The Exercise Induced Expression Of Heat Shock Proteins In Human Skeletal Muscle
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The Exercise Induced Expression Of Heat Shock Proteins In Human Skeletal Muscle
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Author : James P. Morton
language : en
Publisher:
Release Date : 2006
The Exercise Induced Expression Of Heat Shock Proteins In Human Skeletal Muscle written by James P. Morton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
Heat Shock Proteins And Whole Body Physiology
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Author : Alexzander A. A. Asea
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-10
Heat Shock Proteins And Whole Body Physiology written by Alexzander A. A. Asea and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-10 with Medical categories.
Heat Shock Proteins and Whole Body Physiology is an exciting new book in the Heat Shock Proteins series which provides the most up-to-date review on novel mechanisms insights into the important role played by heat shock proteins in human physiology. Written by leaders in the field of heat shock protein exercise physiology, neuroscience and aging, the chapters systematically and in a step wise fashion takes the reader through the fascinating mechanisms by which heat shock proteins modulate human disease and pathophysiology and provides answers as to its biological significance to the host. Section I, introduces the readers to the role played by heat shock proteins in various diseases and disorders (Heat Shock Proteins and Disease). Section II, addresses the role heat shock proteins play in psychological disorders including post traumatic stress disorders and learning (Heat Shock Proteins and Psychological Stress). Section III, present a detailed review of the role played by heat shock proteins in exercise physiology (Heat Shock Proteins and Exercise Physiology). This book is a must read for heat shock protein researchers, graduate and postgraduate fellows in the field of Medicine in general and specialities in Excersie Physiology, Neuroscience, Immunology, Aging and Pathology.
The Expression Of Heat Shock Protein In Human Skeletal Muscle Effects Of Muscle Fibre Phenotype And Training Background
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Author :
language : en
Publisher:
Release Date : 2013
The Expression Of Heat Shock Protein In Human Skeletal Muscle Effects Of Muscle Fibre Phenotype And Training Background written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
The Role Of Heat Shock Protein 70 In Protecting Muscle Mechanical Function Serca Function In Human Skeletal Muscle
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Author : Riley David Stewart
language : en
Publisher:
Release Date : 2009
The Role Of Heat Shock Protein 70 In Protecting Muscle Mechanical Function Serca Function In Human Skeletal Muscle written by Riley David Stewart and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Two studies were conducted to determine if Hsp70 is able to protect human skeletal muscle from muscle mechanical damage and alterations in SERCA activity associated with prolonged concentric exercise.
Effects Of Acute Exercise On Heat Shock Protein 72 Expression And Delayed Onset Muscle Soreness In Skeletal Muscle Of Young And Older Men
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Author :
language : en
Publisher:
Release Date : 1999
Effects Of Acute Exercise On Heat Shock Protein 72 Expression And Delayed Onset Muscle Soreness In Skeletal Muscle Of Young And Older Men written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
Effect Of Aerobic Exercise And The Induced Increase In Heat Shock Proteins On Recovery Of Skeletal Muscle Function After Ischemia Reperfusion Injury
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Author : Edward Kelly Merritt
language : en
Publisher:
Release Date : 2004
Effect Of Aerobic Exercise And The Induced Increase In Heat Shock Proteins On Recovery Of Skeletal Muscle Function After Ischemia Reperfusion Injury written by Edward Kelly Merritt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
The purpose of this study was to determine the effect of exercise training on the recovery of skeletal muscle function following ischemia reperfusion injury. Three groups of animals underwent 6 weeks of aerobic training to increase heat shock protein content of skeletal muscle. After training, 2 groups were subjected to a 2-hour ischemic bout induced by pneumatic tourniquet (TK). In one group 7 days following TK application in vivo force was measured in a method similar to Ashton-Miller (1992). Another group recovered 14 days before in vivo force was measured. Force of the TK leg vs. contralateral leg measured 7 and 14 days following TK application was 29.6 +/- 2.3% and 55.0 +/- 3.3% respectively. Non-exercised control rat’s TK leg force production was 22.0 +/- 2.9% and 53.1 +/-5.2% when compared to the contralateral leg. These data suggest that exercise training prior to I/R allows for greater maximal force production 7 days following TK application
Heat Shock Stress Protein Changes In Human Skeletal Muscle Following High Force Eccentric Exercise
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Author : Heather Sue Thompson
language : en
Publisher:
Release Date : 1994
Heat Shock Stress Protein Changes In Human Skeletal Muscle Following High Force Eccentric Exercise written by Heather Sue Thompson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Exercise categories.
Effects Of Concentric And Eccentric Muscle Contractions On Il 6 Signaling In Human Skeletal Muscle And Downstream Regulation Of Hsp 72 Gene Expression
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Author : Travis Harvey
language : en
Publisher:
Release Date : 2008
Effects Of Concentric And Eccentric Muscle Contractions On Il 6 Signaling In Human Skeletal Muscle And Downstream Regulation Of Hsp 72 Gene Expression written by Travis Harvey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Cellular signal transduction categories.
Purpose: To determine the effects of concentric and eccentric muscle contractions on IL-6 signaling and its possible downstream regulation of HSP-72 expression in human skeletal muscle, and whether contraction-induced IL-6 expression may initiate a cytoprotective mechanism in the muscle by activating HSP-72 and HSP-27. Methods: Using a cross-over design, 10 recreationally active males (20.60 " 2.80 yrs; 77.35 " 12.79 kg) participated in 2 separate bouts of 10 sets of 10 unilateral isokinetic knee extensions at 30°/sec. Each subject performed one concentric (CON) and one eccentric (ECC) bout, with strength assessed 5 days prior to and at 24 and 48 hr after the bout. Muscle soreness and blood samples were sampled immediately before exercise (PRE), immediately post-exercise (POST), and at 2, 6, 24, and 48 hr after exercise for serum levels of CK, IL-6, IL-1[beta], and TNF-[alpha]. Muscle biopsies were obtained at PRE, POST, and at 2 and 6 hr post-exercise and assessed for protein levels of IL-6, HSP-72, HSP-27, NF-kB, p38 MAPK, STAT-1, and STAT-3 and for mRNA expression of IL-6, HSP-72, and HSP-27. Repeated measures MANOVA for isokinetic peak torque revealed a significant decrease in strength at 24 and 48 hr post-exercise. Repeated measures MANOVA on muscle soreness and CK located a significant (p [less-than or equal to]] 0.05) main effect for time for both variables, but not for contraction type. Repeated measures MANOVA for cytokine serum variables demonstrated no significant results. Repeated measures MANOVA for muscle variables demonstrated no significant main effect for contraction, though a significant main effect for time was located. Pairwise comparisons demonstrated a significant difference from immediately post-exercise to 6 hr post-exercise for HSP-27. Gene expression of muscle variables demonstrated no significant results. Conclusion: The CON and ECC bouts demonstrated muscle damage through significant elevations in CK and muscle fatigue through significantly decreased torque production at 24 and 48 hr post-exercise. However, the damage induced during the acute bouts appears to have been insufficient to produce systemic and intramuscular signaling of the IL-6 pathway and its associated factors. Further human research still needs to be conducted on this pathway with the factors investigated here, though other exercise intensities and modes should be considered.
Skeletal Muscle Structure Function And Plasticity
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Author : Richard L. Lieber
language : en
Publisher: LWW
Release Date : 2010
Skeletal Muscle Structure Function And Plasticity written by Richard L. Lieber and has been published by LWW this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Health & Fitness categories.
In its Third Edition, this text addresses basic and applied physiological properties of skeletal muscle in the context of the physiological effects from clinical treatment. Anyone interested in human movement analysis and the understanding of generation and control from the musculoskeletal and neuromuscular systems in implementing movement will find this a valuable resource. A highlight color has been added to this edition's updated figures and tables, and the color plates section has been doubled, ensuring that all figures that need color treatment to clarify concepts receive this treatment. A new Clinical Problem feature uses concepts presented in each chapter in the context of a specific clinical case--for example, a spinal cord injury, a sports accident, or rehabilitation after bed rest.
The Chaperonopathies
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Author : Alberto J.L. Macario
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-10
The Chaperonopathies written by Alberto J.L. Macario and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-10 with Medical categories.
This Brief provides a concise review of chaperonopathies, i.e., diseases in which molecular chaperones play an etiologic-pathogenic role. Introductory chapters deal with the chaperoning system and chaperoning teams and networks, HSP-chaperone subpopulations, the locations and functions of chaperones, and chaperone genes in humans. Other chapters present the chaperonopathies in general, including their molecular features and mechanistic classification into by defect, excess, or mistake. Subsequent chapters discuss the chaperonopathies in more detail, focusing on their distinctive characteristics: primary or secondary; quantitative and/or qualitative; structural and hereditary or acquired; genetic polymorphisms; gene dysregulation; age-related; associated with cancer, chronic inflammatory conditions, and autoimmune diseases. The interconnections between the chaperoning and the immune systems in cancer development, chronic inflammation, autoimmunity, and ageing are outlined, which leads to a discussion on the future prospects of chaperonotherapy. The latter may consist of chaperone gene and protein replacement/supplementation in cases of deficiency and of gene or protein blocking when the chaperone actively promotes disease. The last chapter presents the extracellular chaperones and details on how the chaperone Hsp60 is secreted into the extracellular space and, thus, appears in the blood of cancer patients with potential to participate in carcinogenesis and chronic inflammation and autoimmunity. Chaperones as clinically useful biomarkers are mentioned when pertinent. Likewise, guidelines for clinical evaluation of chaperonopathies and for their histopathological and molecular identification are provided throughout. The book also provides extensive bibliography organized by chapter and topic with comments.