The Challenge Of Tuberculosis In The 21st Century


The Challenge Of Tuberculosis In The 21st Century
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The Challenge Of Tuberculosis In The 21st Century


The Challenge Of Tuberculosis In The 21st Century
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Author : Alberto L. García-Basteiro
language : en
Publisher: European Respiratory Society
Release Date : 2023-09-01

The Challenge Of Tuberculosis In The 21st Century written by Alberto L. García-Basteiro and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-01 with Medical categories.


Recent years have witnessed key developments in the diagnosis and treatment of tuberculosis. Alongside this, and running in direct opposition to this progress, was the COVID-19 pandemic, which had an unprecedented detrimental effect on tuberculosis control and the achievement of targets set by the End TB Strategy. This timely and important Monograph provides a crucial update on recent changes, developments and setbacks in the field, and calls for a re-commitment to the achievement of the End TB Strategy and Sustainable Development Goals. Written by authors from across the world, the Monograph covers: diagnosis; advances in treatment; prevention; and tuberculosis control challenges in different populations and contexts.



The Challenge Of Tuberculosis In The 21st Century


The Challenge Of Tuberculosis In The 21st Century
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Author : Alberto L. García-Basteiro
language : en
Publisher:
Release Date : 2023

The Challenge Of Tuberculosis In The 21st Century written by Alberto L. García-Basteiro and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with categories.




Disease Control Priorities Third Edition Volume 6


Disease Control Priorities Third Edition Volume 6
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Author : King K. Holmes
language : en
Publisher: World Bank Publications
Release Date : 2017-11-06

Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-06 with Medical categories.


Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.



Discovering Tuberculosis


Discovering Tuberculosis
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Author : Christian W. McMillen
language : en
Publisher: Yale University Press
Release Date : 2015-06-28

Discovering Tuberculosis written by Christian W. McMillen and has been published by Yale University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-28 with History categories.


Tuberculosis is one of the world’s deadliest infectious diseases, killing nearly two million people every year—more now than at any other time in history. While the developed world has nearly forgotten about TB, it continues to wreak havoc across much of the globe. In this interdisciplinary study of global efforts to control TB, Christian McMillen examines the disease’s remarkable staying power by offering a probing look at key locations, developments, ideas, and medical successes and failures since 1900. He explores TB and race in east Africa, in South Africa, and on Native American reservations in the first half of the twentieth century, investigates the unsuccessful search for a vaccine, uncovers the origins of drug-resistant tuberculosis in Kenya and elsewhere in the decades following World War II, and details the tragic story of the resurgence of TB in the era of HIV/AIDS. Discovering Tuberculosis explains why controlling TB has been, and continues to be, so difficult.



Systematic Screening For Active Tuberculosis


Systematic Screening For Active Tuberculosis
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2013

Systematic Screening For Active Tuberculosis written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.


There have been calls to revisit the experiences of TB screening campaigns that were widely applied in Europe and North America in the mid-20th century, as well as more recent experiences with TB screening in countries with a high burden of the disease, and to assess their possible relevance for TB care and prevention in the 21st century. In response, WHO has developed guidelines on screening for active TB. An extensive review of the evidence has been undertaken. The review suggests that screening, if done in the right way and targeting the right people, may reduce suffering and death, but the review also highlights several reasons to be cautious. As discussed in detail in this book, there is a need to balance potential benefits against the risks and costs of screening; this conclusion is mirrored by the history of TB screening. This publication presents the first comprehensive assessment by WHO of the appropriateness of screening for active TB since the recommendations made in 1974 by the Expert Committee. However, the relative effectiveness and cost effectiveness of screening remain uncertain, a point that is underscored by the systematic reviews presented in this guideline. Evidence suggests that some risk groups should always be screened, whereas the prioritization of other risk groups as well as the choice of screening approach depend on the epidemiology, the health-system context, and the resources available. This book sets out basic principles for prioritizing risk groups and choosing a screening approach; it also emphasizes the importance of assessing the epidemiological situation, adapting approaches to local situations, integrating TB screening into other health-promotion activities, minimizing the risk of harm to individuals, and engaging in continual monitoring and evaluation. It calls for more and better research to assess the impact of screening and to develop and evaluate new screening tests and approaches.



Ending Neglect


Ending Neglect
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2000-08-31

Ending Neglect written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-08-31 with Medical categories.


Tuberculosis emerged as an epidemic in the 1600s, began to decline as sanitation improved in the 19th century, and retreated further when effective therapy was developed in the 1950s. TB was virtually forgotten until a recent resurgence in the U.S. and around the worldâ€"ominously, in forms resistant to commonly used medicines. What must the nation do to eliminate TB? The distinguished committee from the Institute of Medicine offers recommendations in the key areas of epidemiology and prevention, diagnosis and treatment, funding and organization of public initiatives, and the U.S. role worldwide. The panel also focuses on how to mobilize policy makers and the public to effective action. The book provides important background on the pathology of tuberculosis, its history and status in the U.S., and the public and private response. The committee explains how the U.S. can act with both self-interest and humanitarianism in addressing the worldwide incidence of TB.



Disease Control Priorities In Developing Countries


Disease Control Priorities In Developing Countries
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Author : Dean T. Jamison
language : en
Publisher: World Bank Publications
Release Date : 2006-04-02

Disease Control Priorities In Developing Countries written by Dean T. Jamison and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-02 with Medical categories.


Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.



Disease And Mortality In Sub Saharan Africa


Disease And Mortality In Sub Saharan Africa
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Author : Dean T. Jamison
language : en
Publisher: World Bank Publications
Release Date : 2006-01-01

Disease And Mortality In Sub Saharan Africa written by Dean T. Jamison and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-01 with Medical categories.


Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.



The Plague And I


The Plague And I
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Author : Betty MacDonald
language : en
Publisher: HarperCollins
Release Date : 2016-11-01

The Plague And I written by Betty MacDonald and has been published by HarperCollins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-01 with Biography & Autobiography categories.


“Getting tuberculosis in the middle of your life is like starting downtown to do a lot of urgent errands and being hit by a bus. When you regain consciousness you remember nothing about the urgent errands. You can’t even remember where you were going.” Thus begins Betty MacDonald’s memoir of her year in a sanatorium just outside Seattle battling the “White Plague.” MacDonald uses her offbeat humor to make the most of her time in the TB sanatorium—making all of us laugh in the process.



Tuberculosis And Multidrug Resistant Tuberculosis


Tuberculosis And Multidrug Resistant Tuberculosis
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Author : Suhail Ahmad
language : en
Publisher: Nova Science Pub Incorporated
Release Date : 2013-01-01

Tuberculosis And Multidrug Resistant Tuberculosis written by Suhail Ahmad and has been published by Nova Science Pub Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-01 with Health & Fitness categories.


Tuberculosis (TB), causing nine million active disease cases and 1.5 million deaths every year, is a formidable public health challenge, particularly in poor and developing countries around the world. Major reasons for global burden of TB include association of active disease with human immunodeficiency virus (HIV) coinfection or other underlying immunosuppressive conditions such as diabetes and increasing incidence of drug-resistant, multidrug-resistant (MDR) (resistant at least to rifampicin and isoniazid) and extensively drug-resistant (XDR) (additionally resistant to a fluoroquinolone plus kanamycin/amikacin/capreomycin) strains of M. tuberculosis. While treatment of drug-susceptible TB is effective in >95 percent of disease cases, supervised therapy for >6 months is challenging. Inadequate/inappropriate therapy due to inability of poor patients to pay for drugs and non-adherence to treatment (regimen and duration) often results in much lower cure rates and evolution of drug-resistant strains of M. tuberculosis due to mutations occurring at a predictable rate in genes encoding drug targets. Sequential accumulation of mutations results in evolution of MDR and XDR strains of M. tuberculosis. Today, drug-resistant TB and MDR-TB have become prevalent in many parts of the world and XDR-TB strains are emerging rapidly. While MDR-TB is difficult to treat, XDR-TB is untreatable in most developing countries.