The Hayflick Limit
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The Hayflick Limit
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Author : Matthew Tierney
language : en
Publisher: Coach House Books
Release Date : 2005-04-14
The Hayflick Limit written by Matthew Tierney and has been published by Coach House Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-14 with Poetry categories.
Shifting focus from the limits of the telescope to the limits of the microscope, the poems in Matthew Tierneys second collection place a premium on inventiveness while embracing extremes of fear, pain, cognition and time. With demotic verve and a humming line, he gives voice to a range of characters who scrape out meaning in a carnivalesque universe that has birthed black holes and Warner Bros. cartoons, murky market economies, murkier quantum laws, Vincent Price, Molotov cocktails, seedless grapes, Area 51 and competing Theories of Everything.To be human is to cope with knowing. In the early 60s, Leonard Hayflick determined that healthy cells can divide only a finite number of times. Known as the Hayflick Limit, it sets an unsurpassable lifespan for our species at just over 120 years. The ultimate of limits, tackled by poetry of humour, intelligence and lucidity.The Hayflick Limit concerns itself with the boundaries of the cosmic and subatomic how the mind contains both and the sadsack creatures in the nexus, human beings. What does it mean to be an intelligent species? What does it mean to be an intelligent person?
Cellular Ageing And Replicative Senescence
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Author : Suresh I.S. Rattan
language : en
Publisher: Springer
Release Date : 2016-05-09
Cellular Ageing And Replicative Senescence written by Suresh I.S. Rattan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-09 with Medical categories.
This book covers the origins and subsequent history of research results in which attempts have been made to clarify issues related to cellular ageing, senescence, and age-related pathologies including cancer. Cellular Ageing and Replicative Senescence revisits more than fifty-five years of research based on the discovery that cultured normal cells are mortal and the interpretation that this phenomenon is associated with the origins of ageing. The mortality of normal cells and the immortality of cancer cells were also reported to have in vivo counterparts. Thus began the field of cytogerontology. Cellular Ageing and Replicative Senescence is organized into five sections: history and origins; serial passaging and progressive ageing; cell cycle arrest and senescence; system modulation; and recapitulation and future expectations. These issues are discussed by leading thinkers and researchers in biogerontology and cytogerontology. This collection of articles provides state-of-the-art information, and will encourage students, teachers, health care professionals and others interested in the biology of ageing to explore the fascinating and challenging question of why and how our cells age, and what can and cannot be done about it.
How And Why We Age
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Author : Leonard Hayflick
language : en
Publisher:
Release Date : 1996
How And Why We Age written by Leonard Hayflick and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Aging categories.
"How long can humans live? Is immortality possible? Just what is the aging process? The aging and inevitable death of the human body have inspired more myths and outrageous quackery than anything else subject to scientific inquiry. . . . Now comes a most fascinating book, insightful and scholarly, to provide what answers have emerged so far." --San Francisco Chronicle Here, at last, preeminent cell biologist Leonard Hayflick presents the truth about human aging. Based on more than thirty years of pioneering research in the field, How and Why We Age explores not only how our major biological systems change as we grow older, but also examines the intangible alterations in our modes of thinking and feeling, our moods and sexual desires, our personality traits and our memories. With the immediacy of the latest scientific discoveries, Dr. Hayflick explains how aging affects every part of the body, and dispels many of the most persistent aging myths, to show that: * Hearts do not naturally get weaker with age. * Regular exercise and a low-fat diet won't slow aging. * Curing cancer would only add two years to the average sixty-five-year-old American life. Curing heart disease, however would add fourteen years. * Only five percent of people over the age of sixty-five are in nursing homes * No human has lived--or probably can live--past 120 years. Gracefully written, clearly organized, and packed with essential facts and statistics, How and Why We Age is a landmark study of the aging process for readers of all ages. "Written in clear, nontechnical language, it is an excellent introduction to the scientific and demographic literature on this multifacetedsubject." --Nature
The Vaccine Race
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Author : Meredith Wadman
language : en
Publisher: Penguin
Release Date : 2017-02-07
The Vaccine Race written by Meredith Wadman and has been published by Penguin this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-07 with Science categories.
"A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman’s smooth prose calmly spins a surpassingly complicated story into a real tour de force."—The New York Times “Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—Nature The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus--measles--on the rise today, no medical story could have more human drama, impact, or urgency than The Vaccine Race.
Intrinsic Mutagenesis
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Author : Burnet MacFarlane
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Intrinsic Mutagenesis written by Burnet MacFarlane and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This book is something which almost accidentally has developed very differently from how it was initially planned. The intention was to elaborate the part played by the immune system in ageing with the role of the thymus as central theme. It was to be essentially an expansion of a lecture I gave in 1970 and would inevitably have been concerned with much the same material as Walford's book, The Immunologic Theory of Aging, though from a different slant. What changed its character arose from a series of attempts to find logical connection between two findings that most gerontologists regard as axiomatic: that the lifespan of a mammal is genetically determined, and that the actual process of ageing is an accumulation of genetic error, of somatic mutations. It is possible that the connection is so indirect, circuitous and multiform that generations of detailed and unattractive research will be needed to elucidate it, or, more likely, the whole matter discarded as a non-problem. But a more inspiring approach does seem possible. The working hypothesis, which halfway through its writing became the new central theme of the book, arose when I was a member of a committee appointed by the Australian Academy of Science at the request of the Australian Government to advise on the danger from French nuclear tests in the South Pacific.
The Immortal Life Of Henrietta Lacks
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Author : Rebecca Skloot
language : en
Publisher: Pan Macmillan
Release Date : 2019-03-07
The Immortal Life Of Henrietta Lacks written by Rebecca Skloot and has been published by Pan Macmillan this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-07 with Biography & Autobiography categories.
A heartbreaking account of a medical miracle: how one woman’s cells – taken without her knowledge – have saved countless lives. The Immortal Life of Henrietta Lacks is a true story of race, class, injustice and exploitation. ‘No dead woman has done more for the living . . . A fascinating, harrowing, necessary book.’ – Hilary Mantel, Guardian With an introduction Sarah Moss, author of by author of Summerwater. Her name was Henrietta Lacks, but scientists know her as HeLa. Born a poor black tobacco farmer, her cancer cells – taken without asking her – became a multimillion-dollar industry and one of the most important tools in medicine. Yet Henrietta’s family did not learn of her ‘immortality’ until more than twenty years after her death, with devastating consequences . . . Rebecca Skloot’s moving account is the story of the life, and afterlife, of one woman who changed the medical world forever. Balancing the beauty and drama of scientific discovery with dark questions about who owns the stuff our bodies are made of, The Immortal Life of Henrietta Lacks is an extraordinary journey in search of the soul and story of a real woman, whose cells live on today in all four corners of the world. Now an HBO film starring Oprah Winfrey and Rose Byrne.
Encyclopedia Of Aging And Public Health
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Author : Sana Loue
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-01-16
Encyclopedia Of Aging And Public Health written by Sana Loue and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-16 with Medical categories.
Americans are living longer, and the elder population is growing larger. To meet the ongoing need for quality information on elder health, the Encyclopedia of Aging and Public Health combines multiple perspectives to offer readers a more accurate and complete picture of the aging process. The book takes a biopsychosocial approach to the complexities of its subject. In-depth introductory chapters include coverage on a historical and demographic overview of aging in America, a guide to biological changes accompanying aging, an analysis of the diversity of the U.S. elder population, legal issues commonly affecting older adults, and the ethics of using cognitively impaired elders in research. From there, over 425 entries cover the gamut of topics, trends, diseases, and phenomena: -Specific populations, including ethnic minorities, custodial grandparents, and centenarians -Core medical conditions associated with aging, from cardiac and pulmonary diseases to Parkinson’s and Alzheimer’s -Mental and emotional disorders -Drugs/vitamins/alternative medicine -Disorders of the eyes, feet, and skin -Insomnia and sleep disorders; malnutrition and eating disorders -Sexual and gender-related concerns -And a broad array of social and political issues, including access to care, abuse/neglect, veterans’ affairs, and assisted suicide Entries on not-quite-elders’ concerns (e.g., midlife crisis, menopause) are featured as well. And all chapters and entries include references and resource lists. The Encyclopedia has been developed for maximum utility to clinicians, social workers, researchers, and public health professionals working with older adults. Its multidisciplinary coverage and scope of topics make this volume an invaluable reference for academic and public libraries.
The Hayflick Limit
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Author : Matthew Tierney
language : en
Publisher: Coach House Books
Release Date : 2005-04-14
The Hayflick Limit written by Matthew Tierney and has been published by Coach House Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-14 with Poetry categories.
To be human is to cope with knowing. In the early 1960s, Leonard Hayflick determined that healthy cells can divide only a finite number of times. Known as the Hayflick Limit, it sets an unsurpassable lifespan for our species at just over 120 years. Shifting focus between the limits of the microscope and the limits of the telescope, Matthew Tierney gives voice to a range of characters who scrape out meaning in a carnivalesque universe, one that has birthed black holes and Warner Bros. cartoons, murky market economies, murkier quantum laws, Vincent Price, Molotov cocktails, seedless grapes, Area 51 and competing Theories of Everything.
The Evolution Of Senescence In The Tree Of Life
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Author : Richard P. Shefferson
language : en
Publisher: Cambridge University Press
Release Date : 2017-02-23
The Evolution Of Senescence In The Tree Of Life written by Richard P. Shefferson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-23 with Science categories.
Top researchers in the field introduce interdisciplinary perspectives on senescence, presenting new insights and cutting-edge research.
Boon And Bane Of Not Being Subject To The Hayflick Limit
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Author : Miriam Herbert
language : en
Publisher: GRIN Verlag
Release Date : 2015-01-23
Boon And Bane Of Not Being Subject To The Hayflick Limit written by Miriam Herbert and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-23 with Science categories.
Pre-University Paper from the year 2014 in the subject Biology - Cytology, grade: 15 Punkte = 1,0, , language: English, abstract: All living things have to die. This fundamental truth is held to apply even to the smallest unit of life – cells. However, there is a phenomenon that is sometimes called biological immortality. It refers to cells that live beyond their proclaimed life span, which is roughly set by the Hayflick limit. All cancer cells have acquired this property; they divide indefinitely, which is the essential problem with cancer cells. On the other hand, researchers are very much interested in the molecular mechanism behind this property to may be able to use it to extend life and rejuvenate cells. Cells that are not subject to the Hayflick limit are generally seen as a threat to the human body, however, they are interesting subjects of experiments and scientists have already learned a great deal of knowledge by studying these mutants and continue to gain more important insights into the functioning of any kind of human body cell. Immortal cells can be boon and bane for humankind. Certain aspects of this issue will be discussed.