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The Interplay Of Gut Microbiome Between Infection And Inflammation


The Interplay Of Gut Microbiome Between Infection And Inflammation
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The Interplay Of Gut Microbiome Between Infection And Inflammation


The Interplay Of Gut Microbiome Between Infection And Inflammation
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Author : Piyush Baindara
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-21

The Interplay Of Gut Microbiome Between Infection And Inflammation written by Piyush Baindara and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-21 with Science categories.


Gut microbiome has become the greatest attraction of the research community in the recent past due to their diverse compositions and involvement in the regulation of human health and disease. With the development of high-throughput genomic analysis and other scientific advances, the gut microbiome has emerged as a potential therapeutic target for both infectious and autoimmune diseases. Especially, respiratory infections such as tuberculosis and COVID-19 have been shown to have a major impact on disease pathogenesis caused by gut dysbiosis which further affects the regulation of the gut-lung axis and contributes to disease progression. On the other hand, gut dysbiosis has been reported as a key player in multiple chronic diseases including gastrointestinal metabolic, neurological, cardiovascular, and respiratory inflammatory disease that includes diabetes, obesity, intestinal bowel disease, and cancer, etc. Despite, the known involvement, the mechanistic role of gut microbiota in disease pathogenesis is still undermined. The current research topic is focused on the mechanistic interplay of gut microbiota between infection and inflammation and thus overall disease progression. Strategies to overcome gut dysbiosis, gut microbiome transfer, the influence of antibiotics on the gut microbiome, modulation of gut microbiome via drug-repurposing, and host-directed therapies targeting the gut microbiome will also be discussed.



Microbiome Host Interactions


Microbiome Host Interactions
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Author : D. Dhanasekaran
language : en
Publisher: CRC Press
Release Date : 2021-04-01

Microbiome Host Interactions written by D. Dhanasekaran and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-01 with Medical categories.


Microbiota are a promising and fascinating subject in biology because they integrate the microbial communities in humans, animals, plants, and the environment. In humans, microbiota are associated with the gut, skin, and genital, oral, and respiratory organs. The plant microbial community is referred to as "holobiont," and it is influential in the maintenance and health of plants, which themselves play a role in animal health and the environment. The contents of Microbiome-Host Interactions cover all areas as well as new research trends in the fields of plant, animal, human, and environmental microbiome interactions. The book covers microbiota in polar soil environments, in health and disease, in Caenorhabditis elegans, and in agroecosystems, as well as in rice root and actinorhizal root nodules, speleothems, and marine shallow-water hydrothermal vents. Moreover, this book provides comprehensive accounts of advanced next-generation DNA sequencing, metagenomic techniques, high-throughput 16S rRNA sequencing, and understanding nucleic acid sequence data from fungal, algal, viral, bacterial, cyanobacterial, actinobacterial, and archaeal communities using QIIME software (Quantitative Insights into Microbial Ecology). FEATURES Summarizes recent insight in microbiota and host interactions in distinct habitats, including Antarctic, hydrothermal vents, speleothems, oral, skin, gut, feces, reproductive tract, soil, root, root nodules, forests, and mangroves Illustrates the high-throughput amplicon sequencing, computational techniques involved in the microbiota analysis, downstream analysis and visualization, and multivariate analysis commonly used for microbiome analysis Describes probiotics and prebiotics in the composition of the gut microbiota, skin microbiome impact in dermatologic disease prevention, and microbial communities in the reproductive tract of humans and animals Presents information in a reachable way for students, teachers, researchers, microbiologists, computational biologists, and other professionals who are interested in strengthening or enlarging their knowledge about microbiome analysis with next-generation DNA sequencing in the different branches of the sciences



The Lung Microbiome


The Lung Microbiome
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Author : Michael J. Cox
language : en
Publisher: European Respiratory Society
Release Date : 2019-03-01

The Lung Microbiome written by Michael J. Cox and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-01 with Medical categories.


Studying the lung microbiome requires a specialist approach to sampling, laboratory techniques and statistical analysis. This Monograph introduces the techniques used and discusses how respiratory sampling, 16S rRNA gene sequencing, metagenomics and the application of ecological theory can be used to examine the respiratory microbiome. It examines the different components of the respiratory microbiome: viruses and fungi in addition to the more frequently studied bacteria. It also considers a range of contexts from the paediatric microbiome and how this develops to disease of all ages including asthma and chronic obstructive pulmonary disease, chronic suppurative lung diseases, interstitial lung diseases, acquired pneumonias, transplantation, cancer and HIV, and the interaction of the respiratory microbiome and the environment.



Interplay Of Infection And Microbiome


Interplay Of Infection And Microbiome
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Author : Wilhelmina May Huston
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-06

Interplay Of Infection And Microbiome written by Wilhelmina May Huston and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-06 with categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



The Interplay Of Microbiome And Immune Response In Health And Diseases


The Interplay Of Microbiome And Immune Response In Health And Diseases
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Author : Gwendolyn Barcel´o-Coblijn
language : en
Publisher: MDPI
Release Date : 2019-11-06

The Interplay Of Microbiome And Immune Response In Health And Diseases written by Gwendolyn Barcel´o-Coblijn and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Medical categories.


[Increasing evidence suggests that microbiota and especially the gut microbiota (the microbes inhabiting the gut including bacteria, archaea, viruses, and fungi) plays a key role in human physiology and pathology. Recent findings indicate how dysbiosis—an imbalance in the composition and organization of microbial populations—could severely impact the development of different medical conditions (from metabolic to mood disorders), providing new insights into the comprehension of diverse diseases, such as IBD, obesity, asthma, autism, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber host cells, microbiota influences human physiology both functionally and structurally. Microbial metabolites bridge various—even distant—areas of the organism by way of the immune and hormone system. For instance, it is now clear that the mutual interaction between the gastrointestinal tract and the brain (gut–brain axis), often involves gut microbiota, indicating that the crosstalk between the organism and its microbial residents represents a fundamental aspect of both the establishment and maintenance of healthy conditions. Moreover, it is crucial to recognize that beyond the intestinal tract, microbiota populates other host organs and tissues (e.g., skin and oral mucosa). We have edited this eBook with the aim of publishing manuscripts focusing on the impact of microbiota in the development of different diseases and their associated treatments.]



Interplay Between Diets Microbiota Bacterial Metabolites And Host For Intestinal Health And Disease


Interplay Between Diets Microbiota Bacterial Metabolites And Host For Intestinal Health And Disease
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Author : Silvia Melgar
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-30

Interplay Between Diets Microbiota Bacterial Metabolites And Host For Intestinal Health And Disease written by Silvia Melgar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-30 with Medical categories.


An interplay between the diet and the microbiota appears to regulate the host responses. It is now well acknowledged that the microbiota and their metabolites such as short chain fatty acids, bile acids, etc modulates the metabolic status, educates the host’s intestinal immune system, and protects the host against invading pathogens and injury. Concomitantly, environmental factors such as diets and dietary components play a major role in shaping the microbiota, thereby modulating the host immune and epithelial responses, and ultimately directing the individual’s health status. Disruption in any of these elements or their interactions have been linked to the development and progression of a wide range of conditions including Inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), colorectal cancer, obesity, Parkinson’s disease, autism, asthma etc. While westernised diets (rich in fat/sugar and low in fibres) and dietary additives (e.g. emulsifiers) have been identified as risk factors for these disorders, other diets such as Mediterranean, Ketogenic and probiotics and prebiotics can serve as treatment strategies due to their impact on the microbiota and possibly the host.



Bacteria And Bacterial Metabolites Molecular Interplay With Gut Immunity


Bacteria And Bacterial Metabolites Molecular Interplay With Gut Immunity
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Author : Jun Fang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-21

Bacteria And Bacterial Metabolites Molecular Interplay With Gut Immunity written by Jun Fang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-21 with Science categories.




Systems Biology


Systems Biology
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Author : Michael G. Katze
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-01-04

Systems Biology written by Michael G. Katze and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-04 with Medical categories.


First, systems biology is an inter-disciplinary approach, requiring the combined talents of biologists, mathematicians, and computer scientists. Second, systems biology is holistic, with the goal of obtaining a comprehensive understanding of the workings of biological systems. This is achieved through the acquisition of massive amounts of data by high-throughput technologies—oligonucleotide microarrays, mass spectrometry, and next-generation sequencing—and the analysis of this data through sophisticated mathematical algorithms. It is perhaps the use of mathematics, to integrate abundant and diverse types of data and to generate models of interconnected molecular networks, that best characterizes systems biology.



The Gut Microbiome In Health And Disease


The Gut Microbiome In Health And Disease
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Author : Dirk Haller
language : en
Publisher: Springer
Release Date : 2018-07-27

The Gut Microbiome In Health And Disease written by Dirk Haller and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-27 with Medical categories.


The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.



State Of Research On The Interactions Between Food Additives The Gut Microbiome And The Host


State Of Research On The Interactions Between Food Additives The Gut Microbiome And The Host
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Author : Food and Agriculture Organization of the United Nations
language : en
Publisher: Food & Agriculture Org.
Release Date : 2025-05-22

State Of Research On The Interactions Between Food Additives The Gut Microbiome And The Host written by Food and Agriculture Organization of the United Nations and has been published by Food & Agriculture Org. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-22 with Social Science categories.


A scientific literature review was conducted with a focus on food safety to critically assess the current research on the impact of selected food additives on, and their interactions with the gut microbiome, as well as the resulting implications for host health. The review's main goals were to:> Gather and assess the quantity, quality, and reliability of scientific information,> Identify research limitations, knowledge gaps, and related needs,> Explore the applicability of microbiome data in food safety chemical risk assessments.This review concludes on recommendations to guide and improve microbiome science in risk assessment. Through this work, the Agrifood Systems and Food Safety Division contributes to the FAO’s role of improving food safety by encouraging high-quality research to produce robust data, promoting effective scientific communication, and investigating how knowledge regarding gut microbiome-food additive interactions could potentially support the modernization of food safety chemical risk assessments.