The Cerebral Cortex In Neurodegenerative And Neuropsychiatric Disorders
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The Cerebral Cortex In Neurodegenerative And Neuropsychiatric Disorders
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Author : David F. Cechetto
language : en
Publisher: Academic Press
Release Date : 2016-10-14
The Cerebral Cortex In Neurodegenerative And Neuropsychiatric Disorders written by David F. Cechetto and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-14 with Medical categories.
The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders: Experimental Approaches to Clinical Issues focuses on how pre-clinical investigations are addressing the clinical issues surrounding the involvement of the cerebral cortex in selected conditions of the nervous system, including Alzheimer's Disease, Parkinson's, addiction, and cardiovascular dysregulation. Each chapter is written by an expert in his/her field who provides a comprehensive review of the clinical manifestations of cortical involvement and experimental techniques currently available to tackle cortical issues in disease. Thus, this present title provides a link between cortical clinical problems and investigational approaches to help foster future research with high translational value. - Offers a comprehensive overview on the best available in vivo and in vitro models to study cortical involvement - Presents models and specific techniques that help to guide investigators in their choices on how to address research questions experimentally - Provides expert commentary and a perspective on future trends at the end of each chapter - Addresses translational advances and promising therapeutic options - Includes references to key articles for additional detailed study
Dementia
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Author : Bradford Dickerson
language : en
Publisher: Oxford University Press
Release Date : 2014-08-01
Dementia written by Bradford Dickerson and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-01 with Medical categories.
Dementia: Comprehensive Principles and Practice is a clinically-oriented book designed for clinicians, scientists, and other health professionals involved in the diagnosis, management, and investigation of disease states causing dementia. A "who's who" of internationally-recognized experts contribute chapters emphasizing a multidisciplinary approach to understanding dementia. The organization of the book takes an integrative approach by providing three major sections that (1) establish the neuroanatomical and cognitive framework underlying disorders of cognition, (2) provide fundamental as well as cutting-edge material covering specific diseases associated with dementia, and (3) discuss approaches to the diagnosis and treatment of dementing illnesses.
Molecular Aspects Of Neurodegeneration Neuroprotection And Regeneration In Neurological Disorders
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Author : Akhlaq A. Farooqui
language : en
Publisher: Academic Press
Release Date : 2020-09-07
Molecular Aspects Of Neurodegeneration Neuroprotection And Regeneration In Neurological Disorders written by Akhlaq A. Farooqui and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-07 with Medical categories.
Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs. - Provides a comprehensive overview of the molecular aspects of neurodegeneration, neuroprotection, and neuro-regeneration, along with therapeutic strategies for various types of neurological disorders - Provides cutting-edge research information on the signal transduction processes associated with the neurochemistry of neurological disorders - Discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential for treatments of neurological disorders
Neurochemical Aspects Of Neurotraumatic And Neurodegenerative Diseases
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Author : Akhlaq A. Farooqui
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-02
Neurochemical Aspects Of Neurotraumatic And Neurodegenerative Diseases written by Akhlaq A. Farooqui and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-02 with Medical categories.
Collectively, neurodegenerative diseases are characterized by chronic and progressive loss of neurons in discrete areas of the brain, producing debilitating symptoms such as dementia, loss of memory, loss of sensory or motor capability, decreased overall quality of life eventually leading to premature death. Two types of cell death are known to occur during neurodegeneration: (a) apoptosis and (b) necrosis. The necrosis is characterized by the passive cell swelling, intense mitochondrial damage with rapid loss of ATP, alterations in neural membrane permeability, high calcium influx, and disruption of ion homeostasis. This type of cell death leads to membrane lysis and release of intracellular components that induce inflammatory reactions. Necrotic cell death normally occurs at the core of injury site. In contrast, apoptosis is an active process in which caspases (a group of endoproteases with specificity for aspartate residues in protein) are stimulated. Apoptotic cell death is accompanied by cell shrinkage, dynamic membrane blebbing, chromatin condensation, DNA laddering, loss of phospholipids asymmetry, low ATP levels, and mild calcium overload. This type of cell death normally occurs in penumbral region at the ischemic injury site and in different regions in various neurodegenerative diseases.
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Author :
language : en
Publisher: IOS Press
Release Date :
written by and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Behavioral Neurology Neuropsychiatry
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Author : David B. Arciniegas
language : en
Publisher: Cambridge University Press
Release Date : 2013-01-24
Behavioral Neurology Neuropsychiatry written by David B. Arciniegas and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-24 with Medical categories.
The merger of behavioral neurology and neuropsychiatry into a single medical subspecialty, Behavioral Neurology & Neuropsychiatry, requires an understanding of brain-behavior relationships and a clinical approach that transcends the traditional perspectives of neurology and psychiatry. Designed as a primer of concepts and principles, and authored by a multidisciplinary group of internationally known clinical neuroscientists, this book divides into three sections: • Structural and Functional Neuroanatomy (Section I) addresses the neuroanatomy and phenomenology of cognition, emotion, and behavior • Clinical Assessment (Section II) describes neuropsychiatric history taking, neurological and mental status examinations, neuropsychological assessment, and neuroimaging, electrophysiologic, and laboratory methods • Treatment (Section III) discusses environmental, behavioral, rehabilitative, psychological, social, pharmacological, and procedural interventions for cognitive, emotional, and behavioral disorders. By emphasizing the principles of Behavioral Neurology & Neuropsychiatry, this book will improve your understanding of brain-behavior relationships and inform your care of patients and families affected by neurobehavioral disorders.
Imaging Of The Human Brain In Health And Disease
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Author : Philip Seeman
language : en
Publisher: Elsevier
Release Date : 2013-11-15
Imaging Of The Human Brain In Health And Disease written by Philip Seeman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-15 with Science categories.
Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. - A focused introduction to imaging healthy and diseased brains - Focuses on the primary neurotransmitter release - Includes sigma, acetylcholine, opioid, and dopamine receptors - Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease
Smart Diagnostics For Neurodegenerative Disorders
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Author : Arpana Parihar
language : en
Publisher: Elsevier
Release Date : 2023-08-19
Smart Diagnostics For Neurodegenerative Disorders written by Arpana Parihar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-19 with Science categories.
Smart Diagnostics for Neurodegenerative Disorders: Neuro-sensors explores all available biosensor-based approaches and technologies as well as their use in the diagnosis, prognosis and therapeutic management of a variety of neurological disorders such as Alzheimer's, Parkinson's and epileptic disorders. The book also discusses contemporary and revolutionary biosensor platforms that are being used to produce a quantitative quick lab-on-a-chip point-of-care (POC) assay for several types of predictive and diagnostic biomarkers linked with neurodegenerative disorders. It offers a combinatorial strategy for learning recent advances and designing new biosensor-based technologies in the fields of medical science, engineering and biomedical technology. Early detection of neurological conditions has the potential to treat the disease and extend the life expectancy of patients. Recent improvements in biosensor-based approaches that target specific cell surface biomarkers can be used for early detection of neurodegenerative disease. - Provides an in-depth understanding of biomarkers associated with neurodegenerative disease to build and create a variety of biosensors - Presents biosensor-based strategies to create and construct enhanced platforms for quick diagnosis of biomarkers linked to a variety of neurological illnesses - Discusses the current challenges and future trends in developing diagnostic devices for early detection of neurodegenerative disorders, presenting new avenues for more sensitive and selective point-of-care devices
Neuroimaging Of Brain Structure Function Coupling Mechanism In Neuropsychiatric Disorders
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Author : Junghun Cho
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-07
Neuroimaging Of Brain Structure Function Coupling Mechanism In Neuropsychiatric Disorders written by Junghun Cho and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-07 with Science categories.
The Role Of Primary Motor Cortex As A Marker For And Modulator Of Pain Control And Emotional Affective Processing
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Author : Jorge Leite
language : en
Publisher: Frontiers Media SA
Release Date : 2017-09-06
The Role Of Primary Motor Cortex As A Marker For And Modulator Of Pain Control And Emotional Affective Processing written by Jorge Leite and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-06 with categories.
The sensory and motor cortical homunculi proposed by Walter Penfield were a major landmark for the anatomical mapping of the brain. More than 60 years after, the development of new tools to investigate brain function non-invasively has increased our knowledge about the structure and functions of the primary motor Cortex (M1) beyond motor control in both humans and animals. This book highlights the role of the motor cortex that goes way beyond motor functioning. We were interested in both theoretical and empirical contributions related to electrophysiological, pharmacological, neuroimaging, and neuromodulatory studies exploring the role of M1 on non-motor functions, such as pain, abnormal neuroplasticity that may lead to chronic pain conditions; or the relationship between M1 and mental imagery or emotion. This book is comprised of 15 articles published in this edited volume as a research topic collection in Frontiers in Human Neuroscience titled “The Role of Primary Motor Cortex as a Marker and Modulator of Pain Control and Emotional-Affective Processing.”