The Biology Of Multiple Sclerosis
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The Biology Of Multiple Sclerosis
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Author : Professor Gregory Atkins
language : en
Publisher:
Release Date : 2014-05-14
The Biology Of Multiple Sclerosis written by Professor Gregory Atkins and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Multiple sclerosis categories.
Multiple sclerosis is the most common debilitating neurological disease in people under the age of forty in the developed world. Many publications cover medical and clinical approaches to the disease; however, The Biology of Multiple Sclerosis provides a clear and concise up-to-date overview of the scientific literature on the various theories of MS pathogenesis. Covering the main elements of scientific research into multiple sclerosis, the book contains chapters on the neuropathology of the disease as well as an account of the most extensively used animal model experimental autoimmune encephalomyelitis. The book contains chapters regarding the role of viruses in the development of multiple sclerosis. Viruses have long been implicated and chapters on animal models based on virus infection, as well as their possible role in the etiology of MS, are included. Of interest to MS researchers, the book is written to also be of value to postgraduate and medical students.
The Biology Of Multiple Sclerosis
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Author : Gregory Atkins
language : en
Publisher: Cambridge University Press
Release Date : 2012-11-08
The Biology Of Multiple Sclerosis written by Gregory Atkins and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-08 with Medical categories.
A clear and concise up-to-date overview of the scientific research literature related to the biology of multiple sclerosis.
Molecular Biology Of Multiple Sclerosis
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Author : W. C. Russell
language : en
Publisher:
Release Date : 1997
Molecular Biology Of Multiple Sclerosis written by W. C. Russell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
Multiple sclerosis (MS) is a devastating demyelinating disease with complex aetiology which defies simple molecular description. Molecular Biology of Multiple Sclerosis provides a compendium of information on the molecular aspects of the disease. It embraces contributions on the biology and pathology of the cells of the central nervous system as well as recent advances in our understanding of the relevant biochemistry, immunology, genetics and virology. With this enhanced knowledge the prospects for transplantation and repair of the damaged myelin as well as approaches to rational therapy are considered. Studies in MS embrace a wide spectrum of disciplines and this volume will be indispensible to neurologist, molecular biologists, biochemists, microbiologists, geneticists and immunologists with an interest in MS.
Understanding Multiple Sclerosis
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Author : Melissa Stauffer
language : en
Publisher: Univ. Press of Mississippi
Release Date : 2009-09-18
Understanding Multiple Sclerosis written by Melissa Stauffer and has been published by Univ. Press of Mississippi this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-18 with Health & Fitness categories.
Two-and-a-half million people world-wide and 400,000 Americans suffer from the chronic disease multiple sclerosis. Understanding Multiple Sclerosis presents both general information about MS and valuable, specific advice. Who gets MS? What are its symptoms? What are its effects on the bodies and minds of people afflicted? How does one plan for the future after a diagnosis? From basic biology to new advances in treatment, Understanding Multiple Sclerosis covers the topics most relevant to people with MS and to their families and friends. Chapters provide an introduction to genetic, demographic, and geographic factors; basic biology of MS, with descriptions of both the central nervous system and the immune system; characteristic symptoms of MS; diagnostic criteria and different types of MS treatments, over-the-counter medications, and alternative medicines; lifestyle adjustments and coping strategies, along with advice on long-term health insurance and financial planning; and current and ongoing MS research and advances.
Molecular Basis Of Multiple Sclerosis
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Author : Roland Martin
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-14
Molecular Basis Of Multiple Sclerosis written by Roland Martin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-14 with Medical categories.
Despite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited. Consequently, the current strategies for treatment and management of patients are limited in their efficacy. The mechanisms of tissue protection and repair are probably even less understood. One reason for these limitations is the enormous complexity of the disease and every facet of its pathogenesis, the mechanisms of tissue injury, the diagnostic procedures and finally the efficacy of treatments and their side effects. The aim of this book is to review the most recent advances made in this highly complex field.
Handbook Of Multiple Sclerosis
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Author : Stuart D. Cook
language : en
Publisher: CRC Press
Release Date : 2006-03-13
Handbook Of Multiple Sclerosis written by Stuart D. Cook and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-13 with Medical categories.
Filled with an abundance of reader-friendly and quick-reference tables and figures, this Fourth Edition spans the etiology, epidemiology, clinical features, diagnosis, pathology, and treatment of multiple sclerosis (MS). Surpassing other texts on the topic, this reference provides recommendations and research updates from renowned authorities in th
Emerging And Evolving Topics In Multiple Sclerosis Pathogenesis And Treatments
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Author : Anne C. La Flamme
language : en
Publisher: Springer
Release Date : 2015-10-07
Emerging And Evolving Topics In Multiple Sclerosis Pathogenesis And Treatments written by Anne C. La Flamme and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-07 with Medical categories.
Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment. While some of these advances have been through new approaches and ideas that have emerged in the last decade such as the newly identified protective role that amyloid proteins may play in MS or the use of helminths to treat autoimmune diseases, others have evolved from previous theories and ideas that have only now gained momentum and a deeper understanding such as the role of HLA or gender in MS susceptibility. This book covers these emerging and evolving topics and highlights the substantial advancements made in elucidation of the factors regulating susceptibility or disease progression, identification of new ways to monitor or predict MS pathology, and development of new strategies for treating MS.
Multiple Sclerosis
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-08-10
Multiple Sclerosis written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-08-10 with Medical categories.
Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.
Multiple Sclerosis
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Author : Robert Weissert
language : en
Publisher: Humana
Release Date : 2016-10-19
Multiple Sclerosis written by Robert Weissert and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-19 with Science categories.
This detailed volume covers molecular biology, cellular biology, biomarkers, imaging, and neuropathological methods and techniques to explore multiple sclerosis (MS), with a special emphasis on disease models. With so much effort needed to elucidate basic disease mechanisms, to clone disease relevant genes, to define novel biomarkers, and to discover novel and improved therapeutic and curative treatments, this book serves to aid researchers in accomplishing these enormous goals. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and easy to use, Multiple Sclerosis: Methods and Protocols will empower the reader to perform novel research regarding pathophysiology and treatment for MS.
Cellular And Molecular Mechanisms In Pathogenesis Of Multiple Sclerosis
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Author : Edwin Wan
language : en
Publisher: MDPI
Release Date : 2020-11-25
Cellular And Molecular Mechanisms In Pathogenesis Of Multiple Sclerosis written by Edwin Wan and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Science categories.
Multiple sclerosis (MS) is one of the most common neurological disorders in young adults. The etiology of MS is not known, but it is generally accepted that it is autoimmune in nature. Our knowledge of the pathogenesis of MS has increased tremendously in the past decade through clinical studies and the use of experimental autoimmune encephalomyelitis (EAE), a model that has been widely used for MS research. Major advances in the field, such as understanding the roles of pathogenic Th17 cells, myeloid cells, and B cells in MS/EAE, as well as cytokine and chemokine signaling that controls neuroinflammation, have led to the development of potential and clinically approved disease-modifying agents (DMAs). There are many aspects related to the initiation, relapse and remission, and progression of MS that are yet to be elucidated. For instance, what are the genetic and environmental risk factors that promote the initiation of MS, and how do these factors impact the immune system? What factors drive the progression of MS, and what are the roles of peripheral immune cells in disease progression? How do the CNS-infiltrated immune cells interact with the CNS-resident glial cells when the disease progresses? What is the role of microbiome in MS? Can we develop animal models that better represent subcategories of MS? Understanding the cellular and molecular mechanisms that govern the pathogenesis of MS will help to develop novel and more specific therapeutic strategies that will ultimately improve clinical outcomes of the treatments. This Special Issue of Cells has published original research articles, a retrospective clinical report, and review articles that investigate the cellular and molecular basis of MS.