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The Leukemia Cell


The Leukemia Cell
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The Leukemia Cell


The Leukemia Cell
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Author : Arnold D. Rubin
language : en
Publisher:
Release Date : 1979

The Leukemia Cell written by Arnold D. Rubin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Cancer cells categories.




The Leukemia Lymphoma Cell Line Factsbook


The Leukemia Lymphoma Cell Line Factsbook
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Author : Hans G. Drexler
language : en
Publisher: Academic Press
Release Date : 2000-09-04

The Leukemia Lymphoma Cell Line Factsbook written by Hans G. Drexler and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-09-04 with Medical categories.


The Leukemia-Lymphoma Cell Line Factsbook represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provides the most important facts, using the succinct and user-friendly format that has made the FactsBooks so popular with scientists and clinical researchers. Introductory chapters provide background and perspective for culturing malignant hematopoietic (blood forming) cell lines. These chapters are followed by over 400 comprehensive individual entries. Each cell line entry highlights essential clinical, immunological, genetic, and functional features and includes a comprehensive listing of references. The full spectrum of malignant cell lines from all hematopoietic cell lineages Sister cell lines and relevant subclones Clinical data: patient, diagnosis, treatment status, and specimen source Authentication of derivation and availability Immunophenotype Cytogenetic karyotype Translocations and fusion genes Receptor gene rearrangements and genetic alterations Cell cultures aspects: establishment, medium, doubling time, growth Cytochemical profile Cytokine production and response to cytokines Proto-oncogene and transcription factor expression/alteration Functional features: differentiation induction, heterotransplantability Special unique features Key references



The Leukemic Cell


The Leukemic Cell
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Author : Daniel Catovsky
language : en
Publisher:
Release Date : 1991

The Leukemic Cell written by Daniel Catovsky and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.


This new edition includes two new chapters each on cell markers and DNA analysis. Also the role of ultrastructural morphology in immunocytochemistry is examined in greater detail than before and there is a new chapter on lymphoid malignancies. The emphasis is on practical approach.



Dynamic Morphology Of Leukemia Cells


Dynamic Morphology Of Leukemia Cells
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Author : H. Felix
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Dynamic Morphology Of Leukemia Cells written by H. Felix and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Dynamic Morphology is the attempt to correlate surface architec ture and shape of fixed cells, as visualized by scanning electron microscopy (SEM), with the behavior of living cells, recorded by microcinematography (MCM). If SEM and MCM are used concurrently for the analysis of cell populations, a dynamic inter pretation of SEM photographs is only valid if the experimental conditions are identical for the two techniques. This is achieved by allowing the cells to settle on a glass surface where they remain long enough to perform their various activities under conditions identical for both techniques (for technical details see Methodology). The analysis of a population necessitates the study of a large number of cells. This prerequisite is met by operating the scanning electron micro scope at low levels of magnification, and by using culture chambers for cinematography. It can be argued that the examina tion of attached cells excludes a complete SEM survey of a population, as cells not adhering from the outset or becoming detached during the different preparatory steps are lost. For this, cinematography proved to be a reliable control: All cell types recognized in time-lapse films were also seen in scanning electron (SE) micrographs. Another, and more general, objection to a dynamic interpretation concerns the artificiality of cellular behavior on glass. This is true, but does not invalidate compara tive studies making use of this substrate.



Treatment Of Leukemia And Lymphoma


Treatment Of Leukemia And Lymphoma
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Author : David A. Scheinberg
language : en
Publisher: Elsevier
Release Date : 2004-10-30

Treatment Of Leukemia And Lymphoma written by David A. Scheinberg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-30 with Medical categories.


New Treatments of Leukemia and Lymphoma describes the most important advances in the therapy of hematopoietic cancers that have been derived from recent discoveries in cancer cell biology, kinase biochemistry, and immunology. Detailed descriptions of the large number of new and effective agents that have recently become available for the treatment of leukemias and lymphomas as well as an understanding of their mechanisms of action and their integration into current therapy are provided. A number of experimental drug reagents currently in clinical investigation are also discussed. The therapies include conventional anti-metabolites, monoclonal antibodies directed to cell surface receptors, antibodies tagged with toxins and radiopharmaceuticals, inhibitors of specific kinases, stem cell transplants, and engineered T-cells designed to selectively target hematopoietic cancers. The contents of the book will allow practitioners and investigators alike to understand what is current and state of the art as well as what to look for in the future. * Provides an up-to-date, state of the art discussion of a rapidly changing field * Great breadth covering conventional chemotherapeutic agents, biologic agents such as antibodies, novel small molecule inhibitors and genetically engineered cells * Written by international experts in each of the fields



Acute Leukemias Vii


Acute Leukemias Vii
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Author : Wolfgang Hiddemann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Acute Leukemias Vii written by Wolfgang Hiddemann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The 7th volume of the book series Acute Leukemias provides new updates on the biology of acute leukemias and especially the underlying genetic and molecular events. High quality contributions are provided by leading scientists and clinicians making the book an excellent overview over most recent achievements which translate into new treatment strategies and hence an improved outlook for patients suffering from acute leukemias.



Cancer Cell Lines


Cancer Cell Lines
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Author : Bernhard Ø Palsson
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11

Cancer Cell Lines written by Bernhard Ø Palsson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.


This book describes all human leukemia-lymphoma cell lines that have been established and that grow continuously under standardised in vitro conditions. These lines are derived from cells belonging to all the major hematopoietic cell lineages, i.e. B- and T-lymphocytes, natural killer cells, granulocytic cells and megakaryocytic cells. The clinical data, the culture conditions and the major phenotypic features of the cell lines are described with citations. This book is the first book describing human leukemia-lymphoma cell lines and will be of interest to scientists involved in the areas of hematology, oncology, immunology, molecular biology and cytogenetics. Cancer Cell Lines, Volumes 1-3: These 3 volumes provide a comprehensive text on the culture of established cell lines from every type of human cancer. The volumes provide a basic manual and reference resource for every cancer research scientist using human cancer cells.



Focus On Leukemia Research


Focus On Leukemia Research
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Author : Rafael M. Romero
language : en
Publisher: Nova Publishers
Release Date : 2004

Focus On Leukemia Research written by Rafael M. Romero and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Leukemia categories.


This new book brings together leading research from around the globe. Leukaemia is cancer that begins in blood cells. In people with leukaemia, the bone marrow produces abnormal white blood cells. The abnormal cells are leukaemia cells. At first, leukaemia cells function almost normally. In time, they may crowd out normal white blood cells, red blood cells, and platelets. The scope of the book includes the four common types of leukaemia: chronic lymphocytic leukaemia (chronic lymphoblastic leukaemia, CLL) - most often affecting people over age 55; chronic myeloid leukaemia (chronic myelogenous leukaemia, CML) - affects mainly adults; acute lymphocytic leukaemia (acute lymphoblastic leukaemia, ALL) - the most common type of leukaemia in young children; and acute myeloid leukaemia (acute myelogenous leukaemia, AML) - which occurs in both adults and children. New advances in diagnosis, pathogenesis and therapy are also presented.



What You Need To Know About Leukemia


What You Need To Know About Leukemia
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Author :
language : en
Publisher:
Release Date : 1994

What You Need To Know About Leukemia written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Leukemia categories.




Targeted Therapy Of Acute Myeloid Leukemia


Targeted Therapy Of Acute Myeloid Leukemia
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Author : Michael Andreeff
language : en
Publisher: Springer
Release Date : 2014-11-20

Targeted Therapy Of Acute Myeloid Leukemia written by Michael Andreeff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-20 with Medical categories.


This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.