The Interleukin 10 Knockout Mouse Microform A Model For Studying Bone Metabolism During Intestinal Inflammation And The Effects Of Flaxseed Oil As A Nutritional Intervention
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The Interleukin 10 Knockout Mouse Microform A Model For Studying Bone Metabolism During Intestinal Inflammation And The Effects Of Flaxseed Oil As A Nutritional Intervention
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Author : Stacey Lynn Cohen
language : en
Publisher: Library and Archives Canada = Bibliothèque et Archives Canada
Release Date : 2004
The Interleukin 10 Knockout Mouse Microform A Model For Studying Bone Metabolism During Intestinal Inflammation And The Effects Of Flaxseed Oil As A Nutritional Intervention written by Stacey Lynn Cohen and has been published by Library and Archives Canada = Bibliothèque et Archives Canada this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
There is a high prevalence of osteoporosis among patients with inflammatory bowel disease (IBD). Interleukin-10-/- (IL-10) knockout (KO) mice spontaneously develop IBD. The objective of study 1 was to determine if IL-10 KO mice develop abnormalities in bone metabolism during intestinal inflammation and subsequently, in study 2, to determine if a 10% flaxseed oil would attenuate these bone abnormalities. In study 1, IL-10 KO mice had greater intestinal inflammation and elevated serum proinflammatory cytokines compared to wild type (WT) mice. IL-10 KO mice had bone abnormalities including lower bone mineral content (BMC) and density (BMD). In study 2, the FO diet did not attenuate the intestinal inflammation or serum cytokines. FO diet did not improve bone metabolism. In conclusion, the IL-10 KO mouse is a good model for studying inflammation-associated bone abnormalities and potential therapeutic interventions but flaxseed oil at the level used is not an effective dietary strategy in IL-10 KO mice.
Fundamentals Of Cancer Prevention
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Author : David Alberts
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-04-20
Fundamentals Of Cancer Prevention written by David Alberts and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-20 with Medical categories.
An authoritative work that provides a detailed review of the current status of practice and research in cancer prevention and control – an essential reference guide and tool for primary care physicians, the research community and students. Written as a collaborative work by the faculty of the nationally-renowned Cancer Prevention and Control Program at the Arizona Cancer Center, this book harnesses the expertise of researchers, investigators and clinicians in cancer prevention and control, to provide insights into this field for the benefit of nonspecialists.
Transform Methods For Solving Partial Differential Equations
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Author : Dean G. Duffy
language : en
Publisher: CRC Press
Release Date : 2004-07-15
Transform Methods For Solving Partial Differential Equations written by Dean G. Duffy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-15 with Mathematics categories.
Transform methods provide a bridge between the commonly used method of separation of variables and numerical techniques for solving linear partial differential equations. While in some ways similar to separation of variables, transform methods can be effective for a wider class of problems. Even when the inverse of the transform cannot be found ana
Storming Heaven A Novel
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Author : Denise Giardina
language : en
Publisher: W. W. Norton & Company
Release Date : 2010-07-05
Storming Heaven A Novel written by Denise Giardina and has been published by W. W. Norton & Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-05 with Fiction categories.
This is the story of the miners and the union they wanted, of the people who loved them and the people who wanted to kill their dreams. Annadel, West Virginia, was a small town rich in coal, farms, and close-knit families, all destroyed when the coal company came in. It stole everything it hadn't bothered to buy—land deeds, private homes, and ultimately, the souls of its men and women. Four people tell this powerful, deeply moving tale: Activist Mayor C. J. Marcum. Fierce, loveless union man Rondal Lloyd. Gutsy nurse Carrie Bishop, who loved Rondal. And lonely, Sicilian immigrant Rosa Angelelli, who lost four sons to the deadly mines. They all bear witness to nearly forgotten events of history, culminating in the final, tragic Battle of Blair Mountain—when the United States Army greeted ten thousand unemployed pro-union miners with airplanes, bombs, and poison gas. It was the first crucial battle of a war that has yet to be won.
The Zebrafish In Biomedical Research
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Author : Samuel Cartner
language : en
Publisher: Academic Press
Release Date : 2019-11-22
The Zebrafish In Biomedical Research written by Samuel Cartner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-22 with Science categories.
The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications Includes the work of world-renowned authors Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series
Phonetics Theory And Application
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Author : William R. Tiffany
language : en
Publisher: McGraw-Hill Humanities, Social Sciences & World Languages
Release Date : 1977
Phonetics Theory And Application written by William R. Tiffany and has been published by McGraw-Hill Humanities, Social Sciences & World Languages this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Language Arts & Disciplines categories.
Rigby Literacy
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Author :
language : en
Publisher: Rigby
Release Date : 2000
Rigby Literacy written by and has been published by Rigby this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Education categories.
Lauren shows her mom she is ready for the responsibility of taking care of a real dog by pretending her shoe is a dog. Her mom becomes convinced by Lauren's hard work and gives her a dog.
The Unquiet Earth
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Author : Denise Giardina
language : en
Publisher: Ivy Books
Release Date : 1994
The Unquiet Earth written by Denise Giardina and has been published by Ivy Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Coal miners categories.
"A flawless, fearless, great American story. It cuts a wide path through the worst and the best of what we are." BARBARA KINGSOLVER From the mining shanty towns of West Virginia comes this moving and passionate saga of a family, a community, and a way of life all but gone. In this coal-smudged place, Dillon, Rachel, and Jackie hopelessly intertwined in love and politics live in the shadow of the dying mines and the doomed union movement. Set against the devastation of the Depression, the fearful pulse of a world at war, the dawning hope of the War on Poverty, and, ultimately, the untamable force of nature herself, THE UNQUIET EARTH is a bold and bittersweet story of unforgettable men and women, and the times that made them great.
Alphaherpesviruses
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Author : Sandra Knowles Weller
language : en
Publisher: Caister Academic Press Limited
Release Date : 2011
Alphaherpesviruses written by Sandra Knowles Weller and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
Fresh From The Farm 6pk
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Author : Rigby
language : en
Publisher:
Release Date : 2006
Fresh From The Farm 6pk written by Rigby and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.