The Biology Of Human Longevity
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The Biology Of Human Longevity
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Author : Caleb E. Finch
language : en
Publisher: Elsevier
Release Date : 2010-07-28
The Biology Of Human Longevity written by Caleb E. Finch and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-28 with Medical categories.
Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure. This timely and topical book will be of interest to anyone studying aging from any scientific angle. Author Caleb Finch is a highly influential and respected scientist, ranked in the top half of the 1% most cited scientists Provides a novel synthesis of existing ideas about the biology of longevity and aging Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition
Longevity
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Author : James R. Carey
language : en
Publisher: Princeton University Press
Release Date : 2021-01-12
Longevity written by James R. Carey and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-12 with Science categories.
Despite our deep interest in mortality, little is known about why some individuals live to middle age and others to extreme old age. Life span, mortality, and aging present some of the most profound mysteries in biology. In Longevity, James Carey draws on unprecedented data to develop a biological and demographic framework for identifying the key factors that govern aging, life span, and mortality in humans and other animals. Carey presents the results of a monumental, twelve-year, National Institute on Aging-funded research project on the determinants of longevity using data from the life tables of five million Mediterranean fruit flies, the most comprehensive set of life table studies ever on the mortality dynamics of a single species. He interprets the fruit fly data within the context of human aging and the aging process in general to identify the determinants of mortality. Three key themes emerge: the absence of species-specific life span limits, the context-specific nature of the mortality rate, and biodemographic linkages between longevity and reproduction. A powerful foundation for the emerging field of biodemography and a rich framework for considering the future of human life span, Longevity will be an indispensable resource for readers from a range of fields including population biology, demography, gerontology, ecology, evolutionary biology, and medical research.
The Quest For Human Longevity
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Author : Lewis D. Solomon
language : en
Publisher: Routledge
Release Date : 2017-12-02
The Quest For Human Longevity written by Lewis D. Solomon and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-02 with Political Science categories.
"Many scientists today are working to retard the aging process in humans so as to increase both life expectancy and the quality of life. Over the past decade impressive results have been achieved in targeting the mechanisms and pathways of aging. In The Quest for Human Longevity, Lewis D. Solomon considers these scientific studies by exploring the principal biomedical anti-aging techniques. The book also considers cutting edge research on mental enhancements and assesses the scientific doubts of skeptics. The Quest for Human Longevity is also about business. Solomon examines eight corporations pursuing various age-related interventions, profiling their scientific founders and top executives, and examining personnel, intellectual property, and financing for each firm. Academic scientists form the link between research and commerce. Solomon notes that the involvement of university scientists and researchers follows one of two models. The first is a traditional model in which scientists leave academia to work for a corporation or remain in academia and obtain business support for their research. The second is a modern model in which scientists use their intellectual property as a catalyst for acquiring equity interests in the firms they organize. Critics have pointed to the dangers of commercialized science, but Solomon's analysis, on balance, finds that the benefits outweigh the costs and that problems of secrecy and conflicts of interest can be addressed. If scientists succeed in unlocking the secrets of aging and developing drugs or therapies that will allow us to live decades longer, the consequences for society will include profound social, political, economic, and ethical questions. Solomon deals with the public policy aspects of significant life extension and looks at the conflict between those who advocate the acceptance of mortality and the partisans of life. The Quest for Human Longevity will be of interest to policymakers, sociologists, scientists, and studen"
Human Longevity
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Author : Raymond C. Valentine
language : en
Publisher: CRC Press
Release Date : 2014-09-18
Human Longevity written by Raymond C. Valentine and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-18 with Medical categories.
More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman’s famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging. Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membrane oxidation introduced in this book. This concept is consistent with recent discoveries showing that mitochondria-targeted antioxidants prevent Huntington’s disease, Parkinson’s disease, and traumatic brain disease in animal models of neurodegeneration. This book explores a unified theory of aging based on bioenergetics. It covers a variety of topics including an introduction to the science of human aging, the Darwinian selection of membranes enabling longevity, a revised mitochondrial membrane hypothesis of aging, and various mechanisms that protect human mitochondrial membranes, thereby enabling longevity.
Aging And Human Longevity
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Author : M.-F. Schulz-Aellen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Aging And Human Longevity written by M.-F. Schulz-Aellen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The proportion of elderly people continues to increase in the western world-nearly a quarter of the population will be over 65 years by the year 2050. Since aging is accompanied by an increase in diseases and by a deterioration in well-being, finding solutions to these social, medical and psychological problems is necessarily a major goal for society. Scientists and medical practitioners are therefore faced with the urgent task of increasing basic knowledge of the biological processes that cause aging. More resources must be put into this research in order to achieve better understanding of the cellular mechanisms that underlie the differences in life span between species and to answer the difficult questions of why some individuals age more quickly than others, and why some develop liver problems, some have heart problems, and others brain problems. The results of such a wide program of research will provide important information about the causes of many life-threatening and/ or debilitating diseases of old age; it will help find ways to prevent some of the ailments that result from aging, and it may well lead to discoveries enabling the prolongation of human life.
Aging And Human Longevity
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Author : Marie-Francoise Schulz-Aellen
language : en
Publisher: Birkhäuser
Release Date : 1997
Aging And Human Longevity written by Marie-Francoise Schulz-Aellen and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Science categories.
The proportion of elderly people continues to increase in the western world-nearly a quarter of the population will be over 65 years by the year 2050. Since aging is accompanied by an increase in diseases and by a deterioration in well-being, finding solutions to these social, medical and psychological problems is necessarily a major goal for society. Scientists and medical practitioners are therefore faced with the urgent task of increasing basic knowledge of the biological processes that cause aging. More resources must be put into this research in order to achieve better understanding of the cellular mechanisms that underlie the differences in life span between species and to answer the difficult questions of why some individuals age more quickly than others, and why some develop liver problems, some have heart problems, and others brain problems. The results of such a wide program of research will provide important information about the causes of many life-threatening and/ or debilitating diseases of old age; it will help find ways to prevent some of the ailments that result from aging, and it may well lead to discoveries enabling the prolongation of human life.
Human Longevity
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Author : David W. E. Smith
language : en
Publisher: Oxford University Press, USA
Release Date : 1993
Human Longevity written by David W. E. Smith and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Health & Fitness categories.
This absorbing, balanced account of human longevity draws together information from the fields of medicine, biology, demography, epidemiology, gerontology, and sociology. It describes the history and present status of human longevity and deals in logical sequence with the questions this subject raises. The book illustrates how life expectancy has increased in most countries due, in part, to changing causes of death. It examines the biological determinants of longevity and analyzes social and behavioral factors that may reduce longevity. The book covers the reasons why women live longer than men. It asks why the maximum human life span is nearly twice that of any other warm-blooded animal and much longer than required for reproductive success, and it discusses factors that were involved in the evolution of longevity. It presents predictable increases in human life expectancy and explores the possibility that the maximum human life expectancy may become even longer. Accessible, comprehensive, and original, this book provides a multidisciplinary synthesis of ideas and conclusions about human longevity. It will have wide appeal to professionals in the many areas concerned with longevity as well as lay readers.
The Biology Of Human Ageing
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Author : Society for the Study of Human Biology
language : en
Publisher: Cambridge University Press
Release Date : 1986-03-20
The Biology Of Human Ageing written by Society for the Study of Human Biology and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-03-20 with Science categories.
This book discusses the findings of a joint symposium held in 1984 to consider human ageing and longevity from an interdisciplinary point of view.
Aging And Human Longevity
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Author : Marie-Françoise Schulz-Aellen
language : en
Publisher: Birkhauser
Release Date : 1997-01-01
Aging And Human Longevity written by Marie-Françoise Schulz-Aellen and has been published by Birkhauser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-01-01 with Aging categories.
This book combines a scientific and medical description of aging with a critical review of ways to prolong life. The first part gives an overview of the complex biological mechanisms of aging and of the consequences of tissue and system aging in humans. The role of genetic and environmental factors that influence the rate of aging in several species is discussed. The second part of this book evaluates the various means, including life styles, behavioral variables, medical interventions and vitamin supplementation, that may slow down the physiological and psychological effects of aging. Biotechnology and gene therapy are also becoming a part of medical interventions to prolong life. This book is aimed at readers with some knowledge of biology and medicine, as well as to a larger audience eager to know more about how to live a healthy, happy and productive life in their old age.
Human Longevity From Antiquity To The Modern Lab
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Author :
language : en
Publisher: Greenwood
Release Date : 1987-03-18
Human Longevity From Antiquity To The Modern Lab written by and has been published by Greenwood this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-03-18 with Health & Fitness categories.
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