The Essential Guide To N Of 1 Trials In Health


The Essential Guide To N Of 1 Trials In Health
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The Essential Guide To N Of 1 Trials In Health


The Essential Guide To N Of 1 Trials In Health
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Author : Jane Nikles
language : en
Publisher: Springer
Release Date : 2015-10-05

The Essential Guide To N Of 1 Trials In Health written by Jane Nikles and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-05 with Medical categories.


N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials. Written and edited by some of the world’s leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.



The Essential Guide To N Of 1 Trials In Health


The Essential Guide To N Of 1 Trials In Health
DOWNLOAD eBooks

Author : Jane Nikles
language : en
Publisher:
Release Date : 2015

The Essential Guide To N Of 1 Trials In Health written by Jane Nikles and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.


N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials. Written and edited by some of the world's leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.



Single Case Experimental Designs For Clinical Research And Neurorehabilitation Settings


Single Case Experimental Designs For Clinical Research And Neurorehabilitation Settings
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Author : Robyn Tate
language : en
Publisher: Routledge
Release Date : 2019-01-15

Single Case Experimental Designs For Clinical Research And Neurorehabilitation Settings written by Robyn Tate and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-15 with Psychology categories.


This book is a practical resource designed for clinicians, researchers, and advanced students who wish to learn about single-case research designs. It covers the theoretical and methodological underpinnings of single-case designs, as well as their practical application in the clinical and research neurorehabilitation setting. The book briefly traces the history of single-case experimental designs (SCEDs); outlines important considerations in understanding and planning a scientifically rigorous single-case study, including internal and external validity; describes prototypical single-case designs (withdrawal-reversal designs and the medical N-of-1 trial, multiple-baseline designs, alternating-treatments designs, and changing-criterion designs) and required features to meet evidence standards, threats to internal validity, and strategies to address them; addresses data evaluation, covering visual analysis of graphed data, statistical techniques, and clinical significance; and provides a practical ten-step procedure for implementing single-case methods. Each chapter includes detailed illustrative examples from the neurorehabilitation literature. Novel features include: A focus on the neurorehabilitation setting, which is particularly suitable for single-case designs because of the complex and often unique presentation of many patients/clients. A practical approach to the planning, implementation, data analysis, and reporting of single-case designs. An appendix providing a detailed summary of many recently published SCEDs in representative domains in the neurorehabilitation field, covering basic and instrumental activities of daily living, challenging behaviours, disorders of communication and cognition, mood and emotional functions, and motor-sensory disabilities. It is valuable reading for clinicians and researchers in several disciplines working in rehabilitation, including clinical and neuropsychology, education, language and speech pathology, occupational therapy, and physical therapy. It is also an essential resource for advanced students in these fields who need a textbook for specialised courses on research methodology and use of single-case design in applied clinical and research settings.



Grieve S Modern Musculoskeletal Physiotherapy


Grieve S Modern Musculoskeletal Physiotherapy
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Author : Deborah Falla
language : en
Publisher: Elsevier Health Sciences
Release Date : 2024-04-02

Grieve S Modern Musculoskeletal Physiotherapy written by Deborah Falla and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-02 with Medical categories.


Originally edited by Gregory Grieve, a founder of modern manual therapy, the fifth edition of Grieve's Modern Musculoskeletal Physiotherapy continues to offer contemporary evidence, models of diagnosis and practice that make this one of the most highly respected reference books for physiotherapists. This edition has been fully updated to provide an overview of the latest science in a rapidly evolving field. It includes detailed directions for research-informed patient care for a range of musculoskeletal disorders, as well as up-to-date information on the global burden, research methodologies, measurements, and principles of assessment and management. A new international editorial board, with experience in both research and clinical practice, bring a truly comprehensive perspective to this book, meaning those practising musculoskeletal physiotherapy today will find it highly clinically relevant to their work. Edited by an internationally recognised editorial board – brings expertise in both research and clinical practice Fully updated with the latest published evidence Clear guidance on evidence-based contemporary practice Management of conditions relating to both the vertebral column and peripheral joints Updated reviews on the science and practice of a wide range of treatment modalities Principles of effective communication, screening, clinical reasoning, lifestyle considerations, behavioural change and self-management Summary boxes and clinical tips to support clinical assessment and management More than 300 figures and illustrations Global burden of musculoskeletal disorders – including history, epidemiology and new models of care A range of new research methodologies, including N of 1 research designs, systematic reviews and meta-analyses, population-based cohort studies, consensus research and response analyses in musculoskeletal research How to navigate the endless wave of information and assess different levels of evidence New measures New chapter on cost analyses and value-based care Digital rehabilitation methods



The Palgrave Handbook Of Paralympic Studies


The Palgrave Handbook Of Paralympic Studies
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Author : Ian Brittain
language : en
Publisher: Springer
Release Date : 2018-02-15

The Palgrave Handbook Of Paralympic Studies written by Ian Brittain and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-15 with Sports & Recreation categories.


This handbook provides a critical assessment of contemporary issues that define the contours of the Paralympic Movement generally and the Paralympic Games more specifically. It addresses conceptualisations of disability sport, explores the structure of the Paralympic Movement and considers key political strategic and governance issues which have shaped its development. The Palgrave Handbook of Paralympic Studies is written by a range of international authors, a number of whom are senior strategists as well as academics, and explores legacy themes through case studies of recent Paralympic games. Written in the wake of the 2016 Rio Paralympic Games, it provides an assessment of contemporary challenges faced by the International Paralympic Committee and other key stakeholders in the Paralympic Movement. Its critical assessment of approaches to branding, classification, social inclusion and technological advances makes this handbook a valuable resource for undergraduate study across a range of sport and disability related programmes, as well as a point of reference for researchers and policy makers.



Precision Personalized Pediatric Oncology And Immune Therapies Rather Customize Than Randomize


Precision Personalized Pediatric Oncology And Immune Therapies Rather Customize Than Randomize
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Author : Irene Slavc
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-04

Precision Personalized Pediatric Oncology And Immune Therapies Rather Customize Than Randomize written by Irene Slavc and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-04 with categories.




The Sage Encyclopedia Of Research Design


The Sage Encyclopedia Of Research Design
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Author : Bruce B. Frey
language : en
Publisher: SAGE Publications
Release Date : 2022-01-27

The Sage Encyclopedia Of Research Design written by Bruce B. Frey and has been published by SAGE Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-27 with Social Science categories.


The SAGE Encyclopedia of Research Design maps out how one makes decisions about research design, interprets data, and draws valid inferences, undertakes research projects in an ethical manner, and evaluates experimental design strategies and results. From A-to-Z, this four-volume work covers the spectrum of research design strategies and topics including, among other things: fundamental research design principles, ethics in the research process, quantitative versus qualitative and mixed-method designs, completely randomized designs, multiple comparison tests, diagnosing agreement between data and models, fundamental assumptions in analysis of variance, factorial treatment designs, complete and incomplete block designs, Latin square and related designs, hierarchical designs, response surface designs, split-plot designs, repeated measures designs, crossover designs, analysis of covariance, statistical software packages, and much more. Research design, with its statistical underpinnings, can be especially daunting for students and novice researchers. At its heart, research design might be described simply as a formalized approach toward problem solving, thinking, and acquiring knowledge, the success of which depends upon clearly defined objectives and appropriate choice of statistical design and analysis to meet those objectives. The SAGE Encyclopedia of Research Design will assist students and researchers with their work while providing vital information on research strategies.



Practical Data Analytics For Innovation In Medicine


Practical Data Analytics For Innovation In Medicine
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Author : Gary D. Miner
language : en
Publisher: Academic Press
Release Date : 2023-02-08

Practical Data Analytics For Innovation In Medicine written by Gary D. Miner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-08 with Computers categories.


Practical Data Analytics for Innovation in Medicine: Building Real Predictive and Prescriptive Models in Personalized Healthcare and Medical Research Using AI, ML, and Related Technologies, Second Edition discusses the needs of healthcare and medicine in the 21st century, explaining how data analytics play an important and revolutionary role. With healthcare effectiveness and economics facing growing challenges, there is a rapidly emerging movement to fortify medical treatment and administration by tapping the predictive power of big data, such as predictive analytics, which can bolster patient care, reduce costs, and deliver greater efficiencies across a wide range of operational functions. Sections bring a historical perspective, highlight the importance of using predictive analytics to help solve health crisis such as the COVID-19 pandemic, provide access to practical step-by-step tutorials and case studies online, and use exercises based on real-world examples of successful predictive and prescriptive tools and systems. The final part of the book focuses on specific technical operations related to quality, cost-effective medical and nursing care delivery and administration brought by practical predictive analytics. Brings a historical perspective in medical care to discuss both the current status of health care delivery worldwide and the importance of using modern predictive analytics to help solve the health care crisis Provides online tutorials on several predictive analytics systems to help readers apply their knowledge on today’s medical issues and basic research Teaches how to develop effective predictive analytic research and to create decisioning/prescriptive analytic systems to make medical decisions quicker and more accurate



Pivotal Trials In Ophthalmology


Pivotal Trials In Ophthalmology
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Author : Jenny C. Dohlman
language : en
Publisher: Springer Nature
Release Date : 2021-02-11

Pivotal Trials In Ophthalmology written by Jenny C. Dohlman and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-11 with Medical categories.


Pivotal Trials in Ophthalmology: A Guide for Trainees is an introductory text designed to give trainees a comprehensive and accessible overview of landmark trials in the different subspecialties of ophthalmology, and may also serve as a useful reference for practicing ophthalmologists, optometrists and researchers in the field. The text is subdivided by subspecialty, with each chapter authored by both a trainee and an expert in the field. A selection of pivotal research studies that have shaped how practitioners diagnose, manage, and treat disease are reviewed in chronological order. The purpose, study design, results, and study limitations are reviewed, and the key takeaway points from each study are listed in a digestible, bullet-point format. By listing the studies in chronological order, the reader will have an understanding of how studies have built upon each other and how knowledge has evolved over time. This text can serve as a basic introductory text for first year ophthalmology residents around which a standardized curriculum can be shaped, a study guide for board examination study, or a reference text for practitioners and researchers at any stage of training and practice.



Handbook Of Intellectual Disabilities


Handbook Of Intellectual Disabilities
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Author : Johnny L. Matson
language : en
Publisher: Springer Nature
Release Date : 2019-09-03

Handbook Of Intellectual Disabilities written by Johnny L. Matson and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-03 with Psychology categories.


This handbook offers a comprehensive review of intellectual disabilities (ID). It examines historical perspectives and foundational principles in the field. The handbook addresses philosophy of care for individuals with ID, as well as parent and professional issues and organizations, staffing, and working on multidisciplinary teams. Chapters explore issues of client protection, risk factors of ID, basic research issues, and legal concerns. In addition, chapters include information on evidence-based assessments and innovative treatments to address a variety of behaviors associated with ID. The handbook provides an in-depth analysis of comorbid physical disorders, such as cerebral palsy, epilepsy and seizures, and developmental coordination disorders (DCD), in relation to ID. Topics featured in this handbook include: Informed consent and the enablement of persons with ID. The responsible use of restraint and seclusion as a protective measure. Vocational training and job preparation programs that assist individuals with ID. Psychological and educational approaches to the treatment of aggression and tantrums. Emerging technologies that support learning for students with ID. Key sexuality and relationship issues that are faced by individuals with ID. Effective approaches to weight management for individuals with intellectual and developmental disabilities. The Handbook of Intellectual Disabilities is an essential reference for researchers, graduate students, clinicians and related therapists and professionals in clinical child and school psychology, pediatrics, social work, developmental psychology, behavioral therapy/rehabilitation, child and adolescent psychiatry, and special education.