The Control Of Human Retrovirus Gene Expression
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The Control Of Human Retrovirus Gene Expression
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Author : B. Robert Franza
language : en
Publisher: CSHL Press
Release Date : 1988
The Control Of Human Retrovirus Gene Expression written by B. Robert Franza and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Health & Fitness categories.
Transacting Functions Of Human Retroviruses
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Author : Irvin S.Y. Chen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Transacting Functions Of Human Retroviruses written by Irvin S.Y. Chen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes. The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
Genetic Structure And Regulation Of Hiv
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Author : William A. Haseltine
language : en
Publisher: Raven Press (ID)
Release Date : 1991
Genetic Structure And Regulation Of Hiv written by William A. Haseltine and has been published by Raven Press (ID) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
Based on a conference sponsored by the Harvard AIDS Institute, this volume examines the control of gene expression of the human immunodeficiency virus type 1 (HIV-1), the human T cell leukemia virus types 1 and 2 (HTLV-1 and 2) and related retroviruses.
Human Retroviruses
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Author : Bryan Cullen
language : en
Publisher: Oxford University Press
Release Date : 1993
Human Retroviruses written by Bryan Cullen and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Gene Expression Regulation. categories.
The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Retroviruses
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Author : Ronald Swanstrom
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Retroviruses written by Ronald Swanstrom and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This book gives a synthesis of current knowledge on ret- rovirology. Each chapter deals with a different step in the virus life cycle, detailing the molecular aspects of virus replication. The comparison of different retroviruses exemplifies variations. Specific topics include the evolution of retrovirus genomes, integration of the provirus, viral DNA transcriptional and translational control of viral gene expression, processing of viral proteins, and packaging of virion RNA. Data on HIV and HTLV-1 are covered as well as research on animal retrovirus sys- tems.
Recent Advances In Human Retroviruses Principles Of Replication And Pathogenesis
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Author :
language : en
Publisher:
Release Date :
Recent Advances In Human Retroviruses Principles Of Replication And Pathogenesis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Human Retrovirus Protocols
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Author : Tuofu Zhu
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
Human Retrovirus Protocols written by Tuofu Zhu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Science categories.
A cutting-edge collection of basic and state-of-the-art methods optimized for investigating the molecular biology of this class of retrovirus. These readily reproducible techniques range from methods for the isolation and detection of human retroviruses to cutting-edge methods for exploring the interplay between the viruses and the host. Here, the researcher will find up-to-date techniques for the isolation and propagation of HIV, HTLV, and foamy virus from a variety of sources. There are also assays for determining the cell tropism of HIV-1, the coreceptor usage of HIV-1, and human gene expression with HIV-1 infection by microarrays, as well as for phenotyping HIV-1 infected monocytes and examining their fitness. Highlights include the detection and quantification of HIV-1 in resting CD4+, a new cloning system for making recombinent virus, cDNA microarrays, and the determination of genetic polymorphisms in two recently identified HIV-1 co-factors that are critical for HIV-1 infection.
Human Retroviral Infections
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Author : Kenneth E. Ugen
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
Human Retroviral Infections written by Kenneth E. Ugen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.
The discovery of the human T cell leukemia virus type I in the late 1970s heralded a new era in retrovirology. For the first time, it was demonstrated that a retrovirus could play a role in the development of a human disease, in this case adult T cell leukemia (ATL). Several years later, the acquired immunodeficiency syndrome (AIDS) epidemic began, and it was dem- strated that a retrovirus, originally designated the human T cell lymp- tropic virus type 3, was the causal agent of this syndrome. This virus, later named the human immunodeficiency virus type 1 (HIV-1), has since been extensively studied in terms of its pathogenesis as well as its ability to elicit immune responses. In that time, a tremendous amount of information has been obtained about the virus. Although recent drug regimens have been useful in significantly lowering viral loads and perhaps maintaining an asymptomatic state among individuals infected with HIV-1, an established “cure” for AIDS eludes us. In addition, the effective drug therapies are very expensive, and are not available to infected people in the third world, where greater than 90% of new infections occur. Furthermore, the development of viral resistance against the drug therapies is an additional concern. Despite extensive study, no effective vaccine has been developed. One of the problems in developing an effective vaccine against HIV-1 is the ability of the virus, particularly in the immunogenic envelop glycoprotein, to undergo amino acid hypervariability.
Genetic Structure And Regulation Of Hiv
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Author : William A. Haseltine
language : en
Publisher:
Release Date : 1991-01-01
Genetic Structure And Regulation Of Hiv written by William A. Haseltine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-01-01 with categories.
Gene Expression And Regulation In Mammalian Cells Transcription Toward The Establishment Of Novel Therapeutics
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Author : Fumiaki Uchiumi
language : en
Publisher:
Release Date : 2018
Gene Expression And Regulation In Mammalian Cells Transcription Toward The Establishment Of Novel Therapeutics written by Fumiaki Uchiumi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Genetics categories.
Sixty years after the ""central dogma,"" great achievements have been developed in molecular biology. We have also learned the important functions of noncoding RNAs and epigenetic regulations. More importantly, whole genome sequencing and transcriptome analyses enabled us to diagnose specific diseases. This book is not only intended for students and researchers working in laboratory but also physicians and pharmacists. This volume consists of 14 chapters, divided into 4 parts. Each chapter is written by experts investigating biological stresses, epigenetic regulation, and functions of transcription factors in human diseases. All articles presented in this volume by excellent investigators provide new insights into the studies in transcriptional control in mammalian cells and will inspire us to develop or establish novel therapeutics against human diseases.