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The Genome Generation


The Genome Generation
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The Genome Generation


The Genome Generation
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Author : Elizabeth Finkel
language : en
Publisher: Melbourne Univ. Publishing
Release Date : 2012

The Genome Generation written by Elizabeth Finkel and has been published by Melbourne Univ. Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Science categories.


The year 2001 marked more than just the beginning of Stanley Kubrick's Space Odyssey, it marked the beginning of the genome era. That was the year scientists first read the 3 billion letters of DNA that make up the human genome. This was followed by a veritable Noah's Ark of genomesandmdash;sponges and worms, dogs and cows, rice and wheat, chimps and elephantsandmdash;180 creatures aboard so far. So what have we learned from all this? How has it changed the way we practise medicine, grow crops and breed livestock? What have we learned about evolution? These are the questions science writer and molecular biologist Elizabeth Finkel asked herself four years ago. To find the answers she travelled the science frontier from Botswana to Boston, from Warracknabeal to Mexico and tracked down scientists working in the field. Their stories, told here, paint the picture of what it means to be part of the genome generation. 'The Genome Generation is absolutely riveting. These tales from the frontier are a 'must read' for everyone who wishes to understand our pastandmdash;the logic of evolutionandmdash;or take a peep into our exciting future at the creation of 'super plants' through 'digital agriculture'.'andmdash;R.A. Mashelkar, CSIR Bhatnagar Fellow and India President, Global Research Alliance



The Genome Generation


The Genome Generation
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Author : Steven Monroe Lipkin
language : en
Publisher:
Release Date : 2016

The Genome Generation written by Steven Monroe Lipkin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.


"A leading geneticist explores what promises to be one of the most transformative advances in health and medicine in history. Almost every week, another exciting headline appears about new advances in the field of genetics. Genetic testing is experiencing the exponential growth once seen with the Internet, and the plummeting cost of DNA sequencing makes it increasingly accessible for individuals and families. Dr. Steven M. Lipkin suggests that today's genomics is like the last century's nuclear physics: a powerful tool for good if used correctly, but potentially dangerous in the wrong hands. DNA testing is promising in treating serious disease, but Beijing Genomics, one of the world's largest genomics centers, is quietly developing gene tests to predict intelligence and athletic prowess in prenatal embryo selection. DNA testing could also lead to unnecessary procedures and significantly higher health-care costs. And all too often, sequencing errors diagnose patients with debilitating and fatal genetic diseases.The Genome Generation immerses readers in stories of real patients on the genomics frontier and explores the transformative potential and dangerous risks of genetic technology. It will inform anxious parents increasingly bombarded by offers of costly new prenatal testing products, and demonstrate how genetic technology, when deployed properly, can prevent or treat genetic disorders such as neurological diseases or cancer. Lipkin explains the science in depth, but in terms a layperson can follow"--Provided by publisher.



Welcome To The Genome


Welcome To The Genome
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Author : Robert DeSalle
language : en
Publisher: John Wiley & Sons
Release Date : 2020-01-27

Welcome To The Genome written by Robert DeSalle and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-27 with Science categories.


The popular introduction to the genomic revolution for non-scientists—the revised and updated new edition Welcome to the Genome is an accessible, up-to-date introduction to genomics—the interdisciplinary field of biology focused on the structure, function, evolution, mapping, and editing of an organism's complete set of DNA. Written for non-experts, this user-friendly book explains how genomes are sequenced and explores the discoveries and challenges of this revolutionary technology. Genomics is a mixture of many fields, including not only biology, engineering, computer science, and mathematics, but also social sciences and humanities. This unique guide addresses both the science of genomics and the ethical, moral, and social questions that rise from the technology. There have been many exciting developments in genomics since this book's first publication. Accordingly, the second edition of Welcome to the Genome offers substantial new and updated content to reflect recent major advances in genome-level sequencing and analysis, and demonstrates the vast increase in biological knowledge over the past decade. New sections cover next-generation technologies such as Illumina and PacBio sequencing, while expanded chapters discuss controversial ethical and philosophical issues raised by genomic technology, such as direct-to-consumer genetic testing. An essential resource for understanding the still-evolving genomic revolution, this book: Introduces non-scientists to basic molecular principles and illustrates how they are shaping the genomic revolution in medicine, biology, and conservation biology Explores a wide range of topics within the field such as genetic diversity, genome structure, genetic cloning, forensic genetics, and more Includes full-color illustrations and topical examples Presents material in an accessible, user-friendly style, requiring no expertise in genomics Discusses past discoveries, current research, and future possibilities in the field Sponsored by the American Museum of Natural History, Welcome to the Genome: A User's Guide to the Genetic Past, Present, and Future is a must-read book for anyone interested in the scientific foundation for understanding the development and evolutionary heritage of all life.



Genetic Transparency Ethical And Social Implications Of Next Generation Human Genomics And Genetic Medicine


Genetic Transparency Ethical And Social Implications Of Next Generation Human Genomics And Genetic Medicine
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Author : Malte Dreyer
language : en
Publisher: BRILL
Release Date : 2016-01-12

Genetic Transparency Ethical And Social Implications Of Next Generation Human Genomics And Genetic Medicine written by Malte Dreyer and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-12 with Social Science categories.


Genetic Transparency? tackles the question of who has, or should have access to personal genomic information. Genomic science is revolutionary in how it changes the way we live, individually and together, and how it changes the shape of society. If this is so, then – the authors of this volume claim – the rules that regulate genetic transparency should be debated carefully, openly and critically. It is important to see that the social and cultural meanings of DNA and genetic sequences are much richer than can be accounted for by purely biomedical knowledge. In this book, an international group of leading genomics experts and scholars from the humanities and social sciences discuss how the new accessibility of genomic information affects interpersonal relationships, our self-understandings, ethics, law, and healthcare systems. Contributors are: Kirsten Brukamp, Gabrielle Christenhusz, Lorraine Cowley, Malte Dreyer, Jeanette Erdmann, Andrei Famenka, Teresa Finlay, Caroline Fündling, Shannon Gibson, Cathy Herbrand, Angeliki Kerasidou, Lene Koch, Fruzsina Molnár-Gábor, Tim Ohnhäuser, Christoph Rehmann-Sutter, Benedikt Reiz, Vasilja Rolfes, Sara Tocchetti



Next Generation Systematics


Next Generation Systematics
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Author : Peter D. Olson
language : en
Publisher: Cambridge University Press
Release Date : 2016-06-16

Next Generation Systematics written by Peter D. Olson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-16 with Science categories.


Cheap and plentiful genome sequence data is transforming biology, and will surely transform systematics. This volume explores how.



Next Generation Sequencing And Sequence Data Analysis


Next Generation Sequencing And Sequence Data Analysis
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Author : Kuo Ping Chiu
language : en
Publisher: Bentham Science Publishers
Release Date : 2015-11-04

Next Generation Sequencing And Sequence Data Analysis written by Kuo Ping Chiu and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-04 with Science categories.


Nucleic acid sequencing techniques have enabled researchers to determine the exact order of base pairs - and by extension, the information present - in the genome of living organisms. Consequently, our understanding of this information and its link to genetic expression at molecular and cellular levels has lead to rapid advances in biology, genetics, biotechnology and medicine. Next-Generation Sequencing and Sequence Data Analysis is a brief primer on DNA sequencing techniques and methods used to analyze sequence data. Readers will learn about recent concepts and methods in genomics such as sequence library preparation, cluster generation for PCR technologies, PED sequencing, genome assembly, exome sequencing, transcriptomics and more. This book serves as a textbook for students undertaking courses in bioinformatics and laboratory methods in applied biology. General readers interested in learning about DNA sequencing techniques may also benefit from the simple format of information presented in the book.



Next Generation Genome Sequencing


Next Generation Genome Sequencing
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Author : Michal Janitz
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-24

Next Generation Genome Sequencing written by Michal Janitz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-24 with Science categories.


Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug discovery and health care. As such, it presents a detailed comparative analysis of commercially available platforms as well as insights into alternative, emerging sequencing techniques. In addition, the book not only covers the principles of DNA sequencing techniques but also social, ethical and commercial aspects, the concept of personalized medicine and a five-year perspective of DNA sequencing.



Next Generation Sequencing


Next Generation Sequencing
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Author : Jerzy Kulski
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-01-14

Next Generation Sequencing written by Jerzy Kulski and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-14 with Medical categories.


Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.



Next Generation Sequencing Data Analysis


Next Generation Sequencing Data Analysis
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Author : Xinkun Wang
language : en
Publisher: CRC Press
Release Date : 2016-04-06

Next Generation Sequencing Data Analysis written by Xinkun Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-06 with Mathematics categories.


A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi



Next Generation Sequencing Technologies And Challenges In Sequence Assembly


Next Generation Sequencing Technologies And Challenges In Sequence Assembly
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Author : Sara El-Metwally
language : en
Publisher: Springer Science & Business
Release Date : 2014-04-19

Next Generation Sequencing Technologies And Challenges In Sequence Assembly written by Sara El-Metwally and has been published by Springer Science & Business this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-19 with Science categories.


The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.