The Cellular Secretome And Organ Crosstalk


The Cellular Secretome And Organ Crosstalk
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The Cellular Secretome And Organ Crosstalk


The Cellular Secretome And Organ Crosstalk
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Author : Juergen Eckel
language : en
Publisher: Academic Press
Release Date : 2018-06-12

The Cellular Secretome And Organ Crosstalk written by Juergen Eckel and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-12 with Science categories.


The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health and disease. Communication between different organs involves lipids and other small molecules and a host of proteins and peptides comprising the secretome of different organs (organokinome). More than 600 adipokines have been identified, and an increasing number of hepatokines and myokines have recently been discovered with mostly unknown physiological impact. Importantly, an aberrant signature of the organokinome may be critically underlying a variety of metabolic diseases and may determine the individual susceptibility to disease development. Summarizes our current knowledge on the secretome of different cells and tissues Dissects auto-, para- and endocrine functions of major secreted peptides and proteins Analyzes the secretory malfunction of different cells and its impact for disease development Authored by a leader in the field, presenting a coherent view on this very complex topic



Scientific Principles Of Adipose Stem Cells


Scientific Principles Of Adipose Stem Cells
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Author : Lauren Kokai
language : en
Publisher: Academic Press
Release Date : 2021-08-19

Scientific Principles Of Adipose Stem Cells written by Lauren Kokai and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-19 with Science categories.


Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications



Mesenchymal Stem Cell Derived Exosomes


Mesenchymal Stem Cell Derived Exosomes
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Author : Yaoliang Tang
language : en
Publisher: Academic Press
Release Date : 2015-09-02

Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-02 with Medical categories.


Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies



The Role Of The Muscle Secretome In Health And Disease


The Role Of The Muscle Secretome In Health And Disease
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Author : Céline Aguer
language : en
Publisher: Frontiers Media SA
Release Date : 2020-11-19

The Role Of The Muscle Secretome In Health And Disease written by Céline Aguer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-19 with Science categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Lung Stem Cells In Development Health And Disease


Lung Stem Cells In Development Health And Disease
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Author : Nikolic, Marko Z.
language : en
Publisher: European Respiratory Society
Release Date : 2021-04-01

Lung Stem Cells In Development Health And Disease written by Nikolic, Marko Z. and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-01 with Medical categories.


Most organs in the adult human body are able to maintain themselves and undergo repair after injury; these processes are largely dependent on stem cells. In this Monograph, the Guest Editors bring together leading authors in the field to provide information about the different classes of stem cells present both in the developing and adult lung: where they are found, how they function in homeostasis and pathologic conditions, the mechanisms that regulate their behaviour, and how they may be harnessed for therapeutic purposes. The book focuses on stem cells in the mouse and human lung but also includes the ferret as an increasingly important new model organism. Chapters also discuss how lung tissue, including endogenous stem cells, can be generated in vitro from pluripotent stem cell lines. This state-of-the-art collection comprehensively covers one of the most exciting areas of respiratory science



Stem Cells


Stem Cells
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Author : Khawaja H. Haider
language : en
Publisher: Springer Nature
Release Date : 2021-11-30

Stem Cells written by Khawaja H. Haider and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-30 with Science categories.


In this volume, the contributing authors from top labs involved in stem cell theranostics share the latest advances in the field of stem cell research. The book covers many aspects of stem cell-based therapy and the progress made toward stem cell therapy for liver, ocular, and cardiovascular diseases as well as cancer. This volume serves as a continuation of Prof. Khawaja Husnain Haider’s previously edited books pertaining to stem cells-based therapnostics. This is an ideal book for researchers involved in drug development as well as regenerative medicine and stem cell-based therapy. The secondary audience includes graduate and postgraduate medical students, doctors, cellular pharmacology, drug industry, and researchers involved in using stem cells as ex-vivo disease models for drug development.



Exercise Immunology


Exercise Immunology
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Author : Bente Klarlund Pedersen
language : en
Publisher:
Release Date : 1997-01-01

Exercise Immunology written by Bente Klarlund Pedersen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-01-01 with Exercise categories.




Current Challenges For Targeting Brown Fat Thermogenesis To Combat Obesity


Current Challenges For Targeting Brown Fat Thermogenesis To Combat Obesity
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Author : Takeshi Yoneshiro
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-28

Current Challenges For Targeting Brown Fat Thermogenesis To Combat Obesity written by Takeshi Yoneshiro and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-28 with Science categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



The Molecular Nutrition Of Fats


The Molecular Nutrition Of Fats
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Author : Vinood B. Patel
language : en
Publisher: Academic Press
Release Date : 2018-10-29

The Molecular Nutrition Of Fats written by Vinood B. Patel and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-29 with Technology & Engineering categories.


The Molecular Nutrition of Fats presents the nutritional and molecular aspects of fats by assessing their dietary components, their structural and metabolic effects on the cell, and their role in health and disease. Subject areas include molecular mechanisms, membranes, polymorphisms, SNPs, genomic wide analysis, genotypes, gene expression, genetic modifications and other aspects. The book is divided into three sections, providing information on the general and introductory aspects, the molecular biology of the cell, and the genetic machinery and its function. Topics discussed include lipid-related molecules, dietary lipids and lipid metabolism, high fat diets, choline, cholesterol, membranes, trans-and saturated fatty acids, and lipid rafts. Other sections provide comprehensive discussions on G protein-coupled receptors, micro RNA, transcriptomics, transcriptional factors, cholesterol, triacylglycerols, beta-oxidation, cholesteryl ester transfer, beta-oxidation, lysosomes, lipid droplets, insulin mTOR signaling and ligands, and more. Summarizes molecular nutrition in health as related to fats Discusses the impact of fats on cancer, heart disease, dementia, and respiratory and intestinal disease Includes preclinical, clinical and population studies Covers the genome, the whole body and whole communities Includes key facts, a mini dictionary of terms and summary points



Stem Cells In Aesthetic Procedures


Stem Cells In Aesthetic Procedures
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Author : Melvin A. Shiffman
language : en
Publisher: Springer
Release Date : 2014-07-21

Stem Cells In Aesthetic Procedures written by Melvin A. Shiffman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-21 with Medical categories.


Interest in the use of stem cells in aesthetic procedures has been increasing rapidly, reflecting the widespread acknowledgment of the tremendous potential of stem cell fat transfer. This is, however, the first book to be devoted entirely to the subject. The book opens by reviewing the history of the development of pluripotent stem cells and the results of research into the biochemistry and physiology of stem cells. Adipose tissue anatomy and survival are discussed and the wide range of aesthetic procedures involving stem cell fat transfer are then described in detail. These procedures relate to the face, breast, buttocks, legs, hands, penis and Poland syndrome. In addition, potential risks and complications are identified. The book has been written by leading experts and will be an invaluable source of information for students, beginners and experienced surgeons in a range of specialties.