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The Chemokines


The Chemokines
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The Chemokines


The Chemokines
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Author : I.J.D. Lindley
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Chemokines written by I.J.D. Lindley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The first symposium in this series was held at the Royal College of Surgeons of England in December 1988 and was entitled "Novel Neutrophil Stimulating Peptides". That symposium successfully brought together the majority of laboratories working in the area of interleukin-8 and related peptides; see Immunology Today 10: 146-147 (1989). The Second International Symposium on Chemotactic Cytokines was held at the same venue in June 1990, and a much-increased attendance reflected the accelerating pace of work in the area of these chemotactic cytokines. The proceedings of that meeting were published in Advances in Experimental Medicine and Biology, vol. 305 (1991). The rapid advances made in the field of chemotactic cytokines over the last 18 months necessitated a third Symposium in this series to collate and place in perspective an explosion of new data. The Third International Symposium on Chemotactic Cytokines was held between August 31 and September 1, 1992 in Baden-bei-Wien, Austria. However, the lack of a clear nomenclature system was creating some confusion in the area, especially as new factors continue to be discovered and classified as family members. In the past, these inflammatory mediators had been placed arbitrarily under the broad heading of "intercrines" or "chemotactic cytokines" with no clear classification guidelines to follow. This nomenclature issue was addressed at the Symposium, where investigators in the field were invited to reach a consensus regarding a collective name for these mediators. The resulting decision was to identify the major family as chemokines, to replace all previous terms.



The Chemokines


The Chemokines
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Author : Ivan J. D. Lindley
language : en
Publisher:
Release Date : 1992

The Chemokines written by Ivan J. D. Lindley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Chemotactic factors categories.




The Chemokine Factsbook


The Chemokine Factsbook
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Author : Krishna Vaddi
language : en
Publisher: Elsevier
Release Date : 1997-04-01

The Chemokine Factsbook written by Krishna Vaddi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-04-01 with Medical categories.


How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalog of the essential properties of families of molecules. Gene organization, amino acid sequences, physicochemical properties, and biological activity are presented using a common, easy-to-follow format. Taken together they compile everything you want to know about proteins but are too busy to look for. The Chemokine FactsBook contains more than 40 entries on chemokines, and chemokine receptors from human or other origin, including IL-8, MCP-1, C5-a, RANTES, Lymphotactin, and CC CKR-1. The text provides information on tissue sources, target cells, physicochemical properties, transcription factors, regulation of expression in disease, receptor-binding characteristics, gene structure and location, amino acid sequences, and accession numbers and references. Contains over 40 entries on chemokines and chemokine receptors from human or other origin, including: IL-8 MCP-1 C5-a RANTES Lymphotactin CC CKR-1 Entries provide information on: Tissue sources Target cells Physicochemical properties Transcription factors Regulation of expression Expression in disease Receptor-binding characteristics Gene structure and location Amino acid sequences Database accession numbers References



The Chemokine Receptors


The Chemokine Receptors
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Author : Jeffrey K. Harrison
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-17

The Chemokine Receptors written by Jeffrey K. Harrison and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-17 with Medical categories.


This volume, new to The Receptors series, focuses on several areas, including the birth, maturation, and structure of Chemokines; Neutrophil, Dendritic, and Lymphocyte trafficking; and Chemokine Receptors in diseases such as AIDs and lung cancer. In particular the book contains cutting-edge information ranging from basic molecular and cellular mechanisms to physiological and pathological roles of chemokines.



Chemokine Protocols


Chemokine Protocols
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Author : Amanda E.I. Proudfoot
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05

Chemokine Protocols written by Amanda E.I. Proudfoot and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Medical categories.


The chemokines family of small proteins are involved in numerous b- logical processes ranging from hematopoiesis, angiogenesis, and basal l- kocyte trafficking to the extravasation and tissue infiltration of leukocytes in response to inflammatory agents, tissue damage, and bacterial or viral infection. Chemokines exert their effects through a family of seven G-protein coupled transmembrane receptors. Worldwide interest in the chemokine field surged dramatically early in 1996, with the finding that certain chemokine receptors were the elusive coreceptors, required along with CD4, for HIV infection. Today, though over 40 human chemokines have been described, the n- ber of chemokine receptors lags behind—only 17 human chemokine receptors have been identified so far. What has emerged over the years is that most chemokine receptors bind several distinct ligands, and indeed the majority of chemokines are able to bind to multiple chemokine receptors, explaining to some extent the apparent disparity in the numbers of chemokines and rec- tors. Yet in spite of the apparent redundancy in chemokine/chemokine rec- tor interactions, it is clear that in vivo, spatial, temporal, and indeed cell- and tissue-specific expression of both chemokines and their receptors are imp- tant factors in determining the precise nature of cellular infiltrates in phy- ological and pathological processes.



The Chemokine System In Experimental And Clinical Hematology


The Chemokine System In Experimental And Clinical Hematology
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Author : Oystein Bruserud
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-30

The Chemokine System In Experimental And Clinical Hematology written by Oystein Bruserud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-30 with Medical categories.


The aim of the issue is to describe and explain the importance of the chemokine system in hematology. The chemokine system is probably important for many aspects of normal as well as malignant hematopoiesis. A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation. The present reviews illustrate that chemokines can be involved in leukemogenesis. The chemokine system is also important both for the crosstalk between malignant cells and their neighbouring nonmalignant stromal cells (including endothelial cells) as well as for immunoregulation in patients treated with allogeneic stem cell transplantation. Thus, chemokines are important both for the pathogenesis and treatment of hematological diseases.



Tumor Microenvironment


Tumor Microenvironment
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Author : Alexander Birbrair
language : en
Publisher: Springer Nature
Release Date : 2020-02-14

Tumor Microenvironment written by Alexander Birbrair and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-14 with Science categories.


Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment. Each chapter focuses on the chemokines patterns of expression, their regulation, and their roles in immune cell recruitment, as well as how they affect cancer immunity and tumorigenesis. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Chemokines – Part A updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking a comprehensive update on research in the tumor microenvironment.



Chemokines In Disease


Chemokines In Disease
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Author : Caroline A. Hébert
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-06-01

Chemokines In Disease written by Caroline A. Hébert and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-06-01 with Medical categories.


Caroline Hébert and a panel of key experimentalists and clinical investigators comprehensively review the state-of-the-art in the chemokine field, ranging from the effects of chemokines and their receptors in retroviral infections, to their role in inflammation, angiogenesis/angiostasis, and tumor cell biology. The book examines in detail fifteen recently identified chemokines and elucidates the role of chemokine function in vivo from animal experiments. Animal models are also used to explore how chemokines operate in a variety of chronic and acute inflammatory diseases and in noninflammatory processes. A detailed review of the emerging role of chemokines in viral biology is also presented, with emphasis on HIV biology and novel therapeutic possibilities. Chemokines in Disease: Biology and Clinical Research summarizes the rapidly expanding knowledge of a dazzling array of chemokines and provides fresh insights into the development of powerful new drugs for treating a wide spectrum of diseases.



The Chemokines In Disease


The Chemokines In Disease
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Author : I. J. D. Lindley
language : en
Publisher:
Release Date : 1993

The Chemokines In Disease written by I. J. D. Lindley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with categories.




Tumor Microenvironment


Tumor Microenvironment
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Author : Alexander Birbrair
language : en
Publisher: Springer Nature
Release Date : 2021-07-21

Tumor Microenvironment written by Alexander Birbrair and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-21 with Medical categories.


Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment. Each chapter focuses on the chemokines patterns of expression, their regulation, and their roles in immune cell recruitment, as well as how they affect cancer immunity and tumorigenesis.Taken alongside its companion volumes, Tumor Microenvironment: The Role of Chemokines – Part B updates us on what we know about various aspects of the tumor microenvironment, as well as apprises us on future directions in the field. This book is essential reading for advanced cell biology and cancer biology students as well as scientists seeking an update on recent developments and research in the tumor microenvironment.