The C I

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The C I

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Author : Les Roberts
language : en
Publisher: Down & Out Books
Release Date : 2023-03-13

The C I written by Les Roberts and has been published by Down & Out Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-13 with Fiction categories.

Slovenian-American Jericho Paich finds himself under arrest by snarling Cleveland police cop Keenan Mayo and forced to be a non-paid confidential informant, setting up friends and strangers to be hauled in for illegal drug use. He turns for help to his mother’s live-in lover, ex-marine officer Laird Janiver. The two have never gotten along, but Jerry has nowhere else to turn. Janiver, a studious African American major who recalls how to kill, decides to help. That brings the two men into contact with a cruelly efficient albino drug lord, the suicidal memory of a lovely young college girl at OSU, and a beautiful woman with what might be a very dangerous past.

The Opposite Of Noise

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Author : Benjamin Gilad Ph D
language : en
Publisher: Independently Published
Release Date : 2021-09-24

The Opposite Of Noise written by Benjamin Gilad Ph D and has been published by Independently Published this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-24 with categories.

In the age of too much data and too few breakthroughs, market "noise" is the biggest challenge for executives and managers. Finding growth opportunities requires a powerful filter. This filter is competitive intelligence- market insight that cuts through the din and propels companies to leap forward ahead of all others. It has little to do with more information on competitors. It has everything to do with making every market-facing manager more competitively skilled. In his characteristic blunt and entertaining style, the international expert and CEO of the Academy of Competitive Intelligence provides tools, tips, eye-opening case studies, and a new model to break through "data-driven" hype and change how management looks at competitive intelligence.

The Big Ci Book

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Author : Ben Slavic
language : en
Publisher:
Release Date : 2017

The Big Ci Book written by Ben Slavic and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.

The Ci Driven Ceo A Little Leadership Story About A Powerful Competitive Intelligence Idea

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Author : David J. Kalinowski
language : en
Publisher: Indie Books International
Release Date : 2022-04-07

The Ci Driven Ceo A Little Leadership Story About A Powerful Competitive Intelligence Idea written by David J. Kalinowski and has been published by Indie Books International this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-07 with Business & Economics categories.

This book debunks many myths. There are some common misconceptions about what Competitive Intelligence (CI) is and how it can benefit businesses. The CI-Driven CEO illustrates how CI is an essential function, not an overhead expense, that helps identify opportunities and reduce risk by uncovering critical insights senior executives can use to improve strategic decision making. Escape the data-darkness of the past and follow this guiding light toward the future. In this story, Jack, the imperfect Chief Competitive Officer of Hewitt Games, faces a huge challenge when an unexpected competitor enters the scene and threatens the lifeblood of his company. When he is appointed the interim CEO, he must find a way to create a truly embedded, CI-friendly culture, and develop a strategy to outmaneuver the competition before all is lost.

The Ci Driven Ceo

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Author : Gary Maag
language : en
Publisher:
Release Date : 2022-04-25

The Ci Driven Ceo written by Gary Maag and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-25 with categories.

Biobetters

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Author : Amy Rosenberg
language : en
Publisher: Springer
Release Date : 2015-08-21

Biobetters written by Amy Rosenberg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-21 with Medical categories.

“Biobetters: Protein Engineering to Approach the Curative” discusses the optimization of protein therapeutic products for treatment of human diseases. It is based on the fact that though numerous important therapeutic protein products have been developed for life threatening and chronic diseases that possess acceptable safety and efficacy profiles, these products have generally not been reexamined and modified for an improved clinical performance, with enhancements both to safety and efficacy profiles. Advances in protein engineering, coupled with greatly enhanced understanding of critical product quality attributes for efficacy and safety, make it possible to optimize predecessor products for clinical performance, thereby enhancing patient quality of life and with the potential for great savings in health care costs. Yet despite such knowledge, there is little movement towards such modifications. This book examines engineering protein therapeutic products such that they exhibit an optimal, not just an adequate, clinical performance profile. Two product classes, therapeutic enzymes for lysosomal storage diseases (enzyme replacement therapies, ERT) and monoclonal antibodies (mAbs), are used as examples of what modifications to such proteins could be made to enhance clinical performance, “closer to a cure” as it were. For ERT, the key to optimizing clinical performance is to ensure the ERT is endowed with moieties that target the protein to the relevant target tissue. Thus, for Gaucher Disease, our best example of how to optimize an ERT to address a disease that manifests in specific target tissues (macrophages and monocytes), the enzyme has been extensively modified to target macrophages. For diseases such as Pompe Disease, largely a disorder of muscle, optimal performance of ERT will depend on endowing the enzyme with the ability to be taken up via the Mannose 6 Phosphate Receptor, and so one of the chapters in the book will discuss such approaches. Moreover, a major failure of biotechnology based products is to gain access to the CNS, a key target tissue in numerous diseases. Thus, a chapter has been devoted to strategies to access the CNS. Additionally, immune responses to therapeutic proteins can be highly problematic, eliminating the efficacy of life saving or highly effective protein therapeutics. This is especially poignant in the case of Pompe Disease wherein great improvement in muscle strength and functionality is lost following development of an immune response to the ERT with consequent patient deterioration and death. Thus, a chapter regarding protein engineering, as well as other non-clinical approaches to diminishing immunogenicity is a valuable part of the book. Monoclonal antibodies (mAbs) can be engineered to bind targets relevant to a wide variety of diseases; binding affinity, however, is only part of the equation and one of the chapters will present a molecular assessment approach that balances affinity with pharmacokinetics and manufacturability. As with other proteins immunogenicity can be problematic, being responsible for loss of efficacy of anti-TNF mAbs, often after prolonged successful treatment. The authors will also share their perspective on the consequences of physico-chemical modifications occurring to mAbs once they reach the circulation or their target, a research area open to further development from a protein engineering as well as analytical perspective. This book will also discuss novel platforms for protein therapeutics, technologies that exceed mAbs with respect to potency, and hence, potentially efficacy. These platforms consist largely of repeat domain proteins with very high affinity for their target ligands, but while potentially more efficacious, immunogenicity may be a major problem limiting use. The economics surrounding the issue of biobetters is another high-profile issue - this final chapter will explore the incentives and disincentives for developing biobetters and consider incentives that might make their pursuit more rewarding.

Decisions And Orders

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Author : United States. Bituminous Coal Division
language : en
Publisher:
Release Date : 1943

Decisions And Orders written by United States. Bituminous Coal Division and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1943 with Administrative agencies categories.

The Ci

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Author : Thomas G. Blacklock
language : en
Publisher:
Release Date : 2016-08-01

The Ci written by Thomas G. Blacklock and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-01 with Fiction categories.

The head of a Mexican Drug Cartel kidnaps the administrator of the Drug Enforcement Administration and holds him hostage in a remote area of Northern Mexico. Tom Blaine. Using, a CI, takes a covert team into Mexico to free the administrator and return him to the United States.

Spi Ci International Conference And Exposition 1998

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Author : Technomic
language : en
Publisher: CRC Press
Release Date : 2022-01-26

Spi Ci International Conference And Exposition 1998 written by Technomic and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-26 with Technology & Engineering categories.

This book discusses how the excess value, of the products using braid, is captured in prosthetic limbs, aircraft and automotive components, commercial furniture, and trenchless sewer repair structures. It outlines the braided pultrusion process and also discusses impregnation states.

The C I Desk

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Author : Christopher Lynch
language : en
Publisher: Dog Ear Publishing
Release Date : 2010-12

The C I Desk written by Christopher Lynch and has been published by Dog Ear Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12 with Intelligence officers categories.

Fans of "The Americans" TV series on the FX Network will recognize elements of the show in The CI Desk, Chris Lynch's account of his thirty years as a counterintelligence analyst at the FBI and CIA. "The Americans" creator Joe Weisberg discovered the now-popular "character," the "FBI mail robot," within The CI Desk's pages, and hired Chris Lynch to be a consultant for the show. Since then, the Writers Guild of America and Peabody Award-winning writers of the show have extracted anecdotes, descriptions, and terms from The CI Desk for episodes of "The Americans," including "The Bureau does not feel," "munchkins," and Lynch's own experience of being suddenly and inexplicably summoned to the Director's office. According to Kim Chamberlain of EspionageMagazine.com, "this book lends the personality, depth, and reality to the day-to-day intelligence that seems to be lacking in other works. With a razor-sharp wit, a keen eye for human nature, and a wry sense of humor, The CI Desk is in turn hilarious and saddening. There are some nail-biter moments here (and) a seemingly endless procession of fascinating characters," including moles (such as FBI agent Robert P. Hansson, Lynch's supervisor for two years), mole hunters, penetrations of hostile services, defectors, agent handlers, and the unsung people at headquarters desks in FBI and CIA operations that spanned the globe. The C.I. Desk shows the routine, the thrilling, and the sometimes funny or tragic human side of the counterintelligence work of the FBI and CIA.

The C I

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