcinogenesis. Indeed, while the science of smoking cessation is evolving as new pharmacological tools are moving into clinical evaluation, the current impact of molecular diagnostics is profound. The rapidly-evolving diagnostic technologies are revolutionizing basic scientific investigation of cancer, and this trend is expected to soon spill over into the clinical practice of medicine. The evolution of economical diagnostic platforms to allow for direct bronchial epithelial evaluation in high-risk populations promises to improve the diagnostic lead-time for this disease. The hope is that enough progress will occur to permit lung cancer detection in advance of clinical cancer so that the disease can be addressed early on, while it is still confined to the site of origin. Chemoprevention, which is designed to intervene in the early phase of carcinogenesis prior to any subjective clinical manifestation of a cancer, is also generating greater research interest. Moreover, the benefit of aerosolized administration of chemoprevention agents over conventional oral administration has strong appeal and may result in the reduction of the incidence of cancer when combined with new diagnostic technologies.