The Human Genome
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The Human Genome Project
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Author : Thomas F. Lee
language : en
Publisher: Springer
Release Date : 2013-12-11
The Human Genome Project written by Thomas F. Lee and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-11 with Medical categories.
Describes the ten-year, multimillion dollar Human Genome Project and its process of gene mapping; includes concerns of critics of the project.
The Human Genome
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Author : Paul F. Kisak
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2016-04-27
The Human Genome written by Paul F. Kisak and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-27 with categories.
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and spermgamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNAbase pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution. There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been determined. The total length of the human genome is over 3 billion base pairs. The genome is organized into 22 paired chromosomes, plus the X chromosome (one in males, two in females) and, in males only, one Y chromosome. These are all large linear DNA molecules contained within the cell nucleus. The genome also includes the mitochondrial DNA, a comparatively small circular molecule present in each mitochondrion. Basic information about these molecules and their gene content, based on a reference genome that does not represent the sequence of any specific individual, are provided in the following table. This book is an excellent overview of the human genome, the genetics involved and DNA.
Mapping And Sequencing The Human Genome
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1988-01-01
Mapping And Sequencing The Human Genome written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-01-01 with Science categories.
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
The Human Genome
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Author : T. Strachan
language : en
Publisher: Taylor & Francis
Release Date : 1992
The Human Genome written by T. Strachan and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Science categories.
A concise description of the structure of the human genome and the ways in which recent knowledge is influencing medical research and practice. If you have any interest in the Human Genome Project, this book is a must!
Drawing The Map Of Life
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Author : Viktor K. McElheny
language : en
Publisher: Basic Books
Release Date : 2012-07-31
Drawing The Map Of Life written by Viktor K. McElheny and has been published by Basic Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-31 with Science categories.
Drawing the Map of Life is the dramatic story of the Human Genome Project from its origins, through the race to order the 3 billion subunits of DNA, to the surprises emerging as scientists seek to exploit the molecule of heredity. It's the first account to deal in depth with the intellectual roots of the project, the motivations that drove it, and the hype that often masked genuine triumphs. Distinguished science journalist Victor McElheny offers vivid, insightful profiles of key people, such as David Botstein, Eric Lander, Francis Collins, James Watson, Michael Hunkapiller, and Craig Venter. McElheny also shows that the Human Genome Project is a striking example of how new techniques (such as restriction enzymes and sequencing methods) often arrive first, shaping the questions scientists then ask. Drawing on years of original interviews and reporting in the inner circles of biological science, Drawing the Map of Life is the definitive, up-to-date story of today's greatest scientific quest. No one who wishes to understand genome mapping and how it is transforming our lives can afford to miss this book.
Perilous Knowledge
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Author : Tom Wilkie
language : en
Publisher: Univ of California Press
Release Date : 1993-01-01
Perilous Knowledge written by Tom Wilkie and has been published by Univ of California Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-01-01 with Science categories.
The Human Genome Project has been called a scientific "search for the Holy Grail" or the genetics equivalent of the moon race. Thousands of researchers worldwide are analyzing the details of human DNA, hoping to identify all of the tens of thousands of human genes that are the blueprint for the human body. Physicist and writer Tom Wilkie offers a lively, compelling history of this scientifically fascinating and politically contentious undertaking. Beginning with the discovery of DNA by James Watson and Francis Crick in 1953, Wilkie's narrative unfolds with the intrigue of a detective story. He reviews in nontechnical terms the many step-by-step developments from different scientific teams that finally made it seem as if it would be possible to sequence the human genome. He goes on to consider the potential social consequences, good and bad, of learning to manipulate the human genetic code. What will happen as we try to prevent and cure disease or attempt to "improve" ourselves and our children by genetic means? A most readable introduction to the science of genetics and the potential consequences of the Human Genome Project, Perilous Knowledge provides background for the startling headlines that quite possibly signal changes to all human life in the next century. "After decades of painstaking research, seemingly disparate paths into the sciences of molecular biology, chemistry, biology and genetics have converged. Suddenly the scientists realize that they are . . . at the peak of a mountain where all the surrounding landscape is clear to their view. They are confident now that they can tackle one of the biggest and most profound issues in their science: unravelling the message of human inheritance."--from the Preface The Human Genome Project has been called a scientific "search for the Holy Grail" or the genetics equivalent of the moon race. Thousands of researchers worldwide are analyzing the details of human DNA, hoping to identify all of the tens of thousands of human genes that are the blueprint for the human body. Physicist and writer Tom Wilkie offers a lively, compelling history of this scientifically fascinating and politically contentious undertaking. Beginning with the discovery of DNA by James Watson and Francis Crick in 1953, Wilkie's narrative unfolds with the intrigue of a detective story. He reviews in nontechnical terms the many step-by-step developments from different scientific teams that finally made it seem as if it would be possible to sequence the human genome. He goes on to consider the potential social consequences, good and bad, of learning to manipulate the human genetic code. What will happen as we try to prevent and cure disease or attempt to "improve" ourselves and our children by genetic means? A most readable introduction to the science of genetics and the potential consequences of the Human Genome Project, Perilous Knowledge provides background for the startling headlines that quite possibly signal changes to all human life in the next century. "After decades of painstaking research, seemingly disparate paths into the sciences of molecular biology, chemistry, biology and genetics have converged. Suddenly the scientists realize that they are . . . at the peak of a mountain where all the surrounding landscape is clear to their view. They are confident now that they can tackle one of the biggest and most profound issues in their science: unravelling the message of human inheritance."--from the Preface
Drawing The Map Of Life
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Author : Victor K. McElheny
language : en
Publisher: ReadHowYouWant.com
Release Date : 2010-10-19
Drawing The Map Of Life written by Victor K. McElheny and has been published by ReadHowYouWant.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-19 with Fiction categories.
Drawing the Map of Life is the dramatic story of the Human Genome Project from its origins, through the race to order the 3 billion subunits of DNA, to the surprises emerging as scientists seek to exploit the molecule of heredity. It's the first account to deal in depth with the intellectual roots of the project, the motivations that drove it, and the hype that often masked genuine triumphs. Distinguished science journalist Victor McElheny offers vivid, insightful profiles of key people, such as David Botstein, Eric Lander, Francis Collins, James Watson, Michael Hunkapiller, and Craig Venter. McElheny also shows that the Human Genome Project is a striking example of how new techniques (such as restriction enzymes and sequencing methods) often arrive first, shaping the questions scientists then ask. Drawing on years of original interviews and reporting in the inner circles of biological science, Drawing the Map of Life is the definitive, up-to-date story of today's greatest scientific quest. No one who wishes to understand genome mapping and how it is transforming our lives can afford to miss this book.
A Guide To The Human Genome Project
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Author : Susan L. Speaker
language : en
Publisher: Chemical Heritage Foundation
Release Date : 1993
A Guide To The Human Genome Project written by Susan L. Speaker and has been published by Chemical Heritage Foundation this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Science categories.
This simple, concise introduction to the HGP for the general reader explores the origins of the genome project and reactions in the scientific community; important technologies and techniques; institutions connected with the HGP, including designated genome centers, important suppliers of resources, and corporations; systems of communication; and ethical, legal, and social issues. A publication of the Biomolecular Sciences Initiative of CHF's Beckman Center for the History of Chemistry.
The Human Genome Project
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Author : Janey Levy
language : en
Publisher: Gareth Stevens Publishing LLLP
Release Date : 2018-12-15
The Human Genome Project written by Janey Levy and has been published by Gareth Stevens Publishing LLLP this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-15 with Juvenile Nonfiction categories.
The Human Genome Project was a groundbreaking, life-altering development of the late 20th century and a major evolution in science and medicine. Readers of this remarkable volume will follow the scientists of the international, collaborative research program as they map the human genome. They'll learn about the science behind the project as well as the scientific and medical possibilities opened by it. Vivid photographs support the fascinating text, and sidebars, fact boxes, and captions enrich your reader's experience.
The Human Genome Project
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Author : United States. Congress. House. Committee on Science. Subcommittee on Energy and Environment
language : en
Publisher:
Release Date : 2001
The Human Genome Project written by United States. Congress. House. Committee on Science. Subcommittee on Energy and Environment and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Science categories.