The Genetics Of Male Infertility
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The Genetics Of Male Infertility
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Author : Douglas T. Carrell
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-08
The Genetics Of Male Infertility written by Douglas T. Carrell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-08 with Medical categories.
In this book, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments. New tools discussed are discussed. This book therefore serves as a guide to evidence-based clinical applications, and a preview of future possibilities.
Genetics Of Male Infertility
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Author : Mohamed Arafa
language : en
Publisher: Springer Nature
Release Date : 2020-03-14
Genetics Of Male Infertility written by Mohamed Arafa and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-14 with Health & Fitness categories.
This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagnosis and treatment of infertile men with genetic abnormalities. Moreover, it provides essential algorithms that may aid in counseling patients in the clinic. The text is arranged in four thematic sections for easy reference. The genetic foundation of male reproduction is presented in part 1, including regulation of sperm production, the structure of sperm chromatin, and spermatogenesis. The impact of genetic abnormalities on male infertility is the subject of part 2, covering sperm defects, mitochondrial function and DNA fragmentation. The clinical case material in part 3 illustrates real-world examples of genetic etiologies and the current diagnostic and therapeutic strategies for conditions such as vas asplasia, cryptorchidism, immotile cilia syndrome, sperm aneuploidy and other challenging scenarios. Casting forward, the fourth and final section presents an overview of future possibilities for management of genetic causes of male infertility, including gene editing. Fully exploring the clinical context of these genetic conditions in a practical manner that appeals to the practicing clinician, Genetics of Male Infertility is an exciting and essential text for reproductive medicine specialists, andrologists, urologists, researchers and all other clinicians treating infertile patients.
Genetics Of Male Infertility
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Author : Mohamed Arafa
language : en
Publisher:
Release Date : 2020
Genetics Of Male Infertility written by Mohamed Arafa and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Andrology categories.
This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagnosis and treatment of infertile men with genetic abnormalities. Moreover, it provides essential algorithms that may aid in counseling patients in the clinic. The text is arranged in four thematic sections for easy reference. The genetic foundation of male reproduction is presented in part 1, including regulation of sperm production, the structure of sperm chromatin, and spermatogenesis. The impact of genetic abnormalities on male infertility is the subject of part 2, covering sperm defects, mitochondrial function and DNA fragmentation. The clinical case material in part 3 illustrates real-world examples of genetic etiologies and the current diagnostic and therapeutic strategies for conditions such as vas asplasia, cryptorchidism, immotile cilia syndrome, sperm aneuploidy and other challenging scenarios. Casting forward, the fourth and final section presents an overview of future possibilities for management of genetic causes of male infertility, including gene editing. Fully exploring the clinical context of these genetic conditions in a practical manner that appeals to the practicing clinician, Genetics of Male Infertility is an exciting and essential text for reproductive medicine specialists, andrologists, urologists, researchers and all other clinicians treating infertile patients. .
The Genetic Basis Of Male Infertility
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Author : Ken McElreavey
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-03
The Genetic Basis Of Male Infertility written by Ken McElreavey and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-03 with Medical categories.
Every year there are new and exciting developments in assisted human reproduction, but how much do we really know about the underlying causes of infertility? This volume explores recent progress in the understanding of the genetics of spermatogenesis and male infertility. Topics include fundamental advances and current problems in the development and function of the testis, an outline of clinical findings in male infertility and an overview of the role of the Y chromosome in male fertility. Comprehensive critiques of posttranscriptional control during spermatogenesis, mammalian meiotic sterility, and comparative genetics of human spermatogenesis from the perspective of yeast, Drosophila and mice provide a global overview of the field.
Genetics Of Male Infertility
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Author :
language : en
Publisher:
Release Date : 2007
Genetics Of Male Infertility written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Genetics Of Human Infertility
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Author : P.H. Vogt
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2017-09-12
Genetics Of Human Infertility written by P.H. Vogt and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-12 with Medical categories.
Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.
Male Infertility Understanding Causes And Treatment
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Author : RAJENDER SINGH
language : en
Publisher: Springer
Release Date : 2017-06-17
Male Infertility Understanding Causes And Treatment written by RAJENDER SINGH and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-17 with Medical categories.
This book covers the latest research on male infertility. The topics discussed range from understanding the genetic basis of infertility, to its causes and treatment. Since infertility is also of great interest to the general public, the book also includes a detailed description of what infertility is and how one can understand the different types. Given the complex etiology of infertility, the book includes a number of chapters defining the known and probable causes of male infertility. Providing detailed information suitable for patients and clinicians alike, it also features a separate section on treatment, the ultimate goal.
Male Fertility And Infertility
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Author : T. D. Glover
language : en
Publisher: Cambridge University Press
Release Date : 2009-03-19
Male Fertility And Infertility written by T. D. Glover and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-19 with Medical categories.
This contemporary account of male fertility provides a much needed bridge between those seeking to understand the subject from an evolutionary and biological perspective and those with clinical responsibility for the investigation and treatment of infertility. Accordingly, the first half of the book deals with the evolutionary aspects of male reproduction and sperm competition, sperm production and delivery in man and other animals, spermatogenesis and epididymal function, sperm transport in the female tract and the apparent decline in human sperm count. The second part of the book puts greater emphasis on clinical problems and opens with a discussion of intracytoplasmic sperm injection, its value and limitations. This is followed by a review of modern developments in the genetics of male fertility and proceeds to a further chapter on the role of surgical procedures used in the treatment. Semen analysis is critically reviewed and the molecular techniques now being used in preimplantation diagnosis and in the study of mitochondrial inheritance are fully described. Taken together these chapters, written by an international team of authors, illustrate the breadth of vision needed to tackle the problem of male fertility.
Genetic Damage In Human Spermatozoa
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Author : Elisabetta Baldi
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-08-16
Genetic Damage In Human Spermatozoa written by Elisabetta Baldi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-16 with Medical categories.
There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.
The Infertility Trap
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Author : R. John Aitken
language : en
Publisher: Cambridge University Press
Release Date : 2022-05-05
The Infertility Trap written by R. John Aitken and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-05 with Medical categories.
Human fertility rates are dropping at an unprecedented rate. This book highlights the consequences of our current inaction.