The Challenge Of Thalidomide


The Challenge Of Thalidomide
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The Challenge Of Thalidomide


The Challenge Of Thalidomide
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Author : Mia Lilly Kellmer Pringle
language : en
Publisher:
Release Date : 1970

The Challenge Of Thalidomide written by Mia Lilly Kellmer Pringle and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with categories.




The Challenge Of Thalidomide


The Challenge Of Thalidomide
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Author : Mia Lilly Kellmer Pringle
language : en
Publisher: Longman Publishing Group
Release Date : 1970

The Challenge Of Thalidomide written by Mia Lilly Kellmer Pringle and has been published by Longman Publishing Group this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Children with disabilities categories.




Dark Remedy


Dark Remedy
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Author : Trent Stephens
language : en
Publisher: Basic Books
Release Date : 2009-04-27

Dark Remedy written by Trent Stephens and has been published by Basic Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-27 with Science categories.


In this riveting medical detective story, Trent Stephens and Rock Brynner recount the history of thalidomide, from the epidemic of birth defects in the 1960's to the present day, as scientists work to create and test an alternative drug that captures thalidomide's curative properties without its cruel side effects. A parable about compassion-and the absence of it-Dark Remedy is a gripping account of thalidomide's extraordinary impact on the lives of individuals and nations over half a century.



Animals And Medicine


Animals And Medicine
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Author : Jack Botting
language : en
Publisher: Open Book Publishers
Release Date : 2015-05-04

Animals And Medicine written by Jack Botting and has been published by Open Book Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-04 with Medical categories.


Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives—both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine—from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.



Global Hiv Aids Medicine


Global Hiv Aids Medicine
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Author : Paul Volberding
language : en
Publisher: Elsevier Health Sciences
Release Date : 2008

Global Hiv Aids Medicine written by Paul Volberding and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.


HIV/AIDS management poses many different challenges around the world, and the therapies available in the West are often not economically feasible in developing countries. This new book is the first to address the myriad of clinical difficulties faced by health practitioners worldwide in managing HIV/AIDS. Edited by the same authorities responsible for the highly respected reference "The Medical Management of AIDS," with Associate Editors that include the President of the International AIDS Society and a preeminent opinion leader in the fight against AIDS in Africa, and authored by a "who's who" of current global experts on HIV and AIDS medicine, this visionary text presents all the practical, indispensable information that clinicians everywhere need to offer their patients the best possible care. Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians. Diagnose AIDS manifestations confidently by comparing them to full-color clinical images. Review essential data quickly through numerous at-a-glance tables.



Suffer The Children


Suffer The Children
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Author :
language : en
Publisher: Viking Adult
Release Date : 1979

Suffer The Children written by and has been published by Viking Adult this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Law categories.


Thalidomide, was hailed as a "wonder drug" that provided a "safe, sound sleep". Thalidomide was a sedative that was found to be effective when given to pregnant women to combat many of the symptoms associated with morning sickness. The drug was tested on animals. When given to pregnant women, thalidomide was a catastrophic drug with tragic side effects. It caused startling birth malformations, and death to babies. Birth defects included: deafness, blindness, disfigurement, cleft palate, and phocomelia (short limbs). The FDA did not approve thalidomide in the United States. Around the world, in the late 1960's and into the early 1970's, the victims of the drug thalidomide and their families entered into class action legal suits against the various drug companies who manufactured and/or distributed the drug. This book tells the story of thalidomide in Great Britain and how the parents overcame the formidable obstacles placed in their way to secure a just settlement for their children.



Silent Shock


Silent Shock
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Author : Michael Magazanik
language : en
Publisher: Text Publishing
Release Date : 2015-05-22

Silent Shock written by Michael Magazanik and has been published by Text Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-22 with Social Science categories.


The baby started to come out. Head first, everything OK. But then I saw that there were no arms. And then no legs. The little girl had only a torso and a head. Lyn Rowe was born in Melbourne in 1962, seven months after her mother Wendy was given a new wonder drug for morning sickness called thalidomide. For fifty years the Rowe family cared for Lyn. Decades of exhausting, round-the-clock work. But then in 2011 Lyn Rowe launched a legal claim against the thalidomide companies. Against the odds, she won a multi-million-dollar settlement. Former journalist Michael Magazanik is one of the lawyers who ran Lyn’s case. In Silent Shock he exposes a fifty-year cover up concerning history’s most notorious drug, and details not only the damning case against manufacturers Grünenthal—whose enthusiastic promotion of their lucrative drug in the face of mounting evidence beggars belief—but also the moving story of the Rowe family. Spanning Australia, the United States, the United Kingdom, Japan, Canada, Sweden and, of course, Germany, Silent Shock is an epic account of corporate wrongdoing against a backdrop of heroic personal struggle and sacrifice. Michael Magazanik has worked as a journalist for the Age, the Australian and ABC-TV, and is now a lawyer with Slater & Gordon. He lives in Melbourne with his partner and three children. ‘Magazanik exposes myths and concealments on a grand scale... A compelling read. Highly recommended.’ BookMooch ‘Magazanik—a lawyer on the Rowes’ legal team and a former journalist—has woven an extraordinary story...Magazanik has moulded [the Rowes'] story into a modern Australian myth, the battlers who took on the pharmaceuticals and won.' Age/Sydney Morning Herald ‘A harrowing read of the damage wrought by this infamous drug.’ WA Today ‘A frightening account of secrets in the pharmaceutical industry and the inspiring story of a family and their legal team that just wouldn't give up.’ Law Society Journal ‘Silent Shock is an ambitious, important book...Magazanik does an excellent job.’ Australian Book Review



Thalidomide Catastrophe


Thalidomide Catastrophe
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Author : Martin Johnson
language : en
Publisher: Onwards and Upwards
Release Date : 2018-05-14

Thalidomide Catastrophe written by Martin Johnson and has been published by Onwards and Upwards this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-14 with Law categories.


"e;This momentous book is the first comprehensive history of thalidomide...It demonstrates how many thousands of victims could have been spared very late in the day if Chemie Grunenthal had taken any notice of the early alarms: ... [It] carries conviction by its scientific rigour, and the clarity of the writing. Fifty years after the deaths and sufferings, the thalidomide tragedy is marked by ... the odour of corruption and cover up."e; - Sir Harold Evans, former editor of The Sunday Times and The Times



Drug Repurposing And Repositioning


Drug Repurposing And Repositioning
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2014-08-08

Drug Repurposing And Repositioning written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-08 with Medical categories.


Drug development can be time-consuming and expensive. Recent estimates suggest that, on average, it takes 10 years and at least $1 billion to bring a drug to market. Given the time and expense of developing drugs de novo, pharmaceutical companies have become increasingly interested in finding new uses for existing drugs - a process referred to as drug repurposing or repositioning. Historically, drug repurposing has been largely an unintentional, serendipitous process that took place when a drug was found to have an offtarget effect or a previously unrecognized on-target effect that could be used for identifying a new indication. Perhaps the most recognizable example of such a successful repositioning effort is sildenafil. Originally developed as an anti-hypertensive, sildenafil, marketed as Viagra and under other trade names, has been repurposed for the treatment of erectile dysfunction and pulmonary arterial hypertension. Viagra generated more than $2 billion worldwide in 2012 and has recently been studied for the treatment of heart failure. Given the widespread interest in drug repurposing, the Roundtable on Translating Genomic-Based Research for Health of the Institute of Medicine hosted a workshop on June 24, 2013, in Washington, DC, to assess the current landscape of drug repurposing activities in industry, academia, and government. Stakeholders, including government officials, pharmaceutical company representatives, academic researchers, regulators, funders, and patients, were invited to present their perspectives and to participate in workshop discussions. Drug Repurposing and Repositioning is the summary of that workshop. This report examines enabling tools and technology for drug repurposing; evaluates the business models and economic incentives for pursuing a repurposing approach; and discusses how genomic and genetic research could be positioned to better enable a drug repurposing paradigm.



Casarett And Doull S Toxicology


Casarett And Doull S Toxicology
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Author : Louis J. Casarett
language : en
Publisher: McGraw-Hill Professional Publishing
Release Date : 1999

Casarett And Doull S Toxicology written by Louis J. Casarett and has been published by McGraw-Hill Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Poisoning categories.


This newest addition to the Companion Handbook Series is perfect for the toxicologist or pharmacy student who requires a brief introduction to the fundamental principles of toxicology but does not have immediate access to the textbook, nor the time for consultation. Fully page referenced to the classic text in the field, concepts are organized and presented in a logical progression from general principles to specific topics such as organ system toxicology, specific agent toxicology, and environmental toxicology. Where possible the information is summarized in tables or presented in outline format.